{"id":"https://openalex.org/W2139353459","doi":"https://doi.org/10.1242/dev.02331","title":"The LEAFY target LMI1 is a meristem identity regulator and acts together with LEAFY to regulate expression of CAULIFLOWER","display_name":"The LEAFY target LMI1 is a meristem identity regulator and acts together with LEAFY to regulate expression of CAULIFLOWER","publication_year":2006,"publication_date":"2006-03-22","ids":{"openalex":"https://openalex.org/W2139353459","doi":"https://doi.org/10.1242/dev.02331","mag":"2139353459","pmid":"https://pubmed.ncbi.nlm.nih.gov/16554366"},"language":"en","primary_location":{"id":"doi:10.1242/dev.02331","doi":"https://doi.org/10.1242/dev.02331","is_oa":false,"landing_page_url":"https://doi.org/10.1242/dev.02331","pdf_url":null,"source":{"id":"https://openalex.org/S86558740","display_name":"Development","issn_l":"0950-1991","issn":["0950-1991","1477-9129"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311847","host_organization_name":"The Company of Biologists","host_organization_lineage":["https://openalex.org/P4310311847"],"host_organization_lineage_names":["The Company of Biologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2139353459"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017247435","display_name":"Louis Saddic","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Louis A. Saddic","raw_affiliation_strings":["Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073405344","display_name":"B\u00e4rbel Huvermann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ba\u0308rbel Huvermann","raw_affiliation_strings":["Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039578728","display_name":"Staver Bezhani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Staver Bezhani","raw_affiliation_strings":["Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078621019","display_name":"Yanhui Su","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yanhui Su","raw_affiliation_strings":["Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041773699","display_name":"Cara M. Winter","orcid":"https://orcid.org/0009-0003-1525-7028","observed_orcids":["https://orcid.org/0009-0003-1525-7028"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cara M. Winter","raw_affiliation_strings":["Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chang Seob Kwon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chang Seob Kwon","raw_affiliation_strings":["Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057126315","display_name":"Richard P. Collum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard P. Collum","raw_affiliation_strings":["Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040273544","display_name":"Doris Wagner","orcid":"https://orcid.org/0000-0003-4656-2490","observed_orcids":["https://orcid.org/0000-0003-4656-2490"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Doris Wagner","raw_affiliation_strings":["Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5040273544"],"corresponding_institution_ids":["https://openalex.org/I79576946"],"apc_list":null,"apc_paid":null,"fwci":18.3275,"has_fulltext":false,"cited_by_count":207,"citation_normalized_percentile":{"value":0.99427624,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"133","issue":"9","first_page":"1673","last_page":"1682"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12475","display_name":"Plant Parasitism and Resistance","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leafy","display_name":"LEAFY","score":0.9470000267028809},{"id":"https://openalex.org/keywords/cauliflower","display_name":"cauliflower","score":0.9769999980926514},{"id":"https://openalex.org/keywords/meristem-identity","display_name":"meristem identity","score":0.8899999856948853},{"id":"https://openalex.org/keywords/vegetative-to-reproductive-transition","display_name":"vegetative to reproductive transition","score":0.8130000233650208},{"id":"https://openalex.org/keywords/leaf-morphogenesis","display_name":"leaf morphogenesis","score":0.7319999933242798},{"id":"https://openalex.org/keywords/apetala1","display_name":"APETALA1","score":0.7250000238418579},{"id":"https://openalex.org/keywords/direct-transcriptional-targets","display_name":"direct transcriptional targets","score":0.6669999957084656},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.8899999856948853}],"concepts":[{"id":"https://openalex.org/C2781451354","wikidata":"https://www.wikidata.org/wiki/Q6508901","display_name":"Leafy","level":2,"score":0.9443475604057312},{"id":"https://openalex.org/C126021549","wikidata":"https://www.wikidata.org/wiki/Q207604","display_name":"Meristem","level":3,"score":0.9285396337509155},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9172561168670654},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.7044262886047363},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.6580603122711182},{"id":"https://openalex.org/C22752065","wikidata":"https://www.wikidata.org/wiki/Q729496","display_name":"Bract","level":3,"score":0.52630615234375},{"id":"https://openalex.org/C6929976","wikidata":"https://www.wikidata.org/wiki/Q3771881","display_name":"Regulator","level":3,"score":0.5092376470565796},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5046893358230591},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.4696364104747772},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.44935959577560425},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.26333922147750854},{"id":"https://openalex.org/C178165689","wikidata":"https://www.wikidata.org/wiki/Q156428","display_name":"Inflorescence","level":2,"score":0.19280028343200684},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.1365276277065277}],"mesh":[{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018398","descriptor_name":"Homeodomain Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018519","descriptor_name":"Meristem","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018519","descriptor_name":"Meristem","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D026161","descriptor_name":"MADS Domain Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1242/dev.02331","doi":"https://doi.org/10.1242/dev.02331","is_oa":false,"landing_page_url":"https://doi.org/10.1242/dev.02331","pdf_url":null,"source":{"id":"https://openalex.org/S86558740","display_name":"Development","issn_l":"0950-1991","issn":["0950-1991","1477-9129"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311847","host_organization_name":"The Company of Biologists","host_organization_lineage":["https://openalex.org/P4310311847"],"host_organization_lineage_names":["The Company of Biologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development","raw_type":"journal-article"},{"id":"pmid:16554366","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16554366","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development (Cambridge, England)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.5365999937057495,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W1516506193","https://openalex.org/W1524952049","https://openalex.org/W1553017085","https://openalex.org/W1594494166","https://openalex.org/W1806483557","https://openalex.org/W1952267772","https://openalex.org/W1964902825","https://openalex.org/W1966034049","https://openalex.org/W1972452632","https://openalex.org/W1976021793","https://openalex.org/W1989334420","https://openalex.org/W1995907191","https://openalex.org/W2002212941","https://openalex.org/W2003020245","https://openalex.org/W2004901782","https://openalex.org/W2006662238","https://openalex.org/W2014614979","https://openalex.org/W2014738779","https://openalex.org/W2023222706","https://openalex.org/W2025937395","https://openalex.org/W2028045487","https://openalex.org/W2028191583","https://openalex.org/W2032117740","https://openalex.org/W2032805330","https://openalex.org/W2034015100","https://openalex.org/W2039401054","https://openalex.org/W2041122198","https://openalex.org/W2053427298","https://openalex.org/W2062907669","https://openalex.org/W2063914695","https://openalex.org/W2064924181","https://openalex.org/W2065692248","https://openalex.org/W2070801275","https://openalex.org/W2074411294","https://openalex.org/W2076052809","https://openalex.org/W2082903714","https://openalex.org/W2093929458","https://openalex.org/W2096451658","https://openalex.org/W2098045561","https://openalex.org/W2098115340","https://openalex.org/W2109110326","https://openalex.org/W2110699703","https://openalex.org/W2111506290","https://openalex.org/W2113057324","https://openalex.org/W2118472374","https://openalex.org/W2118542550","https://openalex.org/W2124115103","https://openalex.org/W2124394546","https://openalex.org/W2124819931","https://openalex.org/W2125503823","https://openalex.org/W2125669327","https://openalex.org/W2126089568","https://openalex.org/W2126602684","https://openalex.org/W2134594231","https://openalex.org/W2135597868","https://openalex.org/W2136081947","https://openalex.org/W2140540924","https://openalex.org/W2142204601","https://openalex.org/W2145721324","https://openalex.org/W2147835081","https://openalex.org/W2151626768","https://openalex.org/W2151839035","https://openalex.org/W2153624566","https://openalex.org/W2153891726","https://openalex.org/W2155186053","https://openalex.org/W2185641004","https://openalex.org/W2214375410"],"related_works":["https://openalex.org/W1989334420","https://openalex.org/W1519499210","https://openalex.org/W2159592439","https://openalex.org/W2126089568","https://openalex.org/W7095788620","https://openalex.org/W2124819931","https://openalex.org/W1951020966","https://openalex.org/W2032805330","https://openalex.org/W2115680749","https://openalex.org/W2751879590"],"abstract_inverted_index":{"The":[0,15,97,130],"timing":[1],"of":[2,36,66,73,119,127,135],"the":[3,33,58,75,117,125],"switch":[4,27],"from":[5],"vegetative":[6],"to":[7,93],"reproductive":[8],"development":[9],"is":[10,83],"crucial":[11],"for":[12,57],"species":[13],"survival.":[14],"plant-specific":[16],"transcription":[17,80],"factor":[18,81],"and":[19,44,102,123,132,143],"meristem":[20,39,60,85,141],"identity":[21,40,61,86,142],"regulator":[22],"LEAFY":[23],"(LFY)":[24],"controls":[25],"this":[26],"in":[28,30,116,124,140],"Arabidopsis,":[29],"part":[31],"via":[32],"direct":[34,52],"activation":[35],"two":[37],"other":[38],"genes,":[41],"APETALA1":[42],"(AP1)":[43],"CAULIFLOWER":[45],"(CAL).":[46],"We":[47],"recently":[48],"identified":[49],"five":[50],"new":[51],"LFY":[53,92],"targets":[54],"as":[55],"candidates":[56],"missing":[59],"regulators":[62],"that":[63,71],"act":[64],"downstream":[65],"LFY.":[67],"Here,":[68],"we":[69],"demonstrate":[70],"one":[72],"these,":[74],"class":[76],"I":[77],"homeodomain":[78],"leucine-zipper":[79],"LMI1,":[82],"a":[84,105,138],"regulator.":[87],"LMI1":[88,101,111,136],"acts":[89],"together":[90],"with":[91],"activate":[94],"CAL":[95,103],"expression.":[96],"interaction":[98],"between":[99],"LFY,":[100],"resembles":[104],"feed-forward":[106],"loop":[107],"transcriptional":[108],"network":[109],"motif.":[110],"has":[112],"additional":[113],"LFY-independent":[114],"roles":[115],"formation":[118],"simple":[120],"serrated":[121],"leaves":[122],"suppression":[126],"bract":[128],"formation.":[129],"temporal":[131],"spatial":[133],"expression":[134],"supports":[137],"role":[139],"leaf/bract":[144],"morphogenesis.":[145]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":17},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}