{"id":"https://openalex.org/W2139608940","doi":"https://doi.org/10.4172/2329-9509.1000113","title":"Bone Mineral Density in Bulgarian Patients with Type 1 Diabetes Mellitus","display_name":"Bone Mineral Density in Bulgarian Patients with Type 1 Diabetes Mellitus","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2139608940","doi":"https://doi.org/10.4172/2329-9509.1000113","mag":"2139608940"},"language":"en","primary_location":{"id":"doi:10.4172/2329-9509.1000113","doi":"https://doi.org/10.4172/2329-9509.1000113","is_oa":false,"landing_page_url":"https://doi.org/10.4172/2329-9509.1000113","pdf_url":null,"source":{"id":"https://openalex.org/S2764729060","display_name":"Journal of Osteoporosis and Physical Activity","issn_l":"2329-9509","issn":["2329-9509"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Osteoporosis and Physical Activity","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046710630","display_name":"Marianna P. Yaneva","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Marianna Yaneva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5046710630"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7246,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.83628066,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"02","issue":"01","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9729999899864197},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.996999979019165},{"id":"https://openalex.org/keywords/osteocalcin","display_name":"osteocalcin","score":0.7089999914169312},{"id":"https://openalex.org/keywords/deoxypyridinoline","display_name":"deoxypyridinoline","score":0.972000002861023},{"id":"https://openalex.org/keywords/bone-turnover-markers","display_name":"bone turnover markers","score":0.972000002861023},{"id":"https://openalex.org/keywords/bone-resorption","display_name":"bone resorption","score":0.906000018119812},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.9139999747276306},{"id":"https://openalex.org/keywords/lumbar-spine","display_name":"lumbar spine","score":0.8240000009536743},{"id":"https://openalex.org/keywords/femoral-neck","display_name":"femoral neck","score":0.9990000128746033},{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":0.5989999771118164},{"id":"https://openalex.org/keywords/bulgarian-patients","display_name":"Bulgarian patients","score":0.7269999980926514},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7480000257492065},{"id":"https://openalex.org/keywords/age-differences","display_name":"age differences","score":0.5170000195503235},{"id":"https://openalex.org/keywords/ethnic-differences","display_name":"ethnic differences","score":0.6650000214576721},{"id":"https://openalex.org/keywords/z-score","display_name":"Z-score","score":0.4909999966621399},{"id":"https://openalex.org/keywords/dual-energy-x-ray-absorptiometry","display_name":"dual-energy X-ray absorptiometry","score":0.7730000019073486}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9249898195266724},{"id":"https://openalex.org/C2780343019","wikidata":"https://www.wikidata.org/wiki/Q7918","display_name":"Bulgarian","level":2,"score":0.7678750157356262},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.6187718510627747},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5993797779083252},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.544823169708252},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.42531082034111023},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3928587734699249},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35730862617492676},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.26929259300231934},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.1832546591758728},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4172/2329-9509.1000113","doi":"https://doi.org/10.4172/2329-9509.1000113","is_oa":false,"landing_page_url":"https://doi.org/10.4172/2329-9509.1000113","pdf_url":null,"source":{"id":"https://openalex.org/S2764729060","display_name":"Journal of Osteoporosis and Physical Activity","issn_l":"2329-9509","issn":["2329-9509"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320466","host_organization_name":"OMICS Publishing Group","host_organization_lineage":["https://openalex.org/P4310320466"],"host_organization_lineage_names":["OMICS Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Osteoporosis and Physical Activity","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W633883572","https://openalex.org/W1494806282","https://openalex.org/W1779434077","https://openalex.org/W1964450577","https://openalex.org/W1969559625","https://openalex.org/W1971333176","https://openalex.org/W1973255479","https://openalex.org/W1978759916","https://openalex.org/W1982272373","https://openalex.org/W2002036528","https://openalex.org/W2018189647","https://openalex.org/W2020267609","https://openalex.org/W2036431532","https://openalex.org/W2037415919","https://openalex.org/W2042699736","https://openalex.org/W2057631007","https://openalex.org/W2068732522","https://openalex.org/W2072414506","https://openalex.org/W2072794211","https://openalex.org/W2095638549","https://openalex.org/W2102939161","https://openalex.org/W2108088189","https://openalex.org/W2116288435","https://openalex.org/W2129451833","https://openalex.org/W2132556078","https://openalex.org/W2145207751","https://openalex.org/W2154123318","https://openalex.org/W2159897314","https://openalex.org/W2165110758","https://openalex.org/W2409385610","https://openalex.org/W2520432709"],"related_works":["https://openalex.org/W2117984321","https://openalex.org/W2319165719","https://openalex.org/W2987631564","https://openalex.org/W2348042825","https://openalex.org/W2072520758","https://openalex.org/W4323858156","https://openalex.org/W2083871100","https://openalex.org/W2006919588","https://openalex.org/W2789454211","https://openalex.org/W83157159"],"abstract_inverted_index":{"Aim":[0],"of":[1,41,87,103,108,213,227,315,345,365,382,390,411],"the":[2,6,316,328,351,363,366,374,380,383,409,419],"study:":[3],"To":[4],"examine":[5],"bone":[7,34,42,48,214,228,317,322,330,353,367,422],"mineral":[8,331,368],"density":[9],"(BMD)":[10],"in":[11,20,114,191,194,198,216,234,237,268,288,302,309,333],"Bulgarian":[12],"patients":[13,54,236,303],"with":[14,33,55,196,239,250,261,275,304,373,403],"type":[15,56,115,305,391],"1":[16,57,116,306,392],"diabetes":[17,346,393],"mellitus":[18,394],"(DM)":[19],"comparison":[21,195,238],"to":[22,340,385,401],"age-":[23,75],"sex-":[24],"and":[25,30,44,51,61,68,72,76,85,90,105,142,158,176,241,257,282,296,355],"ethnically":[26],"matched":[27,78,243,312],"healthy":[28,79],"controls":[29,80],"its":[31],"correlation":[32,249,260],"turnover":[35,318],"markers:":[36],"oteocalcin":[37],"as":[38,47,210,224,324],"a":[39,211,225,325,387],"marker":[40,212,226],"formation":[43,215],"deoxypyridinoline":[45,109],"cross-laps":[46,110],"resorption":[49,229,323],"marker.\r\nMaterials":[50],"methods:":[52],"162":[53],"DM":[58,117,133,149,167,182,307],"(97":[59],"females":[60],"65":[62],"males)":[63],"age":[64,240],"29.17":[65],"yrs.":[66],"(20-40)":[67],"200":[69],"(100":[70],"women":[71,144,177],"100":[73],"men)":[74],"sex":[77,242,311],"were":[81,111,230],"analyzed":[82],"for":[83,123,207,327],"BMD":[84,113,251,276,291,384],"Z-score":[86],"lumbar":[88,124,253,278,294],"spine":[89,125,254,279,295],"femoral":[91,159,264,284,297],"neck":[92,160,265,285,298],"by":[93],"dual":[94],"X-ray":[95],"absorptiometry":[96],"(DXA)":[97],"using":[98],"Lunar":[99],"DPX-A.":[100],"Plasma":[101],"levels":[102,107,122,209,223],"osteocalcin":[104,208],"urine":[106],"determined.\r\nResults:":[112],"showed":[118,246,272],"statistically":[119,204],"significant":[120,205,247],"lower":[121,301],"L1-L4-":[126],"men":[127,162],"(1.2114":[128],"g/":[129,136,152,170,185],"cm2":[130,137,153,171,186],"\u00b1":[131,138,147,154,165,172,180,187],"0,1587":[132],"vs.":[134],"1.3346":[135],"0,1635":[139],"controls,":[140,156,174,189],"P<0.05)":[141,157,175,190],"L1-L4":[143],"(1.1035":[145],"g/cm2":[146,164,179],"0.1269":[148],"vs":[150,168,183],"1.1978":[151],"0,1269":[155],"-":[161],"(0.9138":[163],"2134":[166],"0.9868":[169],"0.1534":[173],"(0.8656":[178],"0.1223":[181],"0.9236":[184],"0.145":[188],"both":[192,217],"sexes":[193],"that":[197,262],"control":[199,344,360],"group.":[200],"We":[201],"found":[202],"no":[203],"difference":[206],"groups":[218],"(P=0.062),":[219],"while":[220],"deohypyridinoline":[221],"(DPD)":[222],"significantly":[231,300],"higher":[232],"(P<0.01)":[233],"diabetic":[235,269,289,334,375],"controls.":[244,313],"Osteocalcin":[245],"negative":[248,259],"at":[252,263,277,283,293,418],"(r=-0.418;":[255],"P=0.004)":[256],"nonsignificant":[258,273],"(r=-0.271;":[266],"P=0.078)":[267],"patients.":[270,335],"DPD":[271],"correlations":[274],"(r=-0.024;":[280],"P=0.846)":[281],"(r=0.143;":[286],"P=0.259)":[287],"patients.\r\nConclusions:":[290],"measured":[292],"was":[299],"than":[308,395],"age-and":[310],"Levels":[314],"markers":[319],"indicate":[320],"increased":[321],"reason":[326],"decreased":[329],"content":[332,369],"Prospective":[336],"studies":[337],"are":[338],"needed":[339],"determine":[341],"whether":[342,356],"metabolic":[343,359],"has":[347],"any":[348],"influence":[349],"upon":[350,408],"observed":[352],"changes":[354],"keeping":[357],"good":[358],"can":[361],"minimize":[362],"reduction":[364,381],"like":[370,406],"it":[371],"happens":[372],"microangioapthy.":[376],"If":[377],"we":[378,396],"consider":[379],"be":[386],"specific":[388],"complication":[389],"should":[397],"take":[398],"appropriate":[399,412],"measures":[400],"cope":[402],"this":[404],"problem":[405],"stressing":[407],"importance":[410],"diet":[413],"adequate":[414],"physical":[415],"activity":[416],"especially":[417],"time":[420],"peak":[421],"mass":[423],"is":[424],"being":[425],"accumulated.":[426]},"counts_by_year":[{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":3}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}