{"id":"https://openalex.org/W2145674155","doi":"https://doi.org/10.1021/js960523y","title":"Percutaneous Absorption of Sunscreen Agents from Liquid Paraffin: Self-Association of Octyl Salicylate and Effects on Skin Flux","display_name":"Percutaneous Absorption of Sunscreen Agents from Liquid Paraffin: Self-Association of Octyl Salicylate and Effects on Skin Flux","publication_year":1997,"publication_date":"1997-07-01","ids":{"openalex":"https://openalex.org/W2145674155","doi":"https://doi.org/10.1021/js960523y","mag":"2145674155","pmid":"https://pubmed.ncbi.nlm.nih.gov/9232518"},"language":"en","primary_location":{"id":"doi:10.1021/js960523y","doi":"https://doi.org/10.1021/js960523y","is_oa":false,"landing_page_url":"https://doi.org/10.1021/js960523y","pdf_url":null,"source":{"id":"https://openalex.org/S130661733","display_name":"Journal of Pharmaceutical Sciences","issn_l":"0022-3549","issn":["0022-3549","1520-6017"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057240264","display_name":"Ruoying Jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Ruoying Jiang","raw_affiliation_strings":["School of Pharmacy, University of Queensland, St. Lucia, Brisbane, Australia","School of Pharmacy, University of Queensland, St Lucia, Brisbane QLD 4072, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, University of Queensland, St. Lucia, Brisbane, Australia","institution_ids":["https://openalex.org/I165143802"]},{"raw_affiliation_string":"School of Pharmacy, University of Queensland, St Lucia, Brisbane QLD 4072, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064284123","display_name":"Michael Stephen Roberts","orcid":"https://orcid.org/0000-0003-3894-5301","observed_orcids":["https://orcid.org/0000-0003-3894-5301","https://orcid.org/0000-0002-5837-246X"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]},{"id":"https://openalex.org/I2801814493","display_name":"Princess Alexandra Hospital","ror":"https://ror.org/04mqb0968","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2801244131","https://openalex.org/I2801814493","https://openalex.org/I4210089726"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Michael S. Roberts","raw_affiliation_strings":["Department of Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane, Qld 4102, Australia","#N#        Department of Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane, Qld 4102, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane, Qld 4102, Australia","institution_ids":["https://openalex.org/I165143802","https://openalex.org/I2801814493"]},{"raw_affiliation_string":"#N#        Department of Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane, Qld 4102, Australia","institution_ids":["https://openalex.org/I165143802","https://openalex.org/I2801814493"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113661238","display_name":"Richard J. Prankerd","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Richard J. Prankerd","raw_affiliation_strings":["School of Pharmacy, University of Queensland, St. Lucia, Brisbane, Qld 4072, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, University of Queensland, St. Lucia, Brisbane, Qld 4072, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112094425","display_name":"Heather AE Benson","orcid":"https://orcid.org/0000-0002-1818-5627","observed_orcids":["https://orcid.org/0000-0002-1818-5627"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Heather A.E. Benson","raw_affiliation_strings":["School of Pharmacy, University of Queensland, St. Lucia, Brisbane, Qld 4072, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, University of Queensland, St. Lucia, Brisbane, Qld 4072, Australia","institution_ids":["https://openalex.org/I165143802"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5112094425"],"corresponding_institution_ids":["https://openalex.org/I165143802"],"apc_list":{"value":3620,"currency":"USD","value_usd":3620},"apc_paid":null,"fwci":2.9081,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.91307255,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"86","issue":"7","first_page":"791","last_page":"796"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/octyl-salicylate","display_name":"octyl salicylate","score":0.9959999918937683},{"id":"https://openalex.org/keywords/uv-filters","display_name":"UV filters","score":0.9919999837875366},{"id":"https://openalex.org/keywords/skin-absorption","display_name":"percutaneous absorption","score":0.949999988079071},{"id":"https://openalex.org/keywords/liquid-paraffin","display_name":"liquid paraffin","score":0.906000018119812},{"id":"https://openalex.org/keywords/self-association","display_name":"self-association","score":0.8119999766349792},{"id":"https://openalex.org/keywords/skin-permeability","display_name":"skin permeability","score":0.9259999990463257},{"id":"https://openalex.org/keywords/partition-coefficient","display_name":"partition coefficient","score":0.6359999775886536},{"id":"https://openalex.org/keywords/apparent-permeability-coefficient","display_name":"apparent permeability coefficient","score":0.7229999899864197},{"id":"https://openalex.org/keywords/human-epidermis","display_name":"human epidermis","score":0.7179999947547913},{"id":"https://openalex.org/keywords/synthetic-membranes","display_name":"synthetic membranes","score":0.8199999928474426},{"id":"https://openalex.org/keywords/silicone-membrane","display_name":"silicone membrane","score":0.4620000123977661},{"id":"https://openalex.org/keywords/bovine-serum-albumin","display_name":"bovine serum albumin","score":0.7390000224113464},{"id":"https://openalex.org/keywords/molecular-modeling","display_name":"molecular modeling","score":0.3610000014305115}],"concepts":[{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.7405024766921997},{"id":"https://openalex.org/C2993661896","wikidata":"https://www.wikidata.org/wiki/Q6557468","display_name":"Liquid paraffin","level":2,"score":0.7315330505371094},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6072215437889099},{"id":"https://openalex.org/C50670333","wikidata":"https://www.wikidata.org/wiki/Q907651","display_name":"Permeation","level":3,"score":0.5794259309768677},{"id":"https://openalex.org/C192552737","wikidata":"https://www.wikidata.org/wiki/Q898797","display_name":"Partition coefficient","level":2,"score":0.5262348055839539},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5241846442222595},{"id":"https://openalex.org/C108458091","wikidata":"https://www.wikidata.org/wiki/Q2033818","display_name":"Low-density polyethylene","level":3,"score":0.5241228342056274},{"id":"https://openalex.org/C181748761","wikidata":"https://www.wikidata.org/wiki/Q2641430","display_name":"High-density polyethylene","level":3,"score":0.4955822229385376},{"id":"https://openalex.org/C125287762","wikidata":"https://www.wikidata.org/wiki/Q1758948","display_name":"Absorption (acoustics)","level":2,"score":0.48558133840560913},{"id":"https://openalex.org/C120882062","wikidata":"https://www.wikidata.org/wiki/Q28352","display_name":"Permeability (electromagnetism)","level":3,"score":0.48236221075057983},{"id":"https://openalex.org/C2777459323","wikidata":"https://www.wikidata.org/wiki/Q5259911","display_name":"Human skin","level":2,"score":0.4695582687854767},{"id":"https://openalex.org/C86807702","wikidata":"https://www.wikidata.org/wiki/Q2620381","display_name":"Bovine serum albumin","level":2,"score":0.42840272188186646},{"id":"https://openalex.org/C2779751980","wikidata":"https://www.wikidata.org/wiki/Q143429","display_name":"Polyethylene","level":2,"score":0.25486886501312256},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.23173290491104126},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2046903669834137},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.18567433953285217},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1408313512802124},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008567","descriptor_name":"Membranes, Artificial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010232","descriptor_name":"Paraffin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010539","descriptor_name":"Permeability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010592","descriptor_name":"Pharmaceutic Aids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011095","descriptor_name":"Polyethylenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012459","descriptor_name":"Salicylates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012459","descriptor_name":"Salicylates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012828","descriptor_name":"Silicones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012869","descriptor_name":"Skin Absorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013473","descriptor_name":"Sunscreening Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013473","descriptor_name":"Sunscreening Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/js960523y","doi":"https://doi.org/10.1021/js960523y","is_oa":false,"landing_page_url":"https://doi.org/10.1021/js960523y","pdf_url":null,"source":{"id":"https://openalex.org/S130661733","display_name":"Journal of Pharmaceutical Sciences","issn_l":"0022-3549","issn":["0022-3549","1520-6017"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Sciences","raw_type":"journal-article"},{"id":"pmid:9232518","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9232518","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pharmaceutical sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320984","display_name":"University of Queensland","ror":"https://ror.org/00rqy9422"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W78463179","https://openalex.org/W132347858","https://openalex.org/W324588880","https://openalex.org/W1560694348","https://openalex.org/W1975572006","https://openalex.org/W1995776738","https://openalex.org/W1999044704","https://openalex.org/W2009111826","https://openalex.org/W2020032003","https://openalex.org/W2063352195","https://openalex.org/W2063816876","https://openalex.org/W2071914055","https://openalex.org/W2117194085","https://openalex.org/W2169709578"],"related_works":["https://openalex.org/W2040176397","https://openalex.org/W2085375026","https://openalex.org/W7072026732","https://openalex.org/W324588880","https://openalex.org/W2039455972","https://openalex.org/W1603898777","https://openalex.org/W2007943469","https://openalex.org/W2018905949","https://openalex.org/W2094962283","https://openalex.org/W19219056"],"abstract_inverted_index":{"This":[0],"study":[1],"provides":[2],"an":[3],"investigation":[4],"of":[5,8,22,43,64,91,166],"the":[6,20,33,110,133,137,145,173,179,183],"availability":[7],"octyl":[9],"salicylate":[10],"(OS),":[11],"a":[12],"common":[13],"sunscreen":[14],"agent,":[15],"from":[16,36,94,132,186],"liquid":[17,46,68],"paraffin":[18,47,69],"and":[19,48,75,86,96,117,126,154,172],"effect":[21,35],"OS":[23,44,60,65,92,167],"on":[24],"skin":[25],"permeability.":[26],"A":[27,62],"model":[28],"membrane":[29,37,116,147],"system":[30],"to":[31,103,182],"isolate":[32],"vehicle":[34],"permeability":[38,128],"has":[39],"been":[40],"developed.":[41],"Partitioning":[42],"between":[45],"aqueous":[49],"receptor":[50],"phases":[51],"was":[52,70],"conducted.":[53],"Partition":[54],"coefficients":[55,129],"increased":[56],"with":[57,140,170],"increase":[58,151],"in":[59,67,83,152],"concentration.":[61],"range":[63],"concentrations":[66,157],"diffused":[71],"across":[72],"human":[73,118],"epidermis":[74,119],"synthetic":[76],"membranes":[77,100],"into":[78],"4%":[79],"bovine":[80],"serum":[81],"albumin":[82],"phosphate-buffered":[84],"saline":[85],"50%":[87],"ethanol.":[88],"Absorption":[89],"profiles":[90],"obtained":[93,131],"silicone":[95],"low-density":[97],"polyethylene":[98,112],"(LDPE)":[99],"were":[101,168],"similar":[102],"each":[104],"other":[105],"but":[106],"higher":[107],"than":[108],"for":[109,144],"high-density":[111],"[HDPE":[113],"(3":[114],"times)]":[115],"(15":[120],"times).":[121],"The":[122],"steady":[123],"state":[124],"fluxes":[125],"apparent":[127],"(Kp')":[130],"diffusion":[134],"studies":[135],"showed":[136,149,162],"same":[138],"trends":[139],"all":[141],"membranes,":[142],"except":[143],"HDPE":[146],"which":[148],"greater":[150],"flux":[153],"Kp'":[155],"at":[156],"above":[158],"30%.":[159],"IR":[160],"spectra":[161],"that":[163,178],"several":[164],"bands":[165],"shifted":[169],"concentrations,":[171],"molecular":[174],"models":[175],"further":[176],"suggested":[177],"main":[180],"contribution":[181],"self-association":[184],"is":[185],"non-1,4":[187],"van":[188],"der":[189],"Waals":[190],"interactions.":[191]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}