{"id":"https://openalex.org/W2139761802","doi":"https://doi.org/10.1172/jci112730","title":"Prevention of lethal murine graft versus host disease by treatment of donor cells with L-leucyl-L-leucine methyl ester.","display_name":"Prevention of lethal murine graft versus host disease by treatment of donor cells with L-leucyl-L-leucine methyl ester.","publication_year":1986,"publication_date":"1986-11-01","ids":{"openalex":"https://openalex.org/W2139761802","doi":"https://doi.org/10.1172/jci112730","mag":"2139761802","pmid":"https://pubmed.ncbi.nlm.nih.gov/3534002","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/423850"},"language":"en","primary_location":{"id":"doi:10.1172/jci112730","doi":"https://doi.org/10.1172/jci112730","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci112730","pdf_url":"http://www.jci.org/articles/view/112730/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jci.org/articles/view/112730/files/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047334007","display_name":"Michael R. Charley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094379","display_name":"University of Texas Health Science Center at Dallas","ror":"https://ror.org/00q16t150","country_code":"US","type":"education","lineage":["https://openalex.org/I4210094379"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Charley","raw_affiliation_strings":["Departments ofDermatology, Pathology, and the Rheumatic and Liver Units ofthe Department ofInternal Medicine , University of Texas Health Science Center , Dallas , Texas 75235","University of Texas, Southwestern Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments ofDermatology, Pathology, and the Rheumatic and Liver Units ofthe Department ofInternal Medicine , University of Texas Health Science Center , Dallas , Texas 75235","institution_ids":["https://openalex.org/I4210094379"]},{"raw_affiliation_string":"University of Texas, Southwestern Medical Center","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111817601","display_name":"Dwain L. Thiele","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094379","display_name":"University of Texas Health Science Center at Dallas","ror":"https://ror.org/00q16t150","country_code":"US","type":"education","lineage":["https://openalex.org/I4210094379"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D L Thiele","raw_affiliation_strings":["Departments ofDermatology, Pathology, and the Rheumatic and Liver Units ofthe Department ofInternal Medicine , University of Texas Health Science Center , Dallas , Texas 75235","Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments ofDermatology, Pathology, and the Rheumatic and Liver Units ofthe Department ofInternal Medicine , University of Texas Health Science Center , Dallas , Texas 75235","institution_ids":["https://openalex.org/I4210094379"]},{"raw_affiliation_string":"Internal Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048300448","display_name":"Michael Bennett","orcid":"https://orcid.org/0000-0002-2424-7257","observed_orcids":["https://orcid.org/0000-0002-2424-7257","https://orcid.org/0000-0003-1040-5186"]},"institutions":[{"id":"https://openalex.org/I4210094379","display_name":"University of Texas Health Science Center at Dallas","ror":"https://ror.org/00q16t150","country_code":"US","type":"education","lineage":["https://openalex.org/I4210094379"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Bennett","raw_affiliation_strings":["Departments ofDermatology, Pathology, and the Rheumatic and Liver Units ofthe Department ofInternal Medicine , University of Texas Health Science Center , Dallas , Texas 75235","University of Texas, Southwestern Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments ofDermatology, Pathology, and the Rheumatic and Liver Units ofthe Department ofInternal Medicine , University of Texas Health Science Center , Dallas , Texas 75235","institution_ids":["https://openalex.org/I4210094379"]},{"raw_affiliation_string":"University of Texas, Southwestern Medical Center","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043874873","display_name":"Peter E. Lipsky","orcid":"https://orcid.org/0000-0002-9287-1676","observed_orcids":["https://orcid.org/0000-0002-9287-1676"]},"institutions":[{"id":"https://openalex.org/I4210094379","display_name":"University of Texas Health Science Center at Dallas","ror":"https://ror.org/00q16t150","country_code":"US","type":"education","lineage":["https://openalex.org/I4210094379"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P E Lipsky","raw_affiliation_strings":["Departments ofDermatology, Pathology, and the Rheumatic and Liver Units ofthe Department ofInternal Medicine , University of Texas Health Science Center , Dallas , Texas 75235","University of Texas, Southwestern Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments ofDermatology, Pathology, and the Rheumatic and Liver Units ofthe Department ofInternal Medicine , University of Texas Health Science Center , Dallas , Texas 75235","institution_ids":["https://openalex.org/I4210094379"]},{"raw_affiliation_string":"University of Texas, Southwestern Medical Center","institution_ids":["https://openalex.org/I867280407"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5200,"currency":"USD","value_usd":5200},"apc_paid":null,"fwci":0.9736,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.7641328,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"78","issue":"5","first_page":"1415","last_page":"1420"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12900","display_name":"Organ and Tissue Transplantation Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/graft-versus-host-disease","display_name":"graft-versus-host disease","score":0.9359999895095825},{"id":"https://openalex.org/keywords/bone-marrow-transplantation","display_name":"bone marrow transplantation","score":0.953000009059906},{"id":"https://openalex.org/keywords/semiallogeneic-transplantation","display_name":"semiallogeneic transplantation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/alloimmunization","display_name":"alloimmunization","score":0.5899999737739563},{"id":"https://openalex.org/keywords/stem-cell-function","display_name":"stem cell function","score":0.7099999785423279},{"id":"https://openalex.org/keywords/erythropoiesis","display_name":"erythropoiesis","score":0.9660000205039978},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.47200000286102295}],"concepts":[{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.7578667998313904},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.6680235862731934},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5637837648391724},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5338431596755981},{"id":"https://openalex.org/C2779703530","wikidata":"https://www.wikidata.org/wiki/Q837174","display_name":"Erythropoiesis","level":3,"score":0.5309543013572693},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46484440565109253},{"id":"https://openalex.org/C2779972918","wikidata":"https://www.wikidata.org/wiki/Q1194520","display_name":"Graft-versus-host disease","level":3,"score":0.43177908658981323},{"id":"https://openalex.org/C124964019","wikidata":"https://www.wikidata.org/wiki/Q11616062","display_name":"Precursor cell","level":3,"score":0.42967402935028076},{"id":"https://openalex.org/C2908901283","wikidata":"https://www.wikidata.org/wiki/Q1194520","display_name":"Graft vs Host Reaction","level":4,"score":0.4270452857017517},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.40258339047431946},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.34543728828430176},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32088321447372437},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19389083981513977},{"id":"https://openalex.org/C2994180119","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Bone marrow transplantation","level":3,"score":0.19306612014770508},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1428922414779663},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.10161101818084717}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004151","descriptor_name":"Dipeptides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006085","descriptor_name":"Graft Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006086","descriptor_name":"Graft vs Host Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D016026","descriptor_name":"Bone Marrow Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017710","descriptor_name":"Lymphocyte Transfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1172/jci112730","doi":"https://doi.org/10.1172/jci112730","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci112730","pdf_url":"http://www.jci.org/articles/view/112730/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:423850","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/423850","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Invest","raw_type":"Text"},{"id":"pmid:3534002","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3534002","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical investigation","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1172/jci112730","doi":"https://doi.org/10.1172/jci112730","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci112730","pdf_url":"http://www.jci.org/articles/view/112730/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9789000153541565,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G337897660","display_name":null,"funder_award_id":"AI17363","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5744312998","display_name":"CUTANEOUS SCLEROSIS IN GRAFT-VS-HOST DISEASE","funder_award_id":"5k08am001348-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6573907204","display_name":null,"funder_award_id":"AM-9989 +","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7284175128","display_name":"IMMUNOLOGIC FUNCTION OF LIVER SINUSOIDAL CELLS","funder_award_id":"5k08am001251-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7390582304","display_name":"PROGRAM PROJECT IN LIVER DISEASES","funder_award_id":"5p01am019329-10","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139761802.pdf","grobid_xml":"https://content.openalex.org/works/W2139761802.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1494496956","https://openalex.org/W1497278722","https://openalex.org/W1499992835","https://openalex.org/W1513257937","https://openalex.org/W1523444015","https://openalex.org/W1547913407","https://openalex.org/W1575020750","https://openalex.org/W1608418211","https://openalex.org/W1748467151","https://openalex.org/W1972978214","https://openalex.org/W1985977074","https://openalex.org/W2015728820","https://openalex.org/W2021508653","https://openalex.org/W2037889111","https://openalex.org/W2050642909","https://openalex.org/W2074614649","https://openalex.org/W2081549017","https://openalex.org/W2096648897","https://openalex.org/W2317642686","https://openalex.org/W2336063495","https://openalex.org/W2403899300"],"related_works":["https://openalex.org/W291815943","https://openalex.org/W1587621551","https://openalex.org/W1651834459","https://openalex.org/W2067893691","https://openalex.org/W2077925465","https://openalex.org/W2002401414","https://openalex.org/W1593807356","https://openalex.org/W2042033780","https://openalex.org/W2364687933","https://openalex.org/W2035921327"],"abstract_inverted_index":{"Graft":[0],"vs.":[1],"host":[2,93],"disease":[3],"(GVHD)":[4],"remains":[5],"one":[6],"of":[7,25,42,55,73,86,102,109,124,161,163,169],"the":[8,26,30,40,71,106,120,159,170],"main":[9],"problems":[10],"associated":[11],"with":[12,29,52,76,127,173,183],"bone":[13,57],"marrow":[14,58,125],"transplantation.":[15],"The":[16],"current":[17],"studies":[18],"were":[19,155],"undertaken":[20],"to":[21,132],"determine":[22],"whether":[23],"treatment":[24,85],"donor":[27,121,171],"inoculum":[28,172],"anticytotoxic":[31],"cell":[32,139,187],"compound":[33],"L-leucyl-L-leucine":[34],"methyl":[35],"ester":[36],"(Leu-Leu-OMe)":[37],"would":[38],"alter":[39],"development":[41],"GVHD":[43,177],"in":[44,96,158,178],"a":[45,53],"murine":[46,180],"model.":[47],"Irradiated":[48],"recipient":[49],"mice":[50,110],"transplanted":[51],"mixture":[54],"control":[56,164],"and":[59,116,152],"spleen":[60,103],"cells":[61,74,87,104,115,126],"from":[62,68,89,105],"naive":[63],"semiallogeneic":[64],"donors":[65,90],"died":[66],"rapidly":[67],"GVHD,":[69],"whereas":[70],"recipients":[72,162],"incubated":[75],"250":[77,128],"microM":[78,129],"Leu-Leu-OMe":[79,84,130,174],"all":[80],"survived.":[81],"In":[82],"addition,":[83],"obtained":[88],"immunized":[91],"against":[92],"alloantigens":[94],"resulted":[95],"significantly":[97],"prolonged":[98],"survival.":[99],"Phenotypic":[100],"characterization":[101],"various":[107],"groups":[108],"that":[111],"had":[112],"received":[113],"Leu-Leu-OMe-treated":[114,166],"survived":[117],"consistently":[118],"revealed":[119],"phenotype.":[122],"Treatment":[123,168],"appeared":[131],"have":[133],"no":[134,184],"adverse":[135],"effects":[136],"on":[137],"stem":[138,186],"function.":[140],"Erythropoiesis":[141],"was":[142],"undiminished,":[143],"as":[144],"assayed":[145],"by":[146],"splenic":[147],"5-iodo-2'-deoxyuridine-125I":[148],"uptake.":[149],"Moreover,":[150],"granulocytic":[151],"megakaryocytic":[153],"regeneration":[154],"histologically":[156],"equivalent":[157],"spleens":[160],"or":[165],"cells.":[167],"thus":[175],"prevents":[176],"this":[179],"strain":[181],"combination":[182],"apparent":[185],"toxicity.":[188]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
