{"id":"https://openalex.org/W2139281705","doi":"https://doi.org/10.1016/j.colsurfb.2009.03.005","title":"Formulation optimization and in situ absorption in rat intestinal tract of quercetin-loaded microemulsion","display_name":"Formulation optimization and in situ absorption in rat intestinal tract of quercetin-loaded microemulsion","publication_year":2009,"publication_date":"2009-03-26","ids":{"openalex":"https://openalex.org/W2139281705","doi":"https://doi.org/10.1016/j.colsurfb.2009.03.005","mag":"2139281705","pmid":"https://pubmed.ncbi.nlm.nih.gov/19375897"},"language":"en","primary_location":{"id":"doi:10.1016/j.colsurfb.2009.03.005","doi":"https://doi.org/10.1016/j.colsurfb.2009.03.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.colsurfb.2009.03.005","pdf_url":null,"source":{"id":"https://openalex.org/S22793308","display_name":"Colloids and Surfaces B Biointerfaces","issn_l":"0927-7765","issn":["0927-7765","1873-4367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Colloids and Surfaces B: Biointerfaces","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100462452","display_name":"Yan Gao","orcid":"https://orcid.org/0000-0002-3891-2617","observed_orcids":["https://orcid.org/0000-0002-3891-2617"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Gao","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044845324","display_name":"Yuqiang Wang","orcid":"https://orcid.org/0000-0002-8757-4829","observed_orcids":["https://orcid.org/0000-0002-8757-4829"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuqiang Wang","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101578128","display_name":"Yukun Ma","orcid":"https://orcid.org/0000-0003-1890-9776","observed_orcids":["https://orcid.org/0000-0003-1890-9776"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yukun Ma","raw_affiliation_strings":["Department of Pharmacy, The Second People's Hospital of Jinan, Jinan 250001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, The Second People's Hospital of Jinan, Jinan 250001, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101101847","display_name":"Aihua Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Aihua Yu","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108873504","display_name":"Fu-Hong Cai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fengqun Cai","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wei Shao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Shao","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062886652","display_name":"Guangxi Zhai","orcid":"https://orcid.org/0000-0003-3860-948X","observed_orcids":["https://orcid.org/0000-0003-3860-948X","https://orcid.org/0000-0001-5851-1311","https://orcid.org/0000-0003-2678-9129","https://orcid.org/0000-0003-3469-7603"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guangxi Zhai","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China","institution_ids":["https://openalex.org/I154099455"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062886652"],"corresponding_institution_ids":["https://openalex.org/I154099455"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":null,"fwci":4.6579,"has_fulltext":false,"cited_by_count":146,"citation_normalized_percentile":{"value":0.95642458,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"71","issue":"2","first_page":"306","last_page":"314"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.00559999980032444,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/quercetin","display_name":"quercetin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/microemulsions","display_name":"microemulsions","score":0.9819999933242798},{"id":"https://openalex.org/keywords/oral-absorption","display_name":"oral absorption","score":0.6899999976158142},{"id":"https://openalex.org/keywords/poorly-water-soluble-drugs","display_name":"poorly water-soluble drugs","score":0.9309999942779541},{"id":"https://openalex.org/keywords/solubility-enhancement","display_name":"solubility enhancement","score":0.847000002861023},{"id":"https://openalex.org/keywords/in-situ-absorption","display_name":"in situ absorption","score":0.6759999990463257},{"id":"https://openalex.org/keywords/intestinal-permeability","display_name":"intestinal permeability","score":0.8169999718666077},{"id":"https://openalex.org/keywords/surfactants","display_name":"surfactants","score":0.593999981880188},{"id":"https://openalex.org/keywords/co-surfactants","display_name":"cosurfactants","score":0.9959999918937683},{"id":"https://openalex.org/keywords/droplet-size","display_name":"droplet size","score":0.7459999918937683},{"id":"https://openalex.org/keywords/micelles","display_name":"micelles","score":0.574999988079071},{"id":"https://openalex.org/keywords/rat-intestine","display_name":"rat intestine","score":0.5720000267028809}],"concepts":[{"id":"https://openalex.org/C190119865","wikidata":"https://www.wikidata.org/wiki/Q338019","display_name":"Microemulsion","level":3,"score":0.9674193859100342},{"id":"https://openalex.org/C155574463","wikidata":"https://www.wikidata.org/wiki/Q170731","display_name":"Solubility","level":2,"score":0.7103175520896912},{"id":"https://openalex.org/C2781263971","wikidata":"https://www.wikidata.org/wiki/Q409478","display_name":"Quercetin","level":3,"score":0.6812785863876343},{"id":"https://openalex.org/C125287762","wikidata":"https://www.wikidata.org/wiki/Q1758948","display_name":"Absorption (acoustics)","level":2,"score":0.6179249882698059},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6116093993186951},{"id":"https://openalex.org/C58226133","wikidata":"https://www.wikidata.org/wiki/Q1324199","display_name":"Pulmonary surfactant","level":2,"score":0.5829538702964783},{"id":"https://openalex.org/C11268172","wikidata":"https://www.wikidata.org/wiki/Q421110","display_name":"Micelle","level":3,"score":0.5675857663154602},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5509275794029236},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.38850587606430054},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.321059912443161},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.2605261206626892},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.15928763151168823},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12703844904899597},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002626","descriptor_name":"Chemistry, Pharmaceutical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004655","descriptor_name":"Emulsions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007408","descriptor_name":"Intestinal Absorption","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008823","descriptor_name":"Micelles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010477","descriptor_name":"Perfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011794","descriptor_name":"Quercetin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D011794","descriptor_name":"Quercetin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011794","descriptor_name":"Quercetin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012995","descriptor_name":"Solubility","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012996","descriptor_name":"Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046529","descriptor_name":"Microscopy, Electron, Transmission","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.colsurfb.2009.03.005","doi":"https://doi.org/10.1016/j.colsurfb.2009.03.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.colsurfb.2009.03.005","pdf_url":null,"source":{"id":"https://openalex.org/S22793308","display_name":"Colloids and Surfaces B Biointerfaces","issn_l":"0927-7765","issn":["0927-7765","1873-4367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Colloids and Surfaces B: Biointerfaces","raw_type":"journal-article"},{"id":"pmid:19375897","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19375897","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Colloids and surfaces. B, Biointerfaces","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W5737657","https://openalex.org/W91604478","https://openalex.org/W261061428","https://openalex.org/W294604442","https://openalex.org/W1966700699","https://openalex.org/W1968661040","https://openalex.org/W1971120211","https://openalex.org/W1973332563","https://openalex.org/W1973435432","https://openalex.org/W1974365978","https://openalex.org/W1974428123","https://openalex.org/W1982230391","https://openalex.org/W1986638516","https://openalex.org/W1993360693","https://openalex.org/W1994396440","https://openalex.org/W1995146295","https://openalex.org/W2000817422","https://openalex.org/W2004777338","https://openalex.org/W2010807769","https://openalex.org/W2023957632","https://openalex.org/W2024508489","https://openalex.org/W2026309482","https://openalex.org/W2030362679","https://openalex.org/W2035306529","https://openalex.org/W2038299379","https://openalex.org/W2039912507","https://openalex.org/W2043888893","https://openalex.org/W2050005850","https://openalex.org/W2052367899","https://openalex.org/W2057220775","https://openalex.org/W2061158041","https://openalex.org/W2063108311","https://openalex.org/W2063209823","https://openalex.org/W2063381770","https://openalex.org/W2071359748","https://openalex.org/W2082081389","https://openalex.org/W2088342198","https://openalex.org/W2094977785","https://openalex.org/W2102126716","https://openalex.org/W2115897413","https://openalex.org/W2117753715","https://openalex.org/W2120977461","https://openalex.org/W2152244549","https://openalex.org/W2152559989","https://openalex.org/W2156035049","https://openalex.org/W2159713677","https://openalex.org/W2362546497"],"related_works":["https://openalex.org/W7127043212","https://openalex.org/W2555099762","https://openalex.org/W2388354131","https://openalex.org/W2327117794","https://openalex.org/W2362847660","https://openalex.org/W2152006433","https://openalex.org/W1459697132","https://openalex.org/W2063381770","https://openalex.org/W2784131472","https://openalex.org/W2027368401"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}