{"id":"https://openalex.org/W2138308529","doi":"https://doi.org/10.1128/aac.44.10.2880-2882.2000","title":"Bactericidal Activity of Quinupristin-Dalfopristin against Staphylococcus aureus : Clindamycin Susceptibility as a Surrogate Indicator","display_name":"Bactericidal Activity of Quinupristin-Dalfopristin against Staphylococcus aureus : Clindamycin Susceptibility as a Surrogate Indicator","publication_year":2000,"publication_date":"2000-10-01","ids":{"openalex":"https://openalex.org/W2138308529","doi":"https://doi.org/10.1128/aac.44.10.2880-2882.2000","mag":"2138308529","pmid":"https://pubmed.ncbi.nlm.nih.gov/10991879","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/90170"},"language":"en","primary_location":{"id":"doi:10.1128/aac.44.10.2880-2882.2000","doi":"https://doi.org/10.1128/aac.44.10.2880-2882.2000","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aac.44.10.2880-2882.2000","pdf_url":null,"source":{"id":"https://openalex.org/S47215897","display_name":"Antimicrobial Agents and Chemotherapy","issn_l":"0066-4804","issn":["0066-4804","1070-6283","1098-6596"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Agents and Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC90170","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011839226","display_name":"PETER C. FUCHS","orcid":"https://orcid.org/0000-0003-3933-7674","observed_orcids":["https://orcid.org/0000-0003-3933-7674"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter C. Fuchs","raw_affiliation_strings":["<!--label omitted: 1-->The Clinical Microbiology Institute, Wilsonville, Oregon","The Clinical Microbiology Institute, Wilsonville, Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->The Clinical Microbiology Institute, Wilsonville, Oregon","institution_ids":[]},{"raw_affiliation_string":"The Clinical Microbiology Institute, Wilsonville, Oregon","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113777507","display_name":"Arthur L. Barry","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arthur L. Barry","raw_affiliation_strings":["<!--label omitted: 1-->The Clinical Microbiology Institute, Wilsonville, Oregon","The Clinical Microbiology Institute, Wilsonville, Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->The Clinical Microbiology Institute, Wilsonville, Oregon","institution_ids":[]},{"raw_affiliation_string":"The Clinical Microbiology Institute, Wilsonville, Oregon","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019407143","display_name":"Steven D. Brown","orcid":"https://orcid.org/0000-0002-9281-3898","observed_orcids":["https://orcid.org/0000-0002-9281-3898"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven D. Brown","raw_affiliation_strings":["<!--label omitted: 1-->The Clinical Microbiology Institute, Wilsonville, Oregon","The Clinical Microbiology Institute, Wilsonville, Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->The Clinical Microbiology Institute, Wilsonville, Oregon","institution_ids":[]},{"raw_affiliation_string":"The Clinical Microbiology Institute, Wilsonville, Oregon","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.604,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.89613772,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"44","issue":"10","first_page":"2880","last_page":"2882"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/quinupristin-dalfopristin","display_name":"quinupristin/dalfopristin","score":1.0},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bactericidal-activity","display_name":"bactericidal activity","score":0.9850000143051147},{"id":"https://openalex.org/keywords/clindamycin-susceptibility","display_name":"clindamycin susceptibility","score":0.9769999980926514},{"id":"https://openalex.org/keywords/clindamycin-resistance","display_name":"clindamycin resistance","score":0.8159999847412109},{"id":"https://openalex.org/keywords/macrolide-resistance","display_name":"macrolide resistance","score":0.9959999918937683},{"id":"https://openalex.org/keywords/vancomycin","display_name":"vancomycin","score":0.828000009059906},{"id":"https://openalex.org/keywords/antimicrobial-susceptibility-testing","display_name":"antimicrobial susceptibility testing","score":0.5950000286102295}],"concepts":[{"id":"https://openalex.org/C2777874012","wikidata":"https://www.wikidata.org/wiki/Q5210829","display_name":"Dalfopristin","level":5,"score":0.971023440361023},{"id":"https://openalex.org/C2780944852","wikidata":"https://www.wikidata.org/wiki/Q7272542","display_name":"Quinupristin","level":5,"score":0.9665223360061646},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.727717936038971},{"id":"https://openalex.org/C2777458120","wikidata":"https://www.wikidata.org/wiki/Q422273","display_name":"Clindamycin","level":3,"score":0.7158834934234619},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.6748250126838684},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5429039597511292},{"id":"https://openalex.org/C2779427427","wikidata":"https://www.wikidata.org/wiki/Q3560696","display_name":"Virginiamycin","level":3,"score":0.5077258348464966},{"id":"https://openalex.org/C2778980435","wikidata":"https://www.wikidata.org/wiki/Q424027","display_name":"Vancomycin","level":4,"score":0.40390318632125854},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39216679334640503},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.11758282780647278},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002981","descriptor_name":"Clindamycin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004352","descriptor_name":"Drug Resistance, Microbial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014640","descriptor_name":"Vancomycin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014769","descriptor_name":"Virginiamycin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1128/aac.44.10.2880-2882.2000","doi":"https://doi.org/10.1128/aac.44.10.2880-2882.2000","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aac.44.10.2880-2882.2000","pdf_url":null,"source":{"id":"https://openalex.org/S47215897","display_name":"Antimicrobial Agents and Chemotherapy","issn_l":"0066-4804","issn":["0066-4804","1070-6283","1098-6596"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Agents and Chemotherapy","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:172494","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC90170","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:90170","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/90170","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrob Agents Chemother","raw_type":"Text"},{"id":"pmid:10991879","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10991879","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial agents and chemotherapy","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:172494","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC90170","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1505626160","https://openalex.org/W1581962345","https://openalex.org/W1963937797","https://openalex.org/W1999463347","https://openalex.org/W2014141958","https://openalex.org/W2030373904","https://openalex.org/W2039206959","https://openalex.org/W2059497489","https://openalex.org/W2089768466","https://openalex.org/W2093501573","https://openalex.org/W2097264824","https://openalex.org/W2114830802","https://openalex.org/W2128432333","https://openalex.org/W2157620025","https://openalex.org/W2161863616","https://openalex.org/W2187292340","https://openalex.org/W2327946322","https://openalex.org/W2474690725"],"related_works":["https://openalex.org/W2187292340","https://openalex.org/W2005776364","https://openalex.org/W7098013313","https://openalex.org/W1966752699","https://openalex.org/W1977985780","https://openalex.org/W2138228124","https://openalex.org/W2006833300","https://openalex.org/W1992819072","https://openalex.org/W2098470657","https://openalex.org/W2069764314"],"abstract_inverted_index":{"Of":[0],"516":[1],"Staphylococcus":[2],"aureus":[3],"strains":[4,20,30,42],"tested,":[5,21],"97.1%":[6],"were":[7,31,44,47],"susceptible":[8],"to":[9,23],"quinupristin-dalfopristin,":[10,37],"which":[11],"was":[12],"bactericidal":[13],"for":[14],"22":[15,40],"(56%)":[16],"of":[17],"the":[18],"39":[19],"comparable":[22],"vancomycin.":[24],"All":[25],"17":[26],"clindamycin":[27],"and":[28],"macrolide-resistant":[29],"inhibited":[32],"but":[33],"not":[34],"killed":[35],"by":[36],"whereas":[38],"all":[39],"clindamycin-susceptible":[41],"(5":[43],"macrolide":[45],"resistant)":[46],"killed.":[48]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}