{"id":"https://openalex.org/W2139204931","doi":"https://doi.org/10.1186/gb-2011-12-7-r64","title":"Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis","display_name":"Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis","publication_year":2011,"publication_date":"2011-07-18","ids":{"openalex":"https://openalex.org/W2139204931","doi":"https://doi.org/10.1186/gb-2011-12-7-r64","mag":"2139204931","pmid":"https://pubmed.ncbi.nlm.nih.gov/21767385","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3218826"},"language":"en","primary_location":{"id":"doi:10.1186/gb-2011-12-7-r64","doi":"https://doi.org/10.1186/gb-2011-12-7-r64","is_oa":true,"landing_page_url":"https://doi.org/10.1186/gb-2011-12-7-r64","pdf_url":"https://genomebiology.biomedcentral.com/counter/pdf/10.1186/gb-2011-12-7-r64","source":{"id":"https://openalex.org/S81160022","display_name":"Genome biology","issn_l":"1465-6906","issn":["1465-6906","1465-6914","1474-7596","1474-760X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Biology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2139204931"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://genomebiology.biomedcentral.com/counter/pdf/10.1186/gb-2011-12-7-r64","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046692579","display_name":"Laure\u2010Emmanuelle Zaragosi","orcid":"https://orcid.org/0000-0001-6747-7928","observed_orcids":["https://orcid.org/0000-0001-6747-7928"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210160500","display_name":"Institut de Pharmacologie Mol\u00e9culaire et Cellulaire","ror":"https://ror.org/05k4ema52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I201841394","https://openalex.org/I4210096427","https://openalex.org/I4210160500"]},{"id":"https://openalex.org/I4387154757","display_name":"Universit\u00e9 Nice Sophia Antipolis","ror":"https://ror.org/02k9vew78","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394","https://openalex.org/I4387154757"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laure-Emmanuelle Zaragosi","raw_affiliation_strings":["Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, 660 Route des Lucioles, Valbonne Sophia-Antipolis 06560, France","Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, Valbonne Sophia-Antipolis, France","University of Nice Sophia-Antipolis, Nice Cedex 2, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, 660 Route des Lucioles, Valbonne Sophia-Antipolis 06560, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500"]},{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, Valbonne Sophia-Antipolis, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, Nice Cedex 2, France","institution_ids":["https://openalex.org/I4387154757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016834843","display_name":"Brigitte Wdziekonski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4387154757","display_name":"Universit\u00e9 Nice Sophia Antipolis","ror":"https://ror.org/02k9vew78","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394","https://openalex.org/I4387154757"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Brigitte Wdziekonski","raw_affiliation_strings":["Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, 28 avenue de Valombrose, Nice cedex 2, 06107, France","University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, Nice cedex 2, France","University of Nice Sophia-Antipolis, Nice Cedex 2, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, 28 avenue de Valombrose, Nice cedex 2, 06107, France","institution_ids":["https://openalex.org/I1294671590"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","institution_ids":["https://openalex.org/I4387154757"]},{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, Nice cedex 2, France","institution_ids":["https://openalex.org/I1294671590"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, Nice Cedex 2, France","institution_ids":["https://openalex.org/I4387154757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022811994","display_name":"K\u00e9vin Lebrigand","orcid":"https://orcid.org/0000-0001-5604-7893","observed_orcids":["https://orcid.org/0000-0001-5604-7893"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210160500","display_name":"Institut de Pharmacologie Mol\u00e9culaire et Cellulaire","ror":"https://ror.org/05k4ema52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I201841394","https://openalex.org/I4210096427","https://openalex.org/I4210160500"]},{"id":"https://openalex.org/I4387154757","display_name":"Universit\u00e9 Nice Sophia Antipolis","ror":"https://ror.org/02k9vew78","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394","https://openalex.org/I4387154757"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Kevin Le Brigand","raw_affiliation_strings":["Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, 660 route des lucioles, Valbonne Sophia-Antipolis, 06560, France","University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, Valbonne Sophia-Antipolis, France","University of Nice Sophia-Antipolis, Nice Cedex 2, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, 660 route des lucioles, Valbonne Sophia-Antipolis, 06560, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","institution_ids":["https://openalex.org/I4387154757"]},{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, Valbonne Sophia-Antipolis, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, Nice Cedex 2, France","institution_ids":["https://openalex.org/I4387154757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036600652","display_name":"Phi Villageois","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4387154757","display_name":"Universit\u00e9 Nice Sophia Antipolis","ror":"https://ror.org/02k9vew78","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394","https://openalex.org/I4387154757"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Phi Villageois","raw_affiliation_strings":["Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, 28 avenue de Valombrose, Nice cedex 2, 06107, France","University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, Nice cedex 2, France","University of Nice Sophia-Antipolis, Nice Cedex 2, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, 28 avenue de Valombrose, Nice cedex 2, 06107, France","institution_ids":["https://openalex.org/I1294671590"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","institution_ids":["https://openalex.org/I4387154757"]},{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, Nice cedex 2, France","institution_ids":["https://openalex.org/I1294671590"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, Nice Cedex 2, France","institution_ids":["https://openalex.org/I4387154757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019765162","display_name":"Bernard P. Mari","orcid":"https://orcid.org/0000-0002-0422-9182","observed_orcids":["https://orcid.org/0000-0002-0422-9182","https://orcid.org/0000-0001-6011-4868"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210160500","display_name":"Institut de Pharmacologie Mol\u00e9culaire et Cellulaire","ror":"https://ror.org/05k4ema52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I201841394","https://openalex.org/I4210096427","https://openalex.org/I4210160500"]},{"id":"https://openalex.org/I4387154757","display_name":"Universit\u00e9 Nice Sophia Antipolis","ror":"https://ror.org/02k9vew78","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394","https://openalex.org/I4387154757"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bernard Mari","raw_affiliation_strings":["Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, 660 route des lucioles, Valbonne Sophia-Antipolis, 06560, France","University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, Valbonne Sophia-Antipolis, France","University of Nice Sophia-Antipolis, Nice Cedex 2, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, 660 route des lucioles, Valbonne Sophia-Antipolis, 06560, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","institution_ids":["https://openalex.org/I4387154757"]},{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, Valbonne Sophia-Antipolis, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, Nice Cedex 2, France","institution_ids":["https://openalex.org/I4387154757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046273802","display_name":"Rainer Waldmann","orcid":"https://orcid.org/0000-0002-4599-2926","observed_orcids":["https://orcid.org/0000-0002-4599-2926"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210160500","display_name":"Institut de Pharmacologie Mol\u00e9culaire et Cellulaire","ror":"https://ror.org/05k4ema52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I201841394","https://openalex.org/I4210096427","https://openalex.org/I4210160500"]},{"id":"https://openalex.org/I4387154757","display_name":"Universit\u00e9 Nice Sophia Antipolis","ror":"https://ror.org/02k9vew78","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394","https://openalex.org/I4387154757"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Rainer Waldmann","raw_affiliation_strings":["Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, 660 route des lucioles, Valbonne Sophia-Antipolis, 06560, France","University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, Valbonne Sophia-Antipolis, France","University of Nice Sophia-Antipolis, Nice Cedex 2, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, 660 route des lucioles, Valbonne Sophia-Antipolis, 06560, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","institution_ids":["https://openalex.org/I4387154757"]},{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, Valbonne Sophia-Antipolis, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, Nice Cedex 2, France","institution_ids":["https://openalex.org/I4387154757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084915485","display_name":"Christian Dani","orcid":"https://orcid.org/0000-0003-3228-0230","observed_orcids":["https://orcid.org/0000-0003-3228-0230"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4387154757","display_name":"Universit\u00e9 Nice Sophia Antipolis","ror":"https://ror.org/02k9vew78","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394","https://openalex.org/I4387154757"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christian Dani","raw_affiliation_strings":["Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, 28 avenue de Valombrose, Nice cedex 2, 06107, France","University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, Nice cedex 2, France","University of Nice Sophia-Antipolis, Nice Cedex 2, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, 28 avenue de Valombrose, Nice cedex 2, 06107, France","institution_ids":["https://openalex.org/I1294671590"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","institution_ids":["https://openalex.org/I4387154757"]},{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Biologie du D\u00e9veloppement et Cancer, UMR6543, Nice cedex 2, France","institution_ids":["https://openalex.org/I1294671590"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, Nice Cedex 2, France","institution_ids":["https://openalex.org/I4387154757"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044327360","display_name":"Pascal Barbry","orcid":"https://orcid.org/0000-0001-9632-6483","observed_orcids":["https://orcid.org/0000-0001-9632-6483"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210160500","display_name":"Institut de Pharmacologie Mol\u00e9culaire et Cellulaire","ror":"https://ror.org/05k4ema52","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I201841394","https://openalex.org/I4210096427","https://openalex.org/I4210160500"]},{"id":"https://openalex.org/I4387154757","display_name":"Universit\u00e9 Nice Sophia Antipolis","ror":"https://ror.org/02k9vew78","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394","https://openalex.org/I4387154757"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Pascal Barbry","raw_affiliation_strings":["Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, 660 route des lucioles, Valbonne Sophia-Antipolis, 06560, France","University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, Valbonne Sophia-Antipolis, France","University of Nice Sophia-Antipolis, Nice Cedex 2, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, 660 route des lucioles, Valbonne Sophia-Antipolis, 06560, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, 28 avenue Valrose, Nice Cedex 2, 06103, France","institution_ids":["https://openalex.org/I4387154757"]},{"raw_affiliation_string":"Centre National de la Recherche Scientifique, Institut de Pharmacologie Mol\u00e9culaire et Cellulaire, UMR-6097, Valbonne Sophia-Antipolis, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500"]},{"raw_affiliation_string":"University of Nice Sophia-Antipolis, Nice Cedex 2, France","institution_ids":["https://openalex.org/I4387154757"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5044327360"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210160500","https://openalex.org/I4387154757"],"apc_list":{"value":5490,"currency":"USD","value_usd":5490},"apc_paid":{"value":5490,"currency":"USD","value_usd":5490},"fwci":6.6799,"has_fulltext":true,"cited_by_count":237,"citation_normalized_percentile":{"value":0.97381199,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":100},"biblio":{"volume":"12","issue":"7","first_page":"R64","last_page":"R64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.5317000150680542,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.5317000150680542,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.3206000030040741,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.10580000281333923,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mir-30-family","display_name":"miR-30 family","score":0.9810000061988831},{"id":"https://openalex.org/keywords/mir-30a","display_name":"miR-30a","score":0.9760000109672546},{"id":"https://openalex.org/keywords/mir-30d","display_name":"miR-30d","score":1.0},{"id":"https://openalex.org/keywords/adipogenic-differentiation","display_name":"adipogenesis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/adipose-derived-stem-cells","display_name":"adipose-derived stem cells","score":0.9120000004768372},{"id":"https://openalex.org/keywords/runx2","display_name":"Runx2","score":0.9300000071525574},{"id":"https://openalex.org/keywords/mirna-silencing","display_name":"microRNA silencing","score":0.7929999828338623},{"id":"https://openalex.org/keywords/adipose-tissue-expansion","display_name":"adipose tissue expansion","score":0.8029999732971191},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8130000233650208},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.6489999890327454},{"id":"https://openalex.org/keywords/adipose-tissue","display_name":"adipose tissue","score":0.5440000295639038}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8592401742935181},{"id":"https://openalex.org/C122927707","wikidata":"https://www.wikidata.org/wiki/Q2824461","display_name":"Adipogenesis","level":3,"score":0.8448328971862793},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.8410316109657288},{"id":"https://openalex.org/C6929976","wikidata":"https://www.wikidata.org/wiki/Q3771881","display_name":"Regulator","level":3,"score":0.7905126214027405},{"id":"https://openalex.org/C47042493","wikidata":"https://www.wikidata.org/wiki/Q265799","display_name":"Human genetics","level":3,"score":0.5597330927848816},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5140208005905151},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.48649948835372925},{"id":"https://openalex.org/C2779341050","wikidata":"https://www.wikidata.org/wiki/Q24287527","display_name":"Small RNA","level":4,"score":0.4823572039604187},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.4491347372531891},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4448888301849365},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2295784056186676},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.06194600462913513}],"mesh":[{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009928","descriptor_name":"Organ Specificity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010012","descriptor_name":"Osteogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D050156","descriptor_name":"Adipogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D050659","descriptor_name":"Core Binding Factor Alpha 1 Subunit","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D050659","descriptor_name":"Core Binding Factor Alpha 1 Subunit","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/gb-2011-12-7-r64","doi":"https://doi.org/10.1186/gb-2011-12-7-r64","is_oa":true,"landing_page_url":"https://doi.org/10.1186/gb-2011-12-7-r64","pdf_url":"https://genomebiology.biomedcentral.com/counter/pdf/10.1186/gb-2011-12-7-r64","source":{"id":"https://openalex.org/S81160022","display_name":"Genome biology","issn_l":"1465-6906","issn":["1465-6906","1465-6914","1474-7596","1474-760X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Biology","raw_type":"journal-article"},{"id":"pmid:21767385","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21767385","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3218826","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3218826/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Biol","raw_type":"Text"},{"id":"pmh:oai:HAL:hal-00626107v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-00626107","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Genome Biology, 2011, 12 (7), pp.R64. ⟨10.1186/gb-2011-12-7-r64⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.226.8290","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.226.8290","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://genomebiology.com/content/pdf/gb-2011-12-7-r64.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1186/gb-2011-12-7-r64","doi":"https://doi.org/10.1186/gb-2011-12-7-r64","is_oa":true,"landing_page_url":"https://doi.org/10.1186/gb-2011-12-7-r64","pdf_url":"https://genomebiology.biomedcentral.com/counter/pdf/10.1186/gb-2011-12-7-r64","source":{"id":"https://openalex.org/S81160022","display_name":"Genome biology","issn_l":"1465-6906","issn":["1465-6906","1465-6914","1474-7596","1474-760X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309749","display_name":"Association pour la Recherche sur le Cancer","ror":"https://ror.org/0489qz649"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"},{"id":"https://openalex.org/F4320323807","display_name":"Institut National Du Cancer","ror":"https://ror.org/03m8vkq32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139204931.pdf","grobid_xml":"https://content.openalex.org/works/W2139204931.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W149089276","https://openalex.org/W1554847406","https://openalex.org/W1844685923","https://openalex.org/W1971680163","https://openalex.org/W1975998449","https://openalex.org/W1976878696","https://openalex.org/W1981478386","https://openalex.org/W1983641973","https://openalex.org/W1986167698","https://openalex.org/W1989020172","https://openalex.org/W1990792003","https://openalex.org/W1997386949","https://openalex.org/W2007638378","https://openalex.org/W2017435031","https://openalex.org/W2019011732","https://openalex.org/W2029782351","https://openalex.org/W2035832775","https://openalex.org/W2040845651","https://openalex.org/W2047413348","https://openalex.org/W2047798798","https://openalex.org/W2052098392","https://openalex.org/W2062750166","https://openalex.org/W2085442947","https://openalex.org/W2097899015","https://openalex.org/W2098285533","https://openalex.org/W2102392334","https://openalex.org/W2106039274","https://openalex.org/W2107503723","https://openalex.org/W2119859961","https://openalex.org/W2123511906","https://openalex.org/W2129651187","https://openalex.org/W2143168180","https://openalex.org/W2143516374","https://openalex.org/W2146278947","https://openalex.org/W2149476024","https://openalex.org/W2166094946","https://openalex.org/W2168813512","https://openalex.org/W2170550295","https://openalex.org/W2184392836","https://openalex.org/W2914018683"],"related_works":["https://openalex.org/W1993174948","https://openalex.org/W2020911494","https://openalex.org/W2048013285","https://openalex.org/W2116726599","https://openalex.org/W2332662749","https://openalex.org/W2043208380","https://openalex.org/W2270705630","https://openalex.org/W1780918613","https://openalex.org/W3212364281"],"abstract_inverted_index":{"BACKGROUND:":[0],"In":[1],"severe":[2],"obesity,":[3],"as":[4,6,112,203],"well":[5],"in":[7,21,65,80,138,199],"normal":[8],"development,":[9],"the":[10,16,30,42,74,81,109,123,136,147,170,178,192,215,218],"growth":[11],"of":[12,18,32,35,41,54,76,83,101,146,154,180,184,217,235],"adipose":[13,55,102,204,236],"tissue":[14,56],"is":[15,27,47],"result":[17],"an":[19,51],"increase":[20],"adipocyte":[22,200],"size":[23],"and":[24,133,156,167,174],"numbers,":[25],"which":[26,126,135,227],"underlain":[28],"by":[29,226],"stimulation":[31],"adipogenic":[33,84,131,233],"differentiation":[34,67,132,234],"precursor":[36],"cells.":[37,105,239],"A":[38],"better":[39],"knowledge":[40],"pathways":[43],"that":[44,95,164,191],"regulate":[45],"adipogenesis":[46,100,139,176],"therefore":[48],"essential":[49],"for":[50,134],"improved":[52],"understanding":[53],"expansion.":[57],"As":[58],"microRNAs":[59],"(miRNAs)":[60],"have":[61],"a":[62,113,196,223],"critical":[63],"role":[64,75,137,198],"many":[66],"processes,":[68],"our":[69,120,188],"study":[70,121],"aimed":[71],"to":[72,91,232],"identify":[73,92],"miRNA-mediated":[77],"gene":[78],"silencing":[79],"regulation":[82],"differentiation.":[85],"RESULTS:":[86],"We":[87,117,161],"used":[88],"deep":[89],"sequencing":[90],"small":[93],"RNAs":[94],"are":[96],"differentially":[97],"expressed":[98],"during":[99,130],"tissue-derived":[103,205,237],"stem":[104,206,238],"This":[106],"approach":[107],"revealed":[108],"un-annotated":[110],"miR-642a-3p":[111],"highly":[114],"adipocyte-specific":[115],"miRNA.":[116],"then":[118],"focused":[119],"on":[122],"miR-30":[124,148,193,228],"family,":[125],"was":[127],"also":[128],"up-regulated":[129],"had":[140],"not":[141],"yet":[142],"been":[143],"elucidated.":[144],"Inhibition":[145],"family":[149,194],"blocked":[150],"adipogenesis,":[151],"whilst":[152],"over-expression":[153],"miR-30a":[155,166],"miR-30d":[157,168],"stimulated":[158],"this":[159,181],"process.":[160],"additionally":[162],"showed":[163],"both":[165],"target":[169],"transcription":[171],"factor":[172],"RUNX2,":[173],"stimulate":[175],"via":[177],"modulation":[179],"major":[182],"regulator":[183,220],"osteogenesis.":[185],"CONCLUSIONS:":[186],"Overall,":[187],"data":[189],"suggest":[190],"plays":[195],"central":[197],"development.":[201],"Moreover,":[202],"cells":[207],"can":[208],"differentiate":[209],"into":[210],"either":[211],"adipocytes":[212],"or":[213],"osteoblasts,":[214],"down-regulation":[216],"osteogenesis":[219],"RUNX2":[221],"represents":[222],"plausible":[224],"mechanism":[225],"miRNAs":[229],"may":[230],"contribute":[231]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":21},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":21},{"year":2018,"cited_by_count":16},{"year":2017,"cited_by_count":22},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":32},{"year":2014,"cited_by_count":17},{"year":2013,"cited_by_count":24},{"year":2012,"cited_by_count":18}],"updated_date":"2026-11-15T12:55:33.944570","created_date":"2016-06-24T00:00:00"}