{"id":"https://openalex.org/W2139689892","doi":"https://doi.org/10.1083/jcb.130.5.1105","title":"Hierarchy of mechanisms involved in generating Na/K-ATPase polarity in MDCK epithelial cells.","display_name":"Hierarchy of mechanisms involved in generating Na/K-ATPase polarity in MDCK epithelial cells.","publication_year":1995,"publication_date":"1995-09-01","ids":{"openalex":"https://openalex.org/W2139689892","doi":"https://doi.org/10.1083/jcb.130.5.1105","mag":"2139689892","pmid":"https://pubmed.ncbi.nlm.nih.gov/7657695","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2120560"},"language":"en","primary_location":{"id":"doi:10.1083/jcb.130.5.1105","doi":"https://doi.org/10.1083/jcb.130.5.1105","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.130.5.1105","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2139689892"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2120560/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042998715","display_name":"Robert W. Mays","orcid":"https://orcid.org/0000-0002-9682-2222","observed_orcids":["https://orcid.org/0000-0002-9682-2222"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R W Mays","raw_affiliation_strings":["Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035169822","display_name":"Kathleen A. Siemers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K A Siemers","raw_affiliation_strings":["Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051299613","display_name":"B A Fritz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B A Fritz","raw_affiliation_strings":["Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103683086","display_name":"Anson W. Lowe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A W Lowe","raw_affiliation_strings":["Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030256996","display_name":"Gerrit van MEER","orcid":"https://orcid.org/0000-0002-5976-6436","observed_orcids":["https://orcid.org/0000-0002-5976-6436"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G van Meer","raw_affiliation_strings":["Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077624417","display_name":"William James Nelson","orcid":"https://orcid.org/0000-0003-3039-3776","observed_orcids":["https://orcid.org/0000-0003-3039-3776"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W J Nelson","raw_affiliation_strings":["Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Physiology, Stanford University School of Medicine, California 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.7625,"has_fulltext":true,"cited_by_count":213,"citation_normalized_percentile":{"value":0.97181671,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"130","issue":"5","first_page":"1105","last_page":"1115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.7207000255584717,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.7207000255584717,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.19670000672340393,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.018699999898672104,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/na-k-atpase","display_name":"Na+/K+-ATPase","score":0.9419999718666077},{"id":"https://openalex.org/keywords/mdck-ii-cells","display_name":"MDCK II cells","score":0.7649999856948853},{"id":"https://openalex.org/keywords/golgi-apparatus","display_name":"Golgi apparatus","score":0.7149999737739563},{"id":"https://openalex.org/keywords/protein-sorting","display_name":"protein sorting","score":0.7739999890327454},{"id":"https://openalex.org/keywords/basolateral-membrane","display_name":"basolateral membrane","score":0.9240000247955322},{"id":"https://openalex.org/keywords/apical-membrane","display_name":"apical membrane","score":0.8949999809265137},{"id":"https://openalex.org/keywords/e-cadherin","display_name":"E-cadherin","score":0.972000002861023},{"id":"https://openalex.org/keywords/glucosylceramide","display_name":"glucosylceramide","score":0.9810000061988831},{"id":"https://openalex.org/keywords/sphingolipid-biosynthesis","display_name":"sphingolipid biosynthesis","score":0.8740000128746033},{"id":"https://openalex.org/keywords/fumonisin-b1","display_name":"fumonisin B1","score":0.9789999723434448},{"id":"https://openalex.org/keywords/ceramide","display_name":"ceramide","score":0.9779999852180481},{"id":"https://openalex.org/keywords/membrane-trafficking","display_name":"membrane trafficking","score":0.5070000290870667}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8115360140800476},{"id":"https://openalex.org/C49353375","wikidata":"https://www.wikidata.org/wiki/Q189100","display_name":"Cell polarity","level":3,"score":0.59888756275177},{"id":"https://openalex.org/C81089528","wikidata":"https://www.wikidata.org/wiki/Q5134986","display_name":"clone (Java method)","level":3,"score":0.5911067724227905},{"id":"https://openalex.org/C3018436504","wikidata":"https://www.wikidata.org/wiki/Q29548","display_name":"Apical membrane","level":3,"score":0.5495582222938538},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5104283690452576},{"id":"https://openalex.org/C176080148","wikidata":"https://www.wikidata.org/wiki/Q207604","display_name":"Apical cell","level":3,"score":0.4968452751636505},{"id":"https://openalex.org/C119062480","wikidata":"https://www.wikidata.org/wiki/Q83181","display_name":"Golgi apparatus","level":3,"score":0.486553817987442},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.43169671297073364},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.4288485646247864},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.4271673262119293},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.356570303440094},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.25438088178634644},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.20647543668746948},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.07981029152870178}],"mesh":[{"descriptor_ui":"D000254","descriptor_name":"Sodium-Potassium-Exchanging ATPase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006028","descriptor_name":"Glycosphingolipids","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D006028","descriptor_name":"Glycosphingolipids","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D006028","descriptor_name":"Glycosphingolipids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006056","descriptor_name":"Golgi Apparatus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009183","descriptor_name":"Mycotoxins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013723","descriptor_name":"Teratogens","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015820","descriptor_name":"Cadherins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016764","descriptor_name":"Cell Polarity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017261","descriptor_name":"Glycosylphosphatidylinositols","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D037341","descriptor_name":"Fumonisins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1083/jcb.130.5.1105","doi":"https://doi.org/10.1083/jcb.130.5.1105","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.130.5.1105","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2120560","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2120560/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2120560/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},{"id":"pmid:7657695","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7657695","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.274.3722","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.274.3722","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/0d/9d/J_Cell_Biol_1995_Sep_1_130(5)_1105-1115.tar.gz","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.329.800","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.329.800","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jcb.rupress.org/content/130/5/1105.full.pdf","raw_type":"text"},{"id":"pmh:oai:dspace.library.uu.nl:1874/293026","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/293026","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:uu:oai:dspace.library.uu.nl:1874/293026","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/293026","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Cell Biology, 130(5), 1105. Rockefeller University Press","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2120560","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2120560/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2120560/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306182","display_name":"March of Dimes Foundation","ror":"https://ror.org/04bd5p711"},{"id":"https://openalex.org/F4320322224","display_name":"Nella and Leon Benoziyo Center for Neurological Diseases, Weizmann Institute of Science","ror":"https://ror.org/0316ej306"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139689892.pdf","grobid_xml":"https://content.openalex.org/works/W2139689892.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W1487026876","https://openalex.org/W1535433473","https://openalex.org/W1566441785","https://openalex.org/W1584661703","https://openalex.org/W1718606833","https://openalex.org/W1963556374","https://openalex.org/W1965857079","https://openalex.org/W1976094538","https://openalex.org/W1979997703","https://openalex.org/W1982584353","https://openalex.org/W1988087210","https://openalex.org/W2002299808","https://openalex.org/W2013454744","https://openalex.org/W2028663640","https://openalex.org/W2033721503","https://openalex.org/W2035946849","https://openalex.org/W2043625609","https://openalex.org/W2046047219","https://openalex.org/W2063301738","https://openalex.org/W2064754325","https://openalex.org/W2070947895","https://openalex.org/W2071115686","https://openalex.org/W2072384875","https://openalex.org/W2076816515","https://openalex.org/W2079241673","https://openalex.org/W2079420925","https://openalex.org/W2082861222","https://openalex.org/W2084617331","https://openalex.org/W2086986392","https://openalex.org/W2089138822","https://openalex.org/W2089200610","https://openalex.org/W2098694680","https://openalex.org/W2106370142","https://openalex.org/W2106508078","https://openalex.org/W2111930154","https://openalex.org/W2115903414","https://openalex.org/W2118739947","https://openalex.org/W2120138917","https://openalex.org/W2120222594","https://openalex.org/W2128474008","https://openalex.org/W2132452783","https://openalex.org/W2133388060","https://openalex.org/W2133449590","https://openalex.org/W2136955592","https://openalex.org/W2139357515","https://openalex.org/W2141428099","https://openalex.org/W2147434547","https://openalex.org/W2160696263","https://openalex.org/W2164057833","https://openalex.org/W2170385301","https://openalex.org/W2179009703","https://openalex.org/W2186768487","https://openalex.org/W2325846132","https://openalex.org/W2409258959","https://openalex.org/W2470956167","https://openalex.org/W3210318534"],"related_works":["https://openalex.org/W2396132509","https://openalex.org/W2002299808","https://openalex.org/W1988087210","https://openalex.org/W2221044769","https://openalex.org/W1552591396","https://openalex.org/W2170477767","https://openalex.org/W1966704700","https://openalex.org/W1547484539","https://openalex.org/W2316483922"],"abstract_inverted_index":{"We":[0],"have":[1],"studied":[2],"mechanisms":[3,267],"involved":[4],"in":[5,12,76,81,89,103,120,141,146,181,268,279],"generating":[6],"a":[7,112,130,263],"polarized":[8,26],"distribution":[9],"of":[10,16,19,28,31,58,67,84,172,195,219,225,229,255,260,265,283],"Na/K-ATPase":[11,72,199,240,261,277],"the":[13,32,49,64,68,77,82,100,138,186,193,222,234,243,253,269,280],"basal-lateral":[14,35,56,65,78,93,101,117,160,206,223,246,308],"membrane":[15,66,79,94,102,118,140,224,309],"two":[17],"clones":[18,24],"MDCK":[20,105,284],"II":[21],"cells.":[22,123,227],"Both":[23],"exhibit":[25],"distributions":[27],"marker":[29],"proteins":[30,119],"apical":[33,54,139,158,204,244,293,306],"and":[34,55,62,129,151,159,175,198,205,239,245,272,275,307],"membranes,":[36,161,207,247],"including":[37],"Na/K-ATPase,":[38,44,176],"at":[39],"steady":[40],"state.":[41],"Newly":[42],"synthesized":[43],"however,":[45],"is":[46,73,97,110],"delivered":[47,154,201],"from":[48,291],"Golgi":[50,270,281],"complex":[51,271,282],"to":[52,63,99,137,156,163,202,209,221,232,242],"both":[53,90,104,157,203],"membranes":[57],"one":[59],"clone":[60,70,121,142,147,182,210],"(II/J),":[61],"other":[69,305],"(II/G);":[71],"selectively":[74],"retained":[75],"resulting":[80],"generation":[83,254],"complete":[85,256],"cell":[86,257],"surface":[87,258],"polarity":[88,259],"clones.":[91],"Another":[92],"protein,":[95],"E-cadherin,":[96],"sorted":[98],"clones,":[106],"demonstrating":[107],"that":[108,252,276],"there":[109],"not":[111],"general":[113],"sorting":[114,171,218,241,266,278,302],"defect":[115],"for":[116,304],"II/J":[122,148,211],"A":[124],"glycosyl-phosphatidylinositol":[125],"(GPI)-anchored":[126],"protein":[127],"(GP-2)":[128],"glycosphingolipid":[131],"(glucosylceramide,":[132],"GlcCer)":[133],"are":[134,153,200],"preferentially":[135],"transported":[136],"II/G":[143,183,226],"cells,":[144,149],"but,":[145],"GP-2":[150,174,197,238],"GlcCer":[152],"equally":[155],"similar":[162,208],"Na/K-ATPase.":[164],"To":[165],"examine":[166],"this":[167],"apparent":[168],"inter-relationship":[169],"between":[170],"GlcCer,":[173],"sphingolipid":[177],"synthesis":[178],"was":[179],"inhibited":[180],"cells":[184,285],"with":[185],"fungal":[187],"metabolite,":[188],"Fumonisin":[189],"B1":[190],"(FB1).":[191],"In":[192],"presence":[194],"FB1,":[196],"cells;":[212],"FB1":[213,235],"had":[214],"no":[215],"effect":[216],"on":[217],"E-cadherin":[220],"Addition":[228],"exogenous":[230],"ceramide,":[231],"circumvent":[233],"block,":[236],"restored":[237],"respectively.":[248],"These":[249,295],"results":[250,296],"show":[251],"involves":[262],"hierarchy":[264],"plasma":[273],"membrane,":[274],"may":[286],"be":[287],"regulated":[288],"by":[289],"exclusion":[290],"an":[292],"pathway(s).":[294],"also":[297],"provide":[298],"new":[299],"insights":[300],"into":[301],"pathways":[303],"proteins.":[310]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}