{"id":"https://openalex.org/W2140459402","doi":"https://doi.org/10.1089/ten.teb.2008.0153","title":"Microcomputed Tomography Characterization of Neovascularization in Bone Tissue Engineering Applications","display_name":"Microcomputed Tomography Characterization of Neovascularization in Bone Tissue Engineering Applications","publication_year":2008,"publication_date":"2008-07-25","ids":{"openalex":"https://openalex.org/W2140459402","doi":"https://doi.org/10.1089/ten.teb.2008.0153","mag":"2140459402","pmid":"https://pubmed.ncbi.nlm.nih.gov/18657028","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2761680"},"language":"en","primary_location":{"id":"doi:10.1089/ten.teb.2008.0153","doi":"https://doi.org/10.1089/ten.teb.2008.0153","is_oa":false,"landing_page_url":"https://doi.org/10.1089/ten.teb.2008.0153","pdf_url":null,"source":{"id":"https://openalex.org/S13647896","display_name":"Tissue Engineering Part B Reviews","issn_l":"1937-3368","issn":["1937-3368","1937-3376"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering Part B: Reviews","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2761680","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082834975","display_name":"Simon W. Young","orcid":"https://orcid.org/0000-0002-8198-7083","observed_orcids":["https://orcid.org/0000-0002-8198-7083"]},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Simon Young","raw_affiliation_strings":["Department of Bioengineering, Rice University, Houston, Texas","Department of Bioengineering, Rice University , Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, Rice University, Houston, Texas","institution_ids":["https://openalex.org/I74775410"]},{"raw_affiliation_string":"Department of Bioengineering, Rice University , Houston, Texas, USA","institution_ids":["https://openalex.org/I74775410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014651312","display_name":"James D. Kretlow","orcid":"https://orcid.org/0000-0003-1437-1673","observed_orcids":["https://orcid.org/0000-0003-1437-1673"]},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James D. Kretlow","raw_affiliation_strings":["Department of Bioengineering, Rice University, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, Rice University, Houston, Texas","institution_ids":["https://openalex.org/I74775410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078269078","display_name":"Charles Nguyen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles Nguyen","raw_affiliation_strings":["Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center at Houston, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center at Houston, Houston, Texas","institution_ids":["https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016559951","display_name":"Alex G. Bashoura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alex G. Bashoura","raw_affiliation_strings":["Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center at Houston, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center at Houston, Houston, Texas","institution_ids":["https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087908733","display_name":"L. Scott Baggett","orcid":"https://orcid.org/0000-0002-6272-5096","observed_orcids":["https://orcid.org/0000-0002-6272-5096"]},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Scott Baggett","raw_affiliation_strings":["Department of Statistics, Rice University, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, Rice University, Houston, Texas","institution_ids":["https://openalex.org/I74775410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090135028","display_name":"John A. Jansen","orcid":"https://orcid.org/0000-0003-3077-8617","observed_orcids":["https://orcid.org/0000-0003-3077-8617"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"John A. Jansen","raw_affiliation_strings":["Department of Periodontology and Biomaterials, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontology and Biomaterials, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103209127","display_name":"Mark E. Wong","orcid":"https://orcid.org/0000-0002-7556-7592","observed_orcids":["https://orcid.org/0000-0002-7556-7592"]},"institutions":[{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Wong","raw_affiliation_strings":["Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center at Houston, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center at Houston, Houston, Texas","institution_ids":["https://openalex.org/I919571938"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059620644","display_name":"Antonios G. Mikos","orcid":"https://orcid.org/0000-0002-0709-990X","observed_orcids":["https://orcid.org/0000-0002-0709-990X"]},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Antonios G. Mikos","raw_affiliation_strings":["Department of Bioengineering, Rice University, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, Rice University, Houston, Texas","institution_ids":["https://openalex.org/I74775410"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3506,"has_fulltext":false,"cited_by_count":63,"citation_normalized_percentile":{"value":0.38030888,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"14","issue":"3","first_page":"295","last_page":"306"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neovascularization","display_name":"neovascularization","score":0.9319999814033508},{"id":"https://openalex.org/keywords/bone-tissue-engineering","display_name":"bone tissue engineering","score":0.9649999737739563},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.800000011920929},{"id":"https://openalex.org/keywords/vasculogenesis","display_name":"vasculogenesis","score":0.9639999866485596},{"id":"https://openalex.org/keywords/micro-computed-tomography","display_name":"micro-computed tomography","score":0.9549999833106995},{"id":"https://openalex.org/keywords/contrast-enhanced-micro-ct","display_name":"contrast-enhanced micro-CT","score":0.9169999957084656},{"id":"https://openalex.org/keywords/bony-defects","display_name":"bony defects","score":0.781000018119812},{"id":"https://openalex.org/keywords/in-vitro-angiogenesis-model","display_name":"in vitro angiogenesis model","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C60781801","wikidata":"https://www.wikidata.org/wiki/Q1424593","display_name":"Vasculogenesis","level":4,"score":0.7994729280471802},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.7204349040985107},{"id":"https://openalex.org/C2778271429","wikidata":"https://www.wikidata.org/wiki/Q1281049","display_name":"Neovascularization","level":3,"score":0.7132316827774048},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.6751886606216431},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.6341296434402466},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.6103600263595581},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36646509170532227},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.333779513835907},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.21815621852874756},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1584390103816986},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.13925904035568237},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.11860096454620361},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.09917417168617249},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D001847","descriptor_name":"Bone Diseases","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009389","descriptor_name":"Neovascularization, Pathologic","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009389","descriptor_name":"Neovascularization, Pathologic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009389","descriptor_name":"Neovascularization, Pathologic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D018919","descriptor_name":"Neovascularization, Physiologic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019919","descriptor_name":"Prosthesis Implantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020533","descriptor_name":"Angiogenesis Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1089/ten.teb.2008.0153","doi":"https://doi.org/10.1089/ten.teb.2008.0153","is_oa":false,"landing_page_url":"https://doi.org/10.1089/ten.teb.2008.0153","pdf_url":null,"source":{"id":"https://openalex.org/S13647896","display_name":"Tissue Engineering Part B Reviews","issn_l":"1937-3368","issn":["1937-3368","1937-3376"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering Part B: Reviews","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2761680","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2761680","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Eng Part B Rev","raw_type":"Text"},{"id":"pmid:18657028","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18657028","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue engineering. Part B, Reviews","raw_type":"Journal Article"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/69322","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2066/69322","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tissue Engineering. Part B: Reviews, 14, 3, pp. 295-306","raw_type":"Article / Letter to editor"},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/69322","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2066/69322","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tissue Engineering. Part B: Reviews, 14, 295 - 306","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2761680","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2761680","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Eng Part B Rev","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1466101954","display_name":"PROMOTION OF ALVEOLAR SOCKET HEALING WITH BIOPOLYMERS","funder_award_id":"R01DE015164","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G3201808254","display_name":"Biotechnology Research Training Grant","funder_award_id":"T32GM008362","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3483813164","display_name":"Medical Scientist Training Program","funder_award_id":"T32GM007330","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W100681333","https://openalex.org/W151723881","https://openalex.org/W182968378","https://openalex.org/W1559124628","https://openalex.org/W1562759933","https://openalex.org/W1600721209","https://openalex.org/W1843597170","https://openalex.org/W1868170796","https://openalex.org/W1871642698","https://openalex.org/W1969191752","https://openalex.org/W1972891104","https://openalex.org/W1975349241","https://openalex.org/W1979090321","https://openalex.org/W1980353103","https://openalex.org/W1981584086","https://openalex.org/W1985111027","https://openalex.org/W1987412665","https://openalex.org/W1989617588","https://openalex.org/W1995827857","https://openalex.org/W1997654945","https://openalex.org/W2000021550","https://openalex.org/W2001836057","https://openalex.org/W2005257891","https://openalex.org/W2010145494","https://openalex.org/W2014949387","https://openalex.org/W2025280242","https://openalex.org/W2028503910","https://openalex.org/W2034960421","https://openalex.org/W2038843643","https://openalex.org/W2038939848","https://openalex.org/W2039438407","https://openalex.org/W2044016094","https://openalex.org/W2049066868","https://openalex.org/W2052904083","https://openalex.org/W2053404797","https://openalex.org/W2054056891","https://openalex.org/W2055199717","https://openalex.org/W2056393111","https://openalex.org/W2060950200","https://openalex.org/W2063539948","https://openalex.org/W2068206834","https://openalex.org/W2068305230","https://openalex.org/W2074966558","https://openalex.org/W2075790920","https://openalex.org/W2076131961","https://openalex.org/W2077501711","https://openalex.org/W2079530892","https://openalex.org/W2092987783","https://openalex.org/W2094858086","https://openalex.org/W2096905762","https://openalex.org/W2097853442","https://openalex.org/W2108333200","https://openalex.org/W2110667326","https://openalex.org/W2112587095","https://openalex.org/W2113398281","https://openalex.org/W2120740945","https://openalex.org/W2120895512","https://openalex.org/W2124929268","https://openalex.org/W2126257976","https://openalex.org/W2137044802","https://openalex.org/W2137612350","https://openalex.org/W2143331663","https://openalex.org/W2147014530","https://openalex.org/W2151615254","https://openalex.org/W2152840072","https://openalex.org/W2158134118","https://openalex.org/W2161411549","https://openalex.org/W2174632235","https://openalex.org/W2244363876","https://openalex.org/W2398896513","https://openalex.org/W2417426465","https://openalex.org/W2467854611","https://openalex.org/W3148375785","https://openalex.org/W4242966102"],"related_works":["https://openalex.org/W2010949921","https://openalex.org/W2419129064","https://openalex.org/W4411605151","https://openalex.org/W3031848398","https://openalex.org/W1993765543","https://openalex.org/W4200093185","https://openalex.org/W2170810193","https://openalex.org/W2089339859","https://openalex.org/W1916533605","https://openalex.org/W1499209190"],"abstract_inverted_index":{"Vasculogenesis":[0],"and":[1,12,27,61,130,166],"angiogenesis":[2,172],"have":[3,146],"been":[4],"studied":[5],"for":[6,54,170,185,202],"decades":[7],"using":[8],"numerous":[9],"in":[10,13,24,41,71,78,164,167,180,188,206,209,218],"vitro":[11,165],"vivo":[14,79,168,207],"systems,":[15],"fulfilling":[16],"the":[17,21,46,52,62,66,77,102,151,181,197,203,219],"need":[18,53],"to":[19,28,82,86,116,149,154],"elucidate":[20],"mechanisms":[22],"involved":[23],"these":[25],"processes":[26],"test":[29],"potential":[30,198,217],"therapeutic":[31],"agents":[32],"that":[33],"inhibit":[34],"or":[35],"promote":[36],"neovascularization.":[37],"Bone":[38],"tissue":[39,157,190,223],"engineering":[40,158,191,224],"particular":[42],"has":[43,112],"benefited":[44],"from":[45],"application":[47],"of":[48,68,75,92,101,108,121,125,183,199,205,221],"proangiogenic":[49],"strategies,":[50],"considering":[51],"an":[55,155],"adequate":[56],"vascular":[57,104,132,152],"supply":[58],"during":[59],"healing":[60,140],"challenges":[63],"associated":[64],"with":[65],"vascularization":[67],"scaffolds":[69],"implanted":[70,156],"vivo.":[72],"Conventional":[73],"methods":[74],"assessing":[76],"angiogenic":[80],"response":[81,153],"tissue-engineered":[83],"constructs":[84],"tend":[85],"rely":[87],"on":[88],"a":[89,118],"two-dimensional":[90],"assessment":[91],"microvessel":[93],"density":[94],"within":[95,139],"representative":[96],"histological":[97],"sections":[98],"without":[99],"elaboration":[100],"true":[103],"tree.":[105],"The":[106],"introduction":[107],"microcomputed":[109],"tomography":[110],"(micro-CT)":[111],"recently":[113],"allowed":[114],"investigators":[115],"obtain":[117],"diverse":[119],"range":[120],"high-resolution,":[122],"three-dimensional":[123],"characterization":[124],"structures,":[126],"including":[127],"renal,":[128],"coronary,":[129],"hepatic":[131],"networks,":[133],"as":[134,136],"well":[135],"bone":[137,189,222],"formation":[138],"defects.":[141],"To":[142],"date,":[143],"few":[144],"studies":[145],"utilized":[147],"micro-CT":[148,184,201],"study":[150,195],"scaffold.":[159],"In":[160],"this":[161],"paper,":[162],"conventional":[163],"models":[169],"studying":[171],"will":[173],"be":[174],"discussed,":[175],"followed":[176],"by":[177],"recent":[178],"developments":[179],"use":[182],"vessel":[186],"imaging":[187],"research.":[192],"A":[193],"new":[194],"demonstrating":[196],"contrast-enhanced":[200],"evaluation":[204,220],"neovascularization":[208],"bony":[210],"defects":[211],"is":[212],"described,":[213],"which":[214],"offers":[215],"significant":[216],"constructs.":[225]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}