{"id":"https://openalex.org/W2146535530","doi":"https://doi.org/10.1093/infdis/151.3.388","title":"The Responsibility of the Infectious Disease Community for the Optimal Use of Antimicrobial Agents","display_name":"The Responsibility of the Infectious Disease Community for the Optimal Use of Antimicrobial Agents","publication_year":1985,"publication_date":"1985-03-01","ids":{"openalex":"https://openalex.org/W2146535530","doi":"https://doi.org/10.1093/infdis/151.3.388","mag":"2146535530","pmid":"https://pubmed.ncbi.nlm.nih.gov/3882848"},"language":"en","primary_location":{"id":"doi:10.1093/infdis/151.3.388","doi":"https://doi.org/10.1093/infdis/151.3.388","is_oa":false,"landing_page_url":"https://doi.org/10.1093/infdis/151.3.388","pdf_url":null,"source":{"id":"https://openalex.org/S54542293","display_name":"The Journal of Infectious Diseases","issn_l":"0022-1899","issn":["0022-1899","1537-6613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113769445","display_name":"Calvin M. Kunin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"C. M. Kunin","raw_affiliation_strings":["Department of Medicine, Ohio State University, Columbus, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Ohio State University, Columbus, Ohio","institution_ids":["https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5113769445"],"corresponding_institution_ids":["https://openalex.org/I52357470"],"apc_list":{"value":4763,"currency":"USD","value_usd":4763},"apc_paid":null,"fwci":68.4,"has_fulltext":false,"cited_by_count":107,"citation_normalized_percentile":{"value":1.0,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"151","issue":"3","first_page":"388","last_page":"398"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11649","display_name":"Pharmaceutical industry and healthcare","score":0.8003000020980835,"subfield":{"id":"https://openalex.org/subfields/2910","display_name":"Issues, ethics and legal aspects"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11649","display_name":"Pharmaceutical industry and healthcare","score":0.8003000020980835,"subfield":{"id":"https://openalex.org/subfields/2910","display_name":"Issues, ethics and legal aspects"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.19900000095367432,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antimicrobial-stewardship","display_name":"antimicrobial stewardship","score":0.8669999837875366},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.843999981880188},{"id":"https://openalex.org/keywords/pharmaceutical-industry-sponsorship","display_name":"pharmaceutical industry sponsorship","score":0.734000027179718},{"id":"https://openalex.org/keywords/industry-sponsored-trials","display_name":"industry-sponsored trials","score":0.781000018119812},{"id":"https://openalex.org/keywords/conflict-of-interest","display_name":"conflicts of interest","score":0.7599999904632568},{"id":"https://openalex.org/keywords/pharmaceutical-marketing","display_name":"pharmaceutical marketing","score":0.5260000228881836},{"id":"https://openalex.org/keywords/infectious-disease-physicians","display_name":"infectious disease physicians","score":0.492000013589859}],"concepts":[{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.7246659398078918},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.6849642992019653},{"id":"https://openalex.org/C2908569021","wikidata":"https://www.wikidata.org/wiki/Q2896740","display_name":"Anti-Infective Agents","level":3,"score":0.5287498831748962},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.51348477602005},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4669996500015259},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.45061978697776794},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35848772525787354},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3341354727745056},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.280924528837204},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24996629357337952},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1467403769493103}],"mesh":[{"descriptor_ui":"D000890","descriptor_name":"Anti-Infective Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000890","descriptor_name":"Anti-Infective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000890","descriptor_name":"Anti-Infective Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001424","descriptor_name":"Bacterial Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003365","descriptor_name":"Costs and Cost Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003906","descriptor_name":"Developing Countries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004345","descriptor_name":"Drug Industry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004352","descriptor_name":"Drug Resistance, Microbial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004363","descriptor_name":"Drug Utilization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007769","descriptor_name":"Lactams","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011292","descriptor_name":"Premedication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012958","descriptor_name":"Societies, Scientific","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/infdis/151.3.388","doi":"https://doi.org/10.1093/infdis/151.3.388","is_oa":false,"landing_page_url":"https://doi.org/10.1093/infdis/151.3.388","pdf_url":null,"source":{"id":"https://openalex.org/S54542293","display_name":"The Journal of Infectious Diseases","issn_l":"0022-1899","issn":["0022-1899","1537-6613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Infectious Diseases","raw_type":"journal-article"},{"id":"pmid:3882848","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3882848","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of infectious diseases","raw_type":"Clinical Trial"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.939.5747","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.939.5747","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jid.oxfordjournals.org/content/151/3/388.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W647092296","https://openalex.org/W1963782877","https://openalex.org/W1971398455","https://openalex.org/W1991836114","https://openalex.org/W1998612217","https://openalex.org/W2005881815","https://openalex.org/W2026152823","https://openalex.org/W2029577693","https://openalex.org/W2030973752","https://openalex.org/W2050714172","https://openalex.org/W2072041692","https://openalex.org/W2079907135","https://openalex.org/W2085068431","https://openalex.org/W2090454504","https://openalex.org/W2149514362","https://openalex.org/W2158383542","https://openalex.org/W2163268795","https://openalex.org/W2167257244","https://openalex.org/W2332987129","https://openalex.org/W2340644783","https://openalex.org/W2993119611","https://openalex.org/W3122318584"],"related_works":["https://openalex.org/W2028353278","https://openalex.org/W1974705098","https://openalex.org/W1971751716","https://openalex.org/W2107798274","https://openalex.org/W1910512275","https://openalex.org/W2275137564","https://openalex.org/W2312202268","https://openalex.org/W7096505065","https://openalex.org/W4400269753","https://openalex.org/W202403640"],"abstract_inverted_index":{"Antimicrobial":[0],"agents":[1,119],"are":[2,16,47,120],"a":[3,60,159],"critical":[4],"element":[5],"of":[6,10,52,81,130,133,161,179,185],"the":[7,36,40,50,72,86,107,131,136,172,183],"therapeutic":[8],"armamentarium":[9],"modern":[11],"medicine.":[12],"How":[13],"well":[14],"they":[15],"used":[17,124],"reflects":[18],"our":[19],"ability":[20],"to":[21,34,48,55,75],"treat":[22],"and":[23,54,94,123,135,170,188,195],"prevent":[24],"infectious":[25,64,82,146,186],"diseases.":[26],"The":[27,63,79],"major":[28,150],"consideration":[29],"for":[30,164,177],"proper":[31,41],"usage":[32],"is":[33,100,114,153],"select":[35],"optimal":[37],"agent":[38],"at":[39,59],"dosage.":[42],"Secondary,":[43],"but":[44],"important":[45],"concerns":[46],"minimize":[49],"emergence":[51],"resistance":[53],"provide":[56],"health":[57],"services":[58],"reasonable":[61],"cost.":[62],"disease":[65,83],"community":[66],"must":[67],"work":[68,166],"in":[69,92,139,174,182,192,196],"concert":[70],"with":[71,85,167],"pharmaceutical":[73],"industry":[74,87],"achieve":[76],"these":[77],"goals.":[78],"relations":[80],"physicians":[84,181],"have":[88,110,148],"been":[89,111],"remarkably":[90],"effective":[91],"evaluating":[93],"introducing":[95],"new":[96],"drugs,":[97],"however,":[98],"it":[99,152],"natural":[101],"that":[102,117,155],"conflicts":[103],"should":[104],"arise.":[105],"Although":[106],"overall":[108],"accomplishments":[109],"outstanding,":[112],"there":[113],"considerable":[115],"evidence":[116],"antimicrobial":[118,189],"often":[121],"abused":[122],"excessively.":[125],"This":[126],"paper":[127],"outlines":[128],"some":[129],"issues":[132],"marketing":[134],"problems":[137],"inherent":[138],"industry-sponsored":[140],"trials.":[141],"As":[142],"specialties":[143],"other":[144,180],"than":[145],"diseases":[147,187],"encountered":[149],"difficulties,":[151],"timely":[154],"this":[156,193],"society":[157],"adopts":[158],"code":[160],"ethical":[162],"conduct":[163],"its":[165],"industrial":[168],"sponsors":[169],"takes":[171],"initiative":[173],"developing":[175,197],"programs":[176],"education":[178],"field":[184],"therapy":[190],"both":[191],"country":[194],"nations.":[198]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}