{"id":"https://openalex.org/W2139288789","doi":"https://doi.org/10.1002/jbm.b.33239","title":"SrO\u2010 and MgO\u2010doped microwave sintered 3D printed tricalcium phosphate scaffolds: Mechanical properties and in vivo osteogenesis in a rabbit model","display_name":"SrO\u2010 and MgO\u2010doped microwave sintered 3D printed tricalcium phosphate scaffolds: Mechanical properties and in vivo osteogenesis in a rabbit model","publication_year":2014,"publication_date":"2014-07-08","ids":{"openalex":"https://openalex.org/W2139288789","doi":"https://doi.org/10.1002/jbm.b.33239","mag":"2139288789","pmid":"https://pubmed.ncbi.nlm.nih.gov/25045131"},"language":"en","primary_location":{"id":"doi:10.1002/jbm.b.33239","doi":"https://doi.org/10.1002/jbm.b.33239","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jbm.b.33239","pdf_url":null,"source":{"id":"https://openalex.org/S198061209","display_name":"Journal of Biomedical Materials Research Part B Applied Biomaterials","issn_l":"1552-4973","issn":["1552-4973","1552-4981"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Materials Research Part B: Applied Biomaterials","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083382489","display_name":"Solaiman Tarafder","orcid":"https://orcid.org/0000-0001-9659-690X","observed_orcids":["https://orcid.org/0000-0001-9659-690X"]},"institutions":[{"id":"https://openalex.org/I72951846","display_name":"Washington State University","ror":"https://ror.org/05dk0ce17","country_code":"US","type":"education","lineage":["https://openalex.org/I72951846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Solaiman Tarafder","raw_affiliation_strings":["W.M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University Pullman Washington 99164"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"W.M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University Pullman Washington 99164","institution_ids":["https://openalex.org/I72951846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114045699","display_name":"William S. Dernell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72951846","display_name":"Washington State University","ror":"https://ror.org/05dk0ce17","country_code":"US","type":"education","lineage":["https://openalex.org/I72951846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William S. Dernell","raw_affiliation_strings":["Department of Veterinary Clinical Sciences College of Veterinary Medicine, Washington State University Pullman Washington 99164"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Clinical Sciences College of Veterinary Medicine, Washington State University Pullman Washington 99164","institution_ids":["https://openalex.org/I72951846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000075961","display_name":"Amit Kumar Bandyopadhyay","orcid":"https://orcid.org/0000-0003-0992-5387","observed_orcids":["https://orcid.org/0000-0003-0992-5387"]},"institutions":[{"id":"https://openalex.org/I72951846","display_name":"Washington State University","ror":"https://ror.org/05dk0ce17","country_code":"US","type":"education","lineage":["https://openalex.org/I72951846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amit Bandyopadhyay","raw_affiliation_strings":["W.M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University Pullman Washington 99164"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"W.M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University Pullman Washington 99164","institution_ids":["https://openalex.org/I72951846"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025156200","display_name":"Susmita Bose","orcid":"https://orcid.org/0000-0001-8601-016X","observed_orcids":["https://orcid.org/0000-0001-8601-016X"]},"institutions":[{"id":"https://openalex.org/I72951846","display_name":"Washington State University","ror":"https://ror.org/05dk0ce17","country_code":"US","type":"education","lineage":["https://openalex.org/I72951846"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Susmita Bose","raw_affiliation_strings":["W.M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University Pullman Washington 99164"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"W.M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University Pullman Washington 99164","institution_ids":["https://openalex.org/I72951846"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5025156200"],"corresponding_institution_ids":["https://openalex.org/I72951846"],"apc_list":{"value":3400,"currency":"USD","value_usd":3400},"apc_paid":null,"fwci":5.3721,"has_fulltext":false,"cited_by_count":124,"citation_normalized_percentile":{"value":0.96487325,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"103","issue":"3","first_page":"679","last_page":"690"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10783","display_name":"Additive Manufacturing and 3D Printing Technologies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2203","display_name":"Automotive Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tricalcium-phosphate","display_name":"tricalcium phosphate","score":0.9210000038146973},{"id":"https://openalex.org/keywords/microwave-sintering","display_name":"microwave sintering","score":0.9070000052452087},{"id":"https://openalex.org/keywords/mgo-doping","display_name":"MgO doping","score":1.0},{"id":"https://openalex.org/keywords/3d-printed-scaffolds","display_name":"3D-printed scaffolds","score":0.8799999952316284},{"id":"https://openalex.org/keywords/porous-scaffolds","display_name":"porous scaffolds","score":0.6510000228881836},{"id":"https://openalex.org/keywords/mechanical-strength","display_name":"mechanical strength","score":0.7379999756813049},{"id":"https://openalex.org/keywords/compressive-strength","display_name":"compressive strength","score":0.8360000252723694},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.8270000219345093},{"id":"https://openalex.org/keywords/vasculogenesis","display_name":"vasculogenesis","score":0.722000002861023},{"id":"https://openalex.org/keywords/bone-tissue-engineering","display_name":"bone tissue engineering","score":0.6019999980926514},{"id":"https://openalex.org/keywords/osteocalcin","display_name":"osteocalcin","score":0.7379999756813049},{"id":"https://openalex.org/keywords/multiscale-porosity","display_name":"multiscale porosity","score":0.7139999866485596},{"id":"https://openalex.org/keywords/guided-tissue-regeneration","display_name":"guided tissue regeneration","score":0.7490000128746033}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.8161336183547974},{"id":"https://openalex.org/C30407753","wikidata":"https://www.wikidata.org/wiki/Q186191","display_name":"Compressive strength","level":2,"score":0.6062840223312378},{"id":"https://openalex.org/C6648577","wikidata":"https://www.wikidata.org/wiki/Q622669","display_name":"Porosity","level":2,"score":0.5481987595558167},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5455174446105957},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.48535361886024475},{"id":"https://openalex.org/C2781201070","wikidata":"https://www.wikidata.org/wiki/Q2790033","display_name":"Bioceramic","level":2,"score":0.4717073142528534},{"id":"https://openalex.org/C2777581544","wikidata":"https://www.wikidata.org/wiki/Q844613","display_name":"Sintering","level":2,"score":0.45019036531448364},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4498719573020935},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.43888455629348755},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001861","descriptor_name":"Bone Regeneration","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002130","descriptor_name":"Calcium Phosphates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002130","descriptor_name":"Calcium Phosphates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005269","descriptor_name":"Femur","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005269","descriptor_name":"Femur","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D008277","descriptor_name":"Magnesium Oxide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008422","descriptor_name":"Materials Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008872","descriptor_name":"Microwaves","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010012","descriptor_name":"Osteogenesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D010087","descriptor_name":"Oxides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013324","descriptor_name":"Strontium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015675","descriptor_name":"Osteocalcin","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D016062","descriptor_name":"Porosity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018786","descriptor_name":"Bone Substitutes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019245","descriptor_name":"Compressive Strength","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D066330","descriptor_name":"Printing, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/jbm.b.33239","doi":"https://doi.org/10.1002/jbm.b.33239","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jbm.b.33239","pdf_url":null,"source":{"id":"https://openalex.org/S198061209","display_name":"Journal of Biomedical Materials Research Part B Applied Biomaterials","issn_l":"1552-4973","issn":["1552-4973","1552-4981"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Materials Research Part B: Applied Biomaterials","raw_type":"journal-article"},{"id":"pmid:25045131","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25045131","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomedical materials research. Part B, Applied biomaterials","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.428600013256073,"display_name":"Industry, innovation and infrastructure","id":"https://metadata.un.org/sdg/9"},{"score":0.4043000042438507,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3005733191","display_name":null,"funder_award_id":"R01-EB007351","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G6944855786","display_name":"Resorbable Calcium Phosphate Ceramics for Bone Graft.","funder_award_id":"5r01eb007351-04","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000132615","display_name":null,"funder_award_id":"NIH-R01-EB-007351","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320309913","display_name":"Washington State University","ror":"https://ror.org/05dk0ce17"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1564257292","https://openalex.org/W1965296596","https://openalex.org/W1965676278","https://openalex.org/W1967214968","https://openalex.org/W1968984661","https://openalex.org/W1973040053","https://openalex.org/W1980946770","https://openalex.org/W1985301413","https://openalex.org/W1987546158","https://openalex.org/W1991889839","https://openalex.org/W1997600457","https://openalex.org/W2001093535","https://openalex.org/W2005720246","https://openalex.org/W2009724683","https://openalex.org/W2014555391","https://openalex.org/W2015012905","https://openalex.org/W2016579697","https://openalex.org/W2016828760","https://openalex.org/W2018613635","https://openalex.org/W2020778747","https://openalex.org/W2021261257","https://openalex.org/W2022577997","https://openalex.org/W2023208730","https://openalex.org/W2024794055","https://openalex.org/W2032097545","https://openalex.org/W2033116434","https://openalex.org/W2041446238","https://openalex.org/W2051083411","https://openalex.org/W2051105757","https://openalex.org/W2051720322","https://openalex.org/W2058519879","https://openalex.org/W2061456601","https://openalex.org/W2071436788","https://openalex.org/W2071677160","https://openalex.org/W2077230011","https://openalex.org/W2080921228","https://openalex.org/W2081199190","https://openalex.org/W2096735953","https://openalex.org/W2103378167","https://openalex.org/W2111082877","https://openalex.org/W2115870439","https://openalex.org/W2122448541","https://openalex.org/W2147711651","https://openalex.org/W2152205487","https://openalex.org/W2159210886","https://openalex.org/W2161515689","https://openalex.org/W2165022412","https://openalex.org/W2169341720","https://openalex.org/W4300065620"],"related_works":["https://openalex.org/W1967214968","https://openalex.org/W1564257292","https://openalex.org/W2599365144","https://openalex.org/W1499298412","https://openalex.org/W2802470567","https://openalex.org/W2023208730","https://openalex.org/W2280288513","https://openalex.org/W2111082877","https://openalex.org/W2084477297","https://openalex.org/W4384562225"],"abstract_inverted_index":{"The":[0],"presence":[1,49,168],"of":[2,38,50,124,169,197],"interconnected":[3,87],"macro":[4,39,89],"pores":[5,90],"allows":[6],"guided":[7],"tissue":[8,11],"regeneration":[9],"in":[10,56,62,99,114,174,185,206],"engineering":[12],"scaffolds.":[13,44,210],"However,":[14],"highly":[15],"porous":[16,40],"scaffolds":[17,58,80,145,182,219],"suffer":[18],"from":[19],"having":[20],"poor":[21],"mechanical":[22,36,60,100],"strength.":[23],"Previously,":[24],"we":[25],"showed":[26],"that":[27,84,214],"microwave":[28,139],"sintering":[29],"could":[30],"successfully":[31],"be":[32],"used":[33,68],"to":[34,109],"improve":[35],"strength":[37],"tricalcium":[41],"phosphate":[42],"(TCP)":[43],"This":[45],"study":[46],"reports":[47],"the":[48,167,207,221],"SrO":[51,110,170],"and":[52,61,104,111,129,138,152,161,171,193,201,230],"MgO":[53,112,172],"as":[54,116,177],"dopants":[55,173],"TCP":[57,115,176,181,209,218],"improves":[59],"vivo":[63],"biological":[64],"performance.":[65],"We":[66],"have":[67,220],"direct":[69],"three":[70],"dimensional":[71],"printing":[72],"(3DP)":[73],"technology":[74],"for":[75,142,223],"scaffold":[76],"fabrication.":[77],"These":[78],"3DP":[79,144,175,216],"possessed":[81],"multiscale":[82],"porosity,":[83],"is,":[85],"3D":[86],"designed":[88,149],"along":[91],"with":[92,118,146,179],"intrinsic":[93],"micro":[94],"pores.":[95,150],"A":[96],"significant":[97],"increase":[98],"strength,":[101],"between":[102],"37":[103],"41%,":[105],"was":[106],"achieved":[107,135],"due":[108],"doping":[113],"compared":[117,178],"pure":[119,180],"TCP.":[120],"Maximum":[121],"compressive":[122],"strengths":[123],"9.38":[125],"\u00b1":[126,131],"1.86":[127],"MPa":[128,133],"12.01":[130],"1.56":[132],"were":[134,204],"by":[136,166],"conventional":[137],"sintering,":[140],"respectively,":[141],"SrO-MgO-doped":[143,217],"500":[147],"\u03bcm":[148],"Histomorphological":[151],"histomorphometric":[153],"analysis":[154],"revealed":[155],"a":[156],"significantly":[157],"higher":[158],"osteoid,":[159],"bone":[160],"haversian":[162],"canal":[163],"formation":[164],"induced":[165],"when":[183],"tested":[184],"rabbit":[186],"femoral":[187],"condyle":[188],"defect":[189],"model.":[190],"Increased":[191],"osteon":[192],"thus":[194],"enhanced":[195],"network":[196],"blood":[198],"vessel":[199],"formation,":[200],"osteocalcin":[202],"expression":[203],"observed":[205],"doped":[208],"Our":[211],"results":[212],"show":[213],"these":[215],"potential":[222],"early":[224],"wound":[225],"healing":[226],"through":[227],"accelerated":[228],"osteogenesis":[229],"vasculogenesis.":[231]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}