{"id":"https://openalex.org/W2145237639","doi":"https://doi.org/10.1117/12.806497","title":"Photoacoustic molecular imaging using single walled carbon nanotubes in living mice","display_name":"Photoacoustic molecular imaging using single walled carbon nanotubes in living mice","publication_year":2009,"publication_date":"2009-02-12","ids":{"openalex":"https://openalex.org/W2145237639","doi":"https://doi.org/10.1117/12.806497","mag":"2145237639"},"language":"en","primary_location":{"id":"doi:10.1117/12.806497","doi":"https://doi.org/10.1117/12.806497","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.806497","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030652147","display_name":"Adam de la Zerda","orcid":"https://orcid.org/0000-0002-5617-0194","observed_orcids":["https://orcid.org/0000-0002-5617-0194"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam de la Zerda","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079656498","display_name":"Cristina L. Zavaleta","orcid":"https://orcid.org/0000-0001-7314-2446","observed_orcids":["https://orcid.org/0000-0001-7314-2446"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cristina Zavaleta","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047820662","display_name":"Shay Keren","orcid":"https://orcid.org/0000-0002-7891-2478","observed_orcids":["https://orcid.org/0000-0002-7891-2478"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shay Keren","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110453516","display_name":"Srikant Vaithilingam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Srikant Vaithilingam","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039812828","display_name":"Sunil Bodapati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sunil Bodapati","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002356706","display_name":"Robert Teed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Teed","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100452094","display_name":"Zhuang Liu","orcid":"https://orcid.org/0000-0002-1629-1039","observed_orcids":["https://orcid.org/0000-0002-1629-1039"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhuang Liu","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061338137","display_name":"Jelena Levi","orcid":"https://orcid.org/0000-0002-0846-0795","observed_orcids":["https://orcid.org/0000-0002-0846-0795"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jelena Levi","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063316602","display_name":"Bryan Ronain Smith","orcid":"https://orcid.org/0000-0002-5990-2901","observed_orcids":["https://orcid.org/0000-0002-5990-2901","https://orcid.org/0000-0001-9850-5944"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bryan R. Smith","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110209943","display_name":"Te-Jen Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Te-Jen Ma","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009868880","display_name":"\u00d6mer Oralkan","orcid":"https://orcid.org/0000-0001-8616-6877","observed_orcids":["https://orcid.org/0000-0001-8616-6877"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omer Oralkan","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075963891","display_name":"Zhen Cheng","orcid":"https://orcid.org/0000-0001-8177-9463","observed_orcids":["https://orcid.org/0000-0001-8177-9463"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhen Cheng","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100636551","display_name":"Xiaoyuan Shawn Chen","orcid":"https://orcid.org/0000-0002-9622-0870","observed_orcids":["https://orcid.org/0000-0002-9622-0870"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaoyuan Chen","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102781933","display_name":"Hongjie Dai","orcid":"https://orcid.org/0000-0002-4906-4502","observed_orcids":["https://orcid.org/0000-0002-4906-4502","https://orcid.org/0000-0003-3239-0835","https://orcid.org/0000-0002-8541-5752"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hongjie Dai","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049840465","display_name":"Butrus T. Khuri-Yakub","orcid":"https://orcid.org/0000-0003-3940-7898","observed_orcids":["https://orcid.org/0000-0003-3940-7898","https://orcid.org/0000-0001-5299-8018"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Butrus T. Khuri-Yakub","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019955301","display_name":"Sanjiv Sam Gambhir","orcid":"https://orcid.org/0000-0002-2711-7554","observed_orcids":["https://orcid.org/0000-0002-2711-7554"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sanjiv S. Gambhir","raw_affiliation_strings":["Stanford Univ. (United States)","Stanford University (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Univ. (United States)","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University (United States)","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I97018004"],"apc_list":null,"apc_paid":null,"fwci":0.6947,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.71817279,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"7177","issue":null,"first_page":"717725","last_page":"717725"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.02800000086426735,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/single-walled-carbon-nanotubes","display_name":"single-walled carbon nanotubes","score":0.9399999976158142},{"id":"https://openalex.org/keywords/rgd-peptide","display_name":"RGD peptide","score":0.7889999747276306},{"id":"https://openalex.org/keywords/alpha-v-beta3-integrin","display_name":"alpha v beta 3 integrin","score":0.7710000276565552},{"id":"https://openalex.org/keywords/tumor-angiogenesis","display_name":"tumor angiogenesis","score":0.859000027179718},{"id":"https://openalex.org/keywords/targeted-imaging-agents","display_name":"targeted imaging agents","score":0.8640000224113464},{"id":"https://openalex.org/keywords/tumor-xenografts","display_name":"tumor xenografts","score":0.9079999923706055},{"id":"https://openalex.org/keywords/u87-cells","display_name":"U87 cells","score":0.8360000252723694},{"id":"https://openalex.org/keywords/polyethylene-glycol-conjugation","display_name":"polyethylene glycol conjugation","score":0.7760000228881836},{"id":"https://openalex.org/keywords/micro-raman-spectroscopy","display_name":"micro-Raman spectroscopy","score":0.6079999804496765}],"concepts":[{"id":"https://openalex.org/C513720949","wikidata":"https://www.wikidata.org/wiki/Q1778729","display_name":"Carbon nanotube","level":2,"score":0.6865500211715698},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6691344976425171},{"id":"https://openalex.org/C54932901","wikidata":"https://www.wikidata.org/wiki/Q7187705","display_name":"Photoacoustic imaging in biomedicine","level":2,"score":0.6138018369674683},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5890322923660278},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.47198373079299927},{"id":"https://openalex.org/C136339569","wikidata":"https://www.wikidata.org/wiki/Q1142297","display_name":"Molecular imaging","level":3,"score":0.45477980375289917},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4370718002319336},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4118339419364929},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.32656121253967285},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.2470138967037201},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.24600812792778015},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2081119418144226},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09898346662521362},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.08279240131378174},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08001554012298584},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.806497","doi":"https://doi.org/10.1117/12.806497","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.806497","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1964433907","https://openalex.org/W1964868194","https://openalex.org/W1971397050","https://openalex.org/W1982053913","https://openalex.org/W1995583204","https://openalex.org/W2009680704","https://openalex.org/W2013847097","https://openalex.org/W2023074414","https://openalex.org/W2025244200","https://openalex.org/W2036926656","https://openalex.org/W2052277207","https://openalex.org/W2052570048","https://openalex.org/W2054124980","https://openalex.org/W2065826341","https://openalex.org/W2068003824","https://openalex.org/W2083793124","https://openalex.org/W2089901886","https://openalex.org/W2104979069","https://openalex.org/W2110856667","https://openalex.org/W2135856533","https://openalex.org/W2137215170","https://openalex.org/W2156038372","https://openalex.org/W2158211485","https://openalex.org/W2158968888","https://openalex.org/W2161105252","https://openalex.org/W2171221778","https://openalex.org/W4237878273"],"related_works":["https://openalex.org/W4254128848","https://openalex.org/W4301851731","https://openalex.org/W1966138469","https://openalex.org/W2096952219","https://openalex.org/W2079448771","https://openalex.org/W2128537375","https://openalex.org/W2012534987","https://openalex.org/W840256443","https://openalex.org/W2081328197","https://openalex.org/W2120287782"],"abstract_inverted_index":{"Photoacoustic":[0],"molecular":[1,14],"imaging":[2,11,22,41],"is":[3,65,243],"an":[4],"emerging":[5],"technology":[6],"offering":[7],"non-invasive":[8],"high":[9],"resolution":[10],"of":[12,16,33,76,93,151,167,214],"the":[13,28,31,61,73,77,102,106,147,185,197,200,246],"expressions":[15],"a":[17,20,239],"disease":[18],"using":[19,238],"photoacoustic":[21,74,91,134,224],"agent.":[23],"Here":[24],"we":[25,71,145,178],"demonstrate":[26],"for":[27,121,192],"first":[29],"time":[30],"utility":[32],"single":[34],"walled":[35],"carbon":[36],"nanotubes":[37],"(SWNTs)":[38],"as":[39],"targeted":[40],"agents":[42],"in":[43,153,169],"living":[44,154,170],"mice":[45,155,171,190,215,228],"bearing":[46],"tumor":[47,68,201],"xenografts.":[48],"SWNTs":[49,94,107,130,138,152,159,168,183,219,247],"were":[50,235],"conjugated":[51],"with":[52,67,116,141,217,227,230],"polyethylene-glycol-5000":[53],"connected":[54],"to":[55,59,98,105,112,174,187,205,245],"Arg-Gly-Asp":[56],"(RGD)":[57],"peptide":[58],"target":[60],"\u03b1v\u03b23":[62],"integrin":[63],"that":[64,128,242],"associated":[66],"angiogenesis.":[69],"In-vitro,":[70],"characterized":[72],"spectra":[75],"particles,":[78],"their":[79,84],"signal":[80,92,135,198,225],"linearity":[81],"and":[82,108,181,195,203],"tested":[83],"uptake":[85,125],"by":[86,101,156],"\u03b1v\u03b23-expressing":[87],"cells":[88],"(U87MG).":[89],"The":[90,123,163],"was":[95,109,172],"found":[96,111,173],"not":[97],"be":[99,113,175],"affected":[100],"RGD":[103],"conjugation":[104],"also":[110],"highly":[114],"linear":[115],"concentration":[117,150,166],"(R2":[118],"=":[119],"0.9997":[120],"25-400nM).":[122],"cell":[124],"studies":[126],"showed":[127,220],"RGD-targeted":[129,218],"gave":[131],"75%":[132],"higher":[133,223],"than":[136],"non-targeted":[137,182,231],"when":[139],"incubated":[140],"U87MG":[142,188],"cells.":[143],"In-vivo,":[144],"measured":[146,196],"minimal":[148],"detectable":[149,165],"subcutaneously":[157],"injecting":[158],"at":[160],"increasing":[161],"concentrations.":[162],"lowest":[164],"50nM.":[176],"Finally,":[177],"administered":[179],"RGDtargeted":[180],"via":[184],"tail-vein":[186],"tumor-bearing":[189],"(n=4":[191],"each":[193],"group)":[194],"from":[199],"before":[202],"up":[204],"4":[206,210],"hours":[207,211],"post-injection.":[208],"At":[209],"post-injection,":[212],"tumors":[213],"injected":[216,229],"8":[221],"times":[222],"compared":[226],"SWNTs.":[232],"These":[233],"results":[234],"verified":[236],"ex-vivo":[237],"Raman":[240,248],"microscope":[241],"sensitive":[244],"signal.":[249]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2016-06-24T00:00:00"}