{"id":"https://openalex.org/W2138229865","doi":"https://doi.org/10.1085/jgp.200409091","title":"The Early History of the Biochemistry of Muscle Contraction","display_name":"The Early History of the Biochemistry of Muscle Contraction","publication_year":2004,"publication_date":"2004-06-01","ids":{"openalex":"https://openalex.org/W2138229865","doi":"https://doi.org/10.1085/jgp.200409091","mag":"2138229865","pmid":"https://pubmed.ncbi.nlm.nih.gov/15173217","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2234565"},"language":"en","primary_location":{"id":"doi:10.1085/jgp.200409091","doi":"https://doi.org/10.1085/jgp.200409091","is_oa":true,"landing_page_url":"https://doi.org/10.1085/jgp.200409091","pdf_url":"https://rupress.org/jgp/article-pdf/123/6/631/1151185/jgp1236631.pdf","source":{"id":"https://openalex.org/S168548653","display_name":"The Journal of General Physiology","issn_l":"0022-1295","issn":["0022-1295","1540-7748"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of General Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://rupress.org/jgp/article-pdf/123/6/631/1151185/jgp1236631.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109568825","display_name":"Andrew G. Szent\u2010Gy\u00f6rgyi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I6902469","display_name":"Brandeis University","ror":"https://ror.org/05abbep66","country_code":"US","type":"education","lineage":["https://openalex.org/I6902469"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andrew G. Szent-Gyo\u0308rgyi","raw_affiliation_strings":["Rosenstiel Basic Medical Research Center, Brandeis University, Waltham, MA 02254"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rosenstiel Basic Medical Research Center, Brandeis University, Waltham, MA 02254","institution_ids":["https://openalex.org/I6902469"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5109568825"],"corresponding_institution_ids":["https://openalex.org/I6902469"],"apc_list":null,"apc_paid":null,"fwci":17.1981,"has_fulltext":true,"cited_by_count":141,"citation_normalized_percentile":{"value":0.98953986,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"123","issue":"6","first_page":"631","last_page":"641"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14475","display_name":"History of Science and Medicine","score":0.8901000022888184,"subfield":{"id":"https://openalex.org/subfields/1207","display_name":"History and Philosophy of Science"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T14475","display_name":"History of Science and Medicine","score":0.8901000022888184,"subfield":{"id":"https://openalex.org/subfields/1207","display_name":"History and Philosophy of Science"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12990","display_name":"Medical History and Innovations","score":0.016100000590085983,"subfield":{"id":"https://openalex.org/subfields/1202","display_name":"History"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.01549999974668026,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/muscle-contraction","display_name":"muscle contraction","score":0.9789999723434448},{"id":"https://openalex.org/keywords/history-of-biochemistry","display_name":"history of biochemistry","score":0.8029999732971191},{"id":"https://openalex.org/keywords/striated-muscle","display_name":"striated muscle","score":0.9869999885559082},{"id":"https://openalex.org/keywords/muscle-physiology","display_name":"muscle physiology","score":0.4749999940395355},{"id":"https://openalex.org/keywords/history-of-science","display_name":"history of science","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C2776050358","wikidata":"https://www.wikidata.org/wiki/Q127006","display_name":"Muscle contraction","level":2,"score":0.6048336625099182},{"id":"https://openalex.org/C163415756","wikidata":"https://www.wikidata.org/wiki/Q126473","display_name":"Contraction (grammar)","level":2,"score":0.5838942527770996},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.39015993475914},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37129491567611694},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.32084643840789795},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26186829805374146},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.13485756516456604}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001671","descriptor_name":"Biochemistry","qualifier_ui":"Q000266","qualifier_name":"history","is_major_topic":true},{"descriptor_ui":"D005060","descriptor_name":"Europe","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020409","descriptor_name":"Molecular Motor Proteins","qualifier_ui":"Q000266","qualifier_name":"history","is_major_topic":true},{"descriptor_ui":"D020409","descriptor_name":"Molecular Motor Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D049672","descriptor_name":"History, 19th Century","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049673","descriptor_name":"History, 20th Century","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1085/jgp.200409091","doi":"https://doi.org/10.1085/jgp.200409091","is_oa":true,"landing_page_url":"https://doi.org/10.1085/jgp.200409091","pdf_url":"https://rupress.org/jgp/article-pdf/123/6/631/1151185/jgp1236631.pdf","source":{"id":"https://openalex.org/S168548653","display_name":"The Journal of General Physiology","issn_l":"0022-1295","issn":["0022-1295","1540-7748"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of General Physiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:776182","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2234565","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2234565","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2234565","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Gen Physiol","raw_type":"Text"},{"id":"pmid:15173217","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15173217","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of general physiology","raw_type":"Seminal Article"}],"best_oa_location":{"id":"doi:10.1085/jgp.200409091","doi":"https://doi.org/10.1085/jgp.200409091","is_oa":true,"landing_page_url":"https://doi.org/10.1085/jgp.200409091","pdf_url":"https://rupress.org/jgp/article-pdf/123/6/631/1151185/jgp1236631.pdf","source":{"id":"https://openalex.org/S168548653","display_name":"The Journal of General Physiology","issn_l":"0022-1295","issn":["0022-1295","1540-7748"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of General Physiology","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.4099999964237213}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2138229865.pdf","grobid_xml":"https://content.openalex.org/works/W2138229865.grobid-xml"},"referenced_works_count":110,"referenced_works":["https://openalex.org/W2200570","https://openalex.org/W4359307","https://openalex.org/W52536779","https://openalex.org/W57290369","https://openalex.org/W104776524","https://openalex.org/W185094191","https://openalex.org/W196117794","https://openalex.org/W789458867","https://openalex.org/W965130420","https://openalex.org/W1484816165","https://openalex.org/W1487092966","https://openalex.org/W1488122477","https://openalex.org/W1498962226","https://openalex.org/W1507842415","https://openalex.org/W1533173993","https://openalex.org/W1538939790","https://openalex.org/W1583223274","https://openalex.org/W1590234561","https://openalex.org/W1614508806","https://openalex.org/W1642097468","https://openalex.org/W1753054392","https://openalex.org/W1856856507","https://openalex.org/W1916349104","https://openalex.org/W1936818573","https://openalex.org/W1965768931","https://openalex.org/W1966424667","https://openalex.org/W1966838368","https://openalex.org/W1968778374","https://openalex.org/W1972994243","https://openalex.org/W1975714515","https://openalex.org/W1976229578","https://openalex.org/W1978996331","https://openalex.org/W1979083058","https://openalex.org/W1979507072","https://openalex.org/W1981414344","https://openalex.org/W1983289051","https://openalex.org/W1983468648","https://openalex.org/W1985502887","https://openalex.org/W1987034229","https://openalex.org/W1989255509","https://openalex.org/W1989903056","https://openalex.org/W1994094998","https://openalex.org/W1998285398","https://openalex.org/W2003300699","https://openalex.org/W2006998430","https://openalex.org/W2007110441","https://openalex.org/W2011993103","https://openalex.org/W2015996376","https://openalex.org/W2017158016","https://openalex.org/W2018558852","https://openalex.org/W2021292333","https://openalex.org/W2025189895","https://openalex.org/W2026145805","https://openalex.org/W2026836008","https://openalex.org/W2030407057","https://openalex.org/W2030594014","https://openalex.org/W2035703000","https://openalex.org/W2036162307","https://openalex.org/W2038855834","https://openalex.org/W2044654888","https://openalex.org/W2044727592","https://openalex.org/W2048866389","https://openalex.org/W2049607475","https://openalex.org/W2051165421","https://openalex.org/W2051447352","https://openalex.org/W2057976520","https://openalex.org/W2059158601","https://openalex.org/W2060141710","https://openalex.org/W2060442105","https://openalex.org/W2062155011","https://openalex.org/W2064894513","https://openalex.org/W2065599864","https://openalex.org/W2067044612","https://openalex.org/W2069597518","https://openalex.org/W2070118536","https://openalex.org/W2070122055","https://openalex.org/W2070342792","https://openalex.org/W2072529314","https://openalex.org/W2076008141","https://openalex.org/W2085568054","https://openalex.org/W2085573758","https://openalex.org/W2086751691","https://openalex.org/W2087544793","https://openalex.org/W2089114409","https://openalex.org/W2089608395","https://openalex.org/W2094626045","https://openalex.org/W2107779780","https://openalex.org/W2113092027","https://openalex.org/W2118264341","https://openalex.org/W2136904046","https://openalex.org/W2146793508","https://openalex.org/W2165444693","https://openalex.org/W2170545056","https://openalex.org/W2173664000","https://openalex.org/W2218720641","https://openalex.org/W2242855238","https://openalex.org/W2295790750","https://openalex.org/W2317995976","https://openalex.org/W2321370584","https://openalex.org/W2326712047","https://openalex.org/W2332193780","https://openalex.org/W2334869316","https://openalex.org/W2337885239","https://openalex.org/W2394968929","https://openalex.org/W2400825974","https://openalex.org/W2413825009","https://openalex.org/W2419865786","https://openalex.org/W2462264423","https://openalex.org/W4285719527","https://openalex.org/W4317676356"],"related_works":["https://openalex.org/W7099743302","https://openalex.org/W4233496312","https://openalex.org/W1038716722","https://openalex.org/W410222074","https://openalex.org/W77397995","https://openalex.org/W245034527","https://openalex.org/W1515067505","https://openalex.org/W1983285977","https://openalex.org/W2077256000","https://openalex.org/W2520045326"],"abstract_inverted_index":{"Since":[0],"antiquity,":[1],"motion":[2,15],"has":[3],"been":[4],"looked":[5],"upon":[6],"as":[7],"the":[8,22,44],"index":[9],"of":[10,14,21,24],"life.":[11],"The":[12,39],"organ":[13],"is":[16,26],"muscle.":[17,38],"Our":[18],"present":[19],"understanding":[20],"mechanism":[23],"contraction":[25],"based":[27],"on":[28,36],"three":[29],"fundamental":[30],"discoveries,":[31],"all":[32],"arising":[33],"from":[34],"studies":[35],"striated":[37],"modern":[40],"era":[41],"began":[42],"with":[43],"demonstration":[45],"that":[46]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":17},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":9}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}