{"id":"https://openalex.org/W2144635144","doi":"https://doi.org/10.1186/1743-8977-6-30","title":"Toxic effects of brake wear particles on epithelial lung cells in vitro","display_name":"Toxic effects of brake wear particles on epithelial lung cells in vitro","publication_year":2009,"publication_date":"2009-11-20","ids":{"openalex":"https://openalex.org/W2144635144","doi":"https://doi.org/10.1186/1743-8977-6-30","mag":"2144635144","pmid":"https://pubmed.ncbi.nlm.nih.gov/19930544","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2784745"},"language":"en","primary_location":{"id":"doi:10.1186/1743-8977-6-30","doi":"https://doi.org/10.1186/1743-8977-6-30","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1743-8977-6-30","pdf_url":"https://particleandfibretoxicology.biomedcentral.com/counter/pdf/10.1186/1743-8977-6-30","source":{"id":"https://openalex.org/S189275214","display_name":"Particle and Fibre Toxicology","issn_l":"1743-8977","issn":["1743-8977"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Particle and Fibre Toxicology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://particleandfibretoxicology.biomedcentral.com/counter/pdf/10.1186/1743-8977-6-30","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114832723","display_name":"Michael Gasser","orcid":"https://orcid.org/0000-0001-6452-3220","observed_orcids":["https://orcid.org/0000-0001-6452-3220"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Michael Gasser","raw_affiliation_strings":["Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland. rothen@ana.unibe.ch","Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland. rothen@ana.unibe.ch","institution_ids":["https://openalex.org/I118564535"]},{"raw_affiliation_string":"Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058079643","display_name":"Michael Riediker","orcid":"https://orcid.org/0000-0002-5268-864X","observed_orcids":["https://orcid.org/0000-0002-5268-864X"]},"institutions":[{"id":"https://openalex.org/I2252230247","display_name":"Institute for Work and Health","ror":"https://ror.org/02rycsd19","country_code":"CH","type":"facility","lineage":["https://openalex.org/I2252230247","https://openalex.org/I4210149340"]},{"id":"https://openalex.org/I97565354","display_name":"University of Lausanne","ror":"https://ror.org/019whta54","country_code":"CH","type":"education","lineage":["https://openalex.org/I97565354"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Michael Riediker","raw_affiliation_strings":["Institute for Work and Health, University of Lausanne and Geneva, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Work and Health, University of Lausanne and Geneva, Lausanne, Switzerland","institution_ids":["https://openalex.org/I2252230247","https://openalex.org/I97565354"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Loretta Mueller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Loretta Mueller","raw_affiliation_strings":["Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059633407","display_name":"Alain Perrenoud","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]},{"id":"https://openalex.org/I2252230247","display_name":"Institute for Work and Health","ror":"https://ror.org/02rycsd19","country_code":"CH","type":"facility","lineage":["https://openalex.org/I2252230247","https://openalex.org/I4210149340"]},{"id":"https://openalex.org/I97565354","display_name":"University of Lausanne","ror":"https://ror.org/019whta54","country_code":"CH","type":"education","lineage":["https://openalex.org/I97565354"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Alain Perrenoud","raw_affiliation_strings":["Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland","Institute for Work and Health, University of Lausanne and Geneva, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535"]},{"raw_affiliation_string":"Institute for Work and Health, University of Lausanne and Geneva, Lausanne, Switzerland","institution_ids":["https://openalex.org/I2252230247","https://openalex.org/I97565354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002132214","display_name":"Fabian Blank","orcid":"https://orcid.org/0000-0002-3374-0414","observed_orcids":["https://orcid.org/0000-0002-3374-0414"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Fabian Blank","raw_affiliation_strings":["Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109328022","display_name":"Peter Gehr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Peter Gehr","raw_affiliation_strings":["Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085869019","display_name":"Barbara Rothen\u2010Rutishauser","orcid":"https://orcid.org/0000-0002-7805-9366","observed_orcids":["https://orcid.org/0000-0002-7805-9366"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Barbara Rothen-Rutishauser","raw_affiliation_strings":["Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Anatomy, Division of Histology, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5085869019"],"corresponding_institution_ids":["https://openalex.org/I118564535"],"apc_list":{"value":4090,"currency":"USD","value_usd":4090},"apc_paid":{"value":4090,"currency":"USD","value_usd":4090},"fwci":4.735,"has_fulltext":true,"cited_by_count":195,"citation_normalized_percentile":{"value":0.94979403,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"6","issue":"1","first_page":"30","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12197","display_name":"Brake Systems and Friction Analysis","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/2203","display_name":"Automotive Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brake-wear-particles","display_name":"brake wear particles","score":1.0},{"id":"https://openalex.org/keywords/traffic-related-particulate-matter","display_name":"traffic-related particulate matter","score":0.847000002861023},{"id":"https://openalex.org/keywords/lung-epithelial-cells","display_name":"lung epithelial cells","score":0.8920000195503235},{"id":"https://openalex.org/keywords/tight-junctions","display_name":"tight junctions","score":0.8700000047683716},{"id":"https://openalex.org/keywords/occludin","display_name":"occludin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9670000076293945},{"id":"https://openalex.org/keywords/interleukin-8","display_name":"interleukin-8","score":0.9200000166893005},{"id":"https://openalex.org/keywords/proinflammatory-response","display_name":"pro-inflammatory response","score":0.8299999833106995},{"id":"https://openalex.org/keywords/metal-emissions","display_name":"metal emissions","score":0.5049999952316284},{"id":"https://openalex.org/keywords/iron","display_name":"iron","score":0.6010000109672546},{"id":"https://openalex.org/keywords/copper","display_name":"copper","score":0.9890000224113464},{"id":"https://openalex.org/keywords/manganese","display_name":"manganese","score":1.0},{"id":"https://openalex.org/keywords/organic-carbon","display_name":"organic carbon","score":0.9750000238418579},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8569999933242798},{"id":"https://openalex.org/keywords/air-liquid-interface","display_name":"air-liquid interface","score":0.8230000138282776}],"concepts":[{"id":"https://openalex.org/C2775962179","wikidata":"https://www.wikidata.org/wiki/Q2013337","display_name":"Occludin","level":3,"score":0.9014976024627686},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.6012279987335205},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.586082398891449},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5451962947845459},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5200961828231812},{"id":"https://openalex.org/C177779419","wikidata":"https://www.wikidata.org/wiki/Q1053832","display_name":"Tight junction","level":2,"score":0.48417049646377563},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3983518183231354},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26093733310699463},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19838973879814148}],"mesh":[],"locations_count":9,"locations":[{"id":"doi:10.1186/1743-8977-6-30","doi":"https://doi.org/10.1186/1743-8977-6-30","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1743-8977-6-30","pdf_url":"https://particleandfibretoxicology.biomedcentral.com/counter/pdf/10.1186/1743-8977-6-30","source":{"id":"https://openalex.org/S189275214","display_name":"Particle and Fibre Toxicology","issn_l":"1743-8977","issn":["1743-8977"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Particle and Fibre Toxicology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2784745","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2784745","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Part Fibre Toxicol","raw_type":"Text"},{"id":"pmid:19930544","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19930544","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Particle and fibre toxicology","raw_type":"Journal Article"},{"id":"pmh:oai:serval.unil.ch:BIB_834D29655A82","doi":null,"is_oa":true,"landing_page_url":"https://serval.unil.ch/notice/serval:BIB_834D29655A82","pdf_url":null,"source":{"id":"https://openalex.org/S4306401797","display_name":"SERVAL (Universit\u00e9 de Lausanne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210093590","host_organization_name":"Swiss School of Archaeology in Greece","host_organization_lineage":["https://openalex.org/I4210093590"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Particle and Fibre Toxicology, vol. 6, no. 30, pp. [13]","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unil.ch:iris/170466","doi":null,"is_oa":true,"landing_page_url":"https://iris.unil.ch/handle/iris/170466","pdf_url":"https://iris.unil.ch/bitstreams/e3ea243c-39f0-437a-9461-6efe275f8b7b/download","source":{"id":"https://openalex.org/S7407055444","display_name":"IRIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:doi:10.7892/boris.31078","doi":null,"is_oa":false,"landing_page_url":"https://boris-portal.unibe.ch/handle/20.500.12422/104546","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"pmh:oai:boris.unibe.ch:31078","doi":null,"is_oa":true,"landing_page_url":"https://boris.unibe.ch/31078/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401086","display_name":"Bern Open Repository and Information System (University of Bern)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I118564535","host_organization_name":"University of Bern","host_organization_lineage":["https://openalex.org/I118564535"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Gasser, Michael; Riediker, Michael; Mueller, Loretta; Perrenoud, Alain; Blank, Fabian; Gehr, Peter; Rothen-Rutishauser, Barbara (2009). Toxic effects of brake wear particles on epithelial lung cells in vitro. Particle and fibre toxicology, 6, p. 30. London: BioMed Central 10.1186/1743-8977-6-30 &lt;http://dx.doi.org/10.1186/1743-8977-6-30&gt;","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:c2e444a090624af19cf1493f9f1c830e","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/c2e444a090624af19cf1493f9f1c830e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Particle and Fibre Toxicology, Vol 6, Iss 1, p 30 (2009)","raw_type":"article"},{"id":"doi:10.7892/boris.31078","doi":"https://doi.org/10.7892/boris.31078","is_oa":true,"landing_page_url":"https://doi.org/10.7892/boris.31078","pdf_url":null,"source":{"id":"https://openalex.org/S7407053152","display_name":"Open Access CRIS of the University of Bern","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1186/1743-8977-6-30","doi":"https://doi.org/10.1186/1743-8977-6-30","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1743-8977-6-30","pdf_url":"https://particleandfibretoxicology.biomedcentral.com/counter/pdf/10.1186/1743-8977-6-30","source":{"id":"https://openalex.org/S189275214","display_name":"Particle and Fibre Toxicology","issn_l":"1743-8977","issn":["1743-8977"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Particle and Fibre Toxicology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321652","display_name":"Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich","ror":"https://ror.org/05a28rw58"},{"id":"https://openalex.org/F4320334856","display_name":"Bundesamt f\u00fcr Umwelt","ror":"https://ror.org/04t48sm91"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2144635144.pdf","grobid_xml":"https://content.openalex.org/works/W2144635144.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W218984710","https://openalex.org/W1489018618","https://openalex.org/W1495194589","https://openalex.org/W1981032069","https://openalex.org/W1988043397","https://openalex.org/W1990998953","https://openalex.org/W1997158320","https://openalex.org/W1998862863","https://openalex.org/W2008019615","https://openalex.org/W2012427295","https://openalex.org/W2015272708","https://openalex.org/W2024302469","https://openalex.org/W2029636116","https://openalex.org/W2040066643","https://openalex.org/W2040226008","https://openalex.org/W2040694220","https://openalex.org/W2044525398","https://openalex.org/W2046080620","https://openalex.org/W2047806545","https://openalex.org/W2059944938","https://openalex.org/W2064221754","https://openalex.org/W2073912316","https://openalex.org/W2075211725","https://openalex.org/W2086060074","https://openalex.org/W2089716915","https://openalex.org/W2095343487","https://openalex.org/W2100750710","https://openalex.org/W2103449823","https://openalex.org/W2104198157","https://openalex.org/W2113738790","https://openalex.org/W2117326659","https://openalex.org/W2127456551","https://openalex.org/W2129689267","https://openalex.org/W2130656719","https://openalex.org/W2137241556","https://openalex.org/W2146983845","https://openalex.org/W2147243248","https://openalex.org/W2148099625","https://openalex.org/W2152323124","https://openalex.org/W2155118487","https://openalex.org/W2157593452","https://openalex.org/W2159271152","https://openalex.org/W2404646356","https://openalex.org/W3135576591","https://openalex.org/W4251068371","https://openalex.org/W4387267678"],"related_works":["https://openalex.org/W3135576591","https://openalex.org/W2801459186","https://openalex.org/W3037368055","https://openalex.org/W7127533305","https://openalex.org/W4386913784","https://openalex.org/W7160028854","https://openalex.org/W4229372020","https://openalex.org/W7161592123","https://openalex.org/W2997837456","https://openalex.org/W6902328364"],"abstract_inverted_index":{"BACKGROUND:":[0],"Fine":[1],"particulate":[2],"matter":[3],"originating":[4],"from":[5,81],"traffic":[6,17,32],"correlates":[7],"with":[8,168,185,193,207,241],"increased":[9],"morbidity":[10],"and":[11,88,104,109,149,178,218,225],"mortality.":[12],"An":[13,58],"important":[14],"source":[15],"of":[16,22,29,36,45,137,145,152,171,196,202],"particles":[18,79,111,175,237,249],"is":[19],"brake":[20,54,99,235],"wear":[21,55,236,248],"cars":[23],"which":[24,180],"contributes":[25],"up":[26],"to":[27,40,51,78,259],"20%":[28],"the":[30,72,98,110,143,150,153,174,194,232],"total":[31],"emissions.":[33],"The":[34,91,121,157,200],"aim":[35],"this":[37,255],"study":[38],"was":[39,61,106,125,189,214],"evaluate":[41],"potential":[42],"toxicological":[43],"effects":[44],"human":[46],"epithelial":[47],"lung":[48],"cells":[49,69],"exposed":[50,77],"freshly":[52],"generated":[53],"particles.":[56],"RESULTS:":[57],"exposure":[59],"box":[60],"mounted":[62],"around":[63],"a":[64,242],"car's":[65],"braking":[66,84],"system.":[67],"Lung":[68],"cultured":[70],"at":[71],"air-liquid":[73],"interface":[74],"were":[75,119,133,181,204],"then":[76],"emitted":[80],"two":[82],"typical":[83],"behaviours":[85],"(\"full":[86],"stop\"":[87],"\"normal":[89],"deceleration\").":[90],"particle":[92],"size":[93],"distribution":[94],"as":[95,97],"well":[96],"emission":[100],"components":[101],"like":[102],"metals":[103,172,233],"carbons":[105],"measured":[107],"on-line,":[108],"deposited":[112],"on":[113,173,234],"grids":[114],"for":[115],"transmission":[116],"electron":[117],"microscopy":[118],"counted.":[120],"tight":[122,158,239],"junction":[123,159],"arrangement":[124],"observed":[126,215],"by":[127,135,141],"laser":[128],"scanning":[129],"microscopy.":[130],"Cellular":[131],"responses":[132],"assessed":[134],"measurement":[136],"lactate":[138],"dehydrogenase":[139],"(cytotoxicity),":[140],"investigating":[142],"production":[144],"reactive":[146,197,222],"oxidative":[147,198,223,245,264],"species":[148,224],"release":[151],"pro-inflammatory":[154,252],"mediator":[155],"interleukin-8.":[156,226],"protein":[160],"occludin":[161,217],"density":[162],"decreased":[163],"significantly":[164,205],"(p":[165],"<":[166],"0.05)":[167],"increasing":[169,208],"concentrations":[170,201],"(iron,":[176],"copper":[177],"manganese,":[179],"all":[182],"strongly":[183],"correlated":[184,192,206],"each":[186],"other).":[187],"Occludin":[188],"also":[190,250],"negatively":[191],"intensity":[195],"species.":[199],"interleukin-8":[203],"organic":[209],"carbon":[210],"concentrations.":[211],"No":[212],"correlation":[213],"between":[216,221],"interleukin-8,":[219],"nor":[220],"CONCLUSION:":[227],"These":[228],"findings":[229],"suggest":[230],"that":[231],"damage":[238],"junctions":[240],"mechanism":[243,261],"involving":[244],"stress.":[246,265],"Brake":[247],"increase":[251],"responses.":[253],"However,":[254],"might":[256],"be":[257],"due":[258],"another":[260],"than":[262],"via":[263]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":15},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":16},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}