{"id":"https://openalex.org/W2139031901","doi":null,"title":"Bipolar disorder and alcoholism","display_name":"Bipolar disorder and alcoholism","publication_year":2002,"publication_date":"2002-03-22","ids":{"openalex":"https://openalex.org/W2139031901","mag":"2139031901"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:5637189","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6683827","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6683827","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056814683","display_name":"Susan C. Sonne","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susan C. Sonne","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5036627459","display_name":"Kathleen T. Brady","orcid":"https://orcid.org/0000-0002-3944-8051","observed_orcids":["https://orcid.org/0000-0002-3944-8051","https://orcid.org/0000-0002-5963-2294"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathleen T. Brady","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3944-8051","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3656,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.60581378,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"26","issue":"2","first_page":"103","last_page":"109"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11093","display_name":"Personality Disorders and Psychopathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bipolar-disorder","display_name":"bipolar disorder","score":1.0},{"id":"https://openalex.org/keywords/alcoholism","display_name":"alcoholism","score":0.9599999785423279},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.8510000109672546},{"id":"https://openalex.org/keywords/genetic-link","display_name":"genetic link","score":0.8230000138282776},{"id":"https://openalex.org/keywords/valproic-acid","display_name":"valproic acid","score":0.996999979019165},{"id":"https://openalex.org/keywords/lithium","display_name":"lithium","score":1.0},{"id":"https://openalex.org/keywords/naltrexone","display_name":"naltrexone","score":1.0},{"id":"https://openalex.org/keywords/psychosocial-interventions","display_name":"psychosocial interventions","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C2776174506","wikidata":"https://www.wikidata.org/wiki/Q131755","display_name":"Bipolar disorder","level":3,"score":0.792597234249115},{"id":"https://openalex.org/C2777972943","wikidata":"https://www.wikidata.org/wiki/Q409587","display_name":"Naltrexone","level":4,"score":0.7872521877288818},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.7355347871780396},{"id":"https://openalex.org/C150966472","wikidata":"https://www.wikidata.org/wiki/Q3410145","display_name":"Psychosocial","level":2,"score":0.5927467346191406},{"id":"https://openalex.org/C2778541603","wikidata":"https://www.wikidata.org/wiki/Q152763","display_name":"Lithium (medication)","level":2,"score":0.5919432640075684},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5743616819381714},{"id":"https://openalex.org/C2779442783","wikidata":"https://www.wikidata.org/wiki/Q15326","display_name":"Alcohol use disorder","level":3,"score":0.513153612613678},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.44758808612823486},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.42837607860565186},{"id":"https://openalex.org/C2779436514","wikidata":"https://www.wikidata.org/wiki/Q4713263","display_name":"Alcohol dependence","level":3,"score":0.41995736956596375},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4068288505077362},{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.23548656702041626},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15680921077728271},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:5637189","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6683827","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6683827","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6683827/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcohol Res Health","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.626.4894","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.626.4894","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://pubs.niaaa.nih.gov/publications/arh26-2/103-108.pdf","raw_type":"text"},{"id":"mag:2139031901","doi":null,"is_oa":false,"landing_page_url":"http://pubs.niaaa.nih.gov/publications/arh26-2/103-108.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S20790815","display_name":"Alcohol Research & Health","issn_l":"1535-7414","issn":["1535-7414"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","poland-140"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Alcohol Research & Health","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5637189","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6683827","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.9907000064849854,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W161993100","https://openalex.org/W311219321","https://openalex.org/W1709742262","https://openalex.org/W1778494765","https://openalex.org/W1964331390","https://openalex.org/W1975673736","https://openalex.org/W2002183828","https://openalex.org/W2011709753","https://openalex.org/W2028878833","https://openalex.org/W2032931662","https://openalex.org/W2054484585","https://openalex.org/W2054572750","https://openalex.org/W2056500109","https://openalex.org/W2057185756","https://openalex.org/W2057620448","https://openalex.org/W2058704610","https://openalex.org/W2093604958","https://openalex.org/W2107242691","https://openalex.org/W2117685669","https://openalex.org/W2121477985","https://openalex.org/W2121585495","https://openalex.org/W2130582087","https://openalex.org/W2150442469","https://openalex.org/W2168025883","https://openalex.org/W2283141188","https://openalex.org/W2329642814","https://openalex.org/W2337861388","https://openalex.org/W2416327122","https://openalex.org/W4247496126"],"related_works":["https://openalex.org/W2103206008","https://openalex.org/W2002476212","https://openalex.org/W3138600251","https://openalex.org/W2943121075","https://openalex.org/W3028650400","https://openalex.org/W2071883011","https://openalex.org/W4392711373","https://openalex.org/W5236900","https://openalex.org/W2507707333","https://openalex.org/W2040712588"],"abstract_inverted_index":{"Bipolar":[0,124],"disorder":[1,125],"and":[2,36,74,98,126,146,154],"alcoholism":[3,127,153],"commonly":[4],"co-occur.":[5],"Multiple":[6],"explanations":[7],"for":[8,34,62],"the":[9,42,59,69,161],"relationship":[10,19,162],"between":[11],"these":[12],"conditions":[13],"have":[14,67],"been":[15,55],"proposed,":[16],"but":[17,86],"this":[18],"remains":[20],"poorly":[21],"understood.":[22],"Some":[23,65],"evidence":[24],"suggests":[25],"a":[26],"genetic":[27,105],"link.":[28],"This":[29,157],"comorbidity":[30],"also":[31],"has":[32,54],"implications":[33],"diagnosis":[35],"treatment.":[37],"Alcohol":[38],"use":[39],"may":[40],"worsen":[41],"clinical":[43],"course":[44],"of":[45,71],"bipolar":[46,84],"disorder,":[47],"making":[48],"it":[49],"harder":[50],"to":[51],"treat.":[52],"There":[53],"little":[56],"research":[57,88],"on":[58],"appropriate":[60],"treatment":[61,120],"comorbid":[63],"patients.":[64],"studies":[66],"evaluated":[68],"effects":[70],"valproate,":[72],"lithium,":[73],"naltrexone,":[75],"as":[76,78],"well":[77],"psychosocial":[79,119],"interventions,":[80],"in":[81],"treating":[82],"alcoholic":[83,102],"patients,":[85],"further":[87],"is":[89],"needed.":[90],"KEY":[91],"WORDS:":[92],"comorbidity;":[93],"manic-depressive":[94],"psychosis;":[95],"AODD":[96],"(alcohol":[97],"other":[99],"drug":[100,112],"dependence);":[101],"beverage;":[103],"prevalence;":[104],"linkage;":[106],"disease":[107,109],"onset;":[108],"course;":[110],"diagnosis;":[111],"therapy;":[113],"lithium;":[114],"valproate;":[115],"naltrexone;":[116],"patient":[117],"compliance;":[118],"method;":[121],"literature":[122],"review":[123],"co-occur":[128,137,148],"at":[129],"higher":[130],"than":[131,140,151],"expected":[132,143],"rates.":[133],"That":[134],"is,":[135],"they":[136,147],"more":[138,149],"often":[139,150],"would":[141],"be":[142],"by":[144],"chance":[145],"do":[152],"unipolar":[155],"depression.":[156],"article":[158],"will":[159],"explore":[160]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}