{"id":"https://openalex.org/W2145448140","doi":"https://doi.org/10.1161/strokeaha.107.496588","title":"Metabolic Syndrome and Ischemic Stroke Risk","display_name":"Metabolic Syndrome and Ischemic Stroke Risk","publication_year":2007,"publication_date":"2007-12-06","ids":{"openalex":"https://openalex.org/W2145448140","doi":"https://doi.org/10.1161/strokeaha.107.496588","mag":"2145448140","pmid":"https://pubmed.ncbi.nlm.nih.gov/18063821","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2677015"},"language":"en","primary_location":{"id":"doi:10.1161/strokeaha.107.496588","doi":"https://doi.org/10.1161/strokeaha.107.496588","is_oa":false,"landing_page_url":"https://doi.org/10.1161/strokeaha.107.496588","pdf_url":null,"source":{"id":"https://openalex.org/S62532593","display_name":"Stroke","issn_l":"0039-2499","issn":["0039-2499","1524-4628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stroke","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2677015","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038584263","display_name":"Bernadette M Boden-Albala","orcid":"https://orcid.org/0000-0002-3752-329X","observed_orcids":["https://orcid.org/0000-0002-3752-329X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bernadette Boden-Albala","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109957867","display_name":"Ralph L. Sacco","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ralph L. Sacco","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055549855","display_name":"Hye-Sueng Lee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hye-Sueng Lee","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002574514","display_name":"Cairistine N Grahame-Clarke","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cairistine Grahame-Clarke","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026734876","display_name":"Tatjana Rundek","orcid":"https://orcid.org/0000-0002-7115-9815","observed_orcids":["https://orcid.org/0000-0002-7115-9815"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tanja Rundek","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113514048","display_name":"Mitchell S.V. Elkind","orcid":"https://orcid.org/0000-0003-2562-1156","observed_orcids":["https://orcid.org/0000-0003-2562-1156"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mitchell V. Elkind","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044706338","display_name":"Clinton B. Wright","orcid":"https://orcid.org/0000-0002-9797-6215","observed_orcids":["https://orcid.org/0000-0002-9797-6215"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Clinton Wright","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067408965","display_name":"Elsa\u2010Grace V. Giardina","orcid":"https://orcid.org/0000-0003-2170-6347","observed_orcids":["https://orcid.org/0000-0003-2170-6347"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elsa-Grace V. Giardina","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035907158","display_name":"Marco R. Di Tullio","orcid":"https://orcid.org/0000-0002-3031-4196","observed_orcids":["https://orcid.org/0000-0002-3031-4196"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marco R. DiTullio","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111631784","display_name":"Shunichi Homma","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shunichi Homma","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024491002","display_name":"Myunghee Cho Paik","orcid":"https://orcid.org/0000-0001-6239-4883","observed_orcids":["https://orcid.org/0000-0001-6239-4883"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Myunghee C. Paik","raw_affiliation_strings":["From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Neurology (B.B.-A., R.L.S., T.R., M.V.E., C.W.) and Sociomedical Science (B.B.-A.), the Sergievsky Center (R.L.S., M.V.E.), and the Departments of Epidemiology (R.L.S.), Biostatistics (M.C.P., H.-S.L.), and Medicine, Division of Cardiology (C.G.-C., E.-G.V.G., M.R.D.T., S.H.), Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":13.4001,"has_fulltext":false,"cited_by_count":265,"citation_normalized_percentile":{"value":0.9913118,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"39","issue":"1","first_page":"30","last_page":"35"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.8389000296592712,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.8389000296592712,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.14749999344348907,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":1.0},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9860000014305115},{"id":"https://openalex.org/keywords/stroke-risk","display_name":"stroke risk","score":0.7419999837875366},{"id":"https://openalex.org/keywords/vascular-events","display_name":"vascular events","score":0.800000011920929},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.9760000109672546},{"id":"https://openalex.org/keywords/vascular-mortality","display_name":"vascular death","score":0.8109999895095825},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.9819999933242798},{"id":"https://openalex.org/keywords/racial-and-ethnic-differences","display_name":"racial and ethnic differences","score":0.9300000071525574},{"id":"https://openalex.org/keywords/hispanic-population","display_name":"Hispanic population","score":0.6340000033378601},{"id":"https://openalex.org/keywords/northern-manhattan-study","display_name":"Northern Manhattan Study","score":0.8450000286102295},{"id":"https://openalex.org/keywords/population-attributable-fraction","display_name":"population attributable fraction","score":0.8050000071525574},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9614611864089966},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.6663150787353516},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.6277568936347961},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.5885690450668335},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4033859968185425},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.38697880506515503},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.34404194355010986},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.17331907153129578},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001741","descriptor_name":"Black or African American","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006630","descriptor_name":"Hispanic or Latino","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009519","descriptor_name":"New York City","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012727","descriptor_name":"Sex Characteristics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D044383","descriptor_name":"Black People","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1161/strokeaha.107.496588","doi":"https://doi.org/10.1161/strokeaha.107.496588","is_oa":false,"landing_page_url":"https://doi.org/10.1161/strokeaha.107.496588","pdf_url":null,"source":{"id":"https://openalex.org/S62532593","display_name":"Stroke","issn_l":"0039-2499","issn":["0039-2499","1524-4628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stroke","raw_type":"journal-article"},{"id":"pmid:18063821","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18063821","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stroke","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:2677015","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2677015","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Stroke","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2677015","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2677015","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Stroke","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6200000047683716}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2015165407","display_name":null,"funder_award_id":"NS-29993","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3354701518","display_name":"Vascular Determinants of Dementia and Cognitive Decline in a Tri-Ethnic Region","funder_award_id":"R56NS029993","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G4300124716","display_name":"Stroke Incidence and Risk Factors in a Tri-Ethnic Region","funder_award_id":"R37NS029993","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G5557144014","display_name":"Risk Factors for Stroke and Cognitive Decline in a Tri-Ethnic Region","funder_award_id":"R01NS029993","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G6936619","display_name":null,"funder_award_id":"R01-29993","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"}],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W10901539","https://openalex.org/W1986349550","https://openalex.org/W1986432871","https://openalex.org/W1996564597","https://openalex.org/W1997125030","https://openalex.org/W2003441385","https://openalex.org/W2032119684","https://openalex.org/W2059399372","https://openalex.org/W2060449981","https://openalex.org/W2065227060","https://openalex.org/W2078807483","https://openalex.org/W2079679899","https://openalex.org/W2084156043","https://openalex.org/W2086501057","https://openalex.org/W2096773810","https://openalex.org/W2098690816","https://openalex.org/W2124073607","https://openalex.org/W2129244743","https://openalex.org/W2147098206","https://openalex.org/W2159793865","https://openalex.org/W2415125003","https://openalex.org/W2607031541","https://openalex.org/W4238251256","https://openalex.org/W4249825849"],"related_works":["https://openalex.org/W2001173327","https://openalex.org/W4389411523","https://openalex.org/W1566235841","https://openalex.org/W3036333861","https://openalex.org/W1971098012","https://openalex.org/W2592517772","https://openalex.org/W2330666983","https://openalex.org/W2051934806","https://openalex.org/W2005407792","https://openalex.org/W187613844"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"PURPOSE:":[2],"More":[3,117],"than":[4,118,142,199],"47":[5],"million":[6],"individuals":[7],"in":[8,28,234,238,246],"the":[9,13,16,22,40,68,107,113,121,124,183,229],"United":[10],"States":[11],"meet":[12],"criteria":[14],"for":[15,52,90,175,265],"metabolic":[17,23,59,114,125,149,184,230,258],"syndrome.":[18,115],"The":[19,58,103,148,180,221,257],"relation":[20],"between":[21],"syndrome":[24,60,126,150,185,231,259],"and":[25,87,93,164,177,207,219,248,273],"stroke":[26,92,157,187,245,253],"risk":[27,155,178,188,263],"multiethnic":[29],"populations":[30],"has":[31],"not":[32],"been":[33],"well":[34],"characterized.":[35],"METHODS:":[36],"As":[37],"part":[38],"of":[39,55,109,120,128,132,156,182,228,244,252],"Northern":[41],"Manhattan":[42],"Study,":[43],"3298":[44],"stroke-free":[45],"community":[46],"residents":[47],"were":[48,80],"prospectively":[49],"followed":[50],"up":[51],"a":[53,235,241,249],"mean":[54],"6.4":[56],"years.":[57],"was":[61,136,151,189],"defined":[62],"according":[63],"to":[64,82,112,162,171,197,205,214],"guidelines":[65],"established":[66],"by":[67,271],"National":[69],"Cholesterol":[70],"Education":[71],"Program":[72],"Adult":[73],"Treatment":[74],"Panel":[75],"III.":[76],"Cox":[77],"proportional-hazards":[78],"models":[79],"used":[81],"calculate":[83],"hazard":[84],"ratios":[85],"(HRs)":[86],"95%":[88,159,168,194,202,211],"CIs":[89],"ischemic":[91,266],"vascular":[94,101,165],"events":[95,110,166],"(ischemic":[96],"stroke,":[97,240,267],"myocardial":[98],"infarction,":[99],"or":[100,145],"death).":[102],"etiologic":[104,222],"fraction":[105,223],"estimates":[106,224],"proportion":[108],"attributable":[111],"RESULTS:":[116],"44%":[119],"cohort":[122],"had":[123],"(48%":[127],"women":[129,192],"vs":[130],"38%":[131],"men,":[133],"P<0.0001),":[134],"which":[135],"more":[137],"prevalent":[138],"among":[139,191,208,254],"Hispanics":[140,209],"(50%)":[141],"whites":[143],"(39%)":[144],"blacks":[146,218],"(37%).":[147],"associated":[152],"with":[153,217,268],"increased":[154],"(HR=1.5;":[158],"CI,":[160,169,195,203,212],"1.1":[161],"2.2)":[163],"(HR=1.6;":[167],"1.3":[170,196],"2.0)":[172],"after":[173],"adjustment":[174],"sociodemographic":[176],"factors.":[179],"effect":[181],"on":[186],"greater":[190],"(HR=2.0;":[193,210],"3.1)":[198],"men":[200],"(HR=1.1;":[201],"0.6":[204],"1.9)":[206],"1.2":[213],"3.4)":[215],"compared":[216],"whites.":[220],"suggest":[225],"that":[226],"elimination":[227],"would":[232],"result":[233],"19%":[236],"reduction":[237,243,251],"overall":[239],"30%":[242],"women;":[247],"35%":[250],"Hispanics.":[255],"CONCLUSIONS:":[256],"is":[260],"an":[261],"important":[262],"factor":[264],"differential":[269],"effects":[270],"sex":[272],"race/ethnicity.":[274]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":20},{"year":2014,"cited_by_count":20},{"year":2013,"cited_by_count":24},{"year":2012,"cited_by_count":17}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
