{"id":"https://openalex.org/W2145004264","doi":"https://doi.org/10.2337/dc10-1405","title":"Better Glycemic Control Is Associated With Maintenance of Lower-Extremity Function Over Time in Mexican American and European American Older Adults With Diabetes","display_name":"Better Glycemic Control Is Associated With Maintenance of Lower-Extremity Function Over Time in Mexican American and European American Older Adults With Diabetes","publication_year":2011,"publication_date":"2011-01-08","ids":{"openalex":"https://openalex.org/W2145004264","doi":"https://doi.org/10.2337/dc10-1405","mag":"2145004264","pmid":"https://pubmed.ncbi.nlm.nih.gov/21216857","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3024332"},"language":"en","primary_location":{"id":"doi:10.2337/dc10-1405","doi":"https://doi.org/10.2337/dc10-1405","is_oa":true,"landing_page_url":"https://doi.org/10.2337/dc10-1405","pdf_url":"https://diabetesjournals.org/care/article-pdf/34/2/268/607921/268.pdf","source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://diabetesjournals.org/care/article-pdf/34/2/268/607921/268.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110164930","display_name":"Chen-Pin Wang","orcid":"https://orcid.org/0000-0002-1670-2838","observed_orcids":["https://orcid.org/0000-0002-1670-2838"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chen-Pin Wang","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006356455","display_name":"Helen P. Hazuda","orcid":"https://orcid.org/0000-0002-7313-4160","observed_orcids":["https://orcid.org/0000-0002-7313-4160"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]},{"id":"https://openalex.org/I2802109968","display_name":"Audie L. Murphy Memorial VA Hospital","ror":"https://ror.org/035xhk118","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2802109968","https://openalex.org/I4210144023","https://openalex.org/I4210144081"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Helen P. Hazuda","raw_affiliation_strings":["Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas","Supervisory Research Health Scientist, Research Service, Department of Veterans Affairs, Audie Murphy Medical Center, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Supervisory Research Health Scientist, Research Service, Department of Veterans Affairs, Audie Murphy Medical Center, San Antonio, Texas","institution_ids":["https://openalex.org/I2802109968"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5006356455"],"corresponding_institution_ids":["https://openalex.org/I165951966","https://openalex.org/I2802109968"],"apc_list":null,"apc_paid":null,"fwci":3.3769,"has_fulltext":true,"cited_by_count":45,"citation_normalized_percentile":{"value":0.92378119,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"34","issue":"2","first_page":"268","last_page":"273"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.3449999988079071,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.3449999988079071,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.19779999554157257,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10793","display_name":"Diabetes Management and Education","score":0.0608999989926815,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.9950000047683716},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.8939999938011169},{"id":"https://openalex.org/keywords/lower-limb-function","display_name":"lower limb function","score":0.9589999914169312},{"id":"https://openalex.org/keywords/older-adults-with-diabetes","display_name":"diabetes in older adults","score":0.7549999952316284},{"id":"https://openalex.org/keywords/functional-decline","display_name":"functional decline","score":0.9470000267028809},{"id":"https://openalex.org/keywords/mexican-americans","display_name":"Mexican Americans","score":0.4580000042915344},{"id":"https://openalex.org/keywords/european-americans","display_name":"European Americans","score":0.9829999804496765},{"id":"https://openalex.org/keywords/short-physical-performance-battery","display_name":"Short Physical Performance Battery","score":0.7490000128746033},{"id":"https://openalex.org/keywords/intra-individual-variability","display_name":"within-person variability","score":0.6510000228881836}],"concepts":[{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.9210690259933472},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8468354344367981},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.618507981300354},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.484840989112854},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.4666096568107605},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.381692111492157},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0712403655052185}],"mesh":[{"descriptor_ui":"D000203","descriptor_name":"Activities of Daily Living","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004185","descriptor_name":"Disability Evaluation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006943","descriptor_name":"Hyperglycemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006943","descriptor_name":"Hyperglycemia","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D007866","descriptor_name":"Leg","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017058","descriptor_name":"Mexican Americans","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D048909","descriptor_name":"Diabetes Complications","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D048909","descriptor_name":"Diabetes Complications","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D051346","descriptor_name":"Mobility Limitation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.2337/dc10-1405","doi":"https://doi.org/10.2337/dc10-1405","is_oa":true,"landing_page_url":"https://doi.org/10.2337/dc10-1405","pdf_url":"https://diabetesjournals.org/care/article-pdf/34/2/268/607921/268.pdf","source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2274012","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3024332","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3024332","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3024332","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"Text"},{"id":"pmid:21216857","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21216857","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes care","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.2337/dc10-1405","doi":"https://doi.org/10.2337/dc10-1405","is_oa":true,"landing_page_url":"https://doi.org/10.2337/dc10-1405","pdf_url":"https://diabetesjournals.org/care/article-pdf/34/2/268/607921/268.pdf","source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G3548634124","display_name":"GENERAL CLINICAL RESEARCH CENTER","funder_award_id":"M01RR001346","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G631364279","display_name":"SAN ANTONIO LONGITUDINAL STUDY OF AGING","funder_award_id":"R01AG010444","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G7528724491","display_name":"DISABLEMENT IN AN AGING BI-ETHNIC COHORT","funder_award_id":"R01AG016518","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G8500325512","display_name":"Heterogeneity, Glycemic Control & Macro-Vascular Complications in Type 2 Diabetes","funder_award_id":"K25DK075092","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320333877","display_name":"Cereal Partners Worldwide","ror":"https://ror.org/04d8ew893"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2145004264.pdf","grobid_xml":"https://content.openalex.org/works/W2145004264.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1482694899","https://openalex.org/W1505278203","https://openalex.org/W1940571819","https://openalex.org/W2002793458","https://openalex.org/W2013698955","https://openalex.org/W2039555228","https://openalex.org/W2044311614","https://openalex.org/W2079257116","https://openalex.org/W2086941566","https://openalex.org/W2094323726","https://openalex.org/W2096657471","https://openalex.org/W2096667822","https://openalex.org/W2099054627","https://openalex.org/W2105400393","https://openalex.org/W2123946565","https://openalex.org/W2135881062","https://openalex.org/W2140937253","https://openalex.org/W2145622148","https://openalex.org/W2156121263","https://openalex.org/W2170843410","https://openalex.org/W2171294019","https://openalex.org/W2253827616","https://openalex.org/W2345903479","https://openalex.org/W2414167269","https://openalex.org/W3022929210","https://openalex.org/W3126800207","https://openalex.org/W4234393699"],"related_works":["https://openalex.org/W7095518471","https://openalex.org/W2098986107","https://openalex.org/W2906216446","https://openalex.org/W1809283700","https://openalex.org/W2138554092","https://openalex.org/W1970022715","https://openalex.org/W7166666106","https://openalex.org/W2033847597","https://openalex.org/W4393091710","https://openalex.org/W1966338694"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Diabetes":[1,63],"is":[2,27],"a":[3,70,140,156],"major":[4],"cause":[5],"of":[6,15,32,56,75,85,123,174,225],"functional":[7],"decline":[8],"among":[9],"older":[10,38,211],"adults,":[11],"but":[12],"the":[13,51,94,179,182,189,199,205],"role":[14],"glycemic":[16,25,110,135,216],"control":[17,26,111,136,142,158,201,207,217],"remains":[18],"unclear.":[19],"This":[20],"article":[21],"assesses":[22],"whether":[23],"better":[24,30,157,200,215],"associated":[28],"with":[29,40,144,160,213],"maintenance":[31,173,224],"lower-extremity":[33,86,124,175,226],"function":[34,87,125],"over":[35,69],"time":[36],"in":[37,50,153,198,204],"adults":[39,212],"diabetes.":[41],"RESEARCH":[42],"DESIGN":[43],"AND":[44],"METHODS:":[45],"Participants":[46],"(n":[47],"=":[48],"119)":[49],"San":[52],"Antonio":[53],"Longitudinal":[54],"Study":[55],"Aging,":[57],"ages":[58],"71-85,":[59],"who":[60],"met":[61],"American":[62],"Association":[64],"diabetes":[65],"criteria":[66],"were":[67,78,88,138,195],"followed":[68],"36-month":[71],"period.":[72],"Seven":[73],"measures":[74,84,187],"A1C":[76],"(HbA(1c))":[77],"obtained":[79,89],"at":[80,90],"6-month":[81],"intervals;":[82],"three":[83],"18-month":[91],"intervals":[92],"using":[93,113,130],"Short":[95],"Physical":[96],"Performance":[97],"Battery":[98],"(SPPB).":[99],"A":[100],"two-step":[101],"analytic":[102],"approach":[103],"was":[104],"used,":[105],"first,":[106],"to":[107,120],"identify":[108],"distinct":[109],"classes":[112,129,137],"latent":[114],"growth":[115],"mixture":[116],"modeling":[117],"and,":[118],"second,":[119],"examine":[121],"trajectories":[122],"based":[126],"on":[127],"these":[128],"path":[131],"analysis.":[132],"RESULTS:":[133],"Two":[134],"identified:":[139],"poorer":[141,206],"class":[143,159,202],"higher":[145,150],"means":[146,162],"(all":[147,163],">7%)":[148],"and":[149,155,165,171,184,188,191,222],"within-subject":[151,167],"variability":[152],"HbA(1c)":[154],"lower":[161,166],"<7%)":[164],"variability.":[168],"The":[169],"short-term":[170,221],"long-term":[172,223],"function,":[176],"assessed":[177],"by":[178],"association":[180],"between":[181],"first":[183,190],"second":[185],"SPPB":[186,193],"third":[192],"measures,":[194],"both":[196,220],"greater":[197],"than":[203],"class.":[208],"CONCLUSIONS:":[209],"Among":[210],"diabetes,":[214],"may":[218],"improve":[219],"function.":[227]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}