{"id":"https://openalex.org/W2139195186","doi":"https://doi.org/10.1186/1475-2875-13-93","title":"Towards a comprehensive Plasmodium falciparum merozoite cell surface and secreted recombinant protein library","display_name":"Towards a comprehensive Plasmodium falciparum merozoite cell surface and secreted recombinant protein library","publication_year":2014,"publication_date":"2014-03-12","ids":{"openalex":"https://openalex.org/W2139195186","doi":"https://doi.org/10.1186/1475-2875-13-93","mag":"2139195186","pmid":"https://pubmed.ncbi.nlm.nih.gov/24620899","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3995786"},"language":"en","primary_location":{"id":"doi:10.1186/1475-2875-13-93","doi":"https://doi.org/10.1186/1475-2875-13-93","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1475-2875-13-93","pdf_url":"https://malariajournal.biomedcentral.com/counter/pdf/10.1186/1475-2875-13-93","source":{"id":"https://openalex.org/S93003929","display_name":"Malaria Journal","issn_l":"1475-2875","issn":["1475-2875"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malaria Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://malariajournal.biomedcentral.com/counter/pdf/10.1186/1475-2875-13-93","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007970285","display_name":"\u0396\u03ae\u03bd\u03c9\u03bd \u0396\u03ae\u03bd\u03c9\u03bd\u03bf\u03c2","orcid":"https://orcid.org/0000-0003-3301-1809","observed_orcids":["https://orcid.org/0000-0003-3301-1809"]},"institutions":[{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Zenon A Zenonos","raw_affiliation_strings":["Cell Surface Signalling Laboratory, Wellcome Trust Sanger Institute, Cambridge, CB10 1SA, UK","Malaria Programme, Wellcome Trust Sanger Institute, Cambridge, CB10 1SA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cell Surface Signalling Laboratory, Wellcome Trust Sanger Institute, Cambridge, CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]},{"raw_affiliation_string":"Malaria Programme, Wellcome Trust Sanger Institute, Cambridge, CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062767154","display_name":"Julian C. Rayner","orcid":"https://orcid.org/0000-0002-9835-1014","observed_orcids":["https://orcid.org/0000-0002-9835-1014"]},"institutions":[{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Julian C Rayner","raw_affiliation_strings":["Malaria Programme, Wellcome Trust Sanger Institute, Cambridge, CB10 1SA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Malaria Programme, Wellcome Trust Sanger Institute, Cambridge, CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029330044","display_name":"Gavin James Wright","orcid":"https://orcid.org/0000-0003-0537-0863","observed_orcids":["https://orcid.org/0000-0003-0537-0863"]},"institutions":[{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Gavin J Wright","raw_affiliation_strings":["Cell Surface Signalling Laboratory, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK. gw2@sanger.ac.uk","Cell Surface Signalling Laboratory, Wellcome Trust Sanger Institute, Cambridge, CB10 1SA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cell Surface Signalling Laboratory, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK. gw2@sanger.ac.uk","institution_ids":["https://openalex.org/I2802476451"]},{"raw_affiliation_string":"Cell Surface Signalling Laboratory, Wellcome Trust Sanger Institute, Cambridge, CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5029330044"],"corresponding_institution_ids":["https://openalex.org/I2802476451"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":2890,"currency":"USD","value_usd":2890},"fwci":2.2628,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.88373387,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"13","issue":"1","first_page":"93","last_page":"93"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12685","display_name":"Phytochemical compounds biological activities","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.9990000128746033},{"id":"https://openalex.org/keywords/secreted-proteins","display_name":"secreted proteins","score":0.9819999933242798},{"id":"https://openalex.org/keywords/malaria-vaccine-targets","display_name":"malaria vaccine targets","score":0.9010000228881836},{"id":"https://openalex.org/keywords/schizogony","display_name":"schizogony","score":0.8420000076293945},{"id":"https://openalex.org/keywords/extracellular-proteins","display_name":"extracellular proteins","score":0.6579999923706055},{"id":"https://openalex.org/keywords/genome-wide-expression-profiling","display_name":"genome-wide expression profiling","score":0.7009999752044678}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7454630136489868},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.6780170202255249},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.6770204305648804},{"id":"https://openalex.org/C1009742","wikidata":"https://www.wikidata.org/wiki/Q5333998","display_name":"Ectodomain","level":3,"score":0.5719167590141296},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.5001180171966553},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.49761131405830383},{"id":"https://openalex.org/C2781034427","wikidata":"https://www.wikidata.org/wiki/Q6741353","display_name":"Malaria vaccine","level":4,"score":0.4518446922302246},{"id":"https://openalex.org/C2909193768","wikidata":"https://www.wikidata.org/wiki/Q929080","display_name":"Schizogony","level":4,"score":0.43250784277915955},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.34289461374282837},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.30001527070999146},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2036271095275879},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19370371103286743},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1225510835647583},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.09683024883270264}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D052940","descriptor_name":"Merozoites","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1186/1475-2875-13-93","doi":"https://doi.org/10.1186/1475-2875-13-93","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1475-2875-13-93","pdf_url":"https://malariajournal.biomedcentral.com/counter/pdf/10.1186/1475-2875-13-93","source":{"id":"https://openalex.org/S93003929","display_name":"Malaria Journal","issn_l":"1475-2875","issn":["1475-2875"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malaria Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2973185","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3995786","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3995786","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3995786","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malar J","raw_type":"Text"},{"id":"pmid:24620899","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24620899","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malaria journal","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.815.5977","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.815.5977","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/44/39/1475-2875-13-93.PMC3995786.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1186/1475-2875-13-93","doi":"https://doi.org/10.1186/1475-2875-13-93","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1475-2875-13-93","pdf_url":"https://malariajournal.biomedcentral.com/counter/pdf/10.1186/1475-2875-13-93","source":{"id":"https://openalex.org/S93003929","display_name":"Malaria Journal","issn_l":"1475-2875","issn":["1475-2875"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Malaria Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8666890344","display_name":"Wellcome Trust Sanger Institute - generic account for deposition of all core- funded research papers","funder_award_id":"098051","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G8811728393","display_name":"A comprehensive survey of protein-protein interactions between Plasmodium falciparum merozoites and human receptors","funder_award_id":"MR/J002283/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139195186.pdf","grobid_xml":"https://content.openalex.org/works/W2139195186.grobid-xml"},"referenced_works_count":65,"referenced_works":["https://openalex.org/W1569413678","https://openalex.org/W1569979849","https://openalex.org/W1891682296","https://openalex.org/W1964149115","https://openalex.org/W1964366824","https://openalex.org/W1972854128","https://openalex.org/W1973771056","https://openalex.org/W1975881900","https://openalex.org/W1978455510","https://openalex.org/W1980530530","https://openalex.org/W1982633554","https://openalex.org/W1984996167","https://openalex.org/W1985652790","https://openalex.org/W1985878579","https://openalex.org/W1992084968","https://openalex.org/W1994031108","https://openalex.org/W1997758393","https://openalex.org/W1998834739","https://openalex.org/W2003480560","https://openalex.org/W2006999012","https://openalex.org/W2010567241","https://openalex.org/W2019851585","https://openalex.org/W2026483075","https://openalex.org/W2027834647","https://openalex.org/W2034911186","https://openalex.org/W2036558143","https://openalex.org/W2039227742","https://openalex.org/W2039735909","https://openalex.org/W2045503393","https://openalex.org/W2049551663","https://openalex.org/W2049655197","https://openalex.org/W2056387142","https://openalex.org/W2057223388","https://openalex.org/W2058906314","https://openalex.org/W2062502531","https://openalex.org/W2065087697","https://openalex.org/W2070692447","https://openalex.org/W2083280521","https://openalex.org/W2088822039","https://openalex.org/W2090211342","https://openalex.org/W2091823981","https://openalex.org/W2093426037","https://openalex.org/W2094201044","https://openalex.org/W2095554063","https://openalex.org/W2099299834","https://openalex.org/W2112047656","https://openalex.org/W2112931002","https://openalex.org/W2114083522","https://openalex.org/W2119376399","https://openalex.org/W2120659498","https://openalex.org/W2127961747","https://openalex.org/W2130314959","https://openalex.org/W2135162400","https://openalex.org/W2136797050","https://openalex.org/W2141885858","https://openalex.org/W2144405512","https://openalex.org/W2146205686","https://openalex.org/W2158684589","https://openalex.org/W2163432257","https://openalex.org/W2163443861","https://openalex.org/W2165647350","https://openalex.org/W2166726458","https://openalex.org/W2803337115","https://openalex.org/W4229690720","https://openalex.org/W4320301318"],"related_works":["https://openalex.org/W7095200510","https://openalex.org/W2119376399","https://openalex.org/W2005605759","https://openalex.org/W7096929430","https://openalex.org/W1983592347","https://openalex.org/W2579809462","https://openalex.org/W2219552342","https://openalex.org/W2326649681","https://openalex.org/W2144865403","https://openalex.org/W2142384652"],"abstract_inverted_index":{"BACKGROUND:":[0],"Plasmodium":[1,84,238],"falciparum":[2,114,253,282],"is":[3],"the":[4,25,48,78,110,182,190,193,208,219,234,298,304,311],"aetiological":[5],"agent":[6],"for":[7,13,118,189],"malaria,":[8],"a":[9,66,74,93,102,244,293],"deadly":[10],"infectious":[11],"disease":[12],"which":[14,265,285],"no":[15],"vaccine":[16,34,120,317],"has":[17,54],"yet":[18],"been":[19,31,55],"licensed.":[20],"The":[21],"proteins":[22,64,85,108,117,134,194,213,239,258,302],"displayed":[23],"on":[24],"merozoite":[26,97,115,220,283],"cell":[27,167,256],"surface":[28,168,257],"have":[29],"long":[30],"considered":[32],"attractive":[33],"targets":[35,53],"because":[36],"of":[37,51,81,95,106,112,192,210,218,250,279,300,307,314],"their":[38,139,196],"direct":[39],"exposure":[40],"to":[41,91,129,163,224,268],"host":[42],"antibodies;":[43],"however,":[44],"progress":[45],"in":[46,65,296],"understanding":[47],"functional":[49,82,122],"role":[50],"these":[52,63,301],"hindered":[56],"by":[57,146,187,261],"technical":[58],"challenges":[59],"associated":[60],"with":[61,181],"expressing":[62],"functionally":[67],"active":[68],"recombinant":[69,107,176,212,251],"form.":[70],"To":[71,100,228],"address":[72],"this,":[73],"method":[75],"that":[76,155],"enables":[77],"systematic":[79,119,230],"expression":[80,125,142,197],"extracellular":[83,116,280],"was":[86,127,185,214,259],"previously":[87],"developed,":[88],"and":[89,121,138,141,149,161,166,172,195,216,255,273,309],"used":[90,128],"create":[92],"library":[94,105,249],"42":[96],"proteins.":[98,177],"METHODS:":[99],"compile":[101],"more":[103],"comprehensive":[104],"representing":[109],"repertoire":[111],"P.":[113,252,281],"studies,":[123],"genome-wide":[124],"profiling":[126],"identify":[130],"additional":[131,153,263],"candidates.":[132,318],"Candidate":[133],"were":[135,144,156,170,199,222,240,266],"recombinantly":[136],"produced":[137],"integrity":[140],"levels":[143,198,272],"tested":[145],"Western":[147],"blotting":[148],"ELISA.":[150],"RESULTS:":[151],"Twenty-five":[152],"genes":[154],"upregulated":[157],"during":[158,303],"late":[159],"schizogony,":[160],"predicted":[162],"encode":[164],"secreted":[165,254],"proteins,":[169,264,284],"identified":[171],"expressed":[173],"as":[174],"soluble":[175],"A":[178,248],"band":[179],"consistent":[180],"entire":[183,235],"ectodomain":[184],"observed":[186],"immunoblotting":[188],"majority":[191],"quantified.":[200],"By":[201],"using":[202,243],"sera":[203],"from":[204],"malaria-exposed":[205],"immune":[206],"adults,":[207],"immunoreactivity":[209],"20":[211,262],"assessed,":[215],"most":[217],"ligands":[221],"found":[223],"carry":[225],"heat-labile":[226],"epitopes.":[227,276],"facilitate":[229,310],"comparative":[231,312],"studies":[232],"across":[233],"library,":[236],"multiple":[237],"simultaneously":[241],"purified":[242],"custom-made":[245],"platform.":[246],"CONCLUSIONS:":[247],"expanded":[260],"shown":[267],"express":[269],"at":[270],"usable":[271],"contain":[274],"conformational":[275],"This":[277],"resource":[278],"now":[286],"contains":[287],"62":[288],"full-length":[289],"ectodomains,":[290],"will":[291],"be":[292],"valuable":[294],"tool":[295],"elucidating":[297],"function":[299],"blood":[305,315],"stages":[306],"infection,":[308],"assessment":[313],"stage":[316]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}