{"id":"https://openalex.org/W2144589754","doi":"https://doi.org/10.3171/jns.1985.63.2.0155","title":"Intracranial germ-cell tumors: natural history and pathogenesis","display_name":"Intracranial germ-cell tumors: natural history and pathogenesis","publication_year":1985,"publication_date":"1985-08-01","ids":{"openalex":"https://openalex.org/W2144589754","doi":"https://doi.org/10.3171/jns.1985.63.2.0155","mag":"2144589754","pmid":"https://pubmed.ncbi.nlm.nih.gov/2991485"},"language":"en","primary_location":{"id":"doi:10.3171/jns.1985.63.2.0155","doi":"https://doi.org/10.3171/jns.1985.63.2.0155","is_oa":false,"landing_page_url":"https://doi.org/10.3171/jns.1985.63.2.0155","pdf_url":null,"source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2144589754"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061181330","display_name":"Mark T. Jennings","orcid":"https://orcid.org/0000-0001-6570-9481","observed_orcids":["https://orcid.org/0000-0001-6570-9481"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark T. Jennings","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Center, New York, New York; Harvard School of Public Health, Dana-Farber Cancer Institute, Harvard Medical School, and Massachusetts General Hospital, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, New York; Harvard School of Public Health, Dana-Farber Cancer Institute, Harvard Medical School, and Massachusetts General Hospital, Boston, Massachusetts","institution_ids":["https://openalex.org/I1334819555","https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210117453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062329369","display_name":"Rebecca Sue Gelman","orcid":"https://orcid.org/0000-0003-3189-4396","observed_orcids":["https://orcid.org/0000-0003-3189-4396"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebecca Gelman","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Center, New York, New York; Harvard School of Public Health, Dana-Farber Cancer Institute, Harvard Medical School, and Massachusetts General Hospital, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, New York; Harvard School of Public Health, Dana-Farber Cancer Institute, Harvard Medical School, and Massachusetts General Hospital, Boston, Massachusetts","institution_ids":["https://openalex.org/I1334819555","https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210117453"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055927065","display_name":"Fred H. Hochberg","orcid":"https://orcid.org/0000-0002-2765-8844","observed_orcids":["https://orcid.org/0000-0002-2765-8844"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fred Hochberg","raw_affiliation_strings":["Memorial Sloan-Kettering Cancer Center, New York, New York; Harvard School of Public Health, Dana-Farber Cancer Institute, Harvard Medical School, and Massachusetts General Hospital, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, New York; Harvard School of Public Health, Dana-Farber Cancer Institute, Harvard Medical School, and Massachusetts General Hospital, Boston, Massachusetts","institution_ids":["https://openalex.org/I1334819555","https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210117453"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.1405,"has_fulltext":false,"cited_by_count":829,"citation_normalized_percentile":{"value":0.87755102,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"63","issue":"2","first_page":"155","last_page":"167"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intracranial-germ-cell-tumors","display_name":"intracranial germ cell tumors","score":0.9909999966621399},{"id":"https://openalex.org/keywords/germinoma","display_name":"germinoma","score":0.9380000233650208},{"id":"https://openalex.org/keywords/non-germinomatous-germ-cell-tumors","display_name":"non-germinomatous germ cell tumors","score":0.890999972820282},{"id":"https://openalex.org/keywords/teratoma","display_name":"teratoma","score":0.9309999942779541},{"id":"https://openalex.org/keywords/embryonal-carcinoma","display_name":"embryonal carcinoma","score":0.9850000143051147},{"id":"https://openalex.org/keywords/yolk-sac-tumor","display_name":"yolk sac tumor","score":0.9779999852180481},{"id":"https://openalex.org/keywords/choriocarcinoma","display_name":"choriocarcinoma","score":0.9950000047683716},{"id":"https://openalex.org/keywords/suprasellar-cistern","display_name":"suprasellar cistern","score":0.781000018119812},{"id":"https://openalex.org/keywords/pineal-gland","display_name":"pineal gland","score":0.9200000166893005},{"id":"https://openalex.org/keywords/natural-history-disease","display_name":"natural history (disease)","score":0.6690000295639038},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.9419999718666077},{"id":"https://openalex.org/keywords/age-of-onset","display_name":"age of onset","score":0.6790000200271606},{"id":"https://openalex.org/keywords/diabetes-insipidus","display_name":"diabetes insipidus","score":0.7260000109672546},{"id":"https://openalex.org/keywords/third-ventricle","display_name":"third ventricle","score":0.671999990940094},{"id":"https://openalex.org/keywords/spinal-cord-metastases","display_name":"spinal cord metastasis","score":0.8640000224113464},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.796999990940094},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.6159999966621399},{"id":"https://openalex.org/keywords/histopathological-diagnosis","display_name":"histopathological diagnosis","score":0.7459999918937683},{"id":"https://openalex.org/keywords/disease-staging","display_name":"disease staging","score":0.6159999966621399}],"concepts":[{"id":"https://openalex.org/C2778895204","wikidata":"https://www.wikidata.org/wiki/Q950838","display_name":"Germinoma","level":3,"score":0.8928327560424805},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7650196552276611},{"id":"https://openalex.org/C2776938808","wikidata":"https://www.wikidata.org/wiki/Q1737977","display_name":"Germ cell tumors","level":3,"score":0.7599132061004639},{"id":"https://openalex.org/C2781171461","wikidata":"https://www.wikidata.org/wiki/Q662322","display_name":"Third ventricle","level":2,"score":0.5829976797103882},{"id":"https://openalex.org/C2778134817","wikidata":"https://www.wikidata.org/wiki/Q193003","display_name":"Hydrocephalus","level":2,"score":0.5362761616706848},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5009160041809082},{"id":"https://openalex.org/C2780059843","wikidata":"https://www.wikidata.org/wiki/Q198654","display_name":"Pineal gland","level":3,"score":0.47653302550315857},{"id":"https://openalex.org/C92487007","wikidata":"https://www.wikidata.org/wiki/Q838858","display_name":"Cistern","level":2,"score":0.44154343008995056},{"id":"https://openalex.org/C2776252090","wikidata":"https://www.wikidata.org/wiki/Q1269251","display_name":"Dysgerminoma","level":3,"score":0.4348500967025757},{"id":"https://openalex.org/C2776958162","wikidata":"https://www.wikidata.org/wiki/Q220551","display_name":"Diabetes insipidus","level":2,"score":0.4236501455307007},{"id":"https://openalex.org/C2779342463","wikidata":"https://www.wikidata.org/wiki/Q3542021","display_name":"Endodermal sinus tumor","level":4,"score":0.42188766598701477},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.27419760823249817},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2519763112068176},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.23905310034751892},{"id":"https://openalex.org/C2778324911","wikidata":"https://www.wikidata.org/wiki/Q9631","display_name":"Ovary","level":2,"score":0.1653769612312317},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.1653173863887787},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.09902337193489075},{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.0},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.0},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002551","descriptor_name":"Cerebral Ventricle Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004407","descriptor_name":"Dysgerminoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009373","descriptor_name":"Neoplasms, Germ Cell and Embryonal","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D009373","descriptor_name":"Neoplasms, Germ Cell and Embryonal","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D009373","descriptor_name":"Neoplasms, Germ Cell and Embryonal","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009373","descriptor_name":"Neoplasms, Germ Cell and Embryonal","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010870","descriptor_name":"Pineal Gland","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012658","descriptor_name":"Sella Turcica","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3171/jns.1985.63.2.0155","doi":"https://doi.org/10.3171/jns.1985.63.2.0155","is_oa":false,"landing_page_url":"https://doi.org/10.3171/jns.1985.63.2.0155","pdf_url":null,"source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},{"id":"pmid:2991485","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2991485","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurosurgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":149,"referenced_works":["https://openalex.org/W7769330","https://openalex.org/W85852504","https://openalex.org/W224993226","https://openalex.org/W642402266","https://openalex.org/W658705493","https://openalex.org/W1516870034","https://openalex.org/W1520815794","https://openalex.org/W1521712583","https://openalex.org/W1525261957","https://openalex.org/W1526196099","https://openalex.org/W1533252986","https://openalex.org/W1533936180","https://openalex.org/W1539889348","https://openalex.org/W1563399474","https://openalex.org/W1568488195","https://openalex.org/W1574083688","https://openalex.org/W1580788756","https://openalex.org/W1581672612","https://openalex.org/W1586172383","https://openalex.org/W1643419149","https://openalex.org/W1806971213","https://openalex.org/W1966073767","https://openalex.org/W1966452163","https://openalex.org/W1967131869","https://openalex.org/W1968583117","https://openalex.org/W1969044867","https://openalex.org/W1969642123","https://openalex.org/W1970710115","https://openalex.org/W1971256432","https://openalex.org/W1971567259","https://openalex.org/W1972783392","https://openalex.org/W1973599693","https://openalex.org/W1974427001","https://openalex.org/W1978945477","https://openalex.org/W1979300931","https://openalex.org/W1982892737","https://openalex.org/W1984333600","https://openalex.org/W1985124392","https://openalex.org/W1985523800","https://openalex.org/W1985886369","https://openalex.org/W1985974775","https://openalex.org/W1986626382","https://openalex.org/W1986723543","https://openalex.org/W1986931252","https://openalex.org/W1989808599","https://openalex.org/W1989965370","https://openalex.org/W1990071979","https://openalex.org/W1990151276","https://openalex.org/W1991317562","https://openalex.org/W1996532525","https://openalex.org/W1998253655","https://openalex.org/W2000908282","https://openalex.org/W2002022638","https://openalex.org/W2003504882","https://openalex.org/W2005008837","https://openalex.org/W2006371018","https://openalex.org/W2006510233","https://openalex.org/W2010322497","https://openalex.org/W2010635282","https://openalex.org/W2012373409","https://openalex.org/W2017451421","https://openalex.org/W2020623052","https://openalex.org/W2021063622","https://openalex.org/W2021711131","https://openalex.org/W2029501792","https://openalex.org/W2030828955","https://openalex.org/W2032641816","https://openalex.org/W2034649399","https://openalex.org/W2036012463","https://openalex.org/W2039503978","https://openalex.org/W2041329942","https://openalex.org/W2042918601","https://openalex.org/W2043112793","https://openalex.org/W2044498519","https://openalex.org/W2047978829","https://openalex.org/W2049820186","https://openalex.org/W2050170174","https://openalex.org/W2053617168","https://openalex.org/W2054245748","https://openalex.org/W2055181395","https://openalex.org/W2055824980","https://openalex.org/W2057718016","https://openalex.org/W2058209675","https://openalex.org/W2058762033","https://openalex.org/W2059281221","https://openalex.org/W2059752054","https://openalex.org/W2061340696","https://openalex.org/W2061684524","https://openalex.org/W2068716774","https://openalex.org/W2073162521","https://openalex.org/W2073366959","https://openalex.org/W2074440299","https://openalex.org/W2077503905","https://openalex.org/W2082962590","https://openalex.org/W2086641200","https://openalex.org/W2086869735","https://openalex.org/W2088543470","https://openalex.org/W2093068662","https://openalex.org/W2093190293","https://openalex.org/W2093455466","https://openalex.org/W2095197897","https://openalex.org/W2095516242","https://openalex.org/W2097229296","https://openalex.org/W2102230530","https://openalex.org/W2107434592","https://openalex.org/W2108073862","https://openalex.org/W2110470458","https://openalex.org/W2111040799","https://openalex.org/W2119254217","https://openalex.org/W2122074354","https://openalex.org/W2128475251","https://openalex.org/W2129940427","https://openalex.org/W2133558963","https://openalex.org/W2150512917","https://openalex.org/W2154750829","https://openalex.org/W2156348726","https://openalex.org/W2303549362","https://openalex.org/W2312728425","https://openalex.org/W2315332919","https://openalex.org/W2321706122","https://openalex.org/W2334989489","https://openalex.org/W2336273811","https://openalex.org/W2408967079","https://openalex.org/W2409108975","https://openalex.org/W2411070862","https://openalex.org/W2411521165","https://openalex.org/W2411717451","https://openalex.org/W2412426592","https://openalex.org/W2415923462","https://openalex.org/W2416972644","https://openalex.org/W2416996668","https://openalex.org/W2417498425","https://openalex.org/W2422170001","https://openalex.org/W2430669901","https://openalex.org/W2431707050","https://openalex.org/W2439537654","https://openalex.org/W2460530301","https://openalex.org/W2461432610","https://openalex.org/W2474152111","https://openalex.org/W2797936250","https://openalex.org/W2900550621","https://openalex.org/W2992676442","https://openalex.org/W2996771582","https://openalex.org/W3041047318","https://openalex.org/W3147894994","https://openalex.org/W4232729276","https://openalex.org/W4235965067","https://openalex.org/W4322702032","https://openalex.org/W6999871186"],"related_works":["https://openalex.org/W2557137276","https://openalex.org/W1966073767","https://openalex.org/W161026393","https://openalex.org/W2076234920","https://openalex.org/W2203909836","https://openalex.org/W2026255391","https://openalex.org/W4285734090","https://openalex.org/W2172128741","https://openalex.org/W1970416955","https://openalex.org/W2971915352"],"abstract_inverted_index":{"The":[0,64,88,291,320],"natural":[1],"history":[2],"of":[3,16,39,66,91,109,118,126,208,216,239,242,249,251,273,278,281,287,293,301,336,346],"primary":[4],"intracranial":[5],"germ-cell":[6],"tumors":[7,187],"(GCT's)":[8],"is":[9,94],"defined":[10],"from":[11,47],"389":[12],"previously":[13],"published":[14],"cases,":[15],"which":[17],"65%":[18],"were":[19,215,223],"germinomas,":[20],"18%":[21],"teratomas,":[22],"5%":[23,31],"embryonal":[24,348],"carcinomas,":[25],"7%":[26],"endodermal":[27],"sinus":[28],"tumors,":[29],"and":[30,57,115,154,170,183,201,236,276,309],"choriocarcinomas.":[32],"Intracranial":[33],"GCT's":[34,77,121,150,174,231,294],"display":[35],"specificity":[36,300],"in":[37,70,101,103,143,148,285,323,342],"site":[38],"origin.":[40],"Ninety-five":[41],"percent":[42],"arise":[43,69],"along":[44],"the":[45,48,53,71,81,104,190,197,240,246,252,271,279,304,318,333,343],"midline":[46],"suprasellar":[49,72,149],"cistern":[50],"(37%)":[51],"to":[52,139,195,328],"pineal":[54,82],"gland":[55,83],"(48%),":[56],"an":[58,98,123,339],"additional":[59],"6%":[60],"involve":[61,80,196],"both":[62],"sites.":[63],"majority":[65],"germinomas":[67,130,144,161,222],"(57%)":[68],"cistern,":[73],"while":[74],"most":[75],"nongerminomatous":[76,230],"(68%)":[78],"preferentially":[79],"(p":[84,131,145,151,157,232,254,259,265],"less":[85,132,233],"than":[86,128,133,229,234],"0.0001).":[87,134],"age":[89,125,324],"distribution":[90,325],"afflicted":[92],"patients":[93,110],"unimodal,":[95],"centering":[96],"with":[97,164,181,225],"abrupt":[99,321],"surge":[100],"frequency":[102],"early":[105],"pubertal":[106],"years;":[107],"68%":[108],"are":[111,141,283,338],"diagnosed":[112],"between":[113],"10":[114,327],"21":[116],"years":[117,330],"age.":[119],"Nongerminomatous":[120,173],"demonstrate":[122],"earlier":[124],"onset":[127],"do":[129],"Prolonged":[135],"symptomatic":[136],"intervals":[137],"prior":[138],"diagnosis":[140,275],"common":[142],"=":[146,152,158,255,260,266],"0.0007),":[147],"0.001),":[153],"among":[155],"females":[156],"0.02).":[159],"Parasellar":[160],"commonly":[162],"present":[163,175],"diabetes":[165],"insipidus,":[166],"visual":[167],"field":[168],"defects,":[169],"hypothalamic-pituitary":[171],"failure.":[172],"as":[176],"posterior":[177],"third":[178,198,257],"ventricular":[179],"masses":[180],"hydrocephalus":[182],"midbrain":[184],"compression.":[185],"Germ-cell":[186],"may":[188,295],"infiltrate":[189],"hypothalamus":[191,253],"(11%),":[192],"or":[193,262],"disseminate":[194],"ventricle":[199,258],"(22%)":[200],"spinal":[202,263],"cord":[203,264],"(10%).":[204],"Among":[205],"a":[206],"subpopulation":[207],"263":[209],"conventionally":[210],"treated":[211],"patients,":[212],"two":[213],"factors":[214],"prognostic":[217],"significance:":[218],"1)":[219],"histological":[220,274],"diagnosis;":[221],"associated":[224],"significantly":[226],"longer":[227],"survival":[228],"0.0001);":[235],"2)":[237],"staging":[238,277],"extent":[241,280],"disease;":[243],"this":[244],"emphasizes":[245],"ominous":[247],"character":[248],"involvement":[250],"0.0002),":[256],"0.02),":[261],"0.01).":[267],"Specific":[268],"recommendations":[269],"regarding":[270],"necessity":[272],"disease":[282],"made":[284],"light":[286],"modern":[288],"chemotherapeutic":[289],"advances.":[290],"pathogenesis":[292],"be":[296],"revealed":[297],"by":[298],"their":[299],"origin":[302],"within":[303,317],"positive":[305],"(suprasellar":[306],"cistern-suprachiasmatic":[307],"nucleus)":[308],"negative":[310],"(pineal)":[311],"regulatory":[312],"centers":[313],"for":[314],"gonadotropin":[315],"secretion":[316],"diencephalon.":[319],"rise":[322],"at":[326],"12":[329],"suggests":[331],"that":[332],"neuroendocrine":[334],"events":[335],"puberty":[337],"\"activating\"":[340],"influence":[341],"malignant":[344],"expression":[345],"these":[347],"tumors.":[349]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":22},{"year":2023,"cited_by_count":28},{"year":2022,"cited_by_count":30},{"year":2021,"cited_by_count":21},{"year":2020,"cited_by_count":36},{"year":2019,"cited_by_count":23},{"year":2018,"cited_by_count":22},{"year":2017,"cited_by_count":28},{"year":2016,"cited_by_count":31},{"year":2015,"cited_by_count":24},{"year":2014,"cited_by_count":28},{"year":2013,"cited_by_count":25},{"year":2012,"cited_by_count":32}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}
