{"id":"https://openalex.org/W2145307090","doi":"https://doi.org/10.1002/lsm.10040","title":"Enhanced adenoviral\u2010vector mediated gene transfer using human albumin solder","display_name":"Enhanced adenoviral\u2010vector mediated gene transfer using human albumin solder","publication_year":2002,"publication_date":"2002-03-25","ids":{"openalex":"https://openalex.org/W2145307090","doi":"https://doi.org/10.1002/lsm.10040","mag":"2145307090","pmid":"https://pubmed.ncbi.nlm.nih.gov/11948602"},"language":"en","primary_location":{"id":"doi:10.1002/lsm.10040","doi":"https://doi.org/10.1002/lsm.10040","is_oa":false,"landing_page_url":"https://doi.org/10.1002/lsm.10040","pdf_url":null,"source":{"id":"https://openalex.org/S155721155","display_name":"Lasers in Surgery and Medicine","issn_l":"0196-8092","issn":["0196-8092","1096-9101"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lasers in Surgery and Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051493247","display_name":"Arnold DC Rivera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arnold DC Rivera","raw_affiliation_strings":["Department of Urology, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103565785","display_name":"C. Noojin Walker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles N. Walker","raw_affiliation_strings":["Department of Urology, Center for Pediatric Urology and Laboratory for Minimally Invasive Urologic Surgery, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Center for Pediatric Urology and Laboratory for Minimally Invasive Urologic Surgery, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051932074","display_name":"Clifford B. Bleustein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Clifford Bleustein","raw_affiliation_strings":["Department of Urology, Center for Pediatric Urology and Laboratory for Minimally Invasive Urologic Surgery, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Center for Pediatric Urology and Laboratory for Minimally Invasive Urologic Surgery, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015246203","display_name":"Benjamin Choi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Choi","raw_affiliation_strings":["Department of Urology, Center for Pediatric Urology and Laboratory for Minimally Invasive Urologic Surgery, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Center for Pediatric Urology and Laboratory for Minimally Invasive Urologic Surgery, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090886190","display_name":"Dix Phillip Poppas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dix P. Poppas","raw_affiliation_strings":["Department of Urology, Center for Pediatric Urology and Laboratory for Minimally Invasive Urologic Surgery, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Center for Pediatric Urology and Laboratory for Minimally Invasive Urologic Surgery, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068682755","display_name":"Diane Felsen","orcid":"https://orcid.org/0000-0003-1190-9626","observed_orcids":["https://orcid.org/0000-0003-1190-9626"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Diane Felsen","raw_affiliation_strings":["Department of Urology, Center for Pediatric Urology and Laboratory for Minimally Invasive Urologic Surgery, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021","Department of Urology, Weill Medical College of Cornell University, 1300 York Avenue, Box 94, New York, NY 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Center for Pediatric Urology and Laboratory for Minimally Invasive Urologic Surgery, The Children's Hospital of New York, Weill Medical College of Cornell University, New York, New York 10021","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Department of Urology, Weill Medical College of Cornell University, 1300 York Avenue, Box 94, New York, NY 10021","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5068682755"],"corresponding_institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"],"apc_list":{"value":4620,"currency":"USD","value_usd":4620},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.1775024,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"30","issue":"4","first_page":"313","last_page":"319"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.8690999746322632,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.8690999746322632,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.09380000084638596,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12906","display_name":"Surgical Sutures and Adhesives","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adenovirus-vectors","display_name":"adenoviral vector","score":0.9449999928474426},{"id":"https://openalex.org/keywords/gene-transfer","display_name":"gene transfer","score":0.8370000123977661},{"id":"https://openalex.org/keywords/beta-galactosidase","display_name":"beta-galactosidase","score":0.9259999990463257},{"id":"https://openalex.org/keywords/laser-tissue-welding","display_name":"laser tissue welding","score":0.8610000014305115},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.6869999766349792},{"id":"https://openalex.org/keywords/cytokine-gene-therapy","display_name":"cytokine gene therapy","score":0.6890000104904175},{"id":"https://openalex.org/keywords/3t3-cells","display_name":"3T3 fibroblasts","score":0.8960000276565552}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.7586817741394043},{"id":"https://openalex.org/C32470452","wikidata":"https://www.wikidata.org/wiki/Q2298489","display_name":"Viral vector","level":4,"score":0.7045990228652954},{"id":"https://openalex.org/C111599444","wikidata":"https://www.wikidata.org/wiki/Q213901","display_name":"Genetic enhancement","level":3,"score":0.6751121282577515},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.6749832630157471},{"id":"https://openalex.org/C15152581","wikidata":"https://www.wikidata.org/wiki/Q7833966","display_name":"Transduction (biophysics)","level":2,"score":0.6013652086257935},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5932148694992065},{"id":"https://openalex.org/C2776954459","wikidata":"https://www.wikidata.org/wiki/Q193447","display_name":"Adenoviridae","level":4,"score":0.5120308995246887},{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.4621022939682007},{"id":"https://openalex.org/C3018928802","wikidata":"https://www.wikidata.org/wiki/Q83185","display_name":"Gene transfer","level":3,"score":0.41351163387298584},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3938150107860565},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38849183917045593},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30316296219825745},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2778373658657074},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2162112593650818},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08820918202400208},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.05557727813720703},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000256","descriptor_name":"Adenoviridae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001616","descriptor_name":"beta-Galactosidase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001616","descriptor_name":"beta-Galactosidase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007834","descriptor_name":"Lasers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016475","descriptor_name":"3T3 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/lsm.10040","doi":"https://doi.org/10.1002/lsm.10040","is_oa":false,"landing_page_url":"https://doi.org/10.1002/lsm.10040","pdf_url":null,"source":{"id":"https://openalex.org/S155721155","display_name":"Lasers in Surgery and Medicine","issn_l":"0196-8092","issn":["0196-8092","1096-9101"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lasers in Surgery and Medicine","raw_type":"journal-article"},{"id":"pmid:11948602","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11948602","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lasers in surgery and medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1559702139","https://openalex.org/W1822447409","https://openalex.org/W1963963041","https://openalex.org/W1968528332","https://openalex.org/W2001297140","https://openalex.org/W2006191739","https://openalex.org/W2007903872","https://openalex.org/W2011214284","https://openalex.org/W2013909807","https://openalex.org/W2015776844","https://openalex.org/W2017237256","https://openalex.org/W2029347064","https://openalex.org/W2032667836","https://openalex.org/W2032678451","https://openalex.org/W2047999579","https://openalex.org/W2054084083","https://openalex.org/W2063209485","https://openalex.org/W2065848728","https://openalex.org/W2072847918","https://openalex.org/W2081583807","https://openalex.org/W2082311983","https://openalex.org/W2101807707","https://openalex.org/W2105509434","https://openalex.org/W2320869084","https://openalex.org/W2325727928","https://openalex.org/W2408776107"],"related_works":["https://openalex.org/W2065848728","https://openalex.org/W2154803067","https://openalex.org/W2182190915","https://openalex.org/W1971884237","https://openalex.org/W1995496186","https://openalex.org/W2082311983","https://openalex.org/W1977468422","https://openalex.org/W2044161339","https://openalex.org/W1987443183","https://openalex.org/W2229427516"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1,65],"OBJECTIVE:":[2],"Laser":[3],"tissue":[4],"welding":[5],"with":[6],"human":[7],"albumin":[8],"solder":[9],"(HAS)":[10],"has":[11],"been":[12,24],"used":[13,25,70,109],"as":[14],"an":[15],"alternative":[16],"method":[17],"of":[18,47,53,75,85,103,119],"wound":[19,35,104,155],"closure.":[20,36],"Adenoviral":[21],"vectors":[22,148],"have":[23],"to":[26,33,71,149],"introduce":[27],"various":[28],"cytokine":[29,151],"genes":[30,152],"into":[31],"wounds":[32],"accelerate":[34],"In":[37],"the":[38,45,54,73,117,125],"present":[39],"study,":[40],"we":[41],"were":[42,69],"interested":[43],"in":[44,58,61,81,106,111,138,141,153],"effect":[46,74],"HAS":[48,76,115,130,144],"on":[49,77],"adenoviral":[50,147],"vector":[51],"transfer":[52,80],"beta-galactosidase":[55],"(beta-gal)":[56],"gene":[57,79],"vitro":[59,139],"and":[60,92,123,140],"vivo.":[62,142],"STUDY":[63],"DESIGN/MATERIALS":[64],"METHODS:":[66],"3T3":[67],"fibroblasts":[68],"study":[72],"beta-gal":[78,86,121],"vitro.":[82],"The":[83],"presence":[84],"was":[87,108],"determined":[88],"by":[89,95,135],"Western":[90],"blot,":[91],"its":[93],"activity":[94],"a":[96],"colorimetric":[97],"assay.":[98],"A":[99],"punch":[100],"biopsy":[101],"model":[102],"healing":[105,156],"pigs":[107],"for":[110],"vivo":[112],"experiments.":[113,157],"RESULTS:":[114],"increased":[116],"efficiency":[118],"adenoviral-mediated":[120],"transduction":[122],"stabilized":[124],"adenovirus":[126,132],"at":[127],"room":[128],"temperature.":[129],"protected":[131],"from":[133],"inactivation":[134],"laser,":[136],"both":[137],"CONCLUSIONS:":[143],"may":[145],"stabilize":[146],"deliver":[150],"future":[154]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}