{"id":"https://openalex.org/W2139114196","doi":"https://doi.org/10.1590/s0103-05822013000400016","title":"Antioxidant vitamins in the context of nonalcoholic fatty liver disease in obese children and adolescents","display_name":"Antioxidant vitamins in the context of nonalcoholic fatty liver disease in obese children and adolescents","publication_year":2013,"publication_date":"2013-12-01","ids":{"openalex":"https://openalex.org/W2139114196","doi":"https://doi.org/10.1590/s0103-05822013000400016","mag":"2139114196","pmid":"https://pubmed.ncbi.nlm.nih.gov/24473959","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4183033"},"language":"en","primary_location":{"id":"doi:10.1590/s0103-05822013000400016","doi":"https://doi.org/10.1590/s0103-05822013000400016","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0103-05822013000400016","pdf_url":"http://www.scielo.br/pdf/rpp/v31n4/0103-0582-rpp-31-04-00523.pdf","source":{"id":"https://openalex.org/S123735288","display_name":"Revista Paulista de Pediatria","issn_l":"0103-0582","issn":["0103-0582","1984-0462"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","medline","poland-70","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Paulista de Pediatria","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.scielo.br/pdf/rpp/v31n4/0103-0582-rpp-31-04-00523.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012019898","display_name":"F\u00e1bio da Veiga Ued","orcid":"https://orcid.org/0000-0003-2184-4977","observed_orcids":["https://orcid.org/0000-0003-2184-4977"]},"institutions":[{"id":"https://openalex.org/I4210106570","display_name":"Universidade Federal do Tri\u00e2ngulo Mineiro","ror":"https://ror.org/01av3m334","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210106570"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"F\u00e1bio da Veiga Ued","raw_affiliation_strings":["UFTM,  Brasil","UFTM, UberabaMG, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UFTM,  Brasil","institution_ids":["https://openalex.org/I4210106570"]},{"raw_affiliation_string":"UFTM, UberabaMG, Brasil","institution_ids":["https://openalex.org/I4210106570"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030197927","display_name":"Virg\u00ednia Resende Silva Weffort","orcid":"https://orcid.org/0000-0002-2890-4744","observed_orcids":["https://orcid.org/0000-0002-2890-4744"]},"institutions":[{"id":"https://openalex.org/I4210106570","display_name":"Universidade Federal do Tri\u00e2ngulo Mineiro","ror":"https://ror.org/01av3m334","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210106570"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Virg\u00ednia Resende S. Weffort","raw_affiliation_strings":["UFTM,  Brasil","UFTM, UberabaMG, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UFTM,  Brasil","institution_ids":["https://openalex.org/I4210106570"]},{"raw_affiliation_string":"UFTM, UberabaMG, Brasil","institution_ids":["https://openalex.org/I4210106570"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5012019898"],"corresponding_institution_ids":["https://openalex.org/I4210106570"],"apc_list":null,"apc_paid":null,"fwci":0.0374,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.04795205,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"31","issue":"4","first_page":"523","last_page":"530"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antioxidant-vitamins","display_name":"antioxidant vitamins","score":0.9509999752044678},{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.996999979019165},{"id":"https://openalex.org/keywords/childhood-obesity","display_name":"childhood obesity","score":0.8130000233650208},{"id":"https://openalex.org/keywords/adolescents","display_name":"adolescents","score":0.6290000081062317},{"id":"https://openalex.org/keywords/vitamin-supplementation","display_name":"vitamin supplementation","score":0.8679999709129333},{"id":"https://openalex.org/keywords/food-consumption","display_name":"dietary intake","score":0.8500000238418579},{"id":"https://openalex.org/keywords/plasma-vitamin-levels","display_name":"plasma vitamin levels","score":0.8989999890327454},{"id":"https://openalex.org/keywords/steatohepatitis","display_name":"steatohepatitis","score":0.8220000267028809},{"id":"https://openalex.org/keywords/simple-steatosis","display_name":"simple steatosis","score":0.8259999752044678},{"id":"https://openalex.org/keywords/alanine-aminotransferase","display_name":"alanine aminotransferase","score":0.9649999737739563},{"id":"https://openalex.org/keywords/lifestyle-modification","display_name":"lifestyle modification","score":0.7070000171661377},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.9520000219345093}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8023107051849365},{"id":"https://openalex.org/C2776954865","wikidata":"https://www.wikidata.org/wiki/Q1546498","display_name":"Nonalcoholic fatty liver disease","level":4,"score":0.749382495880127},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6061656475067139},{"id":"https://openalex.org/C2777551382","wikidata":"https://www.wikidata.org/wiki/Q141180","display_name":"Vitamin E","level":3,"score":0.5858575105667114},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.5268310904502869},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5033060908317566},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.47360730171203613},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4559425115585327},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.4419423043727875},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.42516887187957764},{"id":"https://openalex.org/C2780022331","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Vitamin C","level":2,"score":0.4190908670425415},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.39305371046066284},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.2898569405078888},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10981205105781555},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09728667140007019},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014815","descriptor_name":"Vitamins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1590/s0103-05822013000400016","doi":"https://doi.org/10.1590/s0103-05822013000400016","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0103-05822013000400016","pdf_url":"http://www.scielo.br/pdf/rpp/v31n4/0103-0582-rpp-31-04-00523.pdf","source":{"id":"https://openalex.org/S123735288","display_name":"Revista Paulista de Pediatria","issn_l":"0103-0582","issn":["0103-0582","1984-0462"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","medline","poland-70","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Paulista de Pediatria","raw_type":"journal-article"},{"id":"pmid:24473959","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24473959","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4183033","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4183033/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rev Paul Pediatr","raw_type":"Text"},{"id":"pmh:oai:scielo:S0103-05822013000400523","doi":null,"is_oa":true,"landing_page_url":"http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822013000400523","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Paulista de Pediatria v.31 n.4 2013","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2433637","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822013000400523","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista Paulista de Pediatria v.31 n.4 2013","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:00f2ff54bbf140978a845408ba7aa17c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/00f2ff54bbf140978a845408ba7aa17c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista Paulista de Pediatria, Vol 31, Iss 4, Pp 523-530 (2013)","raw_type":"article"},{"id":"pmh:oai:redalyc.org:406038970016","doi":null,"is_oa":false,"landing_page_url":"https://www.redalyc.org/articulo.oa?id=406038970016","pdf_url":null,"source":{"id":"https://openalex.org/S4377196100","display_name":"Redalyc (Universidad Aut\u00f3noma del Estado de M\u00e9xico)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I179647637","host_organization_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","host_organization_lineage":["https://openalex.org/I179647637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista Paulista de Pediatria (Brasil) Num.4 Vol.31","raw_type":"art\u00edculo cient\u00edfico"}],"best_oa_location":{"id":"doi:10.1590/s0103-05822013000400016","doi":"https://doi.org/10.1590/s0103-05822013000400016","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0103-05822013000400016","pdf_url":"http://www.scielo.br/pdf/rpp/v31n4/0103-0582-rpp-31-04-00523.pdf","source":{"id":"https://openalex.org/S123735288","display_name":"Revista Paulista de Pediatria","issn_l":"0103-0582","issn":["0103-0582","1984-0462"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","medline","poland-70","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Paulista de Pediatria","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139114196.pdf","grobid_xml":"https://content.openalex.org/works/W2139114196.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W43769036","https://openalex.org/W65224755","https://openalex.org/W1968396962","https://openalex.org/W1971085971","https://openalex.org/W1987763288","https://openalex.org/W1994173695","https://openalex.org/W1994825229","https://openalex.org/W2011164640","https://openalex.org/W2021181366","https://openalex.org/W2021182659","https://openalex.org/W2031434506","https://openalex.org/W2036196540","https://openalex.org/W2038192950","https://openalex.org/W2047513387","https://openalex.org/W2057355518","https://openalex.org/W2074327889","https://openalex.org/W2079644222","https://openalex.org/W2079653703","https://openalex.org/W2079973141","https://openalex.org/W2085870626","https://openalex.org/W2086389847","https://openalex.org/W2090036126","https://openalex.org/W2090802204","https://openalex.org/W2103256145","https://openalex.org/W2133294251","https://openalex.org/W2134723464","https://openalex.org/W2136847524","https://openalex.org/W2142681741","https://openalex.org/W2151463315","https://openalex.org/W2157671355","https://openalex.org/W2164325911","https://openalex.org/W2167084958","https://openalex.org/W2517988957"],"related_works":["https://openalex.org/W7120743831","https://openalex.org/W4407351376","https://openalex.org/W1555942679","https://openalex.org/W2792119920","https://openalex.org/W2945813467","https://openalex.org/W2945322843","https://openalex.org/W4319442974","https://openalex.org/W2021182659","https://openalex.org/W2304711892","https://openalex.org/W4231557789"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1,53],"review":[2],"the":[3,6,13,55,57,64,122,144,149,155,201,204],"literature":[4],"on":[5],"importance":[7],"of":[8,15,119,158],"antioxidant":[9,104,184],"vitamins,":[10,120],"analyzed":[11],"in":[12,29,45,78,108,113,124,133,137,171,186,195],"context":[14],"dietary":[16,100,117],"intake,":[17],"its":[18,22],"plasma":[19],"levels,":[20],"and":[21,32,50,69,81,102,121,136,154,161],"current":[23],"use":[24],"as":[25,148],"a":[26,98,130],"supplementation":[27,141,185],"treatment":[28],"obese":[30],"children":[31],"adolescents":[33],"with":[34,83,115,129,188],"nonalcoholic":[35],"fatty":[36],"liver":[37,134],"disease.":[38],"DATA":[39,89],"SOURCES:":[40],"The":[41,71,95,111,193],"articles":[42,76],"were":[43,93,127,167],"identified":[44],"Lilacs,":[46],"Ibecs,":[47],"SciELO,":[48],"PubMed/Medline,":[49],"Scopus":[51],"databases.":[52],"conduct":[54],"survey,":[56],"\"fatty":[58],"liver\"":[59],"descriptor":[60],"was":[61,73],"associated":[62,128],"to":[63,75,179,182,198],"following":[65],"words:":[66],"\"children\",":[67],"\"antioxidants\"":[68],"\"vitamins\".":[70],"search":[72],"limited":[74],"written":[77],"Portuguese,":[79],"Spanish":[80],"English,":[82],"publication":[84],"date":[85],"until":[86],"December,":[87],"2012.":[88],"SYNTHESIS:":[90],"Six":[91],"studies":[92],"selected.":[94],"survey":[96],"revealed":[97],"low":[99,103],"intake":[101,118],"vitamins":[105],"serum":[106,152],"levels":[107,153],"this":[109],"population.":[110],"changes":[112,194],"lifestyle,":[114],"adequate":[116],"increase":[123],"physical":[125],"activity":[126],"significant":[131,170],"improvement":[132],"histology":[135],"laboratory":[138],"tests.":[139],"Vitamin":[140],"also":[142],"improved":[143],"disease":[145],"progression":[146],"markers,":[147],"alanine":[150],"aminotransferase":[151],"histological":[156],"characteristics":[157],"lobular":[159],"inflammation":[160],"hepatocellular":[162],"damage.":[163],"However,":[164],"these":[165],"improvements":[166],"not":[168],"statistically":[169],"all":[172],"studies.":[173],"CONCLUSIONS:":[174],"There":[175],"is":[176],"insufficient":[177],"evidence":[178],"recommend":[180],"or":[181,191],"refute":[183],"patients":[187],"simple":[189],"steatosis":[190],"steatohepatitis.":[192],"lifestyle":[196],"seem":[197],"be,":[199],"at":[200],"present":[202],"time,":[203],"more":[205],"advisable":[206],"therapy.":[207]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}