{"id":"https://openalex.org/W2139285527","doi":"https://doi.org/10.1371/journal.pone.0043837","title":"In Vivo Quantification Reveals Extensive Natural Variation in Mitochondrial Form and Function in Caenorhabditis briggsae","display_name":"In Vivo Quantification Reveals Extensive Natural Variation in Mitochondrial Form and Function in Caenorhabditis briggsae","publication_year":2012,"publication_date":"2012-08-28","ids":{"openalex":"https://openalex.org/W2139285527","doi":"https://doi.org/10.1371/journal.pone.0043837","mag":"2139285527","pmid":"https://pubmed.ncbi.nlm.nih.gov/22952781","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3429487"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0043837","doi":"https://doi.org/10.1371/journal.pone.0043837","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0043837","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043837&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043837&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022601114","display_name":"Kiley A. Hicks","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126345244","display_name":"Portland State University","ror":"https://ror.org/00yn2fy02","country_code":"US","type":"education","lineage":["https://openalex.org/I126345244"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kiley A. Hicks","raw_affiliation_strings":["Biology Department, Portland State University, Portland, Oregon, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Portland State University, Portland, Oregon, United States of America","institution_ids":["https://openalex.org/I126345244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009768579","display_name":"Dana K. Howe","orcid":"https://orcid.org/0000-0002-2131-6114","observed_orcids":["https://orcid.org/0000-0002-2131-6114"]},"institutions":[{"id":"https://openalex.org/I131249849","display_name":"Oregon State University","ror":"https://ror.org/00ysfqy60","country_code":"US","type":"education","lineage":["https://openalex.org/I131249849"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dana K. Howe","raw_affiliation_strings":["Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America","institution_ids":["https://openalex.org/I131249849"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049245009","display_name":"Aubrey Leung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131249849","display_name":"Oregon State University","ror":"https://ror.org/00ysfqy60","country_code":"US","type":"education","lineage":["https://openalex.org/I131249849"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aubrey Leung","raw_affiliation_strings":["Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America","institution_ids":["https://openalex.org/I131249849"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044877632","display_name":"Dee R. Denver","orcid":"https://orcid.org/0000-0002-6324-063X","observed_orcids":["https://orcid.org/0000-0002-6324-063X"]},"institutions":[{"id":"https://openalex.org/I131249849","display_name":"Oregon State University","ror":"https://ror.org/00ysfqy60","country_code":"US","type":"education","lineage":["https://openalex.org/I131249849"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dee R. Denver","raw_affiliation_strings":["Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America","institution_ids":["https://openalex.org/I131249849"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065030704","display_name":"Suzanne Estes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126345244","display_name":"Portland State University","ror":"https://ror.org/00yn2fy02","country_code":"US","type":"education","lineage":["https://openalex.org/I126345244"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Suzanne Estes","raw_affiliation_strings":["Biology Department, Portland State University, Portland, Oregon, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Portland State University, Portland, Oregon, United States of America","institution_ids":["https://openalex.org/I126345244"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5065030704"],"corresponding_institution_ids":["https://openalex.org/I126345244"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":1.5412,"has_fulltext":true,"cited_by_count":35,"citation_normalized_percentile":{"value":0.82143425,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"7","issue":"8","first_page":"e43837","last_page":"e43837"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.7896000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.7896000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.05950000137090683,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11056","display_name":"Physiological and biochemical adaptations","score":0.04360000044107437,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/caenorhabditis-briggsae","display_name":"Caenorhabditis briggsae","score":0.9549999833106995},{"id":"https://openalex.org/keywords/mitochondrial-heteroplasmy","display_name":"mitochondrial heteroplasmy","score":0.8640000224113464},{"id":"https://openalex.org/keywords/mitochondrial-membrane-potential","display_name":"mitochondrial membrane potential","score":0.7950000166893005},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9940000176429749},{"id":"https://openalex.org/keywords/mitochondrial-morphology","display_name":"mitochondrial morphology","score":0.8690000176429749},{"id":"https://openalex.org/keywords/natural-variability","display_name":"natural variation","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8815971612930298},{"id":"https://openalex.org/C181561989","wikidata":"https://www.wikidata.org/wiki/Q2581905","display_name":"Heteroplasmy","level":4,"score":0.7890437841415405},{"id":"https://openalex.org/C24586158","wikidata":"https://www.wikidata.org/wiki/Q27075","display_name":"Mitochondrial DNA","level":3,"score":0.7727510929107666},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5542282462120056},{"id":"https://openalex.org/C2776496032","wikidata":"https://www.wikidata.org/wiki/Q1904768","display_name":"Caenorhabditis","level":4,"score":0.5102970600128174},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.48477548360824585},{"id":"https://openalex.org/C2778944004","wikidata":"https://www.wikidata.org/wiki/Q91703","display_name":"Caenorhabditis elegans","level":3,"score":0.46966326236724854},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.42417019605636597},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.4105607867240906},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4104043245315552},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3490818738937378}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002107","descriptor_name":"Caenorhabditis","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D002107","descriptor_name":"Caenorhabditis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002107","descriptor_name":"Caenorhabditis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004272","descriptor_name":"DNA, Mitochondrial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006824","descriptor_name":"Hybridization, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045222","descriptor_name":"Electron Transport Chain Complex Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053078","descriptor_name":"Membrane Potential, Mitochondrial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pone.0043837","doi":"https://doi.org/10.1371/journal.pone.0043837","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0043837","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043837&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3429487","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3429487","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:22952781","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22952781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pdxscholar.library.pdx.edu:bio_fac-1011","doi":null,"is_oa":true,"landing_page_url":"https://pdxscholar.library.pdx.edu/bio_fac/12","pdf_url":null,"source":{"id":"https://openalex.org/S4377196300","display_name":"PDXScholar  (Portland State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I126345244","host_organization_name":"Portland State University","host_organization_lineage":["https://openalex.org/I126345244"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biology Faculty Publications and Presentations","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:b988391bec5a45a08e17818c8f3edcd4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b988391bec5a45a08e17818c8f3edcd4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 7, Iss 8, p e43837 (2012)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/120783","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/_In_Vivo_Quantification_Reveals_Extensive_Natural_Variation_in_Mitochondrial_Form_and_Function_in_Caenorhabditis_briggsae_/120783","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0043837","doi":"https://doi.org/10.1371/journal.pone.0043837","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0043837","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043837&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5778256443","display_name":"Mutational and evolutionary impact of mitochondrial dysfunction","funder_award_id":"R01GM087628","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139285527.pdf","grobid_xml":"https://content.openalex.org/works/W2139285527.grobid-xml"},"referenced_works_count":99,"referenced_works":["https://openalex.org/W1495825745","https://openalex.org/W1500849516","https://openalex.org/W1504597729","https://openalex.org/W1604984248","https://openalex.org/W1825823071","https://openalex.org/W1963795151","https://openalex.org/W1965701630","https://openalex.org/W1967672708","https://openalex.org/W1976139454","https://openalex.org/W1977332628","https://openalex.org/W1979048203","https://openalex.org/W1979633540","https://openalex.org/W1979705609","https://openalex.org/W1983066766","https://openalex.org/W1983879895","https://openalex.org/W1994362240","https://openalex.org/W1996234796","https://openalex.org/W1997360166","https://openalex.org/W1997422422","https://openalex.org/W2010094123","https://openalex.org/W2010431679","https://openalex.org/W2012264972","https://openalex.org/W2012373720","https://openalex.org/W2015638974","https://openalex.org/W2021750095","https://openalex.org/W2023542615","https://openalex.org/W2024595059","https://openalex.org/W2026509565","https://openalex.org/W2026960323","https://openalex.org/W2030145039","https://openalex.org/W2034431038","https://openalex.org/W2036596850","https://openalex.org/W2037243381","https://openalex.org/W2037855135","https://openalex.org/W2037951418","https://openalex.org/W2038323003","https://openalex.org/W2039093830","https://openalex.org/W2041835091","https://openalex.org/W2043829591","https://openalex.org/W2044494908","https://openalex.org/W2044747701","https://openalex.org/W2063382649","https://openalex.org/W2067410194","https://openalex.org/W2072261604","https://openalex.org/W2073579049","https://openalex.org/W2078139350","https://openalex.org/W2079659465","https://openalex.org/W2082882491","https://openalex.org/W2083720450","https://openalex.org/W2083899719","https://openalex.org/W2084621494","https://openalex.org/W2085396235","https://openalex.org/W2086576625","https://openalex.org/W2086576678","https://openalex.org/W2090738704","https://openalex.org/W2092309784","https://openalex.org/W2093988460","https://openalex.org/W2094421676","https://openalex.org/W2095374280","https://openalex.org/W2097239618","https://openalex.org/W2100659636","https://openalex.org/W2104952200","https://openalex.org/W2105144460","https://openalex.org/W2108049416","https://openalex.org/W2121503267","https://openalex.org/W2121966499","https://openalex.org/W2122341467","https://openalex.org/W2123004132","https://openalex.org/W2126624770","https://openalex.org/W2130497877","https://openalex.org/W2130995821","https://openalex.org/W2131768903","https://openalex.org/W2132579877","https://openalex.org/W2133331872","https://openalex.org/W2134891434","https://openalex.org/W2135588013","https://openalex.org/W2136046510","https://openalex.org/W2136937485","https://openalex.org/W2141201649","https://openalex.org/W2141901922","https://openalex.org/W2145882912","https://openalex.org/W2149120324","https://openalex.org/W2151698573","https://openalex.org/W2152363514","https://openalex.org/W2155265427","https://openalex.org/W2157299674","https://openalex.org/W2159357690","https://openalex.org/W2165198127","https://openalex.org/W2171215342","https://openalex.org/W2171810396","https://openalex.org/W2176275556","https://openalex.org/W2187370199","https://openalex.org/W2963623381","https://openalex.org/W3147604473","https://openalex.org/W4241099912","https://openalex.org/W4241398143","https://openalex.org/W4244693581","https://openalex.org/W4300198507","https://openalex.org/W4308665337"],"related_works":["https://openalex.org/W7098616096","https://openalex.org/W30793014","https://openalex.org/W1816693178","https://openalex.org/W2049744591","https://openalex.org/W3000304977","https://openalex.org/W1968971029","https://openalex.org/W2930087886","https://openalex.org/W2105144460","https://openalex.org/W318876637","https://openalex.org/W2057845006"],"abstract_inverted_index":{"We":[0,40,106],"have":[1],"analyzed":[2],"natural":[3,140,155],"variation":[4,23,65,84,136,156],"in":[5,24,42,66,110,120,157],"mitochondrial":[6,20,47,71,96,141],"form":[7,26],"and":[8,56,61,133,160,167],"function":[9],"among":[10],"a":[11,28],"set":[12],"of":[13,27,45,58,80,103,112,124,139,153,164],"Caenorhabditis":[14],"briggsae":[15],"isolates":[16],"known":[17],"to":[18,118],"harbor":[19],"DNA":[21],"structural":[22],"the":[25,81,162],"heteroplasmic":[29],"nad5":[30],"gene":[31],"deletion":[32],"(nad5\u0394)":[33],"that":[34,147],"correlates":[35],"negatively":[36],"with":[37,76],"organismal":[38],"fitness.":[39],"performed":[41],"vivo":[43],"quantification":[44],"24":[46],"phenotypes":[48,72,159],"including":[49],"reactive":[50],"oxygen":[51],"species":[52,150],"level,":[53],"membrane":[54,97],"potential,":[55],"aspects":[57],"organelle":[59],"morphology,":[60],"observed":[62],"significant":[63],"among-isolate":[64,82],"18":[67],"traits.":[68],"Although":[69],"several":[70],"were":[73],"non-linearly":[74],"associated":[75],"nad5\u0394":[77],"levels,":[78],"most":[79],"phenotypic":[83],"could":[85],"be":[86],"accounted":[87],"for":[88,115,130],"by":[89],"phylogeographic":[90],"clade":[91,104],"membership.":[92,105],"In":[93],"particular,":[94],"isolate-specific":[95],"potential":[98,163],"was":[99],"an":[100],"excellent":[101],"predictor":[102],"interpret":[107],"this":[108],"result":[109],"light":[111],"recent":[113],"evidence":[114],"local":[116],"adaptation":[117],"temperature":[119],"C.":[121],"briggsae.":[122],"Analysis":[123],"mitochondrial-nuclear":[125],"hybrid":[126],"strains":[127],"provided":[128],"support":[129],"both":[131],"mtDNA":[132],"nuclear":[134],"genetic":[135],"as":[137],"drivers":[138],"phenotype":[142],"variation.":[143],"This":[144],"study":[145],"demonstrates":[146],"multicellular":[148],"eukaryotic":[149],"are":[151],"capable":[152],"extensive":[154],"organellar":[158],"highlights":[161],"integrating":[165],"evolutionary":[166],"cell":[168],"biology":[169],"perspectives.":[170]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}