{"id":"https://openalex.org/W2139381318","doi":"https://doi.org/10.1074/jbc.275.13.9797","title":"RbAp48 Belongs to the Histone Deacetylase Complex That Associates with the Retinoblastoma Protein","display_name":"RbAp48 Belongs to the Histone Deacetylase Complex That Associates with the Retinoblastoma Protein","publication_year":2000,"publication_date":"2000-03-01","ids":{"openalex":"https://openalex.org/W2139381318","doi":"https://doi.org/10.1074/jbc.275.13.9797","mag":"2139381318","pmid":"https://pubmed.ncbi.nlm.nih.gov/10734134"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.275.13.9797","doi":"https://doi.org/10.1074/jbc.275.13.9797","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.275.13.9797","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.275.13.9797","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041312363","display_name":"Estelle Nicolas","orcid":"https://orcid.org/0000-0003-0412-8477","observed_orcids":["https://orcid.org/0000-0003-0412-8477"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210146969","display_name":"Laboratoire de Biologie Mol\u00e9culaire des Eucaryotes","ror":"https://ror.org/04zmms242","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I134560555","https://openalex.org/I4210096427","https://openalex.org/I4210146969","https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Estelle Nicolas","raw_affiliation_strings":["Laboratoire de Biologie Mol\u00e9culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biologie Mol\u00e9culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210146969"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112897399","display_name":"Violette Morales","orcid":"https://orcid.org/0009-0008-8868-5273","observed_orcids":["https://orcid.org/0009-0008-8868-5273"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210146969","display_name":"Laboratoire de Biologie Mol\u00e9culaire des Eucaryotes","ror":"https://ror.org/04zmms242","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I134560555","https://openalex.org/I4210096427","https://openalex.org/I4210146969","https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Violette Morales","raw_affiliation_strings":["Laboratoire de Biologie Mole\u0301culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France","Laboratoire de Biologie Mol\u00e9culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biologie Mole\u0301culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210146969"]},{"raw_affiliation_string":"Laboratoire de Biologie Mol\u00e9culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210146969"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014206766","display_name":"Laura Magnaghi-Jaulin","orcid":"https://orcid.org/0000-0002-5751-9802","observed_orcids":["https://orcid.org/0000-0002-5751-9802"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laura Magnaghi-Jaulin","raw_affiliation_strings":["Laboratoire \u201cOncoge\u0301ne\u0300se, Diffe\u0301renciation et Transduction du Signal,\u201d CNRS UPR 9079, IFC-01, 94801 Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire \u201cOncoge\u0301ne\u0300se, Diffe\u0301renciation et Transduction du Signal,\u201d CNRS UPR 9079, IFC-01, 94801 Villejuif, France","institution_ids":["https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086819088","display_name":"Annick Harel\u2010Bellan","orcid":"https://orcid.org/0000-0002-2339-153X","observed_orcids":["https://orcid.org/0000-0002-2339-153X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Annick Harel-Bellan","raw_affiliation_strings":["Laboratoire \u201cOncoge\u0301ne\u0300se, Diffe\u0301renciation et Transduction du Signal,\u201d CNRS UPR 9079, IFC-01, 94801 Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire \u201cOncoge\u0301ne\u0300se, Diffe\u0301renciation et Transduction du Signal,\u201d CNRS UPR 9079, IFC-01, 94801 Villejuif, France","institution_ids":["https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109202564","display_name":"H\u00e9l\u00e8ne Richard\u2010Foy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210146969","display_name":"Laboratoire de Biologie Mol\u00e9culaire des Eucaryotes","ror":"https://ror.org/04zmms242","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I134560555","https://openalex.org/I4210096427","https://openalex.org/I4210146969","https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"H\u00e9l\u00e8ne Richard-Foy","raw_affiliation_strings":["Laboratoire de Biologie Mole\u0301culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France","Laboratoire de Biologie Mol\u00e9culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biologie Mole\u0301culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210146969"]},{"raw_affiliation_string":"Laboratoire de Biologie Mol\u00e9culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210146969"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005399812","display_name":"Didier Trouche","orcid":"https://orcid.org/0000-0003-1398-6481","observed_orcids":["https://orcid.org/0000-0003-1398-6481"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210146969","display_name":"Laboratoire de Biologie Mol\u00e9culaire des Eucaryotes","ror":"https://ror.org/04zmms242","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I134560555","https://openalex.org/I4210096427","https://openalex.org/I4210146969","https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Didier Trouche","raw_affiliation_strings":["Laboratoire de Biologie Mole\u0301culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France","Laboratoire de Biologie Mol\u00e9culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biologie Mole\u0301culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210146969"]},{"raw_affiliation_string":"Laboratoire de Biologie Mol\u00e9culaire Eucaryote, UPR 9006 CNRS, 118 route de Narbonne, 31 062 Toulouse Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210146969"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":2.986,"has_fulltext":false,"cited_by_count":122,"citation_normalized_percentile":{"value":0.92213459,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"275","issue":"13","first_page":"9797","last_page":"9804"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11736","display_name":"Histone Deacetylase Inhibitors Research","score":0.5503000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11736","display_name":"Histone Deacetylase Inhibitors Research","score":0.5503000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.34200000762939453,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.03319999948143959,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rbap48","display_name":"RbAp48","score":0.9990000128746033},{"id":"https://openalex.org/keywords/retinoblastoma-protein","display_name":"retinoblastoma protein","score":0.9319999814033508},{"id":"https://openalex.org/keywords/histone-deacetylase-complex","display_name":"histone deacetylase complex","score":0.8769999742507935},{"id":"https://openalex.org/keywords/hdac1","display_name":"HDAC1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/transcriptional-repression","display_name":"transcriptional repression","score":0.8209999799728394},{"id":"https://openalex.org/keywords/e2f1","display_name":"E2F1","score":0.8859999775886536},{"id":"https://openalex.org/keywords/e2f-transcription-factors","display_name":"E2F transcription factors","score":0.734000027179718},{"id":"https://openalex.org/keywords/cell-cycle-regulation","display_name":"cell cycle regulation","score":0.7649999856948853},{"id":"https://openalex.org/keywords/protein-complex-assembly","display_name":"protein complex formation","score":0.6259999871253967},{"id":"https://openalex.org/keywords/histone-deacetylation","display_name":"histone deacetylation","score":0.796999990940094}],"concepts":[{"id":"https://openalex.org/C4951695","wikidata":"https://www.wikidata.org/wiki/Q18046437","display_name":"HDAC11","level":5,"score":0.7139996290206909},{"id":"https://openalex.org/C27253355","wikidata":"https://www.wikidata.org/wiki/Q18034954","display_name":"Histone deacetylase 5","level":5,"score":0.71087646484375},{"id":"https://openalex.org/C58793620","wikidata":"https://www.wikidata.org/wiki/Q21173206","display_name":"HDAC4","level":5,"score":0.6785551905632019},{"id":"https://openalex.org/C2778305200","wikidata":"https://www.wikidata.org/wiki/Q174378","display_name":"Histone deacetylase","level":4,"score":0.6543552279472351},{"id":"https://openalex.org/C45946802","wikidata":"https://www.wikidata.org/wiki/Q18033449","display_name":"SAP30","level":5,"score":0.6260372996330261},{"id":"https://openalex.org/C71723506","wikidata":"https://www.wikidata.org/wiki/Q18026859","display_name":"Histone deacetylase 2","level":5,"score":0.6140913963317871},{"id":"https://openalex.org/C142354902","wikidata":"https://www.wikidata.org/wiki/Q18047334","display_name":"HDAC10","level":5,"score":0.5832337141036987},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.46091726422309875},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.43470314145088196},{"id":"https://openalex.org/C85240754","wikidata":"https://www.wikidata.org/wiki/Q14914420","display_name":"HDAC1","level":5,"score":0.4224078357219696},{"id":"https://openalex.org/C2779085176","wikidata":"https://www.wikidata.org/wiki/Q24721644","display_name":"Histone H4","level":4,"score":0.42165112495422363},{"id":"https://openalex.org/C83258922","wikidata":"https://www.wikidata.org/wiki/Q24771933","display_name":"E2F","level":4,"score":0.41827917098999023},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38867831230163574},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.36595070362091064},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3349657952785492},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.2741733193397522},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.23893532156944275},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18593838810920715},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08185097575187683}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006655","descriptor_name":"Histone Deacetylases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009687","descriptor_name":"Nuclear Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012175","descriptor_name":"Retinoblastoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016160","descriptor_name":"Retinoblastoma Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016193","descriptor_name":"G1 Phase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018797","descriptor_name":"Cell Cycle Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D050680","descriptor_name":"Transcription Factor DP1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050684","descriptor_name":"E2F Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050687","descriptor_name":"E2F1 Transcription Factor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056465","descriptor_name":"Retinoblastoma-Binding Protein 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056505","descriptor_name":"Retinoblastoma-Binding Protein 4","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1074/jbc.275.13.9797","doi":"https://doi.org/10.1074/jbc.275.13.9797","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.275.13.9797","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:10734134","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10734134","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04298278v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-04298278","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Biological Chemistry, 2000, 275 (13), pp.9797-9804. ⟨10.1074/jbc.275.13.9797⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1074/jbc.275.13.9797","doi":"https://doi.org/10.1074/jbc.275.13.9797","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.275.13.9797","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W5406636","https://openalex.org/W88518327","https://openalex.org/W327522344","https://openalex.org/W1042129104","https://openalex.org/W1525573602","https://openalex.org/W1606907359","https://openalex.org/W1635667563","https://openalex.org/W1665024321","https://openalex.org/W1771253106","https://openalex.org/W1911118961","https://openalex.org/W1923050340","https://openalex.org/W1932232742","https://openalex.org/W1937375640","https://openalex.org/W1973672022","https://openalex.org/W1974112332","https://openalex.org/W1978116091","https://openalex.org/W1980759602","https://openalex.org/W1985626007","https://openalex.org/W1990726449","https://openalex.org/W1993243592","https://openalex.org/W1994840092","https://openalex.org/W2007884336","https://openalex.org/W2021719977","https://openalex.org/W2026393778","https://openalex.org/W2026441085","https://openalex.org/W2029954359","https://openalex.org/W2031203111","https://openalex.org/W2032623141","https://openalex.org/W2040056274","https://openalex.org/W2040506727","https://openalex.org/W2043064096","https://openalex.org/W2045985961","https://openalex.org/W2052381578","https://openalex.org/W2054208176","https://openalex.org/W2055270107","https://openalex.org/W2055597783","https://openalex.org/W2061305387","https://openalex.org/W2063409224","https://openalex.org/W2069681995","https://openalex.org/W2071373462","https://openalex.org/W2071981322","https://openalex.org/W2080810925","https://openalex.org/W2085615781","https://openalex.org/W2086948825","https://openalex.org/W2095115211","https://openalex.org/W2095555808","https://openalex.org/W2098470595","https://openalex.org/W2098727578","https://openalex.org/W2105902888","https://openalex.org/W2109340318","https://openalex.org/W2112425896","https://openalex.org/W2120606561","https://openalex.org/W2132440338","https://openalex.org/W2146822181","https://openalex.org/W2151513082","https://openalex.org/W2168146428","https://openalex.org/W2169183151","https://openalex.org/W2169817991","https://openalex.org/W2324266222","https://openalex.org/W2334062824","https://openalex.org/W2416126290","https://openalex.org/W3026147203"],"related_works":["https://openalex.org/W2114108390","https://openalex.org/W1635667563","https://openalex.org/W1665024321","https://openalex.org/W2095115211","https://openalex.org/W88152516","https://openalex.org/W2149706478","https://openalex.org/W2011218103","https://openalex.org/W1639774682","https://openalex.org/W7096548061","https://openalex.org/W2112425896"],"abstract_inverted_index":{"The":[0,98],"retinoblastoma":[1],"susceptibility":[2],"gene":[3],"product,":[4],"the":[5,18,24,37,52,68,79,112,120,171,189],"Rb":[6,22,35,45,64,127,138,192],"protein,":[7],"is":[8,23,46,116,167],"a":[9,71,123,168],"key":[10],"regulator":[11],"of":[12,17,21,39,55,70,122,170,191,204],"mammalian":[13],"cell":[14,56,140],"proliferation.":[15],"One":[16],"major":[19],"targets":[20],"S":[25],"phase":[26],"inducing":[27],"E2F":[28],"transcription":[29,66],"factor.":[30],"Once":[31],"bound":[32],"to":[33,48,103,118],"E2F,":[34],"represses":[36,65],"expression":[38],"E2F-regulated":[40],"genes.":[41,206],"Transcriptional":[42],"repression":[43,203],"by":[44,176],"believed":[47],"be":[49,93,199],"crucial":[50],"for":[51,143],"proper":[53],"control":[54],"growth.":[57],"Recently,":[58],"we":[59,75,179],"and":[60,128,152,183,193],"others":[61],"showed":[62],"that":[63,78,89,111,148,165,181,196],"through":[67],"recruitment":[69],"histone":[72,81,105,113,150,172],"deacetylase.":[73],"Interestingly,":[74],"show":[76,109],"here":[77,110],"Rb-associated":[80,99],"deacetylase":[82,106,114,132,173],"complex":[83,125,174],"could":[84,92,198],"deacetylate":[85],"polynucleosomal":[86],"substrates,":[87],"indicating":[88],"other":[90],"proteins":[91],"present":[94],"within":[95],"this":[96],"complex.":[97],"protein":[100],"RbAp48":[101,144,153,166,184,197],"belongs":[102],"many":[104],"complexes.":[107],"We":[108],"HDAC1":[115],"able":[117],"mediate":[119],"formation":[121],"ternary":[124],"containing":[126,145],"RbAp48.":[129],"Moreover,":[130],"less":[131],"activity":[133],"was":[134],"found":[135,180],"associated":[136,156,187],"with":[137],"in":[139,157,188,201],"extracts":[141],"depleted":[142],"complexes,":[146],"demonstrating":[147],"Rb,":[149],"deacetylase,":[151],"are":[154,185],"physically":[155,186],"live":[158],"cells.":[159],"Taken":[160],"together,":[161],"these":[162],"data":[163],"indicate":[164],"component":[169],"recruited":[175],"Rb.":[177],"Finally,":[178],"E2F1":[182],"presence":[190],"HDAC1,":[194],"suggesting":[195],"involved":[200],"transcriptional":[202],"E2F-responsive":[205]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}