{"id":"https://openalex.org/W2139013197","doi":"https://doi.org/10.1021/jp308938t","title":"Hyperspectral Imaging with Stimulated Raman Scattering by Chirped Femtosecond Lasers","display_name":"Hyperspectral Imaging with Stimulated Raman Scattering by Chirped Femtosecond Lasers","publication_year":2012,"publication_date":"2012-12-20","ids":{"openalex":"https://openalex.org/W2139013197","doi":"https://doi.org/10.1021/jp308938t","mag":"2139013197","pmid":"https://pubmed.ncbi.nlm.nih.gov/23256635"},"language":"en","primary_location":{"id":"doi:10.1021/jp308938t","doi":"https://doi.org/10.1021/jp308938t","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jp308938t","pdf_url":null,"source":{"id":"https://openalex.org/S185621672","display_name":"The Journal of Physical Chemistry B","issn_l":"1520-5207","issn":["1520-5207","1520-6106"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Physical Chemistry B","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3637845","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020132617","display_name":"Dan Fu","orcid":"https://orcid.org/0000-0001-9243-8306","observed_orcids":["https://orcid.org/0000-0001-9243-8306"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dan Fu","raw_affiliation_strings":["Department of Chemistry\rand\rChemical Biology, Harvard University, Cambridge,\rMassachusetts 02138, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry\rand\rChemical Biology, Harvard University, Cambridge,\rMassachusetts 02138, United States","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109228373","display_name":"Gary Holtom","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary Holtom","raw_affiliation_strings":["Department of Chemistry\rand\rChemical Biology, Harvard University, Cambridge,\rMassachusetts 02138, United States","Department of Chemistry#R#and#R#Chemical Biology, Harvard University, Cambridge,#R#Massachusetts 02138, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry\rand\rChemical Biology, Harvard University, Cambridge,\rMassachusetts 02138, United States","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Chemistry#R#and#R#Chemical Biology, Harvard University, Cambridge,#R#Massachusetts 02138, United States","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004406151","display_name":"Christian W. Freudiger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christian Freudiger","raw_affiliation_strings":["Department of Chemistry\rand\rChemical Biology, Harvard University, Cambridge,\rMassachusetts 02138, United States","Department of Chemistry#R#and#R#Chemical Biology, Harvard University, Cambridge,#R#Massachusetts 02138, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry\rand\rChemical Biology, Harvard University, Cambridge,\rMassachusetts 02138, United States","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Chemistry#R#and#R#Chemical Biology, Harvard University, Cambridge,#R#Massachusetts 02138, United States","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xu Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xu Zhang","raw_affiliation_strings":["Department of Chemistry\rand\rChemical Biology, Harvard University, Cambridge,\rMassachusetts 02138, United States","School of Engineering and Applied\rSciences, Harvard University, Cambridge,\rMassachusetts 02138, United States","School of Engineering and Applied#R#Sciences, Harvard University, Cambridge,#R#Massachusetts 02138, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry\rand\rChemical Biology, Harvard University, Cambridge,\rMassachusetts 02138, United States","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"School of Engineering and Applied\rSciences, Harvard University, Cambridge,\rMassachusetts 02138, United States","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"School of Engineering and Applied#R#Sciences, Harvard University, Cambridge,#R#Massachusetts 02138, United States","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102919090","display_name":"Xiaoliang Sunney Xie","orcid":"https://orcid.org/0000-0001-7714-9776","observed_orcids":["https://orcid.org/0000-0001-7714-9776"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Xiaoliang Sunney Xie","raw_affiliation_strings":["Department of Chemistry\rand\rChemical Biology, Harvard University, Cambridge,\rMassachusetts 02138, United States","Department of Chemistry#R#and#R#Chemical Biology, Harvard University, Cambridge,#R#Massachusetts 02138, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry\rand\rChemical Biology, Harvard University, Cambridge,\rMassachusetts 02138, United States","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Chemistry#R#and#R#Chemical Biology, Harvard University, Cambridge,#R#Massachusetts 02138, United States","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5102919090"],"corresponding_institution_ids":["https://openalex.org/I136199984"],"apc_list":null,"apc_paid":null,"fwci":7.3205,"has_fulltext":false,"cited_by_count":323,"citation_normalized_percentile":{"value":0.9840815,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"117","issue":"16","first_page":"4634","last_page":"4640"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10566","display_name":"Laser-Matter Interactions and Applications","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11177","display_name":"Spectroscopy and Quantum Chemical Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stimulated-raman-scattering-microscopy","display_name":"stimulated Raman scattering microscopy","score":0.8880000114440918},{"id":"https://openalex.org/keywords/hyperspectral-imaging","display_name":"hyperspectral imaging","score":0.9279999732971191},{"id":"https://openalex.org/keywords/spectral-focusing","display_name":"spectral focusing","score":0.8730000257492065},{"id":"https://openalex.org/keywords/label-free-chemical-imaging","display_name":"label-free chemical imaging","score":0.7710000276565552},{"id":"https://openalex.org/keywords/cholesterol-quantification","display_name":"cholesterol quantification","score":0.9039999842643738},{"id":"https://openalex.org/keywords/saturated-and-unsaturated-lipids","display_name":"saturated and unsaturated lipids","score":0.824999988079071},{"id":"https://openalex.org/keywords/lipid-distribution","display_name":"lipid distribution","score":0.4129999876022339},{"id":"https://openalex.org/keywords/protein-imaging","display_name":"protein imaging","score":0.48100000619888306}],"concepts":[{"id":"https://openalex.org/C159078339","wikidata":"https://www.wikidata.org/wiki/Q959005","display_name":"Hyperspectral imaging","level":2,"score":0.9359959363937378},{"id":"https://openalex.org/C65597285","wikidata":"https://www.wikidata.org/wiki/Q5090469","display_name":"Chemical imaging","level":3,"score":0.8241276741027832},{"id":"https://openalex.org/C167735695","wikidata":"https://www.wikidata.org/wiki/Q1777507","display_name":"Femtosecond","level":3,"score":0.7582355737686157},{"id":"https://openalex.org/C40003534","wikidata":"https://www.wikidata.org/wiki/Q862228","display_name":"Raman spectroscopy","level":2,"score":0.7525953054428101},{"id":"https://openalex.org/C169573571","wikidata":"https://www.wikidata.org/wiki/Q466824","display_name":"Raman scattering","level":3,"score":0.6885021924972534},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.6665139198303223},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.627967894077301},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5853567123413086},{"id":"https://openalex.org/C158479148","wikidata":"https://www.wikidata.org/wiki/Q609991","display_name":"Imaging spectroscopy","level":3,"score":0.5233646631240845},{"id":"https://openalex.org/C3232514","wikidata":"https://www.wikidata.org/wiki/Q7575196","display_name":"Spectral imaging","level":2,"score":0.5059012770652771},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.49976491928100586},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10475349426269531},{"id":"https://openalex.org/C62649853","wikidata":"https://www.wikidata.org/wiki/Q199687","display_name":"Remote sensing","level":1,"score":0.09372439980506897},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007834","descriptor_name":"Lasers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007834","descriptor_name":"Lasers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007834","descriptor_name":"Lasers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007834","descriptor_name":"Lasers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010713","descriptor_name":"Phosphatidylcholines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010713","descriptor_name":"Phosphatidylcholines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010713","descriptor_name":"Phosphatidylcholines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010713","descriptor_name":"Phosphatidylcholines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013059","descriptor_name":"Spectrum Analysis, Raman","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015060","descriptor_name":"1,2-Dipalmitoylphosphatidylcholine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015060","descriptor_name":"1,2-Dipalmitoylphosphatidylcholine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015060","descriptor_name":"1,2-Dipalmitoylphosphatidylcholine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015060","descriptor_name":"1,2-Dipalmitoylphosphatidylcholine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1021/jp308938t","doi":"https://doi.org/10.1021/jp308938t","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jp308938t","pdf_url":null,"source":{"id":"https://openalex.org/S185621672","display_name":"The Journal of Physical Chemistry B","issn_l":"1520-5207","issn":["1520-5207","1520-6106"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Physical Chemistry B","raw_type":"journal-article"},{"id":"pmid:23256635","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23256635","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of physical chemistry. B","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2974256","doi":null,"is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3637845","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3637845","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3637845","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Phys Chem B","raw_type":"Text"},{"id":"pmh:oai:dash.harvard.edu:1/10459029","doi":null,"is_oa":true,"landing_page_url":"http://nrs.harvard.edu/urn-3:HUL.InstRepos:10459029","pdf_url":null,"source":{"id":"https://openalex.org/S4306401540","display_name":"Digital Access to Scholarship at Harvard (DASH) (Harvard University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I136199984","host_organization_name":"Harvard University","host_organization_lineage":["https://openalex.org/I136199984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3637845","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3637845","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Phys Chem B","raw_type":"Text"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"display_name":"Life on land","score":0.5099999904632568,"id":"https://metadata.un.org/sdg/15"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1362727167","display_name":null,"funder_award_id":"R01 EB010244","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G8554672881","display_name":null,"funder_award_id":"1R01EB010244-01","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"}],"funders":[{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1495216676","https://openalex.org/W1765733519","https://openalex.org/W1969212158","https://openalex.org/W1976333807","https://openalex.org/W1977919076","https://openalex.org/W1982208794","https://openalex.org/W1982280153","https://openalex.org/W1982914783","https://openalex.org/W1986348950","https://openalex.org/W1989919875","https://openalex.org/W2021964673","https://openalex.org/W2026210999","https://openalex.org/W2031727322","https://openalex.org/W2038703722","https://openalex.org/W2045901799","https://openalex.org/W2046066571","https://openalex.org/W2050314707","https://openalex.org/W2052363099","https://openalex.org/W2060654966","https://openalex.org/W2060925749","https://openalex.org/W2063623305","https://openalex.org/W2070115914","https://openalex.org/W2071070545","https://openalex.org/W2071274854","https://openalex.org/W2073513617","https://openalex.org/W2092875135","https://openalex.org/W2096138335","https://openalex.org/W2102874009","https://openalex.org/W2104460891","https://openalex.org/W2111508436","https://openalex.org/W2112704930","https://openalex.org/W2115318086","https://openalex.org/W2116905766","https://openalex.org/W2132298953","https://openalex.org/W2134285663","https://openalex.org/W2136371540","https://openalex.org/W2143386071","https://openalex.org/W2148691803","https://openalex.org/W2150345928","https://openalex.org/W2159648456","https://openalex.org/W2163790025","https://openalex.org/W2169986236","https://openalex.org/W4236673977"],"related_works":["https://openalex.org/W2058549613","https://openalex.org/W4386427838","https://openalex.org/W3178760882","https://openalex.org/W2605253479","https://openalex.org/W2514046700","https://openalex.org/W2015356488","https://openalex.org/W2765547586","https://openalex.org/W2049189005","https://openalex.org/W2755556010","https://openalex.org/W2155702879"],"abstract_inverted_index":{"Raman":[0,19,26,41,52,92],"microscopy":[1,27,44],"is":[2,142],"a":[3,57,73,79,145],"quantitative,":[4],"label-free,":[5],"and":[6,32,100,166,173,185],"noninvasive":[7],"optical":[8],"imaging":[9,55,83,132,135,154,176],"technique":[10],"for":[11],"studying":[12,182],"inhomogeneous":[13,158],"systems.":[14,187],"However,":[15],"the":[16,23,48,63,70,97,116,138,156],"feebleness":[17],"of":[18,25,51,60,65,72,103,113,118,160,170],"scattering":[20,42],"significantly":[21,46],"limits":[22],"use":[24],"to":[28,89,128],"low":[29],"time":[30],"resolutions":[31],"primarily":[33],"static":[34],"samples.":[35],"Recent":[36],"developments":[37],"in":[38,115,137,181],"narrowband":[39,104],"stimulated":[40],"(SRS)":[43],"have":[45],"increased":[47],"acquisition":[49,94],"speed":[50,99],"based":[53],"label-free":[54,174],"by":[56],"few":[58],"orders":[59],"magnitude,":[61],"at":[62],"expense":[64],"reduced":[66],"spectroscopic":[67],"information.":[68],"On":[69],"basis":[71],"spectral":[74],"focusing":[75],"approach,":[76],"we":[77],"present":[78],"fast":[80,171],"SRS":[81,105,152],"hyperspectral":[82,134,153],"system":[84],"using":[85],"chirped":[86],"femtosecond":[87],"lasers":[88],"achieve":[90],"rapid":[91],"spectra":[93],"while":[95],"retaining":[96],"full":[98],"image":[101],"quality":[102],"imaging.":[106],"We":[107,147],"demonstrate":[108],"that":[109,149],"quantitative":[110],"concentration":[111],"determination":[112],"cholesterol":[114],"presence":[117],"interfering":[119],"chemical":[120,175],"species":[121],"can":[122],"be":[123],"achieved":[124],"with":[125],"sensitivity":[126],"down":[127],"4":[129],"mM.":[130],"For":[131],"purposes,":[133],"data":[136],"C-H":[139],"stretching":[140],"region":[141],"obtained":[143],"within":[144],"minute.":[146],"show":[148],"mammalian":[150],"cell":[151],"reveals":[155],"spatially":[157],"distribution":[159],"saturated":[161],"lipids,":[162,164],"unsaturated":[163],"cholesterol,":[165],"protein.":[167],"The":[168],"combination":[169],"spectroscopy":[172],"will":[177],"enable":[178],"new":[179],"applications":[180],"biological":[183],"systems":[184],"material":[186]},"counts_by_year":[{"year":2026,"cited_by_count":19},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":28},{"year":2023,"cited_by_count":30},{"year":2022,"cited_by_count":25},{"year":2021,"cited_by_count":32},{"year":2020,"cited_by_count":20},{"year":2019,"cited_by_count":23},{"year":2018,"cited_by_count":28},{"year":2017,"cited_by_count":23},{"year":2016,"cited_by_count":22},{"year":2015,"cited_by_count":20},{"year":2014,"cited_by_count":21},{"year":2013,"cited_by_count":11}],"updated_date":"2026-10-22T09:42:04.148104","created_date":"2025-10-10T00:00:00"}