{"id":"https://openalex.org/W2139081852","doi":"https://doi.org/10.1080/10739680601139237","title":"Computational Network Model Prediction of Hemodynamic Alterations Due to Arteriolar Remodeling in Interval Sprint Trained Skeletal Muscle","display_name":"Computational Network Model Prediction of Hemodynamic Alterations Due to Arteriolar Remodeling in Interval Sprint Trained Skeletal Muscle","publication_year":2007,"publication_date":"2007-03-04","ids":{"openalex":"https://openalex.org/W2139081852","doi":"https://doi.org/10.1080/10739680601139237","mag":"2139081852","pmid":"https://pubmed.ncbi.nlm.nih.gov/17454671"},"language":"en","primary_location":{"id":"doi:10.1080/10739680601139237","doi":"https://doi.org/10.1080/10739680601139237","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10739680601139237","pdf_url":null,"source":{"id":"https://openalex.org/S111876535","display_name":"Microcirculation","issn_l":"1073-9688","issn":["1073-9688","1549-8719"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microcirculation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046471014","display_name":"Kyle W. Binder","orcid":"https://orcid.org/0000-0001-6605-1992","observed_orcids":["https://orcid.org/0000-0001-6605-1992"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyle W. Binder","raw_affiliation_strings":["Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22908, USA","Department of Biomedical Engineering, University of Virginia Charlottesville Virginia USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22908, USA","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Virginia Charlottesville Virginia USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079924666","display_name":"Walter Lee Murfee","orcid":"https://orcid.org/0000-0002-8247-4722","observed_orcids":["https://orcid.org/0000-0002-8247-4722"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Walter L. Murfee","raw_affiliation_strings":["Department of Biomedical Engineering, University of California at San Diego, La Jolla, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of California at San Diego, La Jolla, California, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103394191","display_name":"Ji Sun Song","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ji Song","raw_affiliation_strings":["Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA","Department of Biomedical Engineering, University of Virginia Charlottesville Virginia USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Virginia Charlottesville Virginia USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110291995","display_name":"M. Harold Laughlin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Harold Laughlin","raw_affiliation_strings":["Department of Veterinary Biomedical Sciences, University of Missouri, Columbia, Missouri, USA","Department of Veterinary Biomedical Sciences, University of  Missouri, Columbia, Missouri, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Biomedical Sciences, University of Missouri, Columbia, Missouri, USA","institution_ids":["https://openalex.org/I76835614"]},{"raw_affiliation_string":"Department of Veterinary Biomedical Sciences, University of  Missouri, Columbia, Missouri, USA","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053168739","display_name":"Richard J. Price","orcid":"https://orcid.org/0000-0002-0237-2102","observed_orcids":["https://orcid.org/0000-0002-0237-2102"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Richard J. Price","raw_affiliation_strings":["Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA","Department of Biomedical Engineering, University of Virginia Charlottesville Virginia USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Virginia Charlottesville Virginia USA","institution_ids":["https://openalex.org/I51556381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5053168739"],"corresponding_institution_ids":["https://openalex.org/I51556381"],"apc_list":{"value":3920,"currency":"USD","value_usd":3920},"apc_paid":null,"fwci":6.4311,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.95191882,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"14","issue":"3","first_page":"181","last_page":"192"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-intensity-interval-training","display_name":"high-intensity interval training","score":0.9259999990463257},{"id":"https://openalex.org/keywords/arteriolar-remodeling","display_name":"arteriolar remodeling","score":0.9480000138282776},{"id":"https://openalex.org/keywords/skeletal-muscle-microcirculation","display_name":"skeletal muscle microcirculation","score":0.7799999713897705},{"id":"https://openalex.org/keywords/gastrocnemius-muscle","display_name":"gastrocnemius","score":0.7450000047683716},{"id":"https://openalex.org/keywords/red-blood-cell-distribution","display_name":"red blood cell distribution","score":0.6809999942779541},{"id":"https://openalex.org/keywords/hematocrit","display_name":"hematocrit","score":0.8709999918937683},{"id":"https://openalex.org/keywords/apparent-viscosity","display_name":"apparent viscosity","score":0.7739999890327454},{"id":"https://openalex.org/keywords/pressure-drop-distribution","display_name":"pressure drop distribution","score":0.550000011920929},{"id":"https://openalex.org/keywords/fast-twitch-glycolytic-fibers","display_name":"fast-twitch glycolytic fibers","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C126707884","wikidata":"https://www.wikidata.org/wiki/Q305876","display_name":"sed","level":2,"score":0.732982873916626},{"id":"https://openalex.org/C2776868573","wikidata":"https://www.wikidata.org/wiki/Q46855","display_name":"Sprint","level":2,"score":0.7059986591339111},{"id":"https://openalex.org/C2779482390","wikidata":"https://www.wikidata.org/wiki/Q501908","display_name":"Arteriole","level":3,"score":0.6980370283126831},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.6894693374633789},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.5757927894592285},{"id":"https://openalex.org/C2780959883","wikidata":"https://www.wikidata.org/wiki/Q111146","display_name":"Hematocrit","level":2,"score":0.5342935919761658},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.46828076243400574},{"id":"https://openalex.org/C12722491","wikidata":"https://www.wikidata.org/wiki/Q1632335","display_name":"Microcirculation","level":2,"score":0.43692609667778015},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4367036819458008},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.42441967129707336},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4121946096420288},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.386797159910202},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36671799421310425},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.18861383199691772}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008833","descriptor_name":"Microcirculation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008833","descriptor_name":"Microcirculation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008833","descriptor_name":"Microcirculation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008833","descriptor_name":"Microcirculation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008833","descriptor_name":"Microcirculation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010805","descriptor_name":"Physical Conditioning, Animal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010805","descriptor_name":"Physical Conditioning, Animal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010805","descriptor_name":"Physical Conditioning, Animal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010805","descriptor_name":"Physical Conditioning, Animal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010805","descriptor_name":"Physical Conditioning, Animal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018656","descriptor_name":"Muscle Fibers, Fast-Twitch","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018656","descriptor_name":"Muscle Fibers, Fast-Twitch","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018656","descriptor_name":"Muscle Fibers, Fast-Twitch","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018656","descriptor_name":"Muscle Fibers, Fast-Twitch","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018656","descriptor_name":"Muscle Fibers, Fast-Twitch","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1080/10739680601139237","doi":"https://doi.org/10.1080/10739680601139237","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10739680601139237","pdf_url":null,"source":{"id":"https://openalex.org/S111876535","display_name":"Microcirculation","issn_l":"1073-9688","issn":["1073-9688","1549-8719"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microcirculation","raw_type":"journal-article"},{"id":"pmid:17454671","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17454671","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microcirculation (New York, N.Y. : 1994)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6100000143051147}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1398882299","display_name":null,"funder_award_id":"HL-65958","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1707848829","display_name":null,"funder_award_id":"HL30688","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6806639204","display_name":null,"funder_award_id":"R01 HL066037","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7965740727","display_name":null,"funder_award_id":"HL66037","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8235219624","display_name":"Integrated Control of Vascular Pattern Formation","funder_award_id":"R01HL065958","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8259420954","display_name":"Training-Muscle Blood Flow and Capillary Dynamics","funder_award_id":"R01HL036088","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W39210669","https://openalex.org/W954944586","https://openalex.org/W1797533920","https://openalex.org/W1838550520","https://openalex.org/W1899819734","https://openalex.org/W1933701962","https://openalex.org/W1982366405","https://openalex.org/W1988957088","https://openalex.org/W2019000864","https://openalex.org/W2031644578","https://openalex.org/W2053192704","https://openalex.org/W2053484199","https://openalex.org/W2079072735","https://openalex.org/W2092570173","https://openalex.org/W2093013567","https://openalex.org/W2105437420","https://openalex.org/W2107621770","https://openalex.org/W2108322208","https://openalex.org/W2120757978","https://openalex.org/W2126410943","https://openalex.org/W2129689780","https://openalex.org/W2136386328","https://openalex.org/W2145166689","https://openalex.org/W2171980151","https://openalex.org/W2205260534","https://openalex.org/W2281769616","https://openalex.org/W2307876399","https://openalex.org/W2401899500","https://openalex.org/W2411888037","https://openalex.org/W2414858881","https://openalex.org/W2464836059"],"related_works":["https://openalex.org/W2372214266","https://openalex.org/W263489676","https://openalex.org/W4211104393","https://openalex.org/W4205734662","https://openalex.org/W2181820438","https://openalex.org/W2370895232","https://openalex.org/W166342633","https://openalex.org/W2358670732","https://openalex.org/W2361349236","https://openalex.org/W2030036148"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Exercise":[1],"training":[2,16,99],"is":[3,236],"known":[4],"to":[5,36,49,120,146,202,216,234],"enhance":[6],"skeletal":[7],"muscle":[8],"blood":[9,133],"flow":[10,51,208,255],"capacity,":[11],"with":[12,21,173],"high-intensity":[13],"interval":[14],"sprint":[15],"(IST)":[17],"primarily":[18],"affecting":[19],"muscles":[20,79],"a":[22,122,151,179,222,258],"high":[23,262],"proportion":[24],"of":[25,32,41,56,77,80,84,124,185,192,225,254,261],"fast":[26],"twitch":[27],"glycolytic":[28],"fibers.":[29],"The":[30,68,231],"objective":[31],"this":[33],"study":[34],"was":[35,228],"determine":[37],"the":[38,54,65,74,157,168,183,186,190,193,197,200,203,242,265],"relative":[39],"contributions":[40],"new":[42],"arteriole":[43],"formation":[44],"and":[45,53,104,114,136,138,164,205,207,257],"lumenal":[46],"arteriolar":[47,71,266],"remodeling":[48],"enhanced":[50],"capacity":[52,209,256],"impact":[55],"these":[57],"adaptations":[58],"on":[59],"local":[60],"microvascular":[61],"hemodynamics":[62],"deep":[63],"within":[64],"muscle.":[66],"METHODS:":[67],"authors":[69],"studied":[70],"adaptation":[72,233],"in":[73,154,156,174,178,214,219,239,241,248],"white/mixed-fiber":[75],"portion":[76],"gastrocnemius":[78],"IST":[81,149,163,188,220,235],"(6":[82],"bouts":[83],"running/day;":[85],"2.5":[86],"min/bout;":[87],"60":[88],"m/min":[89],"speed;":[90],"15%":[91],"grade;":[92],"4.5":[93],"min":[94],"rest":[95],"between":[96],"bouts;":[97],"5":[98],"days/wk;":[100],"10":[101],"wks":[102],"total)":[103],"sedentary":[105],"(SED)":[106],"control":[107],"rats":[108],"using":[109],"whole-muscle":[110],"Microfil":[111],"casts.":[112],"Dimensional":[113],"topological":[115],"data":[116],"were":[117],"then":[118],"used":[119],"construct":[121],"series":[123],"computational":[125],"hemodynamic":[126],"network":[127,198],"models":[128],"that":[129],"incorporated":[130],"physiological":[131],"red":[132],"cell":[134],"distributions":[135],"hematocrit":[137],"diameter":[139],"dependent":[140],"apparent":[141],"viscosities.":[142],"RESULTS:":[143],"In":[144],"comparison":[145],"SED":[147,165,215],"controls,":[148],"elicited":[150],"significant":[152],"increase":[153,238],"arterioles/order":[155],"3A":[158,243],"through":[159,167,244],"6A":[160,245],"generations.":[161],"Predicted":[162],"flows":[166],"2A":[169],"generation":[170],"agreed":[171],"closely":[172],"vivo":[175],"measurements":[176],"made":[177],"previous":[180],"study,":[181],"illustrating":[182],"accuracy":[184],"model.":[187],"shifted":[189],"bulk":[191],"pressure":[194,224,263],"drop":[195],"across":[196],"from":[199,211],"3As":[201],"4As":[204],"5As,":[206],"increased":[210],"0.7":[212],"mL/min":[213,218],"1.5":[217],"when":[221],"driving":[223],"80":[226],"mmHg":[227],"applied.":[229],"CONCLUSIONS:":[230],"primary":[232],"an":[237,251],"arterioles":[240],"generations,":[246],"which,":[247],"turn,":[249],"creates":[250],"approximate":[252],"doubling":[253],"deeper":[259],"penetration":[260],"into":[264],"network.":[267]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-15T10:00:46.086208","created_date":"2025-10-10T00:00:00"}