{"id":"https://openalex.org/W2139452290","doi":"https://doi.org/10.2337/dc11-2289","title":"Effects of Gastric Bypass Surgery in Patients With Type 2 Diabetes and Only Mild Obesity","display_name":"Effects of Gastric Bypass Surgery in Patients With Type 2 Diabetes and Only Mild Obesity","publication_year":2012,"publication_date":"2012-06-12","ids":{"openalex":"https://openalex.org/W2139452290","doi":"https://doi.org/10.2337/dc11-2289","mag":"2139452290","pmid":"https://pubmed.ncbi.nlm.nih.gov/22723580","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3379595"},"language":"en","primary_location":{"id":"doi:10.2337/dc11-2289","doi":"https://doi.org/10.2337/dc11-2289","is_oa":false,"landing_page_url":"https://doi.org/10.2337/dc11-2289","pdf_url":null,"source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC3379595","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063255450","display_name":"RICARDO VITOR COHEN","orcid":"https://orcid.org/0000-0001-8779-3055","observed_orcids":["https://orcid.org/0000-0001-8779-3055"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ricardo V. Cohen","raw_affiliation_strings":["The Center of Excellence in Bariatric and Metabolic Surgery, Oswaldo Cruz Hospital, and Marcia Maria Braido Hospital, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Center of Excellence in Bariatric and Metabolic Surgery, Oswaldo Cruz Hospital, and Marcia Maria Braido Hospital, S\u00e3o Paulo, Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101957284","display_name":"Jos\u00e9 Cir\u0131\u0301aco Pinheiro","orcid":"https://orcid.org/0000-0001-8376-3086","observed_orcids":["https://orcid.org/0000-0001-8376-3086"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jose C. Pinheiro","raw_affiliation_strings":["The Center of Excellence in Bariatric and Metabolic Surgery, Oswaldo Cruz Hospital, and Marcia Maria Braido Hospital, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Center of Excellence in Bariatric and Metabolic Surgery, Oswaldo Cruz Hospital, and Marcia Maria Braido Hospital, S\u00e3o Paulo, Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002926997","display_name":"Carlos Aur\u00e9lio Schiavon","orcid":"https://orcid.org/0000-0003-0798-3997","observed_orcids":["https://orcid.org/0000-0003-0798-3997"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carlos A. Schiavon","raw_affiliation_strings":["The Center of Excellence in Bariatric and Metabolic Surgery, Oswaldo Cruz Hospital, and Marcia Maria Braido Hospital, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Center of Excellence in Bariatric and Metabolic Surgery, Oswaldo Cruz Hospital, and Marcia Maria Braido Hospital, S\u00e3o Paulo, Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035992971","display_name":"Jo\u00e3o Eduardo Nunes Salles","orcid":"https://orcid.org/0000-0003-3865-5320","observed_orcids":["https://orcid.org/0000-0003-3865-5320"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jo\u00e3o E. Salles","raw_affiliation_strings":["Department of Endocrinology, Diabetes Division, Santa Casa Medical School, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Diabetes Division, Santa Casa Medical School, S\u00e3o Paulo, Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079582404","display_name":"BERNARDO LEO WAJCHENBERG","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4405258467","display_name":"Instituto do Cora\u00e7\u00e3o - HCFMUSP","ror":"https://ror.org/00q3jak84","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210145268","https://openalex.org/I4405258467"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Bernardo L. Wajchenberg","raw_affiliation_strings":["Diabetes Unit, Heart Institute, University of S\u00e3o Paulo, and Diabetes Center, Oswaldo Cruz Hospital, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Unit, Heart Institute, University of S\u00e3o Paulo, and Diabetes Center, Oswaldo Cruz Hospital, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4405258467"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111653656","display_name":"David E. Cummings","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210094549","display_name":"VA Puget Sound Health Care System","ror":"https://ror.org/00ky3az31","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210094549","https://openalex.org/I4210138024"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David E. Cummings","raw_affiliation_strings":["Diabetes and Obesity Center of Excellence and Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes and Obesity Center of Excellence and Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, Washington","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210094549"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5111653656"],"corresponding_institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210094549"],"apc_list":null,"apc_paid":null,"fwci":44.6179,"has_fulltext":false,"cited_by_count":282,"citation_normalized_percentile":{"value":0.99913823,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"35","issue":"7","first_page":"1420","last_page":"1428"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10569","display_name":"Bariatric Surgery and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10569","display_name":"Bariatric Surgery and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12053","display_name":"Minimally Invasive Surgical Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/roux-en-y-gastric-bypass","display_name":"Roux-en-Y gastric bypass","score":0.9959999918937683},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9679999947547913},{"id":"https://openalex.org/keywords/mild-obesity","display_name":"mild obesity","score":0.9079999923706055},{"id":"https://openalex.org/keywords/class-i-obesity","display_name":"class I obesity","score":0.8100000023841858},{"id":"https://openalex.org/keywords/diabetes-remission","display_name":"diabetes remission","score":0.9760000109672546},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.7009999752044678},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.871999979019165},{"id":"https://openalex.org/keywords/beta-cell-function","display_name":"beta-cell function","score":0.9049999713897705},{"id":"https://openalex.org/keywords/c-peptide","display_name":"C-peptide","score":0.9340000152587891},{"id":"https://openalex.org/keywords/cardiovascular-risk-reduction","display_name":"cardiovascular risk reduction","score":0.6869999766349792},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.8859999775886536},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9679999947547913},{"id":"https://openalex.org/keywords/long-term-surgical-outcomes","display_name":"long-term surgical outcomes","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9642406702041626},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.857418954372406},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.762188196182251},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.6838913559913635},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.6610565185546875},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6051561832427979},{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.5977573990821838},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.49973392486572266},{"id":"https://openalex.org/C2779400339","wikidata":"https://www.wikidata.org/wiki/Q1813603","display_name":"Gastric bypass surgery","level":5,"score":0.47004643082618713},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4573277235031128},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2737745940685272},{"id":"https://openalex.org/C3019402062","wikidata":"https://www.wikidata.org/wiki/Q1813603","display_name":"Gastric bypass","level":4,"score":0.2103450894355774}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006442","descriptor_name":"Glycated Hemoglobin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012074","descriptor_name":"Remission Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015390","descriptor_name":"Gastric Bypass","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.2337/dc11-2289","doi":"https://doi.org/10.2337/dc11-2289","is_oa":false,"landing_page_url":"https://doi.org/10.2337/dc11-2289","pdf_url":null,"source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2690062","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3379595","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3379595","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3379595","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"Text"},{"id":"pmid:22723580","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22723580","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes care","raw_type":"Journal Article"},{"id":"pmh:oai:www.producao.usp.br:BDPI/35862","doi":null,"is_oa":false,"landing_page_url":"http://www.producao.usp.br/handle/BDPI/35862","pdf_url":null,"source":{"id":"https://openalex.org/S4306401373","display_name":"Scientific Electronic Library Online (S\u00e3o Paulo Research Foundation, Latin American and Caribbean Center on Health Sciences Information, Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2982035970","host_organization_name":"Costa Rican Department of Social Security","host_organization_lineage":["https://openalex.org/I2982035970"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.920.3138","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.920.3138","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://care.diabetesjournals.org/content/diacare/35/7/1420.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2690062","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3379595","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8799999952316284,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W181163628","https://openalex.org/W1534052272","https://openalex.org/W1558000543","https://openalex.org/W1977865432","https://openalex.org/W1987334833","https://openalex.org/W1997594107","https://openalex.org/W1998186571","https://openalex.org/W1999414774","https://openalex.org/W2019991064","https://openalex.org/W2025588013","https://openalex.org/W2031484324","https://openalex.org/W2036910859","https://openalex.org/W2037186223","https://openalex.org/W2038034590","https://openalex.org/W2057194981","https://openalex.org/W2058878445","https://openalex.org/W2059838547","https://openalex.org/W2064355028","https://openalex.org/W2066885372","https://openalex.org/W2067832262","https://openalex.org/W2091289879","https://openalex.org/W2093458291","https://openalex.org/W2093587125","https://openalex.org/W2096321805","https://openalex.org/W2101316711","https://openalex.org/W2104183837","https://openalex.org/W2106127587","https://openalex.org/W2107640386","https://openalex.org/W2109954844","https://openalex.org/W2110791445","https://openalex.org/W2117191092","https://openalex.org/W2139080271","https://openalex.org/W2146343227","https://openalex.org/W2166693613","https://openalex.org/W2170005843","https://openalex.org/W2171520458","https://openalex.org/W2171606604","https://openalex.org/W2520432709","https://openalex.org/W2608243249","https://openalex.org/W4241883936","https://openalex.org/W4255513322","https://openalex.org/W4302127682","https://openalex.org/W6649891809","https://openalex.org/W6673748845"],"related_works":["https://openalex.org/W2237521915","https://openalex.org/W2914723344","https://openalex.org/W2924352134","https://openalex.org/W2023669113","https://openalex.org/W2159525812","https://openalex.org/W2743445171","https://openalex.org/W2002755520","https://openalex.org/W3011298227","https://openalex.org/W1990667704","https://openalex.org/W3036583973"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Roux-en-Y":[1],"gastric":[2],"bypass":[3],"(RYGB)":[4],"ameliorates":[5],"type":[6],"2":[7],"diabetes":[8,37,90,95,119,132,159,248],"in":[9,58,122,135,142,162,213,255],"severely":[10],"obese":[11,24],"patients":[12,35,51,88,239,256],"through":[13],"mechanisms":[14,181],"beyond":[15],"just":[16],"weight":[17,203],"loss,":[18],"and":[19,38,62,84,110,206,221,226,245,249],"it":[20],"may":[21],"benefit":[22],"less":[23],"diabetic":[25,50,238],"patients.":[26],"We":[27],"determined":[28],"the":[29,85,163,231],"long-term":[30],"impact":[31],"of":[32,87,137,173,182,219,260],"RYGB":[33,57,236,243],"on":[34],"with":[36,52,76,103,139,170,178,257],"only":[39,261],"class":[40],"I":[41],"obesity.":[42,242],"RESEARCH":[43],"DESIGN":[44],"AND":[45],"METHODS:":[46],"Sixty-six":[47],"consecutively":[48],"selected":[49],"BMI":[53,259],"30-35":[54,262],"kg/m(2)":[55],"underwent":[56],"a":[59,258],"tertiary-care":[60],"hospital":[61],"were":[63,82],"prospectively":[64],"studied":[65],"for":[66,237],"up":[67,125],"to":[68,126,151,168,186],"6":[69,127],"years":[70,73,109,128],"(median":[71],"5":[72],"[range":[74],"1-6]),":[75],"100%":[77],"follow-up.":[78],"Main":[79],"outcome":[80],"measures":[81,172],"safety":[83],"percentage":[86],"experiencing":[89],"remission":[91,133],"(HbA(1c)":[92],"<6.5%":[93],"without":[94,240],"medication).":[96],"RESULTS:":[97],"Participants":[98],"had":[99],"severe,":[100],"longstanding":[101],"diabetes,":[102],"disease":[104,217,225],"duration":[105],"12.5":[106],"\u00b1":[107,113,149,153],"7.4":[108],"HbA(1c)":[111,145],"9.7":[112,148],"1.5%,":[114],"despite":[115,158],"insulin":[116],"and/or":[117],"oral":[118],"medication":[120,160],"usage":[121],"everyone.":[123],"For":[124],"following":[129],"RYGB,":[130],"durable":[131],"occurred":[134],"88%":[136],"cases,":[138],"glycemic":[140],"improvement":[141],"11%.":[143],"Mean":[144],"fell":[146],"from":[147],"1.5":[150],"5.9":[152],"0.1%":[154],"(P":[155],"<":[156],"0.001),":[157],"cessation":[161],"majority.":[164],"Weight":[165],"loss":[166],"failed":[167],"correlate":[169],"several":[171],"improved":[174,191],"glucose":[175,187],"homeostasis,":[176],"consistent":[177],"weight-independent":[179],"antidiabetes":[180],"RYGB.":[183],"C-peptide":[184],"responses":[185],"increased":[188],"substantially,":[189],"suggesting":[190],"\u03b2-cell":[192],"function.":[193],"There":[194],"was":[195],"no":[196],"mortality,":[197],"major":[198],"surgical":[199],"morbidity,":[200],"or":[201],"excessive":[202],"loss.":[204],"Hypertension":[205],"dyslipidemia":[207],"also":[208],"improved,":[209],"yielding":[210],"50-84%":[211],"reductions":[212],"predicted":[214],"10-year":[215],"cardiovascular":[216,253],"risks":[218],"fatal":[220],"nonfatal":[222],"coronary":[223],"heart":[224],"stroke.":[227],"CONCLUSIONS:":[228],"This":[229],"is":[230],"largest,":[232],"longest-term":[233],"study":[234],"examining":[235],"severe":[241],"safely":[244],"effectively":[246],"ameliorated":[247],"associated":[250],"comorbidities,":[251],"reducing":[252],"risk,":[254],"kg/m(2).":[263]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":21},{"year":2017,"cited_by_count":24},{"year":2016,"cited_by_count":36},{"year":2015,"cited_by_count":38},{"year":2014,"cited_by_count":47},{"year":2013,"cited_by_count":43},{"year":2012,"cited_by_count":9}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}