{"id":"https://openalex.org/W2139088247","doi":"https://doi.org/10.1136/bmj.38226.719803.eb","title":"Combined use of rapid D-dimer testing and estimation of clinical probability in the diagnosis of deep vein thrombosis: systematic review","display_name":"Combined use of rapid D-dimer testing and estimation of clinical probability in the diagnosis of deep vein thrombosis: systematic review","publication_year":2004,"publication_date":"2004-09-21","ids":{"openalex":"https://openalex.org/W2139088247","doi":"https://doi.org/10.1136/bmj.38226.719803.eb","mag":"2139088247","pmid":"https://pubmed.ncbi.nlm.nih.gov/15383452","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/521568"},"language":"en","primary_location":{"id":"doi:10.1136/bmj.38226.719803.eb","doi":"https://doi.org/10.1136/bmj.38226.719803.eb","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.38226.719803.eb","pdf_url":"https://www.bmj.com/content/bmj/329/7470/821.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.bmj.com/content/bmj/329/7470/821.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041753743","display_name":"Tonya L. Fancher","orcid":"https://orcid.org/0000-0001-5486-6123","observed_orcids":["https://orcid.org/0000-0001-5486-6123"]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Tonya L Fancher","raw_affiliation_strings":["Division of General Medicine, University of California at Davis, Patient Support Services Building, Suite 2400, Sacramento, California 95817, USA. Tonya.Fancher@ucdmc.ucdavis.edu","Division of General Medicine, University of California at Davis, Patient Support Services Building, Suite 2400, Sacramento, California 95817, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General Medicine, University of California at Davis, Patient Support Services Building, Suite 2400, Sacramento, California 95817, USA. Tonya.Fancher@ucdmc.ucdavis.edu","institution_ids":["https://openalex.org/I4210160527","https://openalex.org/I84218800"]},{"raw_affiliation_string":"Division of General Medicine, University of California at Davis, Patient Support Services Building, Suite 2400, Sacramento, California 95817, USA","institution_ids":["https://openalex.org/I4210160527","https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107094717","display_name":"Richard H. R. White","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard H White","raw_affiliation_strings":["Division of General Medicine, University of California at Davis, Patient Support Services Building, Suite 2400, Sacramento, California 95817, USA","General Medicine, Geriatrics, and Bioethics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General Medicine, University of California at Davis, Patient Support Services Building, Suite 2400, Sacramento, California 95817, USA","institution_ids":["https://openalex.org/I4210160527","https://openalex.org/I84218800"]},{"raw_affiliation_string":"General Medicine, Geriatrics, and Bioethics","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031871819","display_name":"Richard L. Kravitz","orcid":"https://orcid.org/0000-0001-5575-529X","observed_orcids":["https://orcid.org/0000-0001-5575-529X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard L Kravitz","raw_affiliation_strings":["Center for Health Services Research in Primary Care, 2103 Stockton Blvd, Sacramento, CA 95817, USA","General Medicine, Geriatrics, and Bioethics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Health Services Research in Primary Care, 2103 Stockton Blvd, Sacramento, CA 95817, USA","institution_ids":[]},{"raw_affiliation_string":"General Medicine, Geriatrics, and Bioethics","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5041753743"],"corresponding_institution_ids":["https://openalex.org/I4210160527","https://openalex.org/I84218800"],"apc_list":null,"apc_paid":null,"fwci":2.5871,"has_fulltext":true,"cited_by_count":146,"citation_normalized_percentile":{"value":0.93959732,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"329","issue":"7470","first_page":"821","last_page":"821"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10926","display_name":"Peripheral Artery Disease Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deep-vein-thrombosis","display_name":"deep vein thrombosis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/d-dimer-testing","display_name":"D-dimer testing","score":0.8610000014305115},{"id":"https://openalex.org/keywords/clinical-probability","display_name":"clinical probability","score":0.8309999704360962},{"id":"https://openalex.org/keywords/venous-thromboembolism","display_name":"venous thromboembolism","score":0.8759999871253967},{"id":"https://openalex.org/keywords/diagnostic-exclusion","display_name":"diagnostic exclusion","score":0.5559999942779541},{"id":"https://openalex.org/keywords/outpatients","display_name":"outpatients","score":0.8989999890327454},{"id":"https://openalex.org/keywords/lower-extremity-thrombosis","display_name":"lower extremity thrombosis","score":0.8759999871253967}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.854848325252533},{"id":"https://openalex.org/C2779519742","wikidata":"https://www.wikidata.org/wiki/Q198526","display_name":"D-dimer","level":2,"score":0.795556366443634},{"id":"https://openalex.org/C2778959117","wikidata":"https://www.wikidata.org/wiki/Q430892","display_name":"Deep vein","level":3,"score":0.7892863154411316},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.7361694574356079},{"id":"https://openalex.org/C174446222","wikidata":"https://www.wikidata.org/wiki/Q7239190","display_name":"Pre- and post-test probability","level":2,"score":0.6859883069992065},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6441094875335693},{"id":"https://openalex.org/C2780011451","wikidata":"https://www.wikidata.org/wiki/Q2751330","display_name":"Venous thrombosis","level":3,"score":0.6429479718208313},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.4906657934188843},{"id":"https://openalex.org/C2777202286","wikidata":"https://www.wikidata.org/wiki/Q9609","display_name":"Vein","level":2,"score":0.4273574948310852},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4193428158760071},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3872048556804657},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2530844807624817},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D005338","descriptor_name":"Fibrin Fibrinogen Degradation Products","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D020246","descriptor_name":"Venous Thrombosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true}],"locations_count":9,"locations":[{"id":"doi:10.1136/bmj.38226.719803.eb","doi":"https://doi.org/10.1136/bmj.38226.719803.eb","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.38226.719803.eb","pdf_url":"https://www.bmj.com/content/bmj/329/7470/821.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:264189","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC529397","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:1993328","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/521568","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:15383452","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15383452","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ (Clinical research ed.)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:521568","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC521568/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:529397","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC529397/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"Text"},{"id":"pmh:oai:open-archive.highwire.org:bmj:329/7470/821","doi":null,"is_oa":false,"landing_page_url":"http://www.bmj.com/cgi/content/short/329/7470/821","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:open-archive.highwire.org:bmj:bmj.38226.719803.EBv1","doi":null,"is_oa":false,"landing_page_url":"http://www.bmj.com/cgi/content/short/bmj.38226.719803.EBv1","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"mag:2186270180","doi":null,"is_oa":false,"landing_page_url":"http://simg.it/documenti/aree_cliniche/cardiovascolare/bibliografiche/abstracts/abstract278.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1136/bmj.38226.719803.eb","doi":"https://doi.org/10.1136/bmj.38226.719803.eb","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.38226.719803.eb","pdf_url":"https://www.bmj.com/content/bmj/329/7470/821.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4732215430","display_name":null,"funder_award_id":"1 D55 HP 00232","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"}],"funders":[{"id":"https://openalex.org/F4320332175","display_name":"Health Resources and Services Administration","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139088247.pdf","grobid_xml":"https://content.openalex.org/works/W2139088247.grobid-xml"},"referenced_works_count":116,"referenced_works":["https://openalex.org/W40543357","https://openalex.org/W42362463","https://openalex.org/W59414026","https://openalex.org/W94157919","https://openalex.org/W198297374","https://openalex.org/W302987128","https://openalex.org/W1550291796","https://openalex.org/W1588313728","https://openalex.org/W1830421708","https://openalex.org/W1960766055","https://openalex.org/W1967670934","https://openalex.org/W1968809611","https://openalex.org/W1969069179","https://openalex.org/W1970598617","https://openalex.org/W1972271794","https://openalex.org/W1979421845","https://openalex.org/W1980599553","https://openalex.org/W1980608787","https://openalex.org/W1981703712","https://openalex.org/W1982088978","https://openalex.org/W1986179297","https://openalex.org/W1987314584","https://openalex.org/W1991358497","https://openalex.org/W1991725975","https://openalex.org/W1995133719","https://openalex.org/W1996985850","https://openalex.org/W1999640788","https://openalex.org/W2003149127","https://openalex.org/W2005134939","https://openalex.org/W2005796654","https://openalex.org/W2005903777","https://openalex.org/W2008265412","https://openalex.org/W2009539365","https://openalex.org/W2015195924","https://openalex.org/W2018244933","https://openalex.org/W2023320322","https://openalex.org/W2025802509","https://openalex.org/W2026760952","https://openalex.org/W2029221456","https://openalex.org/W2030076986","https://openalex.org/W2031457501","https://openalex.org/W2032420239","https://openalex.org/W2034322821","https://openalex.org/W2042458901","https://openalex.org/W2042837418","https://openalex.org/W2043251359","https://openalex.org/W2044629262","https://openalex.org/W2048512219","https://openalex.org/W2050891137","https://openalex.org/W2052303494","https://openalex.org/W2053500608","https://openalex.org/W2054118780","https://openalex.org/W2057631921","https://openalex.org/W2058771258","https://openalex.org/W2059207971","https://openalex.org/W2060633743","https://openalex.org/W2060723099","https://openalex.org/W2060731708","https://openalex.org/W2064915821","https://openalex.org/W2065379041","https://openalex.org/W2065665685","https://openalex.org/W2066382762","https://openalex.org/W2067437176","https://openalex.org/W2069767988","https://openalex.org/W2074075430","https://openalex.org/W2085995021","https://openalex.org/W2088909125","https://openalex.org/W2093139979","https://openalex.org/W2096101262","https://openalex.org/W2096751776","https://openalex.org/W2097560918","https://openalex.org/W2097851766","https://openalex.org/W2098105118","https://openalex.org/W2105415279","https://openalex.org/W2110449079","https://openalex.org/W2118345547","https://openalex.org/W2119844925","https://openalex.org/W2125326171","https://openalex.org/W2125569585","https://openalex.org/W2125981586","https://openalex.org/W2126646660","https://openalex.org/W2129198157","https://openalex.org/W2132497978","https://openalex.org/W2138218664","https://openalex.org/W2141850575","https://openalex.org/W2142656693","https://openalex.org/W2147759117","https://openalex.org/W2150121055","https://openalex.org/W2150290224","https://openalex.org/W2154704891","https://openalex.org/W2159099657","https://openalex.org/W2166615708","https://openalex.org/W2167584157","https://openalex.org/W2167728254","https://openalex.org/W2265975124","https://openalex.org/W2297304314","https://openalex.org/W2298593123","https://openalex.org/W2322329123","https://openalex.org/W2324873593","https://openalex.org/W2329819604","https://openalex.org/W2398248869","https://openalex.org/W2400435785","https://openalex.org/W2400620110","https://openalex.org/W2405047845","https://openalex.org/W2405528463","https://openalex.org/W2410863003","https://openalex.org/W2412880945","https://openalex.org/W2414008451","https://openalex.org/W2415741583","https://openalex.org/W2421843463","https://openalex.org/W2623512411","https://openalex.org/W4251164421","https://openalex.org/W4300718545","https://openalex.org/W4324262536","https://openalex.org/W4366064926","https://openalex.org/W6700731416"],"related_works":["https://openalex.org/W2006001342","https://openalex.org/W2373281253","https://openalex.org/W2060731708","https://openalex.org/W2125981586","https://openalex.org/W1991725975","https://openalex.org/W2034322821","https://openalex.org/W2088998968","https://openalex.org/W2186270180","https://openalex.org/W2065665685","https://openalex.org/W2354393728"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"summarise":[2],"the":[3,6,20,36,94,139,147,185,230],"evidence":[4],"supporting":[5],"use":[7],"of":[8,15,22,38,46,89,93,116,151,169,189,205,217,238,268],"rapid":[9,72],"d-dimer":[10],"testing":[11],"combined":[12],"with":[13,164,199],"estimation":[14],"clinical":[16,87,167,203,219,266],"probability":[17,88,168,204,220,267],"to":[18,33,78,110,160,195],"exclude":[19],"diagnosis":[21,237],"deep":[23,90,170,206,222,254,269],"venous":[24,124,152,190,240],"thrombosis":[25,92,172,208,224,241,256],"among":[26,58,97,162,197,257],"outpatients.":[27,99],"DATA":[28],"SOURCES:":[29],"Medline":[30],"(June":[31],"1993":[32],"December":[34],"2003),":[35],"Database":[37],"Abstracts":[39],"and":[40,43,69,75,106,173,209,225],"Reviews":[41],"(DARE),":[42],"reference":[44],"lists":[45],"studies":[47,56,63],"in":[48],"English.":[49],"SELECTION":[50],"OF":[51],"STUDIES:":[52],"We":[53],"selected":[54,62],"12":[55],"from":[57,229,245],"84":[59],"reviewed.":[60],"The":[61,119,215],"included":[64],"more":[65],"than":[66],"5000":[67],"patients":[68,108,163,258],"used":[70,146],"a":[71,133,165,178,210,226,236,246],"D-dimer":[73,143,175,181,212,232,249],"assay":[74,144,182],"explicit":[76],"criteria":[77],"classify":[79],"cases":[80],"as":[81,260],"having":[82,261],"low,":[83],"intermediate,":[84],"or":[85,201,264],"high":[86],"vein":[91,171,207,223,255,270],"lower":[95],"extremity":[96],"consecutive":[98],"REVIEW":[100],"METHODS:":[101],"Diagnosis":[102],"required":[103],"objective":[104],"confirmation,":[105],"untreated":[107],"had":[109],"have":[111],"at":[112],"least":[113],"three":[114,148,186],"months":[115],"follow":[117],"up.":[118],"outcome":[120],"was":[121,145,154,183,192],"objectively":[122],"documented":[123],"thromboembolism.":[125],"Two":[126],"authors":[127],"independently":[128],"abstracted":[129],"data":[130,134],"by":[131],"using":[132],"collection":[135],"form.":[136],"RESULTS:":[137],"When":[138,177],"less":[140],"sensitive":[141,180,248],"SimpliRED":[142,231],"month":[149,187],"incidence":[150,188],"thromboembolism":[153,191],"0.5%":[155],"(95%":[156],"confidence":[157],"interval":[158],"0.07%":[159],"1.1%)":[161,196],"low":[166,200,218,263],"normal":[174,211,227,243],"concentrations.":[176],"highly":[179,247],"used,":[184],"0.4%":[193],"(0.04%":[194],"outpatients":[198],"moderate":[202,265],"concentration.":[213],"CONCLUSIONS:":[214],"combination":[216],"for":[221],"result":[228,244],"test":[233,250],"safely":[234],"excludes":[235],"acute":[239],"A":[242],"effectively":[251],"rules":[252],"out":[253],"classified":[259],"either":[262],"thrombosis.":[271]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}