{"id":"https://openalex.org/W2138793231","doi":"https://doi.org/10.1093/brain/awn167","title":"Enuresis as a premorbid developmental marker of schizophrenia","display_name":"Enuresis as a premorbid developmental marker of schizophrenia","publication_year":2008,"publication_date":"2008-08-01","ids":{"openalex":"https://openalex.org/W2138793231","doi":"https://doi.org/10.1093/brain/awn167","mag":"2138793231","pmid":"https://pubmed.ncbi.nlm.nih.gov/18669483","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2536601"},"language":"en","primary_location":{"id":"doi:10.1093/brain/awn167","doi":"https://doi.org/10.1093/brain/awn167","is_oa":false,"landing_page_url":"https://doi.org/10.1093/brain/awn167","pdf_url":null,"source":{"id":"https://openalex.org/S118357697","display_name":"Brain","issn_l":"0006-8950","issn":["0006-8950","1460-2156"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2536601","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056413476","display_name":"Thomas M. Hyde","orcid":"https://orcid.org/0000-0002-8746-3037","observed_orcids":["https://orcid.org/0000-0002-8746-3037"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. M. Hyde","raw_affiliation_strings":["Clinical Brain Disorders Branch, NIMH/DIRP/NIH, Bethesda, MD 20892, USA. hydet@mail.nih.gov","Clinical Brain Disorders Branch, NIMH/DIRP/NIH, Bethesda, MD 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, NIMH/DIRP/NIH, Bethesda, MD 20892, USA. hydet@mail.nih.gov","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210158500"]},{"raw_affiliation_string":"Clinical Brain Disorders Branch, NIMH/DIRP/NIH, Bethesda, MD 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062271906","display_name":"Amy Deep\u2010Soboslay","orcid":"https://orcid.org/0000-0002-7762-8942","observed_orcids":["https://orcid.org/0000-0002-7762-8942"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Deep-Soboslay","raw_affiliation_strings":["Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":null,"display_name":"B. Iglesias","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B. Iglesias","raw_affiliation_strings":["Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015541901","display_name":"Joseph H. Callicott","orcid":"https://orcid.org/0000-0003-1298-3334","observed_orcids":["https://orcid.org/0000-0003-1298-3334"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. H. Callicott","raw_affiliation_strings":["Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028131133","display_name":"James M. Gold","orcid":"https://orcid.org/0000-0002-0109-9554","observed_orcids":["https://orcid.org/0000-0002-0109-9554"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. M. Gold","raw_affiliation_strings":["Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006015276","display_name":"Andreas Meyer\u2010Lindenberg","orcid":"https://orcid.org/0000-0001-5619-1123","observed_orcids":["https://orcid.org/0000-0001-5619-1123"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Meyer-Lindenberg","raw_affiliation_strings":["Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069883581","display_name":"Robyn A. Honea","orcid":"https://orcid.org/0000-0002-4661-2024","observed_orcids":["https://orcid.org/0000-0002-4661-2024"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. A. Honea","raw_affiliation_strings":["Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108888132","display_name":"Llewellyn B. Bigelow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. B. Bigelow","raw_affiliation_strings":["Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053074980","display_name":"Michael F. Egan","orcid":"https://orcid.org/0000-0002-9709-1206","observed_orcids":["https://orcid.org/0000-0002-9709-1206"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. F. Egan","raw_affiliation_strings":["Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5097176933","display_name":"E. M. Emsellem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. M. Emsellem","raw_affiliation_strings":["Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043264677","display_name":"Daniel R. Weinberger","orcid":"https://orcid.org/0000-0003-2409-2969","observed_orcids":["https://orcid.org/0000-0003-2409-2969","https://orcid.org/0000-0003-1178-8086"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. R. Weinberger","raw_affiliation_strings":["Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Brain Disorders Branch, 2 Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore and 3 Genes, Cognition, and Psychosis Program, NIMH/DIRP/NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4224,"currency":"GBP","value_usd":5570},"apc_paid":null,"fwci":2.3361,"has_fulltext":false,"cited_by_count":46,"citation_normalized_percentile":{"value":0.87517871,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"131","issue":"9","first_page":"2489","last_page":"2498"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10565","display_name":"Psychopathy, Forensic Psychiatry, Sexual Offending","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.9769999980926514},{"id":"https://openalex.org/keywords/neurodevelopmental-delay","display_name":"neurodevelopmental delay","score":0.9639999866485596},{"id":"https://openalex.org/keywords/gray-matter-reduction","display_name":"gray matter reduction","score":0.8650000095367432},{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"prefrontal cortex","score":0.9390000104904175},{"id":"https://openalex.org/keywords/phonemic-fluency","display_name":"phonemic fluency","score":0.7369999885559082},{"id":"https://openalex.org/keywords/semantic-fluency","display_name":"semantic fluency","score":0.9409999847412109},{"id":"https://openalex.org/keywords/siblings-of-schizophrenic-patients","display_name":"siblings of schizophrenic patients","score":0.7210000157356262},{"id":"https://openalex.org/keywords/voxel-based-morphometry","display_name":"voxel-based morphometry","score":0.7289999723434448},{"id":"https://openalex.org/keywords/superior-parietal-cortex","display_name":"superior parietal cortex","score":0.699999988079071},{"id":"https://openalex.org/keywords/brain-maturation","display_name":"brain maturation","score":0.3179999887943268},{"id":"https://openalex.org/keywords/schizophrenia-risk-factors","display_name":"schizophrenia risk factors","score":0.4860000014305115},{"id":"https://openalex.org/keywords/neuropsychological-assessment","display_name":"neuropsychological assessment","score":0.43299999833106995},{"id":"https://openalex.org/keywords/brain-mri-volumetry","display_name":"brain MRI volumetry","score":0.6460000276565552},{"id":"https://openalex.org/keywords/frontal-lobe","display_name":"frontal lobe","score":0.3529999852180481}],"concepts":[{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.6566144227981567},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6048981547355652},{"id":"https://openalex.org/C2780610425","wikidata":"https://www.wikidata.org/wiki/Q3448862","display_name":"Enuresis","level":2,"score":0.5871628522872925},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.353414922952652},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.3485962152481079},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3463139533996582}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004775","descriptor_name":"Enuresis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D004775","descriptor_name":"Enuresis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004775","descriptor_name":"Enuresis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004775","descriptor_name":"Enuresis","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009483","descriptor_name":"Neuropsychological Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012565","descriptor_name":"Schizophrenic Psychology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039721","descriptor_name":"Diagnostic and Statistical Manual of Mental Disorders","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1093/brain/awn167","doi":"https://doi.org/10.1093/brain/awn167","is_oa":false,"landing_page_url":"https://doi.org/10.1093/brain/awn167","pdf_url":null,"source":{"id":"https://openalex.org/S118357697","display_name":"Brain","issn_l":"0006-8950","issn":["0006-8950","1460-2156"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1501362","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2536601","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2536601","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2536601","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain","raw_type":"Text"},{"id":"pmid:18669483","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18669483","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain : a journal of neurology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.565.4923","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.565.4923","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://brain.oxfordjournals.org/content/131/9/2489.full.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.607.6042","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.607.6042","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://brain.oxfordjournals.org/content/early/2008/07/31/brain.awn167.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1501362","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2536601","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.6399999856948853,"display_name":"Quality education","id":"https://metadata.un.org/sdg/4"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G4722307765","display_name":"Biological Characterization of Genetic Mechanisms in Neuropsychiatric Disorders","funder_award_id":"Z01MH002904","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W43833092","https://openalex.org/W75905022","https://openalex.org/W163952196","https://openalex.org/W1562731484","https://openalex.org/W1641197739","https://openalex.org/W1755739160","https://openalex.org/W1839267428","https://openalex.org/W1931515001","https://openalex.org/W1964213490","https://openalex.org/W1965876274","https://openalex.org/W1967443916","https://openalex.org/W1969219681","https://openalex.org/W1976746717","https://openalex.org/W1979587668","https://openalex.org/W1980350735","https://openalex.org/W1990994978","https://openalex.org/W1992140872","https://openalex.org/W2001617107","https://openalex.org/W2004453499","https://openalex.org/W2005827220","https://openalex.org/W2006260143","https://openalex.org/W2013373204","https://openalex.org/W2013678048","https://openalex.org/W2017806432","https://openalex.org/W2023018925","https://openalex.org/W2026300757","https://openalex.org/W2036809815","https://openalex.org/W2037554578","https://openalex.org/W2039845328","https://openalex.org/W2040113003","https://openalex.org/W2042868415","https://openalex.org/W2043298898","https://openalex.org/W2052421461","https://openalex.org/W2052894640","https://openalex.org/W2053728368","https://openalex.org/W2053783338","https://openalex.org/W2057161787","https://openalex.org/W2064277913","https://openalex.org/W2065580034","https://openalex.org/W2072430145","https://openalex.org/W2074531359","https://openalex.org/W2082927467","https://openalex.org/W2102505363","https://openalex.org/W2105504542","https://openalex.org/W2109000188","https://openalex.org/W2114515246","https://openalex.org/W2116649573","https://openalex.org/W2119848633","https://openalex.org/W2126033695","https://openalex.org/W2127495504","https://openalex.org/W2132964759","https://openalex.org/W2136082448","https://openalex.org/W2140076070","https://openalex.org/W2140422264","https://openalex.org/W2153525031","https://openalex.org/W2159006998","https://openalex.org/W2163938637","https://openalex.org/W2164534384","https://openalex.org/W2171678639","https://openalex.org/W2409262222","https://openalex.org/W2764732513","https://openalex.org/W4235019056","https://openalex.org/W4300025934"],"related_works":["https://openalex.org/W2740504721","https://openalex.org/W2095331780","https://openalex.org/W2042359572","https://openalex.org/W4362733343","https://openalex.org/W12580265","https://openalex.org/W2009256853","https://openalex.org/W2022782092","https://openalex.org/W2965645504","https://openalex.org/W3212833315","https://openalex.org/W1605769792"],"abstract_inverted_index":{"There":[0],"is":[1,27],"comparatively":[2],"little":[3],"information":[4],"about":[5],"premorbid":[6,310],"maturational":[7],"brain":[8,35,55,108],"abnormalities":[9,36,289,314],"in":[10,63,186,238,259,290,295,327],"schizophrenia":[11],"(SCZ).":[12],"We":[13],"investigated":[14],"whether":[15],"a":[16,21,262,298,309],"history":[17,51,263,300],"of":[18,24,34,46,52,83,94,118,156,264,282,301],"childhood":[19,157,283,299,305],"enuresis,":[20,53],"well-established":[22],"marker":[23,311],"neurodevelopmental":[25,313],"delay,":[26],"associated":[28,38,285],"with":[29,32,39,65,102,123,139,151,161,192,227,261,268,286,297],"SCZ":[30,152,287],"and":[31,43,58,71,88,100,106,134,179,213,248,252,288,293],"measures":[33],"also":[37],"SCZ.":[40,317],"A":[41],"Diagnostic":[42],"Statistical":[44],"Manual":[45],"Mental":[47],"Disorders":[48],"(DSM-IV)":[49],"based":[50],"volumetric":[54],"MRI":[56],"scans":[57],"neuropsychological":[59],"testing":[60],"were":[61,77,110],"obtained":[62],"patients":[64,79,260,270,296],"SCZ,":[66],"their":[67,84],"non-psychotic":[68],"siblings":[69],"(SIB)":[70],"non-psychiatric":[72],"controls":[73,90,135,171],"(NC).":[74],"The":[75,279],"subjects":[76],"211":[78],"(79.6%":[80],"male),":[81],"234":[82],"SIB":[85,162,187],"(43.2%":[86],"male)":[87],"355":[89],"(39.2%":[91],"male).":[92],"Frequency":[93],"enuresis":[95,126,142,158,183,193,265,284,302,306],"was":[96,184],"compared":[97,160,226,267],"across":[98],"groups":[99],"correlated":[101],"cognitive":[103,200],"measures.":[104],"Total":[105],"regional":[107],"volumes":[109],"determined":[111],"using":[112],"voxel-based":[113],"morphometry":[114,231],"on":[115,196],"matched":[116],"subsets":[117],"probands":[119],"(n":[120,127,136,143],"=":[121,128,131,137,144,147,165,168,174,189,205,208,211,217,220,223],"82)":[122],"or":[124,140,170],"without":[125,141],"16,":[129],"n":[130,146],"66,":[132],"respectively)":[133],"102)":[138],"11,":[145],"91,":[148],"respectively).":[149],"Patients":[150,191],"had":[153],"higher":[154],"rates":[155],"(21%)":[159],"(11%;":[163],"chi(2)":[164,173],"6.42,":[166],"P":[167,176,207,219,276],"0.01)":[169],"(7%;":[172],"23.65,":[175],"<":[177,277],"0.0001)":[178],"relative":[180],"risk":[181,334],"for":[182,312],"increased":[185],"(lambda(S)":[188],"2.62).":[190],"performed":[194],"worse":[195],"two":[197],"frontal":[198,240],"lobe":[199],"tests":[201],"[Letter":[202],"Fluency":[203,215],"(t":[204,216],"1.97,":[206],"0.05,":[209],"df":[210,222],"200)":[212],"Category":[214],"2.15,":[218],"0.03,":[221],"200)]":[224],"as":[225,266],"non-enuretic":[228,269],"patients.":[229],"Voxel-based":[230],"analysis":[232],"revealed":[233],"grey":[234],"matter":[235],"volume":[236],"reductions":[237],"several":[239],"regions":[241],"(right":[242],"BA":[243,246,250],"9,":[244],"right":[245,253],"10":[247],"bilateral":[249],"45)":[251],"superior":[254],"parietal":[255],"cortex":[256],"(BA":[257],"7)":[258],"(all":[271],"t":[272],">":[273],"3.57,":[274],"all":[275],"0.001).":[278],"high":[280],"frequency":[281],"prefrontal":[291,325],"function":[292],"structure":[294],"suggest":[303],"that":[304],"may":[307],"be":[308],"related":[315,331],"to":[316,321,332],"These":[318],"findings":[319],"add":[320],"the":[322],"evidence":[323],"implicating":[324],"dysmaturation":[326],"this":[328],"disorder,":[329],"potentially":[330],"genetic":[333],"factors.":[335]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
