{"id":"https://openalex.org/W2140106525","doi":"https://doi.org/10.1074/mcp.m114.040352","title":"Quantitative Phosphoproteomics of the Ataxia Telangiectasia-Mutated (ATM) and Ataxia Telangiectasia-Mutated and Rad3-related (ATR) Dependent DNA Damage Response in Arabidopsis thaliana*","display_name":"Quantitative Phosphoproteomics of the Ataxia Telangiectasia-Mutated (ATM) and Ataxia Telangiectasia-Mutated and Rad3-related (ATR) Dependent DNA Damage Response in Arabidopsis thaliana*","publication_year":2015,"publication_date":"2015-01-05","ids":{"openalex":"https://openalex.org/W2140106525","doi":"https://doi.org/10.1074/mcp.m114.040352","mag":"2140106525","pmid":"https://pubmed.ncbi.nlm.nih.gov/25561503","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4349977"},"language":"en","primary_location":{"id":"doi:10.1074/mcp.m114.040352","doi":"https://doi.org/10.1074/mcp.m114.040352","is_oa":true,"landing_page_url":"https://doi.org/10.1074/mcp.m114.040352","pdf_url":null,"source":{"id":"https://openalex.org/S104550190","display_name":"Molecular & Cellular Proteomics","issn_l":"1535-9476","issn":["1535-9476","1535-9484"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular & Cellular Proteomics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/mcp.m114.040352","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067625368","display_name":"Elisabeth Roitinger","orcid":"https://orcid.org/0000-0002-3405-7801","observed_orcids":["https://orcid.org/0000-0002-3405-7801"]},"institutions":[{"id":"https://openalex.org/I125523173","display_name":"Institute of Molecular Biotechnology","ror":"https://ror.org/01zqrxf85","country_code":"AT","type":"facility","lineage":["https://openalex.org/I125523173","https://openalex.org/I138211613"]},{"id":"https://openalex.org/I195525897","display_name":"Research Institute of Molecular Pathology","ror":"https://ror.org/02c5jsm26","country_code":"AT","type":"facility","lineage":["https://openalex.org/I195525897"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Elisabeth Roitinger","raw_affiliation_strings":["From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria; \u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria;","From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria","\u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria; \u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria;","institution_ids":["https://openalex.org/I125523173","https://openalex.org/I195525897"]},{"raw_affiliation_string":"From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria","institution_ids":["https://openalex.org/I195525897"]},{"raw_affiliation_string":"\u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria","institution_ids":["https://openalex.org/I125523173"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Manuel Hofer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I2802916955","display_name":"Max Perutz Labs","ror":"https://ror.org/05cz70a34","country_code":"AT","type":"facility","lineage":["https://openalex.org/I129774422","https://openalex.org/I2802916955"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Manuel Hofer","raw_affiliation_strings":["\u00a7Department of Chromosome Biology, Max F. Perutz Laboratories, University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00a7Department of Chromosome Biology, Max F. Perutz Laboratories, University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I2802916955"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070000759","display_name":"Thomas K\u00f6cher","orcid":"https://orcid.org/0000-0003-0827-1457","observed_orcids":["https://orcid.org/0000-0003-0827-1457"]},"institutions":[{"id":"https://openalex.org/I195525897","display_name":"Research Institute of Molecular Pathology","ror":"https://ror.org/02c5jsm26","country_code":"AT","type":"facility","lineage":["https://openalex.org/I195525897"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Thomas K\u00f6cher","raw_affiliation_strings":["From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria","institution_ids":["https://openalex.org/I195525897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002702735","display_name":"Peter Pichler","orcid":"https://orcid.org/0000-0001-8340-0197","observed_orcids":["https://orcid.org/0000-0001-8340-0197"]},"institutions":[{"id":"https://openalex.org/I125523173","display_name":"Institute of Molecular Biotechnology","ror":"https://ror.org/01zqrxf85","country_code":"AT","type":"facility","lineage":["https://openalex.org/I125523173","https://openalex.org/I138211613"]},{"id":"https://openalex.org/I195525897","display_name":"Research Institute of Molecular Pathology","ror":"https://ror.org/02c5jsm26","country_code":"AT","type":"facility","lineage":["https://openalex.org/I195525897"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Peter Pichler","raw_affiliation_strings":["From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria; \u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria;","From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria","\u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria; \u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria;","institution_ids":["https://openalex.org/I125523173","https://openalex.org/I195525897"]},{"raw_affiliation_string":"From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria","institution_ids":["https://openalex.org/I195525897"]},{"raw_affiliation_string":"\u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria","institution_ids":["https://openalex.org/I125523173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023139971","display_name":"Maria Novatchkova","orcid":"https://orcid.org/0000-0002-8462-7171","observed_orcids":["https://orcid.org/0000-0002-8462-7171"]},"institutions":[{"id":"https://openalex.org/I125523173","display_name":"Institute of Molecular Biotechnology","ror":"https://ror.org/01zqrxf85","country_code":"AT","type":"facility","lineage":["https://openalex.org/I125523173","https://openalex.org/I138211613"]},{"id":"https://openalex.org/I195525897","display_name":"Research Institute of Molecular Pathology","ror":"https://ror.org/02c5jsm26","country_code":"AT","type":"facility","lineage":["https://openalex.org/I195525897"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Maria Novatchkova","raw_affiliation_strings":["From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria; \u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria;","From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria","\u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria; \u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria;","institution_ids":["https://openalex.org/I125523173","https://openalex.org/I195525897"]},{"raw_affiliation_string":"From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria","institution_ids":["https://openalex.org/I195525897"]},{"raw_affiliation_string":"\u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria","institution_ids":["https://openalex.org/I125523173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011865860","display_name":"Jianhua Yang","orcid":"https://orcid.org/0000-0002-6873-7653","observed_orcids":["https://orcid.org/0000-0002-6873-7653"]},"institutions":[{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jianhua Yang","raw_affiliation_strings":["\u2016School of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u2016School of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK","institution_ids":["https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064638553","display_name":"Peter Schl\u00f6gelhofer","orcid":"https://orcid.org/0000-0002-0909-3587","observed_orcids":["https://orcid.org/0000-0002-0909-3587"]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I2802916955","display_name":"Max Perutz Labs","ror":"https://ror.org/05cz70a34","country_code":"AT","type":"facility","lineage":["https://openalex.org/I129774422","https://openalex.org/I2802916955"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Peter Schl\u00f6gelhofer","raw_affiliation_strings":["\u00a7Department of Chromosome Biology, Max F. Perutz Laboratories, University of Vienna, Vienna, Austria; Karl.Mechtler@imp.ac.at Peter.Schloegelhofer@univie.ac.at","\u00a7Department of Chromosome Biology, Max F. Perutz Laboratories, University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00a7Department of Chromosome Biology, Max F. Perutz Laboratories, University of Vienna, Vienna, Austria; Karl.Mechtler@imp.ac.at Peter.Schloegelhofer@univie.ac.at","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I2802916955"]},{"raw_affiliation_string":"\u00a7Department of Chromosome Biology, Max F. Perutz Laboratories, University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I2802916955"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014342884","display_name":"Karl Mechtler","orcid":"https://orcid.org/0000-0002-3392-9946","observed_orcids":["https://orcid.org/0000-0002-3392-9946"]},"institutions":[{"id":"https://openalex.org/I125523173","display_name":"Institute of Molecular Biotechnology","ror":"https://ror.org/01zqrxf85","country_code":"AT","type":"facility","lineage":["https://openalex.org/I125523173","https://openalex.org/I138211613"]},{"id":"https://openalex.org/I195525897","display_name":"Research Institute of Molecular Pathology","ror":"https://ror.org/02c5jsm26","country_code":"AT","type":"facility","lineage":["https://openalex.org/I195525897"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Karl Mechtler","raw_affiliation_strings":["From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria; \u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria; Karl.Mechtler@imp.ac.at Peter.Schloegelhofer@univie.ac.at","From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria","\u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria; \u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria; Karl.Mechtler@imp.ac.at Peter.Schloegelhofer@univie.ac.at","institution_ids":["https://openalex.org/I125523173","https://openalex.org/I195525897"]},{"raw_affiliation_string":"From the \u2021Institute of Molecular Pathology (IMP), Vienna, Austria","institution_ids":["https://openalex.org/I195525897"]},{"raw_affiliation_string":"\u00b6Institute of Molecular Biotechnology (IMBA), Vienna, Austria","institution_ids":["https://openalex.org/I125523173"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5014342884","https://openalex.org/A5064638553"],"corresponding_institution_ids":["https://openalex.org/I125523173","https://openalex.org/I129774422","https://openalex.org/I195525897","https://openalex.org/I2802916955"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":1786,"currency":"EUR","value_usd":1926},"fwci":8.8335,"has_fulltext":false,"cited_by_count":224,"citation_normalized_percentile":{"value":0.99261471,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"14","issue":"3","first_page":"556","last_page":"571"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.5371000170707703,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.5371000170707703,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.4375,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atm","display_name":"ATM","score":0.7390000224113464},{"id":"https://openalex.org/keywords/attenuated-total-reflectance","display_name":"ATR","score":0.9959999918937683},{"id":"https://openalex.org/keywords/dna-damage-response","display_name":"DNA damage response","score":0.9259999990463257},{"id":"https://openalex.org/keywords/phosphoproteomics","display_name":"phosphoproteomics","score":0.8360000252723694},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.9570000171661377},{"id":"https://openalex.org/keywords/protein-phosphorylation","display_name":"protein phosphorylation","score":0.7710000276565552},{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.8420000076293945},{"id":"https://openalex.org/keywords/ionizing-radiation","display_name":"ionizing radiation","score":0.7279999852180481},{"id":"https://openalex.org/keywords/cell-cycle-checkpoints","display_name":"cell cycle checkpoints","score":0.5809999704360962},{"id":"https://openalex.org/keywords/chromatin-remodeling","display_name":"chromatin remodeling","score":0.9200000166893005},{"id":"https://openalex.org/keywords/dna-replication","display_name":"DNA replication","score":0.7860000133514404},{"id":"https://openalex.org/keywords/meiosis","display_name":"meiosis","score":0.8659999966621399},{"id":"https://openalex.org/keywords/phosphopeptide-enrichment","display_name":"phosphopeptide enrichment","score":0.8109999895095825}],"concepts":[{"id":"https://openalex.org/C2779486608","wikidata":"https://www.wikidata.org/wiki/Q387082","display_name":"Ataxia-telangiectasia","level":4,"score":0.8740097284317017},{"id":"https://openalex.org/C2775988993","wikidata":"https://www.wikidata.org/wiki/Q158695","display_name":"Arabidopsis thaliana","level":4,"score":0.616431713104248},{"id":"https://openalex.org/C6675166","wikidata":"https://www.wikidata.org/wiki/Q7187538","display_name":"Phosphoproteomics","level":5,"score":0.6019415855407715},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.49869441986083984},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4517759680747986},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3832798898220062},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.38315388560295105},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3481863737106323},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.21933278441429138},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14652296900749207},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.09262341260910034},{"id":"https://openalex.org/C87325107","wikidata":"https://www.wikidata.org/wiki/Q7251493","display_name":"Protein phosphorylation","level":4,"score":0.0},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018744","descriptor_name":"DNA, Plant","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D064007","descriptor_name":"Ataxia Telangiectasia Mutated Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D064007","descriptor_name":"Ataxia Telangiectasia Mutated Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1074/mcp.m114.040352","doi":"https://doi.org/10.1074/mcp.m114.040352","is_oa":true,"landing_page_url":"https://doi.org/10.1074/mcp.m114.040352","pdf_url":null,"source":{"id":"https://openalex.org/S104550190","display_name":"Molecular & Cellular Proteomics","issn_l":"1535-9476","issn":["1535-9476","1535-9484"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular & Cellular Proteomics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4349977","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4349977","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Cell Proteomics","raw_type":"Text"},{"id":"pmid:25561503","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25561503","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular & cellular proteomics : MCP","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.993.9239","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.993.9239","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.mcponline.org/content/14/3/556.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1074/mcp.m114.040352","doi":"https://doi.org/10.1074/mcp.m114.040352","is_oa":true,"landing_page_url":"https://doi.org/10.1074/mcp.m114.040352","pdf_url":null,"source":{"id":"https://openalex.org/S104550190","display_name":"Molecular & Cellular Proteomics","issn_l":"1535-9476","issn":["1535-9476","1535-9484"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular & Cellular Proteomics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":96,"referenced_works":["https://openalex.org/W1547329255","https://openalex.org/W1558044876","https://openalex.org/W1964692421","https://openalex.org/W1968126063","https://openalex.org/W1970039616","https://openalex.org/W1970544448","https://openalex.org/W1970965314","https://openalex.org/W1973466091","https://openalex.org/W1977088495","https://openalex.org/W1979705230","https://openalex.org/W1982471333","https://openalex.org/W1982553328","https://openalex.org/W1985775217","https://openalex.org/W1989665806","https://openalex.org/W1995630548","https://openalex.org/W1996238383","https://openalex.org/W1998738689","https://openalex.org/W2000042427","https://openalex.org/W2002900187","https://openalex.org/W2006189460","https://openalex.org/W2006303829","https://openalex.org/W2007942027","https://openalex.org/W2008743975","https://openalex.org/W2010706742","https://openalex.org/W2011437112","https://openalex.org/W2011981585","https://openalex.org/W2022539205","https://openalex.org/W2023620387","https://openalex.org/W2029388127","https://openalex.org/W2031922425","https://openalex.org/W2033461532","https://openalex.org/W2037117761","https://openalex.org/W2037199116","https://openalex.org/W2037728125","https://openalex.org/W2038154009","https://openalex.org/W2038801176","https://openalex.org/W2040860750","https://openalex.org/W2043006824","https://openalex.org/W2043895957","https://openalex.org/W2050608484","https://openalex.org/W2052141890","https://openalex.org/W2058223290","https://openalex.org/W2061471901","https://openalex.org/W2063186742","https://openalex.org/W2067539799","https://openalex.org/W2069682761","https://openalex.org/W2071609491","https://openalex.org/W2073101700","https://openalex.org/W2074677426","https://openalex.org/W2080842750","https://openalex.org/W2082078734","https://openalex.org/W2088998472","https://openalex.org/W2089130084","https://openalex.org/W2093611899","https://openalex.org/W2099278991","https://openalex.org/W2102334472","https://openalex.org/W2104922431","https://openalex.org/W2105543948","https://openalex.org/W2107491970","https://openalex.org/W2107495112","https://openalex.org/W2107835389","https://openalex.org/W2109960177","https://openalex.org/W2110817748","https://openalex.org/W2113584758","https://openalex.org/W2114299756","https://openalex.org/W2116052270","https://openalex.org/W2116786105","https://openalex.org/W2116791893","https://openalex.org/W2118514901","https://openalex.org/W2126531920","https://openalex.org/W2128397247","https://openalex.org/W2130057402","https://openalex.org/W2132636255","https://openalex.org/W2133564336","https://openalex.org/W2134314409","https://openalex.org/W2135325774","https://openalex.org/W2135897785","https://openalex.org/W2139069348","https://openalex.org/W2140886363","https://openalex.org/W2141575449","https://openalex.org/W2145595952","https://openalex.org/W2145820743","https://openalex.org/W2150756743","https://openalex.org/W2152287977","https://openalex.org/W2153047151","https://openalex.org/W2157918066","https://openalex.org/W2161874024","https://openalex.org/W2162103775","https://openalex.org/W2166632909","https://openalex.org/W2169143176","https://openalex.org/W2169630006","https://openalex.org/W2171324188","https://openalex.org/W2325375737","https://openalex.org/W2414647037","https://openalex.org/W4243001760","https://openalex.org/W7099724253"],"related_works":["https://openalex.org/W7098202813","https://openalex.org/W2112651502","https://openalex.org/W2611522287","https://openalex.org/W2324892617","https://openalex.org/W3105238532","https://openalex.org/W2110817748","https://openalex.org/W2062686677","https://openalex.org/W2007942027","https://openalex.org/W2144793302","https://openalex.org/W2415445337"],"abstract_inverted_index":{"The":[0,38,101],"reversible":[1],"phosphorylation":[2,27],"of":[3,20,35,63,74,81,144,164],"proteins":[4,166],"on":[5],"serine,":[6],"threonine,":[7],"and":[8,33,46,49,79,116,125,135,149,169,178,187,194,203,211,217,219],"tyrosine":[9],"residues":[10],"is":[11],"an":[12],"important":[13],"biological":[14],"regulatory":[15],"mechanism.":[16],"In":[17],"the":[18,31,72,142],"context":[19],"genome":[21],"integrity,":[22],"signaling":[23],"cascades":[24],"driven":[25],"by":[26,160],"are":[28,52,67],"crucial":[29],"for":[30,60,121,133,140,197],"coordination":[32],"regulation":[34,80],"DNA":[36,64,82,95,215],"repair.":[37],"two":[39],"serine/threonine":[40],"protein":[41],"kinases":[42],"ataxia":[43],"telangiectasia-mutated":[44,48],"(ATM)":[45],"Ataxia":[47],"Rad3-related":[50],"(ATR)":[51],"key":[53],"factors":[54],"in":[55,98,206,214,222],"this":[56],"process,":[57],"each":[58],"specific":[59],"different":[61],"kinds":[62],"lesions.":[65],"They":[66],"conserved":[68],"across":[69],"eukaryotes,":[70],"mediating":[71],"activation":[73],"cell-cycle":[75],"checkpoints,":[76],"chromatin":[77,207],"modifications,":[78],"repair":[83,97],"proteins.":[84],"We":[85,184],"designed":[86],"a":[87],"novel":[88,188],"mass":[89],"spectrometry-based":[90],"phosphoproteomics":[91],"approach":[92],"to":[93],"study":[94],"damage":[96],"Arabidopsis":[99],"thaliana.":[100],"protocol":[102],"combines":[103],"filter":[104],"aided":[105],"sample":[106],"preparation,":[107],"immobilized":[108],"metal":[109,112],"affinity":[110,114],"chromatography,":[111,115],"oxide":[113],"strong":[117],"cation":[118],"exchange":[119],"chromatography":[120],"phosphopeptide":[122],"generation,":[123],"enrichment,":[124],"separation.":[126],"Isobaric":[127],"labeling":[128],"employing":[129],"iTRAQ":[130],"(isobaric":[131],"tags":[132],"relative":[134],"absolute":[136],"quantitation)":[137],"was":[138],"used":[139],"profiling":[141],"phosphoproteome":[143],"atm":[145],"atr":[146],"double":[147],"mutants":[148],"wild":[150],"type":[151],"plants":[152],"under":[153],"either":[154],"regular":[155],"growth":[156],"conditions":[157],"or":[158],"challenged":[159],"irradiation.":[161],"A":[162],"total":[163],"10,831":[165],"were":[167,173],"identified":[168,185],"15,445":[170],"unique":[171],"phosphopeptides":[172],"quantified,":[174],"containing":[175],"134":[176],"up-":[177],"38":[179],"down-regulated":[180],"ATM/ATR":[181,189],"dependent":[182],"phosphopeptides.":[183],"known":[186],"targets":[190],"such":[191],"as":[192],"LIG4":[193],"MRE11":[195],"(needed":[196],"resistance":[198],"against":[199],"ionizing":[200],"radiation),":[201],"PIE1":[202],"SDG26":[204],"(implicated":[205,213],"remodeling),":[208],"PCNA1,":[209],"WAPL,":[210],"PDS5":[212],"replication),":[216],"ASK1":[218],"HTA10":[220],"(involved":[221],"meiosis).":[223]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":21},{"year":2022,"cited_by_count":22},{"year":2021,"cited_by_count":22},{"year":2020,"cited_by_count":22},{"year":2019,"cited_by_count":27},{"year":2018,"cited_by_count":23},{"year":2017,"cited_by_count":26},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}