{"id":"https://openalex.org/W2139576028","doi":"https://doi.org/10.1186/1742-2094-9-144","title":"IFN-\u03b3-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments","display_name":"IFN-\u03b3-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments","publication_year":2012,"publication_date":"2012-06-26","ids":{"openalex":"https://openalex.org/W2139576028","doi":"https://doi.org/10.1186/1742-2094-9-144","mag":"2139576028","pmid":"https://pubmed.ncbi.nlm.nih.gov/22734718","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3423045"},"language":"en","primary_location":{"id":"doi:10.1186/1742-2094-9-144","doi":"https://doi.org/10.1186/1742-2094-9-144","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1742-2094-9-144","pdf_url":"https://jneuroinflammation.biomedcentral.com/counter/pdf/10.1186/1742-2094-9-144","source":{"id":"https://openalex.org/S199572710","display_name":"Journal of Neuroinflammation","issn_l":"1742-2094","issn":["1742-2094"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroinflammation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jneuroinflammation.biomedcentral.com/counter/pdf/10.1186/1742-2094-9-144","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055433973","display_name":"Nina Vardjan","orcid":"https://orcid.org/0000-0001-8174-1668","observed_orcids":["https://orcid.org/0000-0001-8174-1668"]},"institutions":[{"id":"https://openalex.org/I153976015","display_name":"University of Ljubljana","ror":"https://ror.org/05njb9z20","country_code":"SI","type":"education","lineage":["https://openalex.org/I153976015"]},{"id":"https://openalex.org/I4210147019","display_name":"Celica (Slovenia)","ror":"https://ror.org/047h1e475","country_code":"SI","type":"company","lineage":["https://openalex.org/I4210147019"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Nina Vardjan","raw_affiliation_strings":["Celica Biomedical Center, Tehnolo\u0161ki Park 24, Ljubljana 1000, Slovenia","Laboratory of Neuroendocrinology\u2010Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Celica Biomedical Center, Tehnolo\u0161ki Park 24, Ljubljana 1000, Slovenia","institution_ids":["https://openalex.org/I4210147019"]},{"raw_affiliation_string":"Laboratory of Neuroendocrinology\u2010Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I153976015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086142826","display_name":"Mateja Gabrijel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153976015","display_name":"University of Ljubljana","ror":"https://ror.org/05njb9z20","country_code":"SI","type":"education","lineage":["https://openalex.org/I153976015"]},{"id":"https://openalex.org/I4210147019","display_name":"Celica (Slovenia)","ror":"https://ror.org/047h1e475","country_code":"SI","type":"company","lineage":["https://openalex.org/I4210147019"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Mateja Gabrijel","raw_affiliation_strings":["Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zalo\u0161ka 4, Ljubljana, 1000, Slovenia","Laboratory of Neuroendocrinology\u2010Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I4210147019"]},{"raw_affiliation_string":"Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zalo\u0161ka 4, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I153976015"]},{"raw_affiliation_string":"Laboratory of Neuroendocrinology\u2010Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I153976015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071569451","display_name":"Maja Potokar","orcid":"https://orcid.org/0000-0001-6637-0635","observed_orcids":["https://orcid.org/0000-0001-6637-0635"]},"institutions":[{"id":"https://openalex.org/I153976015","display_name":"University of Ljubljana","ror":"https://ror.org/05njb9z20","country_code":"SI","type":"education","lineage":["https://openalex.org/I153976015"]},{"id":"https://openalex.org/I4210147019","display_name":"Celica (Slovenia)","ror":"https://ror.org/047h1e475","country_code":"SI","type":"company","lineage":["https://openalex.org/I4210147019"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Maja Potokar","raw_affiliation_strings":["Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zalo\u0161ka 4, Ljubljana, 1000, Slovenia","Laboratory of Neuroendocrinology\u2010Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I4210147019"]},{"raw_affiliation_string":"Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zalo\u0161ka 4, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I153976015"]},{"raw_affiliation_string":"Laboratory of Neuroendocrinology\u2010Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I153976015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089836605","display_name":"Urban \u0160vajger","orcid":"https://orcid.org/0000-0002-1908-4254","observed_orcids":["https://orcid.org/0000-0002-1908-4254"]},"institutions":[{"id":"https://openalex.org/I4210086542","display_name":"Blood Transfusion Centre of Slovenia","ror":"https://ror.org/001s05659","country_code":"SI","type":"healthcare","lineage":["https://openalex.org/I4210086542"]},{"id":"https://openalex.org/I4210147019","display_name":"Celica (Slovenia)","ror":"https://ror.org/047h1e475","country_code":"SI","type":"company","lineage":["https://openalex.org/I4210147019"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Urban \u0160vajger","raw_affiliation_strings":["Blood Transfusion Center of Slovenia, \u0160lajmerjeva 6, Ljubljana, 1000, Slovenia","Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","Celica Biomedical Center, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Transfusion Center of Slovenia, \u0160lajmerjeva 6, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I4210086542"]},{"raw_affiliation_string":"Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I4210147019"]},{"raw_affiliation_string":"Celica Biomedical Center, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I4210147019"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089955360","display_name":"Marko Kreft","orcid":"https://orcid.org/0000-0003-4974-7052","observed_orcids":["https://orcid.org/0000-0003-4974-7052"]},"institutions":[{"id":"https://openalex.org/I153976015","display_name":"University of Ljubljana","ror":"https://ror.org/05njb9z20","country_code":"SI","type":"education","lineage":["https://openalex.org/I153976015"]},{"id":"https://openalex.org/I4210147019","display_name":"Celica (Slovenia)","ror":"https://ror.org/047h1e475","country_code":"SI","type":"company","lineage":["https://openalex.org/I4210147019"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Marko Kreft","raw_affiliation_strings":["Biotechnical Faculty, University of Ljubljana, Ve\u010dna pot 111, Ljubljana, 1000, Slovenia","Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zalo\u0161ka 4, Ljubljana, 1000, Slovenia","Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biotechnical Faculty, University of Ljubljana, Ve\u010dna pot 111, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I153976015"]},{"raw_affiliation_string":"Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I4210147019"]},{"raw_affiliation_string":"Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zalo\u0161ka 4, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I153976015"]},{"raw_affiliation_string":"Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I153976015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070232772","display_name":"Matja\u017e Jeras","orcid":"https://orcid.org/0000-0002-0992-7975","observed_orcids":["https://orcid.org/0000-0002-0992-7975"]},"institutions":[{"id":"https://openalex.org/I153976015","display_name":"University of Ljubljana","ror":"https://ror.org/05njb9z20","country_code":"SI","type":"education","lineage":["https://openalex.org/I153976015"]},{"id":"https://openalex.org/I4210086542","display_name":"Blood Transfusion Centre of Slovenia","ror":"https://ror.org/001s05659","country_code":"SI","type":"healthcare","lineage":["https://openalex.org/I4210086542"]},{"id":"https://openalex.org/I4210147019","display_name":"Celica (Slovenia)","ror":"https://ror.org/047h1e475","country_code":"SI","type":"company","lineage":["https://openalex.org/I4210147019"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Matja\u017e Jeras","raw_affiliation_strings":["Blood Transfusion Center of Slovenia, \u0160lajmerjeva 6, Ljubljana, 1000, Slovenia","Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","Faculty of Pharmacy, University of Ljubljana, A\u0161ker\u010deva cesta 5, Ljubljana, 1000, Slovenia","Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Transfusion Center of Slovenia, \u0160lajmerjeva 6, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I4210086542"]},{"raw_affiliation_string":"Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I4210147019"]},{"raw_affiliation_string":"Faculty of Pharmacy, University of Ljubljana, A\u0161ker\u010deva cesta 5, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I153976015"]},{"raw_affiliation_string":"Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I153976015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035581733","display_name":"Yolanda de Pablo","orcid":"https://orcid.org/0000-0001-5208-2114","observed_orcids":["https://orcid.org/0000-0001-5208-2114"]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Yolanda de Pablo","raw_affiliation_strings":["Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 9A, Gothenburg, 413 90, Sweden","\u2020Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 9A, Gothenburg, 413 90, Sweden","institution_ids":["https://openalex.org/I881427289"]},{"raw_affiliation_string":"\u2020Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058225296","display_name":"Maryam Faiz","orcid":"https://orcid.org/0000-0003-0671-3557","observed_orcids":["https://orcid.org/0000-0003-0671-3557"]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Maryam Faiz","raw_affiliation_strings":["Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 9A, Gothenburg, 413 90, Sweden","\u2020Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 9A, Gothenburg, 413 90, Sweden","institution_ids":["https://openalex.org/I881427289"]},{"raw_affiliation_string":"\u2020Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078058223","display_name":"Milos Pekny","orcid":"https://orcid.org/0000-0003-1607-8075","observed_orcids":["https://orcid.org/0000-0003-1607-8075"]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Milos Pekny","raw_affiliation_strings":["Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 9A, Gothenburg, 413 90, Sweden","\u2020Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 9A, Gothenburg, 413 90, Sweden","institution_ids":["https://openalex.org/I881427289"]},{"raw_affiliation_string":"\u2020Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025932270","display_name":"Robert Zorec","orcid":"https://orcid.org/0000-0002-7478-3875","observed_orcids":["https://orcid.org/0000-0002-7478-3875"]},"institutions":[{"id":"https://openalex.org/I153976015","display_name":"University of Ljubljana","ror":"https://ror.org/05njb9z20","country_code":"SI","type":"education","lineage":["https://openalex.org/I153976015"]},{"id":"https://openalex.org/I4210147019","display_name":"Celica (Slovenia)","ror":"https://ror.org/047h1e475","country_code":"SI","type":"company","lineage":["https://openalex.org/I4210147019"]}],"countries":["SI"],"is_corresponding":true,"raw_author_name":"Robert Zorec","raw_affiliation_strings":["Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zalo\u0161ka 4, Ljubljana, 1000, Slovenia","Laboratory of Neuroendocrinology\u2010Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Celica Biomedical Center, Tehnolo\u0161ki park 24, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I4210147019"]},{"raw_affiliation_string":"Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zalo\u0161ka 4, Ljubljana, 1000, Slovenia","institution_ids":["https://openalex.org/I153976015"]},{"raw_affiliation_string":"Laboratory of Neuroendocrinology\u2010Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia","institution_ids":["https://openalex.org/I153976015"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5025932270"],"corresponding_institution_ids":["https://openalex.org/I153976015","https://openalex.org/I4210147019"],"apc_list":{"value":4090,"currency":"USD","value_usd":4090},"apc_paid":{"value":4090,"currency":"USD","value_usd":4090},"fwci":2.8344,"has_fulltext":true,"cited_by_count":117,"citation_normalized_percentile":{"value":0.91124336,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"9","issue":"1","first_page":"144","last_page":"144"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.49729999899864197,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.49729999899864197,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.15029999613761902,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.08460000157356262,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9509999752044678},{"id":"https://openalex.org/keywords/mhc-class-ii","display_name":"MHC class II","score":0.859000027179718},{"id":"https://openalex.org/keywords/astrocytes","display_name":"astrocytes","score":0.9070000052452087},{"id":"https://openalex.org/keywords/intermediate-filaments","display_name":"intermediate filaments","score":0.9900000095367432},{"id":"https://openalex.org/keywords/vesicle-mobility","display_name":"vesicle mobility","score":0.8500000238418579},{"id":"https://openalex.org/keywords/late-endosomes","display_name":"late endosomes","score":0.718999981880188},{"id":"https://openalex.org/keywords/lysosomes","display_name":"lysosomes","score":0.9810000061988831},{"id":"https://openalex.org/keywords/antigen-presentation","display_name":"antigen presentation","score":0.7639999985694885},{"id":"https://openalex.org/keywords/reactive-astrocytes","display_name":"reactive astrocytes","score":0.8859999775886536},{"id":"https://openalex.org/keywords/vesicular-trafficking","display_name":"vesicle trafficking","score":0.6620000004768372},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6715279817581177},{"id":"https://openalex.org/C102747710","wikidata":"https://www.wikidata.org/wiki/Q824237","display_name":"Endosome","level":3,"score":0.6655659675598145},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.6614997386932373},{"id":"https://openalex.org/C2778814158","wikidata":"https://www.wikidata.org/wiki/Q959350","display_name":"MHC class II","level":4,"score":0.6217846870422363},{"id":"https://openalex.org/C170627219","wikidata":"https://www.wikidata.org/wiki/Q13218497","display_name":"MHC class I","level":4,"score":0.5916374921798706},{"id":"https://openalex.org/C119997001","wikidata":"https://www.wikidata.org/wiki/Q21113110","display_name":"CD74","level":5,"score":0.5763924717903137},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5655839443206787},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.5415946841239929},{"id":"https://openalex.org/C22845430","wikidata":"https://www.wikidata.org/wiki/Q224879","display_name":"Transporter associated with antigen processing","level":5,"score":0.41629138588905334},{"id":"https://openalex.org/C2777542381","wikidata":"https://www.wikidata.org/wiki/Q502961","display_name":"Astrocyte","level":3,"score":0.41203242540359497},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.37735870480537415},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2830107808113098},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.21325764060020447},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16712304949760437},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1397923231124878},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.11208710074424744},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002451","descriptor_name":"Cell Compartmentation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007381","descriptor_name":"Intermediate Filament Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007381","descriptor_name":"Intermediate Filament Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057507","descriptor_name":"Mice, 129 Strain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1186/1742-2094-9-144","doi":"https://doi.org/10.1186/1742-2094-9-144","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1742-2094-9-144","pdf_url":"https://jneuroinflammation.biomedcentral.com/counter/pdf/10.1186/1742-2094-9-144","source":{"id":"https://openalex.org/S199572710","display_name":"Journal of Neuroinflammation","issn_l":"1742-2094","issn":["1742-2094"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroinflammation","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2424831","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3423045","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3423045","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3423045","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neuroinflammation","raw_type":"Text"},{"id":"pmid:22734718","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22734718","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuroinflammation","raw_type":"Journal Article"},{"id":"pmh:oai:repozitorij.uni-lj.si:IzpisGradiva.php?id=32927","doi":null,"is_oa":true,"landing_page_url":"https://repozitorij.uni-lj.si/IzpisGradiva.php?id=32927","pdf_url":null,"source":{"id":"https://openalex.org/S4377196268","display_name":"Repository of the University of Ljubljana (University of Ljubljana)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I153976015","host_organization_name":"University of Ljubljana","host_organization_lineage":["https://openalex.org/I153976015"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuroinflammation, vol. art 144, no. 9, 2012.","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.376.2506","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.376.2506","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:debbfa92ee9d48cd817edf47f842f1da","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/debbfa92ee9d48cd817edf47f842f1da","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Neuroinflammation, Vol 9, Iss 1, p 144 (2012)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1742-2094-9-144","doi":"https://doi.org/10.1186/1742-2094-9-144","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1742-2094-9-144","pdf_url":"https://jneuroinflammation.biomedcentral.com/counter/pdf/10.1186/1742-2094-9-144","source":{"id":"https://openalex.org/S199572710","display_name":"Journal of Neuroinflammation","issn_l":"1742-2094","issn":["1742-2094"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroinflammation","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1839517495","display_name":"REGULACIJA MOBILNOSTI ASTROCITNIH SEKRETORNIH ORGANELOV PO FUZIJI Z MEMBRANO (Slovene)","funder_award_id":"J3-0133","funder_id":"https://openalex.org/F4320322554","funder_display_name":"Javna Agencija za Raziskovalno Dejavnost RS"},{"id":"https://openalex.org/G3238761143","display_name":null,"funder_award_id":"P3-310","funder_id":"https://openalex.org/F4320322554","funder_display_name":"Javna Agencija za Raziskovalno Dejavnost RS"},{"id":"https://openalex.org/G5085430756","display_name":"Targeting Brain Inflammation For Improved Functional Recovery in Acute Neurodegenerative Disorders","funder_award_id":"279017","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5948287012","display_name":"Innovative Techniques and Models to Study Glia-Neuron Interactions","funder_award_id":"237956","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G6510827793","display_name":"Dendriti\u010dne celice - pro\u017eilke in oblikovalke celi\u010dnih imunskih odzivov (Slovene)","funder_award_id":"L1-2402","funder_id":"https://openalex.org/F4320322554","funder_display_name":"Javna Agencija za Raziskovalno Dejavnost RS"},{"id":"https://openalex.org/G6941168218","display_name":"Mobilnost sekrecijskih me\u0161i\u010dkov in homeostaza kalcija v astrocitih (Slovene)","funder_award_id":"J3-4146","funder_id":"https://openalex.org/F4320322554","funder_display_name":"Javna Agencija za Raziskovalno Dejavnost RS"},{"id":"https://openalex.org/G721580940","display_name":"DINAMIKA LIZOSOMOV IN PREDSTAVITEV ANTIGENOV V ASTROCITIH (Slovene)","funder_award_id":"J3-0031","funder_id":"https://openalex.org/F4320322554","funder_display_name":"Javna Agencija za Raziskovalno Dejavnost RS"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320322554","display_name":"Javna Agencija za Raziskovalno Dejavnost RS","ror":"https://ror.org/059bp8k51"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139576028.pdf","grobid_xml":"https://content.openalex.org/works/W2139576028.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W1551925364","https://openalex.org/W1577102950","https://openalex.org/W1579103205","https://openalex.org/W1643772655","https://openalex.org/W1874238518","https://openalex.org/W1963679906","https://openalex.org/W1965917412","https://openalex.org/W1978813800","https://openalex.org/W1979848416","https://openalex.org/W1980109282","https://openalex.org/W1988866780","https://openalex.org/W1990945189","https://openalex.org/W1993029198","https://openalex.org/W1999495459","https://openalex.org/W2000488860","https://openalex.org/W2000604662","https://openalex.org/W2002302413","https://openalex.org/W2003272127","https://openalex.org/W2003870462","https://openalex.org/W2004251958","https://openalex.org/W2010672660","https://openalex.org/W2014054947","https://openalex.org/W2017593971","https://openalex.org/W2020795276","https://openalex.org/W2023967363","https://openalex.org/W2028651044","https://openalex.org/W2031096972","https://openalex.org/W2031469085","https://openalex.org/W2041112741","https://openalex.org/W2043856037","https://openalex.org/W2069705414","https://openalex.org/W2071696504","https://openalex.org/W2074138980","https://openalex.org/W2079823127","https://openalex.org/W2086225411","https://openalex.org/W2091898870","https://openalex.org/W2094854776","https://openalex.org/W2100974058","https://openalex.org/W2102089332","https://openalex.org/W2109936556","https://openalex.org/W2112405170","https://openalex.org/W2113546972","https://openalex.org/W2116100639","https://openalex.org/W2116582697","https://openalex.org/W2121042036","https://openalex.org/W2121973564","https://openalex.org/W2122821000","https://openalex.org/W2138424169","https://openalex.org/W2142142736","https://openalex.org/W2149375296","https://openalex.org/W2159765288","https://openalex.org/W2160935383","https://openalex.org/W2163520160","https://openalex.org/W4250582057"],"related_works":["https://openalex.org/W7099078581","https://openalex.org/W6991811270","https://openalex.org/W2982536269","https://openalex.org/W2004251958","https://openalex.org/W2012987505","https://openalex.org/W2414329096","https://openalex.org/W2911573602","https://openalex.org/W2116439716","https://openalex.org/W2062273553","https://openalex.org/W7143282167"],"abstract_inverted_index":{"BACKGROUND:":[0],"In":[1,263],"immune-mediated":[2],"diseases":[3],"of":[4,49,71,79,92,97,126,139,146,156,159,187,215,225,230,240,254],"the":[5,38,45,77,137,209,213,238,260],"central":[6],"nervous":[7],"system,":[8],"astrocytes":[9,87,90,106,163,203,226,272],"exposed":[10],"to":[11,34,37,75,135,259,273,281],"interferon-\u03b3":[12],"(IFN-\u03b3)":[13],"can":[14],"express":[15],"major":[16],"histocompatibility":[17],"complex":[18],"(MHC)":[19],"class":[20,29,81,99,141,168,217,256],"II":[21,30,82,100,142,169,218,257],"molecules":[22,31,258],"and":[23,47,88,104,122,161,248,276],"antigens":[24],"on":[25],"their":[26],"surface.":[27,262],"MHC":[28,80,98,140,167,216,255],"are":[32,53],"thought":[33],"be":[35],"delivered":[36],"cell":[39,261],"surface":[40],"by":[41,115],"membrane-bound":[42],"vesicles.":[43,143],"However,":[44],"characteristics":[46],"dynamics":[48],"this":[50,72],"vesicular":[51],"traffic":[52],"unclear,":[54],"particularly":[55],"in":[56,84,89,102,129,171,190,193,200,205,212,277],"reactive":[57,271],"astrocytes,":[58],"which":[59,174],"overexpress":[60],"intermediate":[61],"filament":[62],"(IF)":[63],"proteins":[64],"that":[65,237],"may":[66,268],"affect":[67],"trafficking.":[68],"The":[69,95,144],"aim":[70],"study":[73],"was":[74,112,133,148,198],"determine":[76],"mobility":[78,145,197,214],"vesicles":[83,147,189],"wild-type":[85],"(WT)":[86],"devoid":[91],"IFs.":[93],"METHODS:":[94],"identity":[96],"compartments":[101,219],"WT":[103,160,206],"IF-deficient":[105,162,202],"48":[107],"h":[108],"after":[109],"IFN-\u03b3":[110,130,165],"activation":[111],"determined":[113],"immunocytochemically":[114],"using":[116,150],"confocal":[117,120],"microscopy.":[118],"Time-lapse":[119],"imaging":[121,155,183],"Alexa":[123,179],"Fluor546-dextran":[124],"labeling":[125],"late":[127,172],"endosomes/lysosomes":[128],"treated":[131],"cells":[132],"used":[134],"characterize":[136],"motion":[138],"analyzed":[149],"ParticleTR":[151],"software.":[152],"RESULTS:":[153],"Confocal":[154],"primary":[157],"cultures":[158],"revealed":[164,184],"induced":[166],"expression":[170],"endosomes/lysosomes,":[173],"were":[175],"specifically":[176],"labeled":[177],"with":[178],"Fluor546-conjugated":[180],"dextran.":[181],"Live":[182],"faster":[185,247],"movement":[186],"dextran-positive":[188],"IFN-\u03b3-treated":[191,201],"than":[192,204],"untreated":[194],"astrocytes.":[195,207],"Vesicle":[196],"lower":[199],"Thus,":[208],"IFN-\u03b3-induced":[210],"increase":[211],"is":[220,227,235],"IF-dependent.":[221],"CONCLUSIONS:":[222],"Since":[223],"reactivity":[224],"a":[228,246,250,278],"hallmark":[229],"many":[231],"CNS":[232,282],"pathologies,":[233],"it":[234],"likely":[236],"up-regulation":[239],"IFs":[241],"under":[242],"such":[243,265],"conditions":[244],"allows":[245],"therefore":[249],"more":[251],"efficient":[252],"delivery":[253],"vivo,":[264],"regulatory":[266],"mechanisms":[267],"enable":[269],"antigen-presenting":[270],"respond":[274],"rapidly":[275],"controlled":[279],"manner":[280],"inflammation.":[283]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
