{"id":"https://openalex.org/W2140355269","doi":"https://doi.org/10.1083/jcb.59.3.643","title":"THE FINE STRUCTURE AND IMMUNOLOGICAL LABELING OF THE ACHROMATIC MITOTIC APPARATUS AFTER DISRUPTION OF CELL MEMBRANES","display_name":"THE FINE STRUCTURE AND IMMUNOLOGICAL LABELING OF THE ACHROMATIC MITOTIC APPARATUS AFTER DISRUPTION OF CELL MEMBRANES","publication_year":1973,"publication_date":"1973-12-01","ids":{"openalex":"https://openalex.org/W2140355269","doi":"https://doi.org/10.1083/jcb.59.3.643","mag":"2140355269","pmid":"https://pubmed.ncbi.nlm.nih.gov/4761334","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2109105"},"language":"en","primary_location":{"id":"doi:10.1083/jcb.59.3.643","doi":"https://doi.org/10.1083/jcb.59.3.643","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.59.3.643","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2109105","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053846385","display_name":"Samuel Dales","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel Dales","raw_affiliation_strings":["From the Department of Cytobiology, The Public Health Research Institute of the City of New York, Inc., New York 10016 and the Department of Urology, Columbia University College of Physicians and Surgeons, New York 10032"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cytobiology, The Public Health Research Institute of the City of New York, Inc., New York 10016 and the Department of Urology, Columbia University College of Physicians and Surgeons, New York 10032","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109861548","display_name":"Konrad C. Hsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Konrad C. Hsu","raw_affiliation_strings":["From the Department of Cytobiology, The Public Health Research Institute of the City of New York, Inc., New York 10016 and the Department of Urology, Columbia University College of Physicians and Surgeons, New York 10032"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cytobiology, The Public Health Research Institute of the City of New York, Inc., New York 10016 and the Department of Urology, Columbia University College of Physicians and Surgeons, New York 10032","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113575529","display_name":"Ariaki Nagayama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ariaki Nagayama","raw_affiliation_strings":["From the Department of Cytobiology, The Public Health Research Institute of the City of New York, Inc., New York 10016 and the Department of Urology, Columbia University College of Physicians and Surgeons, New York 10032"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cytobiology, The Public Health Research Institute of the City of New York, Inc., New York 10016 and the Department of Urology, Columbia University College of Physicians and Surgeons, New York 10032","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I78577930"],"apc_list":null,"apc_paid":null,"fwci":1.3425,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.7791447,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"59","issue":"3","first_page":"643","last_page":"660"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microtubules","display_name":"microtubules","score":0.9110000133514404},{"id":"https://openalex.org/keywords/tubulin","display_name":"tubulin","score":0.8259999752044678},{"id":"https://openalex.org/keywords/paracrystals","display_name":"paracrystals","score":0.8420000076293945},{"id":"https://openalex.org/keywords/vinblastine","display_name":"vinblastine","score":0.7730000019073486},{"id":"https://openalex.org/keywords/membrane-damage","display_name":"membrane damage","score":0.8339999914169312},{"id":"https://openalex.org/keywords/nonionic-detergents","display_name":"nonionic detergents","score":0.8489999771118164},{"id":"https://openalex.org/keywords/immunoperoxidase-labeling","display_name":"immunoperoxidase labeling","score":0.9120000004768372},{"id":"https://openalex.org/keywords/centrioles","display_name":"centrioles","score":0.7490000128746033},{"id":"https://openalex.org/keywords/nuclear-pore-complex","display_name":"nuclear pore complex","score":0.9190000295639038},{"id":"https://openalex.org/keywords/annulate-lamellae","display_name":"annulate lamellae","score":0.9909999966621399},{"id":"https://openalex.org/keywords/hela-cells","display_name":"HeLa cells","score":0.8669999837875366},{"id":"https://openalex.org/keywords/l-cells","display_name":"L cells","score":0.8410000205039978},{"id":"https://openalex.org/keywords/immunogold-labeling","display_name":"immunogold labeling","score":0.4429999887943268}],"concepts":[{"id":"https://openalex.org/C168240541","wikidata":"https://www.wikidata.org/wiki/Q45948","display_name":"Organelle","level":2,"score":0.7362433671951294},{"id":"https://openalex.org/C48342290","wikidata":"https://www.wikidata.org/wiki/Q178355","display_name":"Centriole","level":3,"score":0.6952527761459351},{"id":"https://openalex.org/C20418707","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule","level":2,"score":0.6910080313682556},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6903324127197266},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5938229560852051},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.5812427401542664},{"id":"https://openalex.org/C2776095844","wikidata":"https://www.wikidata.org/wiki/Q903666","display_name":"Colcemid","level":3,"score":0.5334660410881042},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5244724750518799},{"id":"https://openalex.org/C93877712","wikidata":"https://www.wikidata.org/wiki/Q132560","display_name":"Electron microscope","level":2,"score":0.5107932090759277},{"id":"https://openalex.org/C2778319317","wikidata":"https://www.wikidata.org/wiki/Q22327449","display_name":"Ferritin","level":2,"score":0.48921990394592285},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.4667295217514038},{"id":"https://openalex.org/C87555872","wikidata":"https://www.wikidata.org/wiki/Q3141316","display_name":"Ultrastructure","level":2,"score":0.4466443955898285},{"id":"https://openalex.org/C119062480","wikidata":"https://www.wikidata.org/wiki/Q83181","display_name":"Golgi apparatus","level":3,"score":0.44503697752952576},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.3232290744781494},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3169861435890198},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.13289836049079895},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000918","descriptor_name":"Antibody Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001666","descriptor_name":"Binding Sites, Antibody","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002463","descriptor_name":"Cell Membrane Permeability","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002498","descriptor_name":"Centrifugation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003902","descriptor_name":"Detergents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005293","descriptor_name":"Ferritins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007106","descriptor_name":"Immune Sera","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007739","descriptor_name":"L Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008870","descriptor_name":"Microtubules","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008870","descriptor_name":"Microtubules","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008938","descriptor_name":"Mitosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009940","descriptor_name":"Organoids","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009940","descriptor_name":"Organoids","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010544","descriptor_name":"Peroxidases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011132","descriptor_name":"Polyribosomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014747","descriptor_name":"Vinblastine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1083/jcb.59.3.643","doi":"https://doi.org/10.1083/jcb.59.3.643","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.59.3.643","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Cell Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:914028","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2109105","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2109105","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2109105","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},{"id":"pmid:4761334","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4761334","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.281.5338","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.281.5338","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/32/9b/J_Cell_Biol_1973_Dec_1_59(3)_643-660.tar.gz","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:914028","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2109105","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.4043000042438507,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1495060818","https://openalex.org/W1852389677","https://openalex.org/W1930761012","https://openalex.org/W1970628389","https://openalex.org/W1976019639","https://openalex.org/W1977702285","https://openalex.org/W1982720718","https://openalex.org/W2017531848","https://openalex.org/W2025743844","https://openalex.org/W2026166634","https://openalex.org/W2033271305","https://openalex.org/W2038647552","https://openalex.org/W2044966306","https://openalex.org/W2046171723","https://openalex.org/W2055184231","https://openalex.org/W2083898337","https://openalex.org/W2089682350","https://openalex.org/W2091654676","https://openalex.org/W2096475248","https://openalex.org/W2119079190","https://openalex.org/W2340203744","https://openalex.org/W2765493213"],"related_works":["https://openalex.org/W7095215499","https://openalex.org/W2052341456","https://openalex.org/W2003423414","https://openalex.org/W2467585098","https://openalex.org/W1974669593","https://openalex.org/W2081929054","https://openalex.org/W2396522587","https://openalex.org/W2000493156","https://openalex.org/W2021692957","https://openalex.org/W7073810034"],"abstract_inverted_index":{"After":[0],"treatment":[1],"of":[2,12,22,29,51,53,57,62,67,75,105,111,118,133,142,156,160,167,175,182,194],"HeLa":[3],"and":[4,45,95,144,177,187],"L":[5],"cells":[6],"with":[7,31,49,217],"vinblastine":[8],"sulfate":[9],"the":[10,96,128,131,140,157,162,173,180,183,188,192,195],"material":[11],"microtubules":[13,47],"(tubulin)":[14],"was":[15,122,152,169,208],"reorganized":[16],"into":[17],"(a)":[18],"large":[19],"paracrystals":[20],"(PC)":[21],"tightly":[23],"packed":[24],"tubules;":[25],"(b)":[26],"smaller":[27],"aggregates":[28,146],"tubules":[30],"greater":[32],"diameter":[33],"whose":[34],"walls":[35],"are":[36],"constituted":[37],"from":[38],"well":[39],"defined,":[40],"helically":[41],"arranged":[42],"morphological":[43],"subunits;":[44],"(c)":[46],"associated":[48],"helices":[50],"polyribosomes":[52],"uniform":[54],"size.":[55],"All":[56],"these":[58,198],"structures":[59],"survived":[60],"disruption":[61,120],"cellular":[63],"membranes":[64,76],"by":[65,107,154],"means":[66,155],"a":[68,72,79,103,116],"nonionic":[69],"detergent.":[70],"Following":[71],"thorough":[73],"stripping":[74],"there":[77],"remained":[78],"subcellular":[80],"fraction":[81],"sedimenting":[82],"at":[83,139],"1,500":[84],"g":[85],"for":[86],"15":[87],"min,":[88],"in":[89,127,172,205,213],"which":[90],"were":[91],"contained":[92],"nuclei,":[93],"centrioles,":[94],"above":[97],"mentioned":[98],"microtubular":[99],"elements,":[100],"maintained":[101],"as":[102],"complex":[104,186],"organelles":[106,199],"an":[108],"interconnecting":[109],"network":[110],"80":[112],"A":[113,164],"microfibrils.":[114],"As":[115],"result":[117,151],"membrane":[119],"it":[121],"possible":[123],"to":[124],"localize":[125],"precisely":[126],"electron":[129],"microscope":[130],"binding":[132],"ferritin":[134,168],"antibody":[135],"conjugates.":[136],"Specific":[137],"labeling":[138,161],"surface":[141],"PC":[143],"microtubule":[145],"could":[147],"be":[148],"demonstrated.":[149],"This":[150],"substantiated":[153],"immunoperoxidase":[158],"method":[159],"PC.":[163],"concentrated":[165],"deposit":[166],"also":[170,209],"found":[171],"vicinity":[174],"centrioles":[176],"related":[178],"structures,":[179],"annuli":[181],"nuclear":[184],"pore":[185],"annulate":[189],"lamellae.":[190],"However,":[191],"specificity":[193],"label":[196],"on":[197,211],"remains":[200],"questionable":[201],"because":[202],"ferritin,":[203],"albeit":[204],"lower":[206],"concentration,":[207],"present":[210],"them":[212],"control":[214],"preparations":[215],"reacted":[216],"preimmune":[218],"sera.":[219]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}