{"id":"https://openalex.org/W2145683406","doi":"https://doi.org/10.1016/j.neulet.2014.03.052","title":"Exogenous fractalkine enhances proliferation of endothelial cells, promotes migration of endothelial progenitor cells and improves neurological deficits in a rat model of ischemic stroke","display_name":"Exogenous fractalkine enhances proliferation of endothelial cells, promotes migration of endothelial progenitor cells and improves neurological deficits in a rat model of ischemic stroke","publication_year":2014,"publication_date":"2014-04-01","ids":{"openalex":"https://openalex.org/W2145683406","doi":"https://doi.org/10.1016/j.neulet.2014.03.052","mag":"2145683406","pmid":"https://pubmed.ncbi.nlm.nih.gov/24704182"},"language":"en","primary_location":{"id":"doi:10.1016/j.neulet.2014.03.052","doi":"https://doi.org/10.1016/j.neulet.2014.03.052","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neulet.2014.03.052","pdf_url":null,"source":{"id":"https://openalex.org/S203050076","display_name":"Neuroscience Letters","issn_l":"0304-3940","issn":["0304-3940","1872-7972"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113718052","display_name":"Qin Wenjing","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113039","display_name":"Fifth Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/023te5r95","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210113039"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenjing Qin","raw_affiliation_strings":["Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China","Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China","institution_ids":["https://openalex.org/I4210113039"]},{"raw_affiliation_string":"Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China","institution_ids":["https://openalex.org/I4210113039"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100429975","display_name":"Qiang Li","orcid":"https://orcid.org/0000-0002-4384-8226","observed_orcids":["https://orcid.org/0000-0002-4384-8226","https://orcid.org/0000-0002-9559-2170"]},"institutions":[{"id":"https://openalex.org/I4210113039","display_name":"Fifth Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/023te5r95","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210113039"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhendong Li","raw_affiliation_strings":["Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China. Electronic address: lizdsysu@163.com","Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China. Electronic address: lizdsysu@163.com","institution_ids":["https://openalex.org/I4210113039"]},{"raw_affiliation_string":"Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China","institution_ids":["https://openalex.org/I4210113039"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shijian Luo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113039","display_name":"Fifth Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/023te5r95","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210113039"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shijian Luo","raw_affiliation_strings":["Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China","Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China","institution_ids":["https://openalex.org/I4210113039"]},{"raw_affiliation_string":"Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China","institution_ids":["https://openalex.org/I4210113039"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102018665","display_name":"Rui Wu","orcid":"https://orcid.org/0009-0008-8707-4075","observed_orcids":["https://orcid.org/0009-0008-8707-4075"]},"institutions":[{"id":"https://openalex.org/I4210113039","display_name":"Fifth Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/023te5r95","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210113039"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Wu","raw_affiliation_strings":["Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China","Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China","institution_ids":["https://openalex.org/I4210113039"]},{"raw_affiliation_string":"Department of Neurology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China","institution_ids":["https://openalex.org/I4210113039"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101770693","display_name":"Zhong Pei","orcid":"https://orcid.org/0000-0002-7986-3452","observed_orcids":["https://orcid.org/0000-0002-7986-3452","https://orcid.org/0000-0002-8425-2867"]},"institutions":[{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhong Pei","raw_affiliation_strings":["Department of Neurology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China","Department of Neurology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou,510080, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China","institution_ids":["https://openalex.org/I4210128921"]},{"raw_affiliation_string":"Department of Neurology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou,510080, China","institution_ids":["https://openalex.org/I4210128921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102360426","display_name":"Ruxun Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruxun Huang","raw_affiliation_strings":["Department of Neurology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China","Department of Neurology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou,510080, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China","institution_ids":["https://openalex.org/I4210128921"]},{"raw_affiliation_string":"Department of Neurology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou,510080, China","institution_ids":["https://openalex.org/I4210128921"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100429975"],"corresponding_institution_ids":["https://openalex.org/I4210113039"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":null,"fwci":1.8254,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.83338847,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"569","issue":null,"first_page":"80","last_page":"84"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.43529999256134033,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.43529999256134033,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.18809999525547028,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.15299999713897705,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cx3cl1","display_name":"fractalkine","score":0.9940000176429749},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9559999704360962},{"id":"https://openalex.org/keywords/middle-cerebral-artery-occlusion","display_name":"middle cerebral artery occlusion","score":0.8059999942779541},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.6990000009536743},{"id":"https://openalex.org/keywords/neovascularization","display_name":"neovascularization","score":0.9390000104904175},{"id":"https://openalex.org/keywords/endothelial-cell-proliferation","display_name":"endothelial cell proliferation","score":0.972000002861023},{"id":"https://openalex.org/keywords/endothelial-progenitor-cells","display_name":"endothelial progenitor cells","score":0.9539999961853027},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.9760000109672546},{"id":"https://openalex.org/keywords/neurological-deficit","display_name":"neurological deficit","score":0.6100000143051147},{"id":"https://openalex.org/keywords/cerebral-infarct-size","display_name":"cerebral infarct size","score":0.8460000157356262},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.8640000224113464},{"id":"https://openalex.org/keywords/intracerebroventricular-injection","display_name":"intracerebroventricular administration","score":0.8389999866485596},{"id":"https://openalex.org/keywords/peri-infarct-zone","display_name":"peri-infarct zone","score":0.7070000171661377}],"concepts":[{"id":"https://openalex.org/C2780577055","wikidata":"https://www.wikidata.org/wiki/Q2069532","display_name":"Penumbra","level":3,"score":0.8606299161911011},{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.7074090242385864},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.6785701513290405},{"id":"https://openalex.org/C82321936","wikidata":"https://www.wikidata.org/wiki/Q14907780","display_name":"CX3CL1","level":5,"score":0.6770151853561401},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6537346243858337},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.5782493352890015},{"id":"https://openalex.org/C2778271429","wikidata":"https://www.wikidata.org/wiki/Q1281049","display_name":"Neovascularization","level":3,"score":0.5777010321617126},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.5656415820121765},{"id":"https://openalex.org/C2780152582","wikidata":"https://www.wikidata.org/wiki/Q1340830","display_name":"Endothelial progenitor cell","level":4,"score":0.5484344959259033},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.5413370728492737},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.48327523469924927},{"id":"https://openalex.org/C2775841333","wikidata":"https://www.wikidata.org/wiki/Q498179","display_name":"Middle cerebral artery","level":3,"score":0.47488468885421753},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.42122048139572144},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4099915623664856},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31088435649871826},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.22189787030220032},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.19960570335388184},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19148120284080505},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.1675461232662201},{"id":"https://openalex.org/C12823836","wikidata":"https://www.wikidata.org/wiki/Q24720618","display_name":"Chemokine receptor","level":4,"score":0.06278473138809204},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D007276","descriptor_name":"Injections, Intraventricular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007276","descriptor_name":"Injections, Intraventricular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007276","descriptor_name":"Injections, Intraventricular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018696","descriptor_name":"Neuroprotective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018696","descriptor_name":"Neuroprotective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018696","descriptor_name":"Neuroprotective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018696","descriptor_name":"Neuroprotective Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D018696","descriptor_name":"Neuroprotective Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D018696","descriptor_name":"Neuroprotective Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D018919","descriptor_name":"Neovascularization, Physiologic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018919","descriptor_name":"Neovascularization, Physiologic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018919","descriptor_name":"Neovascularization, Physiologic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054428","descriptor_name":"Chemokine CX3CL1","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D054428","descriptor_name":"Chemokine CX3CL1","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D054428","descriptor_name":"Chemokine CX3CL1","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D054428","descriptor_name":"Chemokine CX3CL1","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D054428","descriptor_name":"Chemokine CX3CL1","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D054428","descriptor_name":"Chemokine CX3CL1","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.neulet.2014.03.052","doi":"https://doi.org/10.1016/j.neulet.2014.03.052","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neulet.2014.03.052","pdf_url":null,"source":{"id":"https://openalex.org/S203050076","display_name":"Neuroscience Letters","issn_l":"0304-3940","issn":["0304-3940","1872-7972"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience Letters","raw_type":"journal-article"},{"id":"pmid:24704182","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24704182","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5400000214576721}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321160","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71"},{"id":"https://openalex.org/F4320321921","display_name":"Natural Science Foundation of Guangdong Province","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1546864953","https://openalex.org/W1964210744","https://openalex.org/W1973757232","https://openalex.org/W1974135000","https://openalex.org/W1978890792","https://openalex.org/W1984115097","https://openalex.org/W1988086690","https://openalex.org/W2000673488","https://openalex.org/W2004264059","https://openalex.org/W2004872316","https://openalex.org/W2014495235","https://openalex.org/W2024285156","https://openalex.org/W2053012673","https://openalex.org/W2053704719","https://openalex.org/W2057269156","https://openalex.org/W2062595499","https://openalex.org/W2065456584","https://openalex.org/W2076844289","https://openalex.org/W2095885953","https://openalex.org/W2096330567","https://openalex.org/W2100293635","https://openalex.org/W2104693571","https://openalex.org/W2117914751","https://openalex.org/W2119368421","https://openalex.org/W2121567769","https://openalex.org/W2126088489","https://openalex.org/W2129282529","https://openalex.org/W2148809826","https://openalex.org/W2154496067","https://openalex.org/W2163487275","https://openalex.org/W2166615294","https://openalex.org/W2167476293","https://openalex.org/W2168956313","https://openalex.org/W2169612578","https://openalex.org/W4254041558"],"related_works":["https://openalex.org/W2051762050","https://openalex.org/W2081332141","https://openalex.org/W2378129912","https://openalex.org/W1967035072","https://openalex.org/W2903851650","https://openalex.org/W2361522534","https://openalex.org/W3028828100","https://openalex.org/W2082832641","https://openalex.org/W2055127670","https://openalex.org/W2373923409"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-24T09:50:30.924529","created_date":"2025-10-10T00:00:00"}