{"id":"https://openalex.org/W2139113680","doi":null,"title":"Une approche phylo-HMM pour la recherche de s\u00e9quences","display_name":"Une approche phylo-HMM pour la recherche de s\u00e9quences","publication_year":2008,"publication_date":"2008-06-30","ids":{"openalex":"https://openalex.org/W2139113680","mag":"2139113680"},"language":"fr","primary_location":{"id":"pmh:oai:HAL:lirmm-00324451v1","doi":null,"is_oa":true,"landing_page_url":"https://hal-lirmm.ccsd.cnrs.fr/lirmm-00324451","pdf_url":"https://hal-lirmm.ccsd.cnrs.fr/lirmm-00324451v1/document","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www2.lifl.fr/jobim2008/","raw_type":"info:eu-repo/semantics/conferenceObject"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hal-lirmm.ccsd.cnrs.fr/lirmm-00324451v1/document","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067982071","display_name":"Jean-Baka Domelevo-Entfellner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I11559806","display_name":"\u00c9cole Normale Sup\u00e9rieure Paris-Saclay","ror":"https://ror.org/00hx6zz33","country_code":"FR","type":"education","lineage":["https://openalex.org/I11559806","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210101743","display_name":"Laboratoire d'Informatique, de Robotique et de Micro\u00e9lectronique de Montpellier","ror":"https://ror.org/013yean28","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I151295451","https://openalex.org/I19894307","https://openalex.org/I4210101743","https://openalex.org/I4210159245","https://openalex.org/I4405261681"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Domelevo Entfellner, Jean-Baka","raw_affiliation_strings":["ENS Cachan , Antenne de Bretagne , 35170 Bruz , France","M\u00e9thodes et Algorithmes pour la Bioinformatique LIRMM , CNRS-UM2 , 161 rue Ada , 34392 Montpellier Cedex 5 , France","Laboratoire d'Informatique, de Robotique et de Micro\u00e9lectronique de Montpellier"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ENS Cachan , Antenne de Bretagne , 35170 Bruz , France","institution_ids":["https://openalex.org/I11559806"]},{"raw_affiliation_string":"M\u00e9thodes et Algorithmes pour la Bioinformatique LIRMM , CNRS-UM2 , 161 rue Ada , 34392 Montpellier Cedex 5 , France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210101743"]},{"raw_affiliation_string":"Laboratoire d'Informatique, de Robotique et de Micro\u00e9lectronique de Montpellier","institution_ids":["https://openalex.org/I4210101743"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078068308","display_name":"Olivier Gascuel","orcid":"https://orcid.org/0000-0002-9412-9723","observed_orcids":["https://orcid.org/0000-0002-9412-9723"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210101743","display_name":"Laboratoire d'Informatique, de Robotique et de Micro\u00e9lectronique de Montpellier","ror":"https://ror.org/013yean28","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I151295451","https://openalex.org/I19894307","https://openalex.org/I4210101743","https://openalex.org/I4210159245","https://openalex.org/I4405261681"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gascuel, Olivier","raw_affiliation_strings":["M\u00e9thodes et Algorithmes pour la Bioinformatique LIRMM , CNRS-UM2 , 161 rue Ada , 34392 Montpellier Cedex 5 , France","M\u00e9thodes et Algorithmes pour la Bioinformatique"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M\u00e9thodes et Algorithmes pour la Bioinformatique LIRMM , CNRS-UM2 , 161 rue Ada , 34392 Montpellier Cedex 5 , France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210101743"]},{"raw_affiliation_string":"M\u00e9thodes et Algorithmes pour la Bioinformatique","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"408","issue":null,"first_page":"133","last_page":"139"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2614","display_name":"Theoretical Computer Science"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sequence-database-searching","display_name":"sequence database searching","score":0.7599999904632568},{"id":"https://openalex.org/keywords/protein-families","display_name":"protein families","score":0.8360000252723694},{"id":"https://openalex.org/keywords/genome-annotation","display_name":"genome annotation","score":0.7459999918937683},{"id":"https://openalex.org/keywords/profile-hmm","display_name":"HMM profiles","score":0.7540000081062317},{"id":"https://openalex.org/keywords/phylogeny","display_name":"phylogeny","score":0.5329999923706055},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.7369999885559082}],"concepts":[{"id":"https://openalex.org/C23224414","wikidata":"https://www.wikidata.org/wiki/Q176769","display_name":"Hidden Markov model","level":2,"score":0.9106920957565308},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.6683405637741089},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5114890336990356},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4737609028816223},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4666315019130707},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.43684232234954834},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4305576682090759},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3897048532962799},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.35360538959503174},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3264060616493225},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2925337255001068},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16347506642341614}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:HAL:lirmm-00324451v1","doi":null,"is_oa":true,"landing_page_url":"https://hal-lirmm.ccsd.cnrs.fr/lirmm-00324451","pdf_url":"https://hal-lirmm.ccsd.cnrs.fr/lirmm-00324451v1/document","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www2.lifl.fr/jobim2008/","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":{"id":"pmh:oai:HAL:lirmm-00324451v1","doi":null,"is_oa":true,"landing_page_url":"https://hal-lirmm.ccsd.cnrs.fr/lirmm-00324451","pdf_url":"https://hal-lirmm.ccsd.cnrs.fr/lirmm-00324451v1/document","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www2.lifl.fr/jobim2008/","raw_type":"info:eu-repo/semantics/conferenceObject"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139113680.pdf","grobid_xml":"https://content.openalex.org/works/W2139113680.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W1844951369","https://openalex.org/W2029833898","https://openalex.org/W2049633694","https://openalex.org/W2103546861","https://openalex.org/W2107010419","https://openalex.org/W2109437787","https://openalex.org/W2132926880","https://openalex.org/W2141885858","https://openalex.org/W2166444569","https://openalex.org/W3214380909","https://openalex.org/W7099666281"],"related_works":["https://openalex.org/W7058611900","https://openalex.org/W2099893032","https://openalex.org/W2127346557","https://openalex.org/W3099361427","https://openalex.org/W1996266138","https://openalex.org/W7099422821","https://openalex.org/W2570474257","https://openalex.org/W7095172932","https://openalex.org/W2625361022","https://openalex.org/W7098601520"],"abstract_inverted_index":{"We":[0],"introduce":[1],"a":[2,23,36,53,57],"new":[3],"type":[4],"of":[5,13,19,22,25,35,41],"phylogenetic":[6],"Hidden":[7],"Markov":[8],"Model,":[9],"combining":[10],"the":[11,17,20,33,42],"strength":[12],"usual":[14],"HMM":[15,65],"and":[16,56],"knowledge":[18],"phylogeny":[21],"family":[24],"sequences.We":[26],"use":[27],"such":[28],"models":[29],"to":[30,62],"look":[31],"into":[32],"genome":[34],"target":[37],"species":[38],"for":[39],"members":[40],"sequence":[43],"family.":[44],"Our":[45],"results":[46],"on":[47],"some":[48],"690":[49],"protein":[50],"families":[51],"show":[52],"better":[54,58],"sensitivity":[55],"specificity":[59],"when":[60],"compared":[61],"standard":[63],"profile":[64],"or":[66],"Blast":[67],"searchs.":[68]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}