{"id":"https://openalex.org/W2141413046","doi":"https://doi.org/10.1093/jnci/dji281","title":"Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation-Negative Hereditary Breast Cancer Families","display_name":"Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation-Negative Hereditary Breast Cancer Families","publication_year":2005,"publication_date":"2005-09-20","ids":{"openalex":"https://openalex.org/W2141413046","doi":"https://doi.org/10.1093/jnci/dji281","mag":"2141413046","pmid":"https://pubmed.ncbi.nlm.nih.gov/16174860"},"language":"en","primary_location":{"id":"doi:10.1093/jnci/dji281","doi":"https://doi.org/10.1093/jnci/dji281","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnci/dji281","pdf_url":"https://academic.oup.com/jnci/article-pdf/97/18/1382/7686635/dji281.pdf","source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/jnci/article-pdf/97/18/1382/7686635/dji281.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000753119","display_name":"Noah D. Kauff","orcid":"https://orcid.org/0000-0001-7242-6156","observed_orcids":["https://orcid.org/0000-0001-7242-6156"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Noah D. Kauff","raw_affiliation_strings":["Department of Gynecology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038915889","display_name":"Nandita Mitra","orcid":"https://orcid.org/0000-0002-7714-3910","observed_orcids":["https://orcid.org/0000-0002-7714-3910"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nandita Mitra","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045514288","display_name":"Mark E. Robson","orcid":"https://orcid.org/0000-0002-3109-1692","observed_orcids":["https://orcid.org/0000-0002-3109-1692"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark E. Robson","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108789317","display_name":"Karen E. Hurley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen E. Hurley","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046139930","display_name":"Shaokun Chuai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shaokun Chuai","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082399492","display_name":"Deborah J. Goldfrank","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deborah Goldfrank","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109074540","display_name":"E. Wadsworth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eve Wadsworth","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016399792","display_name":"Johanna Lee","orcid":"https://orcid.org/0000-0002-4290-9031","observed_orcids":["https://orcid.org/0000-0002-4290-9031"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Johanna Lee","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004522625","display_name":"Tessa Cigler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tessa Cigler","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038968411","display_name":"Patrick Ivan Borgen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick I. Borgen","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039225060","display_name":"Larry Norton","orcid":"https://orcid.org/0000-0003-3701-9250","observed_orcids":["https://orcid.org/0000-0003-3701-9250"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Larry Norton","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102075635","display_name":"Richard R. Barakat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard R. Barakat","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001757617","display_name":"Kenneth Offit","orcid":"https://orcid.org/0000-0002-2180-2032","observed_orcids":["https://orcid.org/0000-0002-2180-2032"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth Offit","raw_affiliation_strings":["Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","Department of Epidemiology and Biostatistics (NM, SC)","Department of Psychiatry and Behavioral Sciences (KEH)","Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine; Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery; Department of Epidemiology and Biostatistics (NM, SC); Department of Psychiatry and Behavioral Sciences (KEH); Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Affiliations of authors: Clinical Genetics (NDK, MER, KEH, DG, EW, JL, TC, KO) and Breast Cancer Medicine Services (MER, LN), Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics (NM, SC)","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Behavioral Sciences (KEH)","institution_ids":[]},{"raw_affiliation_string":"Gynecology (NDK, RRB) and Breast Services (PIB), Department of Surgery","institution_ids":[]},{"raw_affiliation_string":"Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5000753119"],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":{"value":5436,"currency":"USD","value_usd":5436},"apc_paid":{"value":5436,"currency":"USD","value_usd":5436},"fwci":3.3279,"has_fulltext":true,"cited_by_count":70,"citation_normalized_percentile":{"value":0.92949297,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"97","issue":"18","first_page":"1382","last_page":"1384"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14078","display_name":"Multiple and Secondary Primary Cancers","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ovarian-cancer-risk","display_name":"ovarian cancer risk","score":0.9319999814033508},{"id":"https://openalex.org/keywords/hereditary-breast-cancer","display_name":"hereditary breast cancer","score":0.8889999985694885},{"id":"https://openalex.org/keywords/brca1-mutation","display_name":"BRCA1 mutation","score":0.8429999947547913},{"id":"https://openalex.org/keywords/brca2-mutation","display_name":"BRCA2 mutation","score":1.0},{"id":"https://openalex.org/keywords/familial-cancer-risk","display_name":"familial cancer risk","score":0.5609999895095825},{"id":"https://openalex.org/keywords/standardized-incidence-ratio","display_name":"standardized incidence ratio","score":0.8050000071525574},{"id":"https://openalex.org/keywords/breast-cancer-incidence","display_name":"breast cancer incidence","score":0.5870000123977661},{"id":"https://openalex.org/keywords/genetic-testing","display_name":"genetic testing","score":0.6729999780654907}],"concepts":[{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.7965804934501648},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7747397422790527},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7201864719390869},{"id":"https://openalex.org/C2780194787","wikidata":"https://www.wikidata.org/wiki/Q4836333","display_name":"BRCA mutation","level":4,"score":0.7159157395362854},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6379727125167847},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.563409149646759},{"id":"https://openalex.org/C188997412","wikidata":"https://www.wikidata.org/wiki/Q1640386","display_name":"Proband","level":4,"score":0.5321857929229736},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5190446972846985},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5168062448501587},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.4749474823474884},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4708128869533539},{"id":"https://openalex.org/C80227256","wikidata":"https://www.wikidata.org/wiki/Q1124169","display_name":"Genetic counseling","level":2,"score":0.4552319645881653},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.44615206122398376},{"id":"https://openalex.org/C2780673598","wikidata":"https://www.wikidata.org/wiki/Q285223","display_name":"Genetic testing","level":2,"score":0.44219422340393066},{"id":"https://openalex.org/C63592243","wikidata":"https://www.wikidata.org/wiki/Q5382717","display_name":"Epidemiology of cancer","level":4,"score":0.4309130907058716},{"id":"https://openalex.org/C2909462720","wikidata":"https://www.wikidata.org/wiki/Q421651","display_name":"BRCA2 Protein","level":5,"score":0.42433255910873413},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.35221680998802185},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.32905542850494385},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1647806465625763},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12409773468971252},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005820","descriptor_name":"Genetic Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007585","descriptor_name":"Jews","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007585","descriptor_name":"Jews","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016001","descriptor_name":"Confidence Intervals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018426","descriptor_name":"SEER Program","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019398","descriptor_name":"Genes, BRCA1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024522","descriptor_name":"Genes, BRCA2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/jnci/dji281","doi":"https://doi.org/10.1093/jnci/dji281","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnci/dji281","pdf_url":"https://academic.oup.com/jnci/article-pdf/97/18/1382/7686635/dji281.pdf","source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},{"id":"pmid:16174860","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16174860","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the National Cancer Institute","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.556.509","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.556.509","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jnci.oxfordjournals.org/content/97/18/1382.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1093/jnci/dji281","doi":"https://doi.org/10.1093/jnci/dji281","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnci/dji281","pdf_url":"https://academic.oup.com/jnci/article-pdf/97/18/1382/7686635/dji281.pdf","source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320314458","display_name":"National Comprehensive Cancer Network","ror":"https://ror.org/0465x5x63"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2141413046.pdf","grobid_xml":"https://content.openalex.org/works/W2141413046.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1589782664","https://openalex.org/W1999130958","https://openalex.org/W2002655996","https://openalex.org/W2022389650","https://openalex.org/W2061071119","https://openalex.org/W2091961739","https://openalex.org/W2098054190","https://openalex.org/W2102292863","https://openalex.org/W2103970959","https://openalex.org/W2112008163","https://openalex.org/W2126703127","https://openalex.org/W2143730928","https://openalex.org/W2145828336","https://openalex.org/W2147406390","https://openalex.org/W2150111967","https://openalex.org/W2724744060","https://openalex.org/W3085323863","https://openalex.org/W4236095073"],"related_works":["https://openalex.org/W2285896165","https://openalex.org/W2108744675","https://openalex.org/W1571891420","https://openalex.org/W2333088314","https://openalex.org/W2021512912","https://openalex.org/W2074553519","https://openalex.org/W2017766075","https://openalex.org/W2057325637","https://openalex.org/W1989313702","https://openalex.org/W2315815669"],"abstract_inverted_index":{"Women":[0],"from":[1,28,51,67,123,128,213],"site-specific":[2,70,216],"hereditary":[3,29,54],"breast":[4,30,55,71,91,160,217],"cancer":[5,31,45,56,72,125,161,188,218],"families":[6,32,57,99,219],"who":[7,33,74],"carry":[8,36],"a":[9,38],"BRCA1":[10],"or":[11],"BRCA2":[12],"mutation":[13,39],"are":[14,40,58,220],"at":[15,42,59,79,222],"increased":[16,43,60,223],"risk":[17,61,224],"for":[18,62,225],"ovarian":[19,44,63,93,187,226],"cancer.":[20,227],"It":[21],"is":[22],"less":[23],"clear,":[24],"however,":[25],"whether":[26,49],"individuals":[27],"do":[34],"not":[35,221],"such":[37],"also":[41],"risk.":[46],"To":[47],"determine":[48],"women":[50,212],"BRCA":[52,68,214],"mutation-negative":[53],"cancer,":[64],"199":[65],"probands":[66,96],"mutation-negative,":[69,215],"kindreds":[73],"consented":[75],"to":[76,178,203],"prospective":[77],"follow-up":[78,152],"the":[80,129,139],"time":[81],"of":[82,89,102,114,141,151,159,186],"genetic":[83,104],"testing":[84],"were":[85,121,146,162,167],"identified.":[86],"The":[87,111],"incidence":[88,118,126],"new":[90,157],"and":[92,97,116,132,183],"cancers":[94,115],"in":[95,153],"their":[98,103],"since":[100],"receipt":[101],"test":[105],"results":[106,209],"was":[107,189,194],"determined":[108,122],"by":[109,137],"questionnaire.":[110],"expected":[112,168,195],"number":[113],"standardized":[117],"ratios":[119],"(SIRs)":[120],"age-specific":[124],"rates":[127],"Surveillance,":[130],"Epidemiology,":[131],"End":[133],"Results":[134],"(SEER)":[135],"program":[136],"using":[138],"method":[140],"Byar.":[142],"All":[143],"statistical":[144],"tests":[145],"two-sided.":[147],"During":[148],"2534":[149],"women-years":[150],"165":[154],"kindreds,":[155],"19":[156],"cases":[158],"diagnosed,":[163,190],"whereas":[164,191],"only":[165,192],"6.07":[166],"(SIR":[169,196],"=":[170,176,197,201,206],"3.13,":[171],"95%":[172,199],"confidence":[173],"interval":[174],"[CI]":[175],"1.88":[177],"4.89;":[179],"P":[180,205],"<":[181],".001),":[182],"one":[184],"case":[185],"0.66":[193],"1.52,":[198],"CI":[200],"0.02":[202],"8.46;":[204],".48).":[207],"These":[208],"suggest":[210],"that":[211]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
