{"id":"https://openalex.org/W2139307405","doi":"https://doi.org/10.3109/15412555.2012.684414","title":"Alcohol Use Predicts ER Visits in Individuals with Alpha-1 Antitrypsin Deficiency (AATD) Associated COPD","display_name":"Alcohol Use Predicts ER Visits in Individuals with Alpha-1 Antitrypsin Deficiency (AATD) Associated COPD","publication_year":2012,"publication_date":"2012-05-31","ids":{"openalex":"https://openalex.org/W2139307405","doi":"https://doi.org/10.3109/15412555.2012.684414","mag":"2139307405","pmid":"https://pubmed.ncbi.nlm.nih.gov/22651849","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3603142"},"language":"en","primary_location":{"id":"doi:10.3109/15412555.2012.684414","doi":"https://doi.org/10.3109/15412555.2012.684414","is_oa":true,"landing_page_url":"https://doi.org/10.3109/15412555.2012.684414","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/15412555.2012.684414?needAccess=true&role=button","source":{"id":"https://openalex.org/S15387528","display_name":"COPD Journal of Chronic Obstructive Pulmonary Disease","issn_l":"1541-2555","issn":["1541-2555","1541-2563"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.3109/15412555.2012.684414?needAccess=true&role=button","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007566739","display_name":"Karin Ferneyhough Hoth","orcid":"https://orcid.org/0000-0002-4261-5308","observed_orcids":["https://orcid.org/0000-0002-4261-5308"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Karin F. Hoth","raw_affiliation_strings":["1National Jewish Health, Department of Medicine,\rDenver, CO, United States","2University of Colorado School of Medicine, Department of Psychiatry,\rDenver, CO, United States","3University of Colorado School of Medicine, Department of Neurology,\rDenver, CO, United States","National Jewish Health, Department of Medicine, Denver, CO, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1National Jewish Health, Department of Medicine,\rDenver, CO, United States","institution_ids":["https://openalex.org/I3019586173"]},{"raw_affiliation_string":"2University of Colorado School of Medicine, Department of Psychiatry,\rDenver, CO, United States","institution_ids":["https://openalex.org/I921990950"]},{"raw_affiliation_string":"3University of Colorado School of Medicine, Department of Neurology,\rDenver, CO, United States","institution_ids":["https://openalex.org/I921990950"]},{"raw_affiliation_string":"National Jewish Health, Department of Medicine, Denver, CO, United States","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065913667","display_name":"Dee Walker Ford","orcid":"https://orcid.org/0000-0002-3846-6848","observed_orcids":["https://orcid.org/0000-0002-3846-6848"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dee W. Ford","raw_affiliation_strings":["4Medical University of South Carolina, Department of Pulmonary and Critical Care Medicine,\rCharleston, SC, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Medical University of South Carolina, Department of Pulmonary and Critical Care Medicine,\rCharleston, SC, United States","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057800275","display_name":"Robert A. Sandhaus","orcid":"https://orcid.org/0000-0002-7937-2485","observed_orcids":["https://orcid.org/0000-0002-7937-2485"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Sandhaus","raw_affiliation_strings":["1National Jewish Health, Department of Medicine,\rDenver, CO, United States","National Jewish Health, Department of Medicine, Denver, CO, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1National Jewish Health, Department of Medicine,\rDenver, CO, United States","institution_ids":["https://openalex.org/I3019586173"]},{"raw_affiliation_string":"National Jewish Health, Department of Medicine, Denver, CO, United States","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006886866","display_name":"Charlie Strange","orcid":"https://orcid.org/0000-0002-8109-8067","observed_orcids":["https://orcid.org/0000-0002-8109-8067"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charlie Strange","raw_affiliation_strings":["4Medical University of South Carolina, Department of Pulmonary and Critical Care Medicine,\rCharleston, SC, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Medical University of South Carolina, Department of Pulmonary and Critical Care Medicine,\rCharleston, SC, United States","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112776933","display_name":"Frederick S. Wamboldt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frederick S. Wamboldt","raw_affiliation_strings":["1National Jewish Health, Department of Medicine,\rDenver, CO, United States","2University of Colorado School of Medicine, Department of Psychiatry,\rDenver, CO, United States","2University of Colorado School of Medicine, Department of Psychiatry,#R#Denver, CO, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1National Jewish Health, Department of Medicine,\rDenver, CO, United States","institution_ids":["https://openalex.org/I3019586173"]},{"raw_affiliation_string":"2University of Colorado School of Medicine, Department of Psychiatry,\rDenver, CO, United States","institution_ids":["https://openalex.org/I921990950"]},{"raw_affiliation_string":"2University of Colorado School of Medicine, Department of Psychiatry,#R#Denver, CO, United States","institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064431969","display_name":"Kristen E. Holm","orcid":"https://orcid.org/0000-0003-2280-2322","observed_orcids":["https://orcid.org/0000-0003-2280-2322"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristen E. Holm","raw_affiliation_strings":["1National Jewish Health, Department of Medicine,\rDenver, CO, United States","National Jewish Health, Department of Medicine, Denver, CO, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1National Jewish Health, Department of Medicine,\rDenver, CO, United States","institution_ids":["https://openalex.org/I3019586173"]},{"raw_affiliation_string":"National Jewish Health, Department of Medicine, Denver, CO, United States","institution_ids":["https://openalex.org/I3019586173"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5007566739"],"corresponding_institution_ids":["https://openalex.org/I3019586173","https://openalex.org/I921990950"],"apc_list":{"value":2650,"currency":"USD","value_usd":2650},"apc_paid":null,"fwci":0.774,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.78100755,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"9","issue":"4","first_page":"417","last_page":"425"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alcohol-consumption","display_name":"alcohol consumption","score":0.8629999756813049},{"id":"https://openalex.org/keywords/alpha-1-antitrypsin-deficiency","display_name":"alpha-1 antitrypsin deficiency","score":0.9430000185966492},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.9710000157356262},{"id":"https://openalex.org/keywords/emergency-department-visits","display_name":"emergency department visits","score":0.9570000171661377},{"id":"https://openalex.org/keywords/hospitalization","display_name":"hospitalization","score":0.8489999771118164},{"id":"https://openalex.org/keywords/problem-drinking","display_name":"problem drinking","score":0.9570000171661377},{"id":"https://openalex.org/keywords/cage-screening","display_name":"CAGE screening","score":0.7089999914169312},{"id":"https://openalex.org/keywords/tobacco-smoke-exposure","display_name":"tobacco smoke exposure","score":0.9179999828338623}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.856478750705719},{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.8477317094802856},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.6653062701225281},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5356708765029907},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.46273550391197205},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.4525730311870575},{"id":"https://openalex.org/C3019635848","wikidata":"https://www.wikidata.org/wiki/Q154","display_name":"Alcohol consumption","level":3,"score":0.4486690163612366},{"id":"https://openalex.org/C143095724","wikidata":"https://www.wikidata.org/wiki/Q515895","display_name":"Odds","level":3,"score":0.43903249502182007},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.4331303536891937},{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.38317662477493286},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2959177494049072},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004636","descriptor_name":"Emergency Service, Hospital","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D004636","descriptor_name":"Emergency Service, Hospital","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D004636","descriptor_name":"Emergency Service, Hospital","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006760","descriptor_name":"Hospitalization","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D006760","descriptor_name":"Hospitalization","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D006760","descriptor_name":"Hospitalization","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012959","descriptor_name":"Socioeconomic Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012959","descriptor_name":"Socioeconomic Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012959","descriptor_name":"Socioeconomic Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019896","descriptor_name":"alpha 1-Antitrypsin Deficiency","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D019896","descriptor_name":"alpha 1-Antitrypsin Deficiency","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D019896","descriptor_name":"alpha 1-Antitrypsin Deficiency","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D019973","descriptor_name":"Alcohol-Related Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D019973","descriptor_name":"Alcohol-Related Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D019973","descriptor_name":"Alcohol-Related Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D019973","descriptor_name":"Alcohol-Related Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D019973","descriptor_name":"Alcohol-Related Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D019973","descriptor_name":"Alcohol-Related Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D019973","descriptor_name":"Alcohol-Related Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D019973","descriptor_name":"Alcohol-Related Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D019973","descriptor_name":"Alcohol-Related Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3109/15412555.2012.684414","doi":"https://doi.org/10.3109/15412555.2012.684414","is_oa":true,"landing_page_url":"https://doi.org/10.3109/15412555.2012.684414","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/15412555.2012.684414?needAccess=true&role=button","source":{"id":"https://openalex.org/S15387528","display_name":"COPD Journal of Chronic Obstructive Pulmonary Disease","issn_l":"1541-2555","issn":["1541-2555","1541-2563"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","raw_type":"journal-article"},{"id":"pmid:22651849","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22651849","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"COPD","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2722057","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3603142","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3603142","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3603142","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"COPD","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3109/15412555.2012.684414","doi":"https://doi.org/10.3109/15412555.2012.684414","is_oa":true,"landing_page_url":"https://doi.org/10.3109/15412555.2012.684414","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/15412555.2012.684414?needAccess=true&role=button","source":{"id":"https://openalex.org/S15387528","display_name":"COPD Journal of Chronic Obstructive Pulmonary Disease","issn_l":"1541-2555","issn":["1541-2555","1541-2563"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8999999761581421,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1675082440","display_name":"Illness Perceptions, the Social Environment and COPD","funder_award_id":"F32HL083687","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3956756539","display_name":"The Social Environment, Psychological Distress, and Clinical Outcomes in COPD","funder_award_id":"K23HL091049","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5072840077","display_name":"Cardiopulmonary Mechanisms Affecting Cognition in COPD","funder_award_id":"K23HL095658","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7802998852","display_name":null,"funder_award_id":"K23095658","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"},{"id":"https://openalex.org/G998814062","display_name":"Colorado Clinical and Translational Science Institute (UL1)","funder_award_id":"UL1RR025780","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320306078","display_name":"U.S. Department of Defense","ror":"https://ror.org/0447fe631"},{"id":"https://openalex.org/F4320310846","display_name":"University of South Carolina","ror":"https://ror.org/02b6qw903"},{"id":"https://openalex.org/F4320313443","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139307405.pdf","grobid_xml":"https://content.openalex.org/works/W2139307405.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W125923677","https://openalex.org/W1964727784","https://openalex.org/W1977234765","https://openalex.org/W1981602900","https://openalex.org/W1983638360","https://openalex.org/W1993551530","https://openalex.org/W2004652472","https://openalex.org/W2028243322","https://openalex.org/W2032030225","https://openalex.org/W2038922251","https://openalex.org/W2039005378","https://openalex.org/W2054897163","https://openalex.org/W2066322481","https://openalex.org/W2104101154","https://openalex.org/W2115648363","https://openalex.org/W2118220271","https://openalex.org/W2134826076","https://openalex.org/W2137134542","https://openalex.org/W2147927117","https://openalex.org/W2161665411","https://openalex.org/W2162363996","https://openalex.org/W2165361259","https://openalex.org/W2166191793","https://openalex.org/W2166281097","https://openalex.org/W2916511598","https://openalex.org/W2917600742","https://openalex.org/W4232549932","https://openalex.org/W4254121089","https://openalex.org/W4255552701"],"related_works":["https://openalex.org/W2314332699","https://openalex.org/W2915430768","https://openalex.org/W2137134542","https://openalex.org/W4387253901","https://openalex.org/W4299515265","https://openalex.org/W7160512634","https://openalex.org/W4387981531","https://openalex.org/W2962575324","https://openalex.org/W2121577869","https://openalex.org/W3091315761"],"abstract_inverted_index":{"Excessive":[0],"alcohol":[1,16,51,62,73,156,238],"use":[2,17,63,239,249],"in":[3,18,105,139,169,181,240],"COPD":[4,28,104,168],"has":[5],"been":[6],"associated":[7,79,146],"with":[8,26,80,147,186,203],"increased":[9],"mortality;":[10],"however,":[11],"little":[12],"is":[13],"known":[14],"about":[15,50],"AATD-associated":[19,27],"COPD.":[20,60],"A":[21],"total":[22],"of":[23,39,97,122,128,162,222,228,250],"538":[24],"individuals":[25,176,185,202,245],"completed":[29,36],"questionnaires":[30],"at":[31,90,246],"baseline":[32,91,118],"and":[33,43,57,71,76,100,117,134,150,201],"330":[34],"also":[35],"2":[37],"years":[38,109],"follow-up":[40],"questionnaires.":[41],"Demographic":[42,75],"health":[44,119,253],"information":[45,49],"was":[46,64,92,145,158],"collected,":[47],"including":[48],"use,":[52],"ER":[53,98,165,224],"visits":[54,99],"for":[55,59,103,114,167,235,248],"COPD,":[56],"hospitalizations":[58],"Problem":[61,88,143],"characterized":[65],"using":[66,85,110],"the":[67,106,123,132,140,170,182],"CAGE":[68,133],"screening":[69],"questionnaire":[70],"recent":[72,236],"consumption.":[74],"clinical":[77],"characteristics":[78],"problem":[81,129,137,179,229],"drinking":[82,89,130,138,144,180,230],"were":[83],"identified":[84],"logistic":[86,111],"regression.":[87],"examined":[93],"as":[94],"a":[95,126,159],"predictor":[96,161],"hospital":[101,232],"admissions":[102],"subsequent":[107,171],"two":[108,172],"regression":[112],"adjusting":[113],"demographic":[115],"variables":[116],"status.":[120],"14%":[121],"sample":[124],"reported":[125,136,178],"history":[127],"per":[131],"8%":[135],"past":[141,183],"week.":[142],"higher":[148],"education":[149],"greater":[151],"lifetime":[152],"tobacco":[153],"exposure.":[154],"Recent":[155],"consumption":[157,188,205],"significant":[160],"having":[163],"an":[164,223],"visit":[166],"years.":[173],"Compared":[174],"to":[175,196,213],"who":[177],"week,":[184],"no":[187],"(OR":[189,206],"=":[190,194,199,207,211,216],"0.32,":[191],"95%":[192,209],"CI":[193,210],"0.10":[195],"0.97,":[197],"p":[198,215],".043)":[200],"low-to-moderate":[204],"0.25,":[208],"0.08":[212],"0.77,":[214],".016)":[217],"had":[218],"significantly":[219],"lower":[220],"odds":[221],"visit.":[225],"Neither":[226],"measure":[227],"predicted":[231],"admission.":[233],"Screening":[234],"excessive":[237],"this":[241],"population":[242],"may":[243],"identify":[244],"risk":[247],"costly":[251],"emergency":[252],"services.":[254]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}