{"id":"https://openalex.org/W2139882380","doi":"https://doi.org/10.1046/j.1460-9568.2003.02463.x","title":"Dopamine gating of forebrain neural ensembles","display_name":"Dopamine gating of forebrain neural ensembles","publication_year":2003,"publication_date":"2003-01-31","ids":{"openalex":"https://openalex.org/W2139882380","doi":"https://doi.org/10.1046/j.1460-9568.2003.02463.x","mag":"2139882380","pmid":"https://pubmed.ncbi.nlm.nih.gov/12581161"},"language":"en","primary_location":{"id":"doi:10.1046/j.1460-9568.2003.02463.x","doi":"https://doi.org/10.1046/j.1460-9568.2003.02463.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1460-9568.2003.02463.x","pdf_url":null,"source":{"id":"https://openalex.org/S171130801","display_name":"European Journal of Neuroscience","issn_l":"0953-816X","issn":["0953-816X","1460-9568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Neuroscience","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2139882380"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021135343","display_name":"Patricio O\u2019Donnell","orcid":"https://orcid.org/0000-0001-7788-624X","observed_orcids":["https://orcid.org/0000-0001-7788-624X"]},"institutions":[{"id":"https://openalex.org/I4405260259","display_name":"Albany Medical College","ror":"https://ror.org/03g66yt05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405259726","https://openalex.org/I4405260259"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Patricio O'Donnell","raw_affiliation_strings":["Center for Neuropharmacology & Neuroscience, Albany Medical College (MC-136), 47 New Scotland Ave, NY 12208, USA. odonnep@mail.amc.edu","Center for Neuropharmacology and Neuroscience, Albany Medical College MC-136, 47 New Scotland Ave, Albany, NY 12208, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neuropharmacology & Neuroscience, Albany Medical College (MC-136), 47 New Scotland Ave, NY 12208, USA. odonnep@mail.amc.edu","institution_ids":["https://openalex.org/I4405260259"]},{"raw_affiliation_string":"Center for Neuropharmacology and Neuroscience, Albany Medical College MC-136, 47 New Scotland Ave, Albany, NY 12208, USA","institution_ids":["https://openalex.org/I4405260259"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5021135343"],"corresponding_institution_ids":["https://openalex.org/I4405260259"],"apc_list":{"value":3560,"currency":"USD","value_usd":3560},"apc_paid":null,"fwci":1.987,"has_fulltext":false,"cited_by_count":259,"citation_normalized_percentile":{"value":0.8686606,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"17","issue":"3","first_page":"429","last_page":"435"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.482699990272522,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.482699990272522,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.4503999948501587,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.05649999901652336,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.9309999942779541},{"id":"https://openalex.org/keywords/dopamine-d1-receptor","display_name":"dopamine D1 receptor","score":0.9070000052452087},{"id":"https://openalex.org/keywords/dopamine-d2-receptor","display_name":"dopamine D2 receptor","score":1.0},{"id":"https://openalex.org/keywords/striatal-medium-spiny-neurons","display_name":"striatal medium spiny neurons","score":0.9589999914169312},{"id":"https://openalex.org/keywords/state-stabilization","display_name":"state stabilization","score":0.5130000114440918},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.7870000004768372},{"id":"https://openalex.org/keywords/signal-to-noise-ratio","display_name":"signal-to-noise ratio","score":0.9210000038146973},{"id":"https://openalex.org/keywords/postsynaptic-depolarization","display_name":"postsynaptic depolarization","score":0.8029999732971191}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.8268197178840637},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.7710263729095459},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.6450425982475281},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.5900596380233765},{"id":"https://openalex.org/C85714458","wikidata":"https://www.wikidata.org/wiki/Q17152690","display_name":"Medium spiny neuron","level":4,"score":0.5701848268508911},{"id":"https://openalex.org/C2779715522","wikidata":"https://www.wikidata.org/wiki/Q507027","display_name":"Forebrain","level":3,"score":0.5625015497207642},{"id":"https://openalex.org/C120069818","wikidata":"https://www.wikidata.org/wiki/Q415496","display_name":"Dopamine receptor","level":3,"score":0.5491582751274109},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.5484394431114197},{"id":"https://openalex.org/C194544171","wikidata":"https://www.wikidata.org/wiki/Q21105679","display_name":"Gating","level":2,"score":0.4391299784183502},{"id":"https://openalex.org/C44208683","wikidata":"https://www.wikidata.org/wiki/Q15335165","display_name":"Dopamine receptor D2","level":3,"score":0.4381178915500641},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4227471351623535},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.38593998551368713},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.370395302772522},{"id":"https://openalex.org/C2780062018","wikidata":"https://www.wikidata.org/wiki/Q1319792","display_name":"Striatum","level":3,"score":0.14122089743614197},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.10535022616386414},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008564","descriptor_name":"Membrane Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016548","descriptor_name":"Prosencephalon","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D016548","descriptor_name":"Prosencephalon","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1046/j.1460-9568.2003.02463.x","doi":"https://doi.org/10.1046/j.1460-9568.2003.02463.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1460-9568.2003.02463.x","pdf_url":null,"source":{"id":"https://openalex.org/S171130801","display_name":"European Journal of Neuroscience","issn_l":"0953-816X","issn":["0953-816X","1460-9568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmid:12581161","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12581161","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The European journal of neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.419.4557","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.419.4557","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.chaos.gwdg.de/~michael/CNS_course_2005/papers/Woergoetter/odonnel03.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1304699629","display_name":"Animal model of dual diagnosis","funder_award_id":"R01DA014020","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G4471809419","display_name":"Information processing in the nucleus accumbens","funder_award_id":"R01MH060131","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G4881765923","display_name":null,"funder_award_id":"MH57689","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":96,"referenced_works":["https://openalex.org/W1481369757","https://openalex.org/W1516646705","https://openalex.org/W1534301864","https://openalex.org/W1550372013","https://openalex.org/W1567533370","https://openalex.org/W1595473599","https://openalex.org/W1608548628","https://openalex.org/W1642699591","https://openalex.org/W1676571406","https://openalex.org/W1810663112","https://openalex.org/W1819927624","https://openalex.org/W1823057531","https://openalex.org/W1823940465","https://openalex.org/W1849626795","https://openalex.org/W1853766545","https://openalex.org/W1880531314","https://openalex.org/W1892194563","https://openalex.org/W1892379295","https://openalex.org/W1893239824","https://openalex.org/W1916165364","https://openalex.org/W1935461641","https://openalex.org/W1945424073","https://openalex.org/W1946022517","https://openalex.org/W1949141612","https://openalex.org/W1950553701","https://openalex.org/W1960542643","https://openalex.org/W1965657753","https://openalex.org/W1969751478","https://openalex.org/W1979080805","https://openalex.org/W1990186908","https://openalex.org/W1994483275","https://openalex.org/W1996762183","https://openalex.org/W2010139355","https://openalex.org/W2013032568","https://openalex.org/W2015701330","https://openalex.org/W2026181711","https://openalex.org/W2026306356","https://openalex.org/W2029474372","https://openalex.org/W2031170958","https://openalex.org/W2032243789","https://openalex.org/W2033382270","https://openalex.org/W2034776732","https://openalex.org/W2042650460","https://openalex.org/W2055523610","https://openalex.org/W2056198101","https://openalex.org/W2059378567","https://openalex.org/W2061138142","https://openalex.org/W2070735891","https://openalex.org/W2071944493","https://openalex.org/W2074748735","https://openalex.org/W2075370186","https://openalex.org/W2075831689","https://openalex.org/W2076434927","https://openalex.org/W2079276685","https://openalex.org/W2081637705","https://openalex.org/W2084680213","https://openalex.org/W2085505779","https://openalex.org/W2090375124","https://openalex.org/W2091322518","https://openalex.org/W2093289513","https://openalex.org/W2096178360","https://openalex.org/W2101948750","https://openalex.org/W2103248466","https://openalex.org/W2111746164","https://openalex.org/W2111835674","https://openalex.org/W2112202162","https://openalex.org/W2120411894","https://openalex.org/W2124028047","https://openalex.org/W2125293846","https://openalex.org/W2126680030","https://openalex.org/W2127946577","https://openalex.org/W2128211763","https://openalex.org/W2129319957","https://openalex.org/W2135727783","https://openalex.org/W2136348943","https://openalex.org/W2139358036","https://openalex.org/W2141275460","https://openalex.org/W2143100380","https://openalex.org/W2145594774","https://openalex.org/W2146288322","https://openalex.org/W2152256837","https://openalex.org/W2153961293","https://openalex.org/W2154169426","https://openalex.org/W2156213901","https://openalex.org/W2160425673","https://openalex.org/W2165649338","https://openalex.org/W2169075810","https://openalex.org/W2184281849","https://openalex.org/W2245948004","https://openalex.org/W2257076861","https://openalex.org/W2411645165","https://openalex.org/W2441244614","https://openalex.org/W2471449461","https://openalex.org/W3150048212","https://openalex.org/W4238505877","https://openalex.org/W4319293045"],"related_works":["https://openalex.org/W648628993","https://openalex.org/W2057130185","https://openalex.org/W2000979942","https://openalex.org/W2116888010","https://openalex.org/W7096407093","https://openalex.org/W2103730850","https://openalex.org/W1981878280","https://openalex.org/W1893239824","https://openalex.org/W2109660229"],"abstract_inverted_index":{"Dopamine":[0],"may":[1,18,51],"exert":[2],"different":[3],"actions":[4,23],"depending":[5],"on":[6,47],"a":[7,128,151,158],"number":[8],"of":[9,45,58,61,161],"factors.":[10],"A":[11],"common":[12],"view":[13],"is":[14,87,125],"that":[15,81,89],"D1":[16,90],"receptors":[17,26,91],"be":[19,36,52,150],"responsible":[20],"for":[21],"excitatory":[22],"whereas":[24],"D2":[25,136],"are":[27],"involved":[28],"in":[29,55,120,130,154,157],"inhibitory":[30],"actions.":[31,85],"However,":[32],"this":[33,114],"position":[34],"cannot":[35],"reconciled":[37],"with":[38],"several":[39],"findings":[40],"indicating":[41],"otherwise.":[42],"The":[43,147],"role":[44],"dopamine":[46,84,116],"forebrain":[48],"neural":[49],"ensembles":[50],"better":[53],"understood":[54],"the":[56,62,140],"light":[57],"functional":[59],"states":[60,77,99],"system.":[63],"Pyramidal":[64],"cortical":[65],"neurons":[66,71],"and":[67,79,100,109],"striatal":[68],"medium":[69],"spiny":[70],"alternate":[72],"between":[73],"two":[74],"membrane":[75],"potential":[76],"('up'":[78],"'down')":[80],"could":[82],"shape":[83],"It":[86],"proposed":[88],"can":[92,117],"act":[93],"as":[94],"state-stabilizers":[95],"by":[96,105,127,135],"sustaining":[97],"up":[98],"thereby":[101],"facilitating":[102],"plasticity":[103],"mechanisms":[104],"providing":[106],"postsynaptic":[107],"depolarization":[108],"increasing":[110],"NMDA":[111],"function.":[112],"In":[113],"way,":[115],"sustain":[118],"activity":[119],"depolarized":[121],"units.":[122],"This":[123],"action":[124],"accompanied":[126],"decrease":[129],"cell":[131],"firing":[132],"(perhaps":[133],"mediated":[134],"receptors),":[137],"which":[138],"renders":[139],"cells":[141],"responsive":[142],"only":[143],"to":[144],"strong":[145],"stimuli.":[146],"result":[148],"would":[149],"net":[152],"increase":[153],"signal-to-noise":[155],"ratio":[156],"selected":[159],"assembly":[160],"neurons.":[162]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":16}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}