{"id":"https://openalex.org/W2139720124","doi":"https://doi.org/10.1016/s0140-6736(09)61528-2","title":"H1N1 pneumonitis treated with intravenous zanamivir","display_name":"H1N1 pneumonitis treated with intravenous zanamivir","publication_year":2009,"publication_date":"2009-09-01","ids":{"openalex":"https://openalex.org/W2139720124","doi":"https://doi.org/10.1016/s0140-6736(09)61528-2","mag":"2139720124","pmid":"https://pubmed.ncbi.nlm.nih.gov/19733390"},"language":"en","primary_location":{"id":"doi:10.1016/s0140-6736(09)61528-2","doi":"https://doi.org/10.1016/s0140-6736(09)61528-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0140-6736(09)61528-2","pdf_url":null,"source":{"id":"https://openalex.org/S49861241","display_name":"The Lancet","issn_l":"0099-5355","issn":["0099-5355","0140-6736","1474-547X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071767868","display_name":"Michael Kidd","orcid":"https://orcid.org/0000-0002-5264-9712","observed_orcids":["https://orcid.org/0000-0002-5264-9712"]},"institutions":[{"id":"https://openalex.org/I1340918713","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"I Michael Kidd","raw_affiliation_strings":["Department of Virology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK. Electronic address: Michael.Kidd@uclh.nhs.uk","Department of Virology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Virology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK. Electronic address: Michael.Kidd@uclh.nhs.uk","institution_ids":["https://openalex.org/I1340918713"]},{"raw_affiliation_string":"Department of Virology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK","institution_ids":["https://openalex.org/I1340918713"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110118217","display_name":"Jim Down","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1340918713","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jim Down","raw_affiliation_strings":["Department of Critical Care, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK","institution_ids":["https://openalex.org/I1340918713"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031723032","display_name":"Eleni Nastouli","orcid":"https://orcid.org/0000-0002-1684-2013","observed_orcids":["https://orcid.org/0000-0002-1684-2013"]},"institutions":[{"id":"https://openalex.org/I1340918713","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Eleni Nastouli","raw_affiliation_strings":["Department of Virology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Virology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK","institution_ids":["https://openalex.org/I1340918713"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023210093","display_name":"Rob I. Shulman","orcid":"https://orcid.org/0000-0001-9650-3718","observed_orcids":["https://orcid.org/0000-0001-9650-3718"]},"institutions":[{"id":"https://openalex.org/I1340918713","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rob Shulman","raw_affiliation_strings":["Department of Critical Care, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK","institution_ids":["https://openalex.org/I1340918713"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110292009","display_name":"Paul R. Grant","orcid":"https://orcid.org/0000-0003-2970-141X","observed_orcids":["https://orcid.org/0000-0003-2970-141X"]},"institutions":[{"id":"https://openalex.org/I1340918713","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul R Grant","raw_affiliation_strings":["Department of Virology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Virology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK","institution_ids":["https://openalex.org/I1340918713"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042850205","display_name":"David C. J. Howell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1340918713","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David CJ Howell","raw_affiliation_strings":["Department of Critical Care, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK","institution_ids":["https://openalex.org/I1340918713"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022102306","display_name":"Mervyn Singer","orcid":"https://orcid.org/0000-0002-1042-6350","observed_orcids":["https://orcid.org/0000-0002-1042-6350"]},"institutions":[{"id":"https://openalex.org/I1340918713","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mervyn Singer","raw_affiliation_strings":["Department of Critical Care, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, UK","institution_ids":["https://openalex.org/I1340918713"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5071767868"],"corresponding_institution_ids":["https://openalex.org/I1340918713"],"apc_list":{"value":7890,"currency":"USD","value_usd":7890},"apc_paid":null,"fwci":14.334,"has_fulltext":false,"cited_by_count":92,"citation_normalized_percentile":{"value":0.99265051,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"374","issue":"9694","first_page":"1036","last_page":"1036"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pandemic-h1n1-2009-influenza","display_name":"pandemic H1N1 2009 influenza","score":0.875},{"id":"https://openalex.org/keywords/zanamivir","display_name":"zanamivir","score":0.949999988079071},{"id":"https://openalex.org/keywords/intravenous-antiviral-therapy","display_name":"intravenous antiviral therapy","score":0.8130000233650208},{"id":"https://openalex.org/keywords/oseltamivir-resistance","display_name":"oseltamivir resistance","score":0.8930000066757202},{"id":"https://openalex.org/keywords/neutropenia","display_name":"neutropenia","score":0.8320000171661377},{"id":"https://openalex.org/keywords/hodgkin-lymphoma","display_name":"Hodgkin's disease","score":0.8960000276565552},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.5139999985694885},{"id":"https://openalex.org/keywords/invasive-mechanical-ventilation","display_name":"invasive mechanical ventilation","score":0.8090000152587891},{"id":"https://openalex.org/keywords/critical-care","display_name":"intensive care","score":0.6809999942779541}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8780114650726318},{"id":"https://openalex.org/C2780374985","wikidata":"https://www.wikidata.org/wiki/Q211509","display_name":"Oseltamivir","level":5,"score":0.7301439046859741},{"id":"https://openalex.org/C2777961210","wikidata":"https://www.wikidata.org/wiki/Q927148","display_name":"Bronchoalveolar lavage","level":3,"score":0.7081074714660645},{"id":"https://openalex.org/C2777063308","wikidata":"https://www.wikidata.org/wiki/Q1435822","display_name":"Neutropenia","level":3,"score":0.6856294870376587},{"id":"https://openalex.org/C2781442963","wikidata":"https://www.wikidata.org/wiki/Q146075","display_name":"Zanamivir","level":5,"score":0.5823562741279602},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.5406668782234192},{"id":"https://openalex.org/C2776703206","wikidata":"https://www.wikidata.org/wiki/Q2731762","display_name":"Teicoplanin","level":5,"score":0.5182861685752869},{"id":"https://openalex.org/C2779375183","wikidata":"https://www.wikidata.org/wiki/Q421670","display_name":"Meropenem","level":4,"score":0.48827099800109863},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4716101288795471},{"id":"https://openalex.org/C2776779939","wikidata":"https://www.wikidata.org/wiki/Q1479485","display_name":"Hypoxemia","level":2,"score":0.4636600613594055},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.44510340690612793},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.40724432468414307},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.33541184663772583},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.305306613445282},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.28197523951530457},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.2637636661529541},{"id":"https://openalex.org/C2778980435","wikidata":"https://www.wikidata.org/wiki/Q424027","display_name":"Vancomycin","level":4,"score":0.221551775932312},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.18497762084007263},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.14342311024665833},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.1427399218082428},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.10239756107330322},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.0},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000280","descriptor_name":"Administration, Inhalation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001992","descriptor_name":"Bronchoalveolar Lavage Fluid","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D003422","descriptor_name":"Critical Care","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006689","descriptor_name":"Hodgkin Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007262","descriptor_name":"Infusions, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008775","descriptor_name":"Methylprednisolone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D009503","descriptor_name":"Neutropenia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D009503","descriptor_name":"Neutropenia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D011024","descriptor_name":"Pneumonia, Viral","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011024","descriptor_name":"Pneumonia, Viral","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011024","descriptor_name":"Pneumonia, Viral","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011024","descriptor_name":"Pneumonia, Viral","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D016867","descriptor_name":"Immunocompromised Host","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053118","descriptor_name":"Influenza A Virus, H1N1 Subtype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053243","descriptor_name":"Zanamivir","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0140-6736(09)61528-2","doi":"https://doi.org/10.1016/s0140-6736(09)61528-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0140-6736(09)61528-2","pdf_url":null,"source":{"id":"https://openalex.org/S49861241","display_name":"The Lancet","issn_l":"0099-5355","issn":["0099-5355","0140-6736","1474-547X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet","raw_type":"journal-article"},{"id":"pmid:19733390","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19733390","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lancet (London, England)","raw_type":"Case Reports"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:88745","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/88745/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"LANCET , 374 (9694) p. 1036. (2009)","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W1923705646","https://openalex.org/W2144716012"],"related_works":["https://openalex.org/W2065412019","https://openalex.org/W2052682577","https://openalex.org/W2411406557","https://openalex.org/W1981737639","https://openalex.org/W1977401490","https://openalex.org/W1991619792","https://openalex.org/W2127732428","https://openalex.org/W1971212145","https://openalex.org/W2981159615","https://openalex.org/W1990004333"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}