{"id":"https://openalex.org/W2139083124","doi":"https://doi.org/10.1155/2013/983149","title":"Cockroach Allergen Bla g 7 Promotes TIM4 Expression in Dendritic Cells Leading to Th2 Polarization","display_name":"Cockroach Allergen Bla g 7 Promotes TIM4 Expression in Dendritic Cells Leading to Th2 Polarization","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2139083124","doi":"https://doi.org/10.1155/2013/983149","mag":"2139083124","pmid":"https://pubmed.ncbi.nlm.nih.gov/24204099","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3800592"},"language":"en","primary_location":{"id":"doi:10.1155/2013/983149","doi":"https://doi.org/10.1155/2013/983149","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2013/983149","pdf_url":"https://downloads.hindawi.com/journals/mi/2013/983149.pdf","source":{"id":"https://openalex.org/S107442880","display_name":"Mediators of Inflammation","issn_l":"0962-9351","issn":["0962-9351","1466-1861"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mediators of Inflammation","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2139083124"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://downloads.hindawi.com/journals/mi/2013/983149.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035203650","display_name":"Lingxiao Xu","orcid":"https://orcid.org/0000-0003-3418-0727","observed_orcids":["https://orcid.org/0000-0003-3418-0727"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingxiao Xu","raw_affiliation_strings":["Clinical Research Centre, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China","Department of Rheumatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Centre, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China","institution_ids":["https://openalex.org/I4210152119"]},{"raw_affiliation_string":"Department of Rheumatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102931886","display_name":"Miaojia Zhang","orcid":"https://orcid.org/0000-0003-4535-7743","observed_orcids":["https://orcid.org/0000-0003-4535-7743"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Miaojia Zhang","raw_affiliation_strings":["Department of Rheumatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wenjing Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenjing Ma","raw_affiliation_strings":["Clinical Research Centre, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Centre, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057544308","display_name":"Shanshan Jin","orcid":"https://orcid.org/0000-0002-6839-4021","observed_orcids":["https://orcid.org/0000-0002-6839-4021"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shanshan Jin","raw_affiliation_strings":["Clinical Research Centre, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Centre, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014758525","display_name":"Weijuan Song","orcid":"https://orcid.org/0000-0001-6439-1563","observed_orcids":["https://orcid.org/0000-0001-6439-1563"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weijuan Song","raw_affiliation_strings":["Clinical Research Centre, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Centre, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101901537","display_name":"Shaoheng He","orcid":"https://orcid.org/0000-0002-4230-7639","observed_orcids":["https://orcid.org/0000-0002-4230-7639"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shaoheng He","raw_affiliation_strings":["Clinical Research Centre, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Centre, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5101901537"],"corresponding_institution_ids":["https://openalex.org/I4210152119"],"apc_list":{"value":3040,"currency":"USD","value_usd":3040},"apc_paid":{"value":3040,"currency":"USD","value_usd":3040},"fwci":1.0099,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.74731903,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"2013","issue":null,"first_page":"1","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9696999788284302,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9696999788284302,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.018200000748038292,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blattella-germanica","display_name":"Blattella germanica","score":0.9760000109672546},{"id":"https://openalex.org/keywords/tim-4","display_name":"TIM-4","score":0.7570000290870667},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.8190000057220459},{"id":"https://openalex.org/keywords/th2-polarization","display_name":"Th2 polarization","score":0.9649999737739563},{"id":"https://openalex.org/keywords/th1-th2-balance","display_name":"Th1/Th2 balance","score":0.8429999947547913},{"id":"https://openalex.org/keywords/il-13","display_name":"IL-13","score":0.9369999766349792},{"id":"https://openalex.org/keywords/cd80","display_name":"CD80","score":0.8460000157356262},{"id":"https://openalex.org/keywords/cd86","display_name":"CD86","score":1.0},{"id":"https://openalex.org/keywords/cd4-t-cells","display_name":"CD4+ T cells","score":0.8159999847412109},{"id":"https://openalex.org/keywords/cockroach-allergy","display_name":"cockroach allergy","score":0.6949999928474426},{"id":"https://openalex.org/keywords/allergic-rhinitis","display_name":"allergic rhinitis","score":0.8339999914169312},{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.8560000061988831}],"concepts":[{"id":"https://openalex.org/C2781101188","wikidata":"https://www.wikidata.org/wiki/Q5009846","display_name":"CD86","level":4,"score":0.8621729612350464},{"id":"https://openalex.org/C2778297628","wikidata":"https://www.wikidata.org/wiki/Q5009843","display_name":"CD80","level":5,"score":0.8491131067276001},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5613545179367065},{"id":"https://openalex.org/C2777346155","wikidata":"https://www.wikidata.org/wiki/Q18123008","display_name":"Cockroach","level":2,"score":0.5172513127326965},{"id":"https://openalex.org/C191732599","wikidata":"https://www.wikidata.org/wiki/Q14865947","display_name":"Interleukin 4","level":3,"score":0.4679739773273468},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41926059126853943},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.33502084016799927},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.32697033882141113},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.28603777289390564},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.28121453523635864},{"id":"https://openalex.org/C39347974","wikidata":"https://www.wikidata.org/wiki/Q21135811","display_name":"CD40","level":4,"score":0.2527567148208618},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.2493058741092682},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.17843550443649292},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.05806499719619751},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007963","descriptor_name":"Leukocytes, Mononuclear","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007963","descriptor_name":"Leukocytes, Mononuclear","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014335","descriptor_name":"Tropomyosin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015847","descriptor_name":"Interleukin-4","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018122","descriptor_name":"B7-1 Antigen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018418","descriptor_name":"Th2 Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018793","descriptor_name":"Interleukin-13","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018920","descriptor_name":"Coculture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051940","descriptor_name":"B7-2 Antigen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1155/2013/983149","doi":"https://doi.org/10.1155/2013/983149","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2013/983149","pdf_url":"https://downloads.hindawi.com/journals/mi/2013/983149.pdf","source":{"id":"https://openalex.org/S107442880","display_name":"Mediators of Inflammation","issn_l":"0962-9351","issn":["0962-9351","1466-1861"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mediators of Inflammation","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2808807","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3800592","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:24204099","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24204099","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mediators of inflammation","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3800592","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3800592/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mediators Inflamm","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:d39cf8199040489fa8203f905e1530fd","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/d39cf8199040489fa8203f905e1530fd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Mediators of Inflammation, Vol 2013 (2013)","raw_type":"article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.772.5782","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.772.5782","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/d7/a2/MI2013-983149.PMC3800592.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1155/2013/983149","doi":"https://doi.org/10.1155/2013/983149","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2013/983149","pdf_url":"https://downloads.hindawi.com/journals/mi/2013/983149.pdf","source":{"id":"https://openalex.org/S107442880","display_name":"Mediators of Inflammation","issn_l":"0962-9351","issn":["0962-9351","1466-1861"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mediators of Inflammation","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1148399346","display_name":null,"funder_award_id":"BK2010020","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1683310591","display_name":null,"funder_award_id":"XK201115","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1828425977","display_name":null,"funder_award_id":"973 Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3408496755","display_name":null,"funder_award_id":"2013CB530500","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6235205277","display_name":null,"funder_award_id":"2013CB530500","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G7399822527","display_name":null,"funder_award_id":"81172836","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8937349964","display_name":"\u6c34\u901a\u9053\u86cb\u767d4\u5f71\u54cd\u6291\u90c1\u75c7\u53d1\u751f\u53d1\u5c55\u7684\u673a\u5236\u7814\u7a76","funder_award_id":"81001427","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321605","display_name":"Government of Jiangsu Province","ror":"https://ror.org/004svx814"},{"id":"https://openalex.org/F4320327518","display_name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139083124.pdf","grobid_xml":"https://content.openalex.org/works/W2139083124.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W48276361","https://openalex.org/W289046778","https://openalex.org/W1507248048","https://openalex.org/W1528203757","https://openalex.org/W1531317003","https://openalex.org/W1558405203","https://openalex.org/W1588998018","https://openalex.org/W1650170846","https://openalex.org/W1676258780","https://openalex.org/W1908511571","https://openalex.org/W1977067868","https://openalex.org/W1986901530","https://openalex.org/W2011064526","https://openalex.org/W2012341843","https://openalex.org/W2013883532","https://openalex.org/W2016970487","https://openalex.org/W2017833871","https://openalex.org/W2021497228","https://openalex.org/W2046512238","https://openalex.org/W2051447573","https://openalex.org/W2051934098","https://openalex.org/W2054325242","https://openalex.org/W2060315709","https://openalex.org/W2065937821","https://openalex.org/W2068555248","https://openalex.org/W2076261439","https://openalex.org/W2079231364","https://openalex.org/W2080905450","https://openalex.org/W2087166273","https://openalex.org/W2087350627","https://openalex.org/W2095637502","https://openalex.org/W2119162416","https://openalex.org/W2123982765","https://openalex.org/W2124554987","https://openalex.org/W2145614866","https://openalex.org/W2163234342","https://openalex.org/W2171230685","https://openalex.org/W2394827238","https://openalex.org/W2403648683","https://openalex.org/W2416705559","https://openalex.org/W4255815190"],"related_works":["https://openalex.org/W338374543","https://openalex.org/W2336482201","https://openalex.org/W2102224236","https://openalex.org/W2020877535","https://openalex.org/W1927089433","https://openalex.org/W2076261439","https://openalex.org/W1993333012","https://openalex.org/W2163234342"],"abstract_inverted_index":{"As":[0],"one":[1],"of":[2,7,39,46,85,104,108,130,171,178,185],"the":[3,20,37,44,102,128,135,145,164,176],"most":[4],"common":[5],"sources":[6],"indoor":[8],"aeroallergens":[9],"worldwide,":[10],"cockroach":[11,179,190],"is":[12,61,155],"important":[13,34],"in":[14,36,175,189],"causing":[15],"rhinitis":[16],"and":[17,88,90,125,133,159,181],"asthma":[18],"while":[19],"mechanisms":[21],"underlying":[22],"remain":[23],"obscure.":[24],"Since":[25],"T":[26,97,110],"helper":[27],"(Th)":[28],"type":[29],"2":[30],"polarization":[31,59,147,188],"plays":[32],"an":[33,183],"role":[35,170],"pathogenesis":[38],"allergic":[40],"diseases,":[41],"we":[42],"investigated":[43],"effect":[45],"Bla":[47,71,172],"g":[48,72,75,141,151,173],"7,":[49,142],"a":[50,113,168],"pan-allergen":[51],"from":[52,80,116],"Blattella":[53],"germanica":[54],"(B.":[55],"germanica),":[56],"on":[57],"Th":[58],"which":[60],"controlled":[62],"by":[63,69,139,149],"monocyte-derived":[64],"dendritic":[65],"cells":[66],"(DCs).":[67],"Challenged":[68],"recombinant":[70],"7":[73,152,174],"(rBla":[74],"7),":[76],"immature":[77],"DCs":[78,100,154],"obtained":[79],"human":[81],"exhibited":[82],"upregulated":[83],"levels":[84],"TIM4,":[86,123],"CD80,":[87,124],"CD86":[89,126],"increased":[91,101],"IL-13":[92,136],"secretion.":[93],"Cocultured":[94],"with":[95],"CD4+":[96,109],"cells,":[98,111],"challenged":[99,153],"ratio":[103,132],"IL-4+":[105],"versus":[106],"IFN-\u03b3+":[107],"suggesting":[112],"balance":[114],"shift":[115],"Th1":[117],"to":[118],"Th2.":[119],"Moreover,":[120],"antibodies":[121],"against":[122],"reversed":[127],"enhancement":[129],"IL-4+/IFN-\u03b3+":[131],"alleviated":[134],"release":[137],"induced":[138],"rBla":[140,150],"indicating":[143],"that":[144],"Th2":[146,187],"provoked":[148],"via":[156],"TIM4-,":[157],"CD80-,":[158],"CD86-dependent":[160],"mechanisms.":[161],"In":[162],"conclusion,":[163],"present":[165],"findings":[166],"implied":[167],"crucial":[169],"development":[177],"allergy":[180],"highlighted":[182],"involvement":[184],"DCs-induced":[186],"allergy.":[191]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-15T12:55:33.944570","created_date":"2016-06-24T00:00:00"}