{"id":"https://openalex.org/W2139590802","doi":null,"title":"Neuropathological changes in brain cortex and hippocampus in a rat model of Alzheimer's disease.","display_name":"Neuropathological changes in brain cortex and hippocampus in a rat model of Alzheimer's disease.","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2139590802","mag":"2139590802","pmid":"https://pubmed.ncbi.nlm.nih.gov/21725500","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3639737"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:2656920","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3639737","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3639737","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074951513","display_name":"Maliheh Nobakht","orcid":"https://orcid.org/0000-0002-4281-5924","observed_orcids":["https://orcid.org/0000-0002-4281-5924","https://orcid.org/0000-0003-2352-6331"]},"institutions":[{"id":"https://openalex.org/I110525433","display_name":"Islamic Azad University, Tehran","ror":"https://ror.org/01kzn7k21","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433"]},{"id":"https://openalex.org/I155419210","display_name":"Islamic Azad University, Science and Research Branch","ror":"https://ror.org/03187yj51","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I155419210"]},{"id":"https://openalex.org/I161106909","display_name":"Iran University of Medical Sciences","ror":"https://ror.org/03w04rv71","country_code":"IR","type":"education","lineage":["https://openalex.org/I161106909"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Maliheh Nobakht","raw_affiliation_strings":["Dept. of Pathology, Science and Research Branch Islamic Azad University, Tehran, Iran","Dept. of  Histology and Neuroscience, School of Medicine, Iran University of Medical Sciences, Tehram, Iran","Anti-Microbial Resistance Research Center, Iran University of Medical Sciences, Tehran, Iran; 4Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran","Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pathology, Science and Research Branch Islamic Azad University, Tehran, Iran","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I155419210"]},{"raw_affiliation_string":"Dept. of  Histology and Neuroscience, School of Medicine, Iran University of Medical Sciences, Tehram, Iran","institution_ids":["https://openalex.org/I161106909"]},{"raw_affiliation_string":"Anti-Microbial Resistance Research Center, Iran University of Medical Sciences, Tehran, Iran; 4Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I161106909"]},{"raw_affiliation_string":"Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I161106909","https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107887158","display_name":"Seyed Mohammad Hoseini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I110525433","display_name":"Islamic Azad University, Tehran","ror":"https://ror.org/01kzn7k21","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433"]},{"id":"https://openalex.org/I155419210","display_name":"Islamic Azad University, Science and Research Branch","ror":"https://ror.org/03187yj51","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I155419210"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Seyed Mohammad Hoseini","raw_affiliation_strings":["Dept. of Pathology, Science and Research Branch Islamic Azad University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pathology, Science and Research Branch Islamic Azad University, Tehran, Iran","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I155419210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022938595","display_name":"Pejman Mortazavi","orcid":"https://orcid.org/0000-0002-2795-5371","observed_orcids":["https://orcid.org/0000-0002-2795-5371"]},"institutions":[{"id":"https://openalex.org/I110525433","display_name":"Islamic Azad University, Tehran","ror":"https://ror.org/01kzn7k21","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433"]},{"id":"https://openalex.org/I155419210","display_name":"Islamic Azad University, Science and Research Branch","ror":"https://ror.org/03187yj51","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I155419210"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Pejman Mortazavi","raw_affiliation_strings":["Dept. of Pathology, Science and Research Branch Islamic Azad University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pathology, Science and Research Branch Islamic Azad University, Tehran, Iran","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I155419210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069066244","display_name":"Iraj Sohrabi Haghdoost","orcid":"https://orcid.org/0000-0003-3136-5988","observed_orcids":["https://orcid.org/0000-0003-3136-5988"]},"institutions":[{"id":"https://openalex.org/I110525433","display_name":"Islamic Azad University, Tehran","ror":"https://ror.org/01kzn7k21","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433"]},{"id":"https://openalex.org/I155419210","display_name":"Islamic Azad University, Science and Research Branch","ror":"https://ror.org/03187yj51","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I155419210"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Iraj Sohrabi","raw_affiliation_strings":["Dept. of Pathology, Science and Research Branch Islamic Azad University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pathology, Science and Research Branch Islamic Azad University, Tehran, Iran","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I155419210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112036485","display_name":"Banafshe Esmaeilzade","orcid":"https://orcid.org/0000-0002-6204-4063","observed_orcids":["https://orcid.org/0000-0002-6204-4063","https://orcid.org/0000-0002-4752-6128"]},"institutions":[{"id":"https://openalex.org/I161106909","display_name":"Iran University of Medical Sciences","ror":"https://ror.org/03w04rv71","country_code":"IR","type":"education","lineage":["https://openalex.org/I161106909"]},{"id":"https://openalex.org/I52623189","display_name":"Bushehr University of Medical Sciences","ror":"https://ror.org/02y18ts25","country_code":"IR","type":"education","lineage":["https://openalex.org/I52623189"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Banafshe Esmailzade","raw_affiliation_strings":["Dept. of Anatomy, School of Medicine, Iran University of Medical Sciences, Tehran, Iran","Dept. of Anatomy, School of Medicine, Bushehr University of Medical Science, Bushehr, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Anatomy, School of Medicine, Iran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I161106909"]},{"raw_affiliation_string":"Dept. of Anatomy, School of Medicine, Bushehr University of Medical Science, Bushehr, Iran","institution_ids":["https://openalex.org/I52623189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109260017","display_name":"Nahid Rahbar\u2010Roshandel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I110525433","display_name":"Islamic Azad University, Tehran","ror":"https://ror.org/01kzn7k21","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433"]},{"id":"https://openalex.org/I155419210","display_name":"Islamic Azad University, Science and Research Branch","ror":"https://ror.org/03187yj51","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I155419210"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Nahid Rahbar Rooshandel","raw_affiliation_strings":["Dept. of Pathology, Science and Research Branch Islamic Azad University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pathology, Science and Research Branch Islamic Azad University, Tehran, Iran","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I155419210"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084475238","display_name":"Shila Omidzahir","orcid":"https://orcid.org/0000-0002-0019-6491","observed_orcids":["https://orcid.org/0000-0002-0019-6491"]},"institutions":[{"id":"https://openalex.org/I23946033","display_name":"University of Tehran","ror":"https://ror.org/05vf56z40","country_code":"IR","type":"education","lineage":["https://openalex.org/I23946033"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Shila Omidzahir","raw_affiliation_strings":["Veterinary Medicine, Faculty of Specialized Veterinary Science, Tehran University of Veterinary Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Medicine, Faculty of Specialized Veterinary Science, Tehran University of Veterinary Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I23946033"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0565,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.71315142,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"15","issue":"1-2","first_page":"51","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9959999918937683},{"id":"https://openalex.org/keywords/rat-model","display_name":"rat model","score":0.7329999804496765},{"id":"https://openalex.org/keywords/amyloid-beta-40","display_name":"A\u03b240","score":0.8180000185966492},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.9700000286102295},{"id":"https://openalex.org/keywords/cerebral-cortex","display_name":"cerebral cortex","score":0.9890000224113464},{"id":"https://openalex.org/keywords/amyloid-deposition","display_name":"amyloid deposition","score":0.722000002861023},{"id":"https://openalex.org/keywords/memory-impairment","display_name":"memory impairment","score":0.7789999842643738},{"id":"https://openalex.org/keywords/passive-avoidance","display_name":"passive avoidance","score":0.8080000281333923},{"id":"https://openalex.org/keywords/spatial-alternation","display_name":"spatial alternation","score":0.8519999980926514},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.7110000252723694},{"id":"https://openalex.org/keywords/congo-red-staining","display_name":"Congo red staining","score":0.6850000023841858}],"concepts":[{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.8661475777626038},{"id":"https://openalex.org/C37753355","wikidata":"https://www.wikidata.org/wiki/Q911877","display_name":"Nissl body","level":3,"score":0.7209780216217041},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.5830969214439392},{"id":"https://openalex.org/C2777348757","wikidata":"https://www.wikidata.org/wiki/Q2346577","display_name":"Cortex (anatomy)","level":2,"score":0.561169445514679},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.5348554849624634},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.473205029964447},{"id":"https://openalex.org/C2780715579","wikidata":"https://www.wikidata.org/wiki/Q2603645","display_name":"Entorhinal cortex","level":3,"score":0.47003549337387085},{"id":"https://openalex.org/C2781041448","wikidata":"https://www.wikidata.org/wiki/Q75839","display_name":"Cerebral cortex","level":2,"score":0.46559226512908936},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.4480460584163666},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.43322518467903137},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3584028482437134},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.35836514830589294},{"id":"https://openalex.org/C74864618","wikidata":"https://www.wikidata.org/wiki/Q2332446","display_name":"Staining","level":2,"score":0.18189531564712524},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.09437578916549683},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001362","descriptor_name":"Avoidance Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003224","descriptor_name":"Congo Red","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013194","descriptor_name":"Staining and Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016923","descriptor_name":"Cell Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020287","descriptor_name":"In Situ Nick-End Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:2656920","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3639737","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3639737","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3639737","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iran Biomed J","raw_type":"Text"},{"id":"pmid:21725500","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21725500","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iranian biomedical journal","raw_type":"Journal Article"},{"id":"mag:2139590802","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21725500","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2656920","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3639737","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1501293323","https://openalex.org/W1572865480","https://openalex.org/W1594259295","https://openalex.org/W1743329534","https://openalex.org/W1915192275","https://openalex.org/W1966192630","https://openalex.org/W1966484579","https://openalex.org/W1966711088","https://openalex.org/W1973541476","https://openalex.org/W1982064952","https://openalex.org/W1993158184","https://openalex.org/W1999514420","https://openalex.org/W2004266498","https://openalex.org/W2008254819","https://openalex.org/W2013356100","https://openalex.org/W2016777985","https://openalex.org/W2027189256","https://openalex.org/W2030389529","https://openalex.org/W2035235911","https://openalex.org/W2036288989","https://openalex.org/W2038937191","https://openalex.org/W2057013121","https://openalex.org/W2075176032","https://openalex.org/W2103279359","https://openalex.org/W2110765139","https://openalex.org/W2119682731","https://openalex.org/W2126974689","https://openalex.org/W2136825556","https://openalex.org/W2138302361","https://openalex.org/W2158748165","https://openalex.org/W2161178395","https://openalex.org/W2182211804","https://openalex.org/W2410226793"],"related_works":["https://openalex.org/W2297758400","https://openalex.org/W2366866421","https://openalex.org/W2363036875","https://openalex.org/W4409858378","https://openalex.org/W2095044315","https://openalex.org/W2375483331","https://openalex.org/W2581595689","https://openalex.org/W2319158965","https://openalex.org/W2361272105","https://openalex.org/W2400093217"],"abstract_inverted_index":{"BACKGROUND:":[0],"Alzheimer's":[1],"disease":[2],"(AD)":[3],"is":[4],"a":[5,33,184],"neurodegenerative":[6],"disorder":[7],"with":[8],"progressive":[9],"loss":[10,154],"of":[11,19,36,104,107,132,155,188,228],"cognitive":[12],"abilities":[13],"and":[14,29,51,64,73,81,91,129,146,160,163,169,191,201,215,226],"memory":[15,176],"loss.":[16],"The":[17,54,98],"aim":[18],"this":[20],"study":[21],"was":[22,100,235],"to":[23,59,199],"compare":[24],"neuropathological":[25],"changes":[26],"in":[27,32,135,143,149,157,178,195,210,224,237],"hippocampus":[28,123,145,159,214,227],"brain":[30],"cortex":[31,162,225],"rat":[34],"model":[35],"AD.":[37],"METHODS:":[38],"Adult":[39],"male":[40],"Albino":[41],"Wistar":[42],"rats":[43,55],"(weighing":[44],"250-300":[45],"g)":[46],"were":[47,56,76,96,208,222],"used":[48],"for":[49],"behavioral":[50,70,127],"histopathological":[52],"studies.":[53],"randomly":[57],"assigned":[58],"three":[60],"groups:":[61],"control,":[62],"sham":[63,202],"Beta":[65],"amyloid":[66,206,220],"(ABeta)":[67],"injection.":[68],"For":[69,85],"analysis,":[71],"Y-maze":[72,167],"shuttle":[74],"box":[75],"used,":[77],"respectively":[78],"at":[79],"14":[80],"16":[82],"days":[83],"post-lesion.":[84],"histological":[86],"studies,":[87],"Nissl,":[88],"modified":[89,92],"Bielschowsky":[90],"Congo":[93],"red":[94],"staining":[95],"performed.":[97],"lesion":[99],"induced":[101],"by":[102],"injection":[103,121,138],"4":[105],"muL":[106],"ABeta":[108,119,137,141],"(1-40)":[109,120],"into":[110,122],"the":[111,116,126,130,144,153,158,211],"hippocampal":[112],"fissure.":[113],"RESULTS:":[114],"In":[115],"present":[117,209],"study,":[118],"could":[124],"decrease":[125],"indexes":[128],"number":[131],"CA1":[133,139],"neurons":[134,156],"hippocampus.":[136],"caused":[140],"deposition":[142],"less":[147],"than":[148],"cortex.":[150],"We":[151,182],"observed":[152],"cerebral":[161,212],"certain":[164],"subcortical":[165],"regions.":[166],"test":[168,173],"single-trial":[170],"passive":[171,189],"avoidance":[172,190],"showed":[174],"reduced":[175,232],"retention":[177],"AD":[179,196,229,238],"group.":[180,230,239],"CONCLUSION:":[181],"found":[183],"significant":[185],"decreased":[186],"acquisition":[187],"alternation":[192],"behavior":[193],"responses":[194],"group":[197,203],"compared":[198],"control":[200],"(P<0.0001).":[204],"Compacted":[205],"cores":[207,221],"cortex,":[213],"white":[216],"matter,":[217],"whereas,":[218],"scattered":[219],"seen":[223],"Also,":[231],"neuronal":[233],"density":[234],"indicated":[236]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":6},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}