{"id":"https://openalex.org/W2143201729","doi":"https://doi.org/10.1016/s0021-9150(97)00132-9","title":"Localization and activity of tissue factor in human aortic atherosclerotic lesions","display_name":"Localization and activity of tissue factor in human aortic atherosclerotic lesions","publication_year":1997,"publication_date":"1997-09-01","ids":{"openalex":"https://openalex.org/W2143201729","doi":"https://doi.org/10.1016/s0021-9150(97)00132-9","mag":"2143201729","pmid":"https://pubmed.ncbi.nlm.nih.gov/9298681"},"language":"en","primary_location":{"id":"doi:10.1016/s0021-9150(97)00132-9","doi":"https://doi.org/10.1016/s0021-9150(97)00132-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0021-9150(97)00132-9","pdf_url":null,"source":{"id":"https://openalex.org/S206830620","display_name":"Atherosclerosis","issn_l":"0021-9150","issn":["0021-9150","1879-1484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Atherosclerosis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044933503","display_name":"Kinta Hatakeyama","orcid":"https://orcid.org/0000-0001-7729-1836","observed_orcids":["https://orcid.org/0000-0001-7729-1836"]},"institutions":[{"id":"https://openalex.org/I118574687","display_name":"University of Miyazaki","ror":"https://ror.org/0447kww10","country_code":"JP","type":"education","lineage":["https://openalex.org/I118574687"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kinta Hatakeyama","raw_affiliation_strings":["First Department of Pathology, Miyazaki Medical College, Kiyotake, Japan","First Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Pathology, Miyazaki Medical College, Kiyotake, Japan","institution_ids":[]},{"raw_affiliation_string":"First Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan","institution_ids":["https://openalex.org/I118574687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051382077","display_name":"Yujiro Asada","orcid":"https://orcid.org/0000-0001-5105-2159","observed_orcids":["https://orcid.org/0000-0001-5105-2159"]},"institutions":[{"id":"https://openalex.org/I118574687","display_name":"University of Miyazaki","ror":"https://ror.org/0447kww10","country_code":"JP","type":"education","lineage":["https://openalex.org/I118574687"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yujiro Asada","raw_affiliation_strings":["First Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan","institution_ids":["https://openalex.org/I118574687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113652362","display_name":"Kousuke Marutsuka","orcid":"https://orcid.org/0009-0005-2302-4069","observed_orcids":["https://orcid.org/0009-0005-2302-4069"]},"institutions":[{"id":"https://openalex.org/I118574687","display_name":"University of Miyazaki","ror":"https://ror.org/0447kww10","country_code":"JP","type":"education","lineage":["https://openalex.org/I118574687"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kousuke Marutsuka","raw_affiliation_strings":["First Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan","institution_ids":["https://openalex.org/I118574687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011382201","display_name":"Yuichiro Z. Sato","orcid":"https://orcid.org/0000-0003-1171-2620","observed_orcids":["https://orcid.org/0000-0003-1171-2620"]},"institutions":[{"id":"https://openalex.org/I118574687","display_name":"University of Miyazaki","ror":"https://ror.org/0447kww10","country_code":"JP","type":"education","lineage":["https://openalex.org/I118574687"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuichiro Sato","raw_affiliation_strings":["First Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan","institution_ids":["https://openalex.org/I118574687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069381583","display_name":"Yuichi Kamikubo","orcid":"https://orcid.org/0009-0002-6614-7411","observed_orcids":["https://orcid.org/0009-0002-6614-7411"]},"institutions":[{"id":"https://openalex.org/I4210129349","display_name":"Kaketsuken (Japan)","ror":"https://ror.org/037x16a12","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210129349"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuichi Kamikubo","raw_affiliation_strings":["The Chemo-Sero-Therapeutic Research Institute, Kumamoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Chemo-Sero-Therapeutic Research Institute, Kumamoto, Japan","institution_ids":["https://openalex.org/I4210129349"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111436623","display_name":"Akinobu Sumiyoshi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118574687","display_name":"University of Miyazaki","ror":"https://ror.org/0447kww10","country_code":"JP","type":"education","lineage":["https://openalex.org/I118574687"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Akinobu Sumiyoshi","raw_affiliation_strings":["First Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-16, Japan","institution_ids":["https://openalex.org/I118574687"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5111436623"],"corresponding_institution_ids":["https://openalex.org/I118574687"],"apc_list":{"value":4020,"currency":"USD","value_usd":4020},"apc_paid":null,"fwci":3.5124,"has_fulltext":false,"cited_by_count":134,"citation_normalized_percentile":{"value":0.92871176,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"133","issue":"2","first_page":"213","last_page":"219"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11917","display_name":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tissue-factor","display_name":"tissue factor","score":1.0},{"id":"https://openalex.org/keywords/aortic-atherosclerotic-lesions","display_name":"aortic atherosclerotic lesions","score":0.765999972820282},{"id":"https://openalex.org/keywords/thrombosis","display_name":"thrombosis","score":0.7179999947547913},{"id":"https://openalex.org/keywords/factor-x-activation","display_name":"factor X activation","score":0.968999981880188},{"id":"https://openalex.org/keywords/intimal-thickening","display_name":"intimal thickening","score":0.6949999928474426},{"id":"https://openalex.org/keywords/fatty-streaks","display_name":"fatty streaks","score":0.8629999756813049},{"id":"https://openalex.org/keywords/atherosclerotic-plaque","display_name":"atherosclerotic plaque","score":0.9660000205039978},{"id":"https://openalex.org/keywords/smooth-muscle-cells","display_name":"smooth muscle cells","score":0.7609999775886536},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.9890000224113464},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.925000011920929},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.8529999852180481},{"id":"https://openalex.org/keywords/blood-coagulation","display_name":"coagulation","score":0.7889999747276306}],"concepts":[{"id":"https://openalex.org/C186738567","wikidata":"https://www.wikidata.org/wiki/Q412841","display_name":"Tissue factor","level":3,"score":0.8959351181983948},{"id":"https://openalex.org/C2778116356","wikidata":"https://www.wikidata.org/wiki/Q5438018","display_name":"Fatty streak","level":3,"score":0.823246419429779},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.6671586632728577},{"id":"https://openalex.org/C144594695","wikidata":"https://www.wikidata.org/wiki/Q6153218","display_name":"Thromboplastin","level":3,"score":0.48902711272239685},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.47197896242141724},{"id":"https://openalex.org/C204628709","wikidata":"https://www.wikidata.org/wiki/Q864854","display_name":"Biotinylation","level":2,"score":0.45386314392089844},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4026373028755188},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33122241497039795},{"id":"https://openalex.org/C2778382381","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Coagulation","level":2,"score":0.29848340153694153},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1083877682685852},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08687829971313477}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001013","descriptor_name":"Aorta, Thoracic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001013","descriptor_name":"Aorta, Thoracic","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001710","descriptor_name":"Biotin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002863","descriptor_name":"Chromogenic Compounds","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005170","descriptor_name":"Factor X","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005170","descriptor_name":"Factor X","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013925","descriptor_name":"Thromboplastin","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013925","descriptor_name":"Thromboplastin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013925","descriptor_name":"Thromboplastin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015942","descriptor_name":"Factor VIIa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015942","descriptor_name":"Factor VIIa","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0021-9150(97)00132-9","doi":"https://doi.org/10.1016/s0021-9150(97)00132-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0021-9150(97)00132-9","pdf_url":null,"source":{"id":"https://openalex.org/S206830620","display_name":"Atherosclerosis","issn_l":"0021-9150","issn":["0021-9150","1879-1484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Atherosclerosis","raw_type":"journal-article"},{"id":"pmid:9298681","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9298681","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Atherosclerosis","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3699797160","display_name":null,"funder_award_id":"06670236","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W56015030","https://openalex.org/W178032782","https://openalex.org/W268231381","https://openalex.org/W1507312029","https://openalex.org/W1512144932","https://openalex.org/W1528445591","https://openalex.org/W1567544003","https://openalex.org/W1963879827","https://openalex.org/W1986070811","https://openalex.org/W1992803891","https://openalex.org/W1995387334","https://openalex.org/W2019673194","https://openalex.org/W2034656907","https://openalex.org/W2039010543","https://openalex.org/W2054940625","https://openalex.org/W2061886045","https://openalex.org/W2075829745","https://openalex.org/W2083679231","https://openalex.org/W2090203672","https://openalex.org/W2092956019","https://openalex.org/W2110404024","https://openalex.org/W2118292856","https://openalex.org/W2137570167","https://openalex.org/W2150608680","https://openalex.org/W2158974240","https://openalex.org/W2220166796","https://openalex.org/W2414788117","https://openalex.org/W3112270648","https://openalex.org/W3194355700","https://openalex.org/W4212838803","https://openalex.org/W4239861433"],"related_works":["https://openalex.org/W1986070811","https://openalex.org/W2606537142","https://openalex.org/W2082332814","https://openalex.org/W2145483534","https://openalex.org/W1897671456","https://openalex.org/W2383513421","https://openalex.org/W2040661685","https://openalex.org/W2083679231","https://openalex.org/W204623194","https://openalex.org/W2085059196"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}