{"id":"https://openalex.org/W2138014753","doi":null,"title":"Is serum vitamin D levels associated with disability in patients with newly diagnosed multiple sclerosis?","display_name":"Is serum vitamin D levels associated with disability in patients with newly diagnosed multiple sclerosis?","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2138014753","mag":"2138014753","pmid":"https://pubmed.ncbi.nlm.nih.gov/24250900","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3829281"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3829281","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3829281/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3829281/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iran J Neurol","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3829281/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066685557","display_name":"Hamidreza Hatamian","orcid":"https://orcid.org/0000-0002-4432-0482","observed_orcids":["https://orcid.org/0000-0002-4432-0482"]},"institutions":[{"id":"https://openalex.org/I204331812","display_name":"Guilan University of Medical Sciences","ror":"https://ror.org/04ptbrd12","country_code":"IR","type":"education","lineage":["https://openalex.org/I204331812","https://openalex.org/I4210110574"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Hamidreza Hatamian","raw_affiliation_strings":["Associate Professor, Department of Neurology, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Associate Professor, Department of Neurology, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran","institution_ids":["https://openalex.org/I204331812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012197267","display_name":"Elham Bidabadi","orcid":"https://orcid.org/0000-0002-1067-3335","observed_orcids":["https://orcid.org/0000-0002-1067-3335"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elham Bidabadi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061791722","display_name":"Seyed Mohammad Seyed Saadat","orcid":"https://orcid.org/0000-0001-8188-3455","observed_orcids":["https://orcid.org/0000-0001-8188-3455"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seyed Mohammad Seyed Saadat","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068862840","display_name":"Niloufar Seyed Saadat","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Niloufar Seyed Saadat","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108562572","display_name":"Ehsan Kazemnezhad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ehsan Kazemnezhad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057967975","display_name":"Hamed Ramezani","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hamed Ramezani","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111986644","display_name":"Babak Bakhshayesh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Babak Bakhshayesh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9755,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.85310577,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"12","issue":"2","first_page":"41","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.033900000154972076,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/vitamin-d","display_name":"vitamin D","score":0.8379999995231628},{"id":"https://openalex.org/keywords/serum-vitamin-d-levels","display_name":"serum vitamin D levels","score":0.9909999966621399},{"id":"https://openalex.org/keywords/disability","display_name":"disability","score":0.9240000247955322},{"id":"https://openalex.org/keywords/expanded-disability-status-scale","display_name":"Expanded Disability Status Scale","score":0.9990000128746033},{"id":"https://openalex.org/keywords/environmental-risk-factors","display_name":"environmental risk factors","score":0.8880000114440918},{"id":"https://openalex.org/keywords/disease-modifying-therapy","display_name":"disease-modifying therapy","score":0.43799999356269836}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9387334585189819},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.7910205125808716},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.7203901410102844},{"id":"https://openalex.org/C2780892749","wikidata":"https://www.wikidata.org/wiki/Q929518","display_name":"Expanded Disability Status Scale","level":3,"score":0.6952359676361084},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6373118758201599},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.6238948106765747},{"id":"https://openalex.org/C48921125","wikidata":"https://www.wikidata.org/wiki/Q10861030","display_name":"Linear regression","level":2,"score":0.4938229024410248},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.43423497676849365},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.41925084590911865},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3249998092651367},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2258993685245514},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.13676807284355164},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:3829281","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3829281/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3829281/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iran J Neurol","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:2817425","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3829281","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:24250900","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24250900","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iranian journal of neurology","raw_type":"Journal Article"},{"id":"mag:2138014753","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24250900","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3829281","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3829281/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3829281/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iran J Neurol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2138014753.pdf","grobid_xml":"https://content.openalex.org/works/W2138014753.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W1493426333","https://openalex.org/W1566613745","https://openalex.org/W1627811745","https://openalex.org/W1965152135","https://openalex.org/W1983115602","https://openalex.org/W1999323493","https://openalex.org/W2006560920","https://openalex.org/W2008330041","https://openalex.org/W2025274236","https://openalex.org/W2034742236","https://openalex.org/W2039479870","https://openalex.org/W2040358703","https://openalex.org/W2046913201","https://openalex.org/W2064699411","https://openalex.org/W2070880071","https://openalex.org/W2071151577","https://openalex.org/W2086531225","https://openalex.org/W2091080592","https://openalex.org/W2106185842","https://openalex.org/W2106647095","https://openalex.org/W2108793314","https://openalex.org/W2109978145","https://openalex.org/W2110969196","https://openalex.org/W2111127382","https://openalex.org/W2111516307","https://openalex.org/W2114101329","https://openalex.org/W2118855202","https://openalex.org/W2120309554","https://openalex.org/W2124927353","https://openalex.org/W2126574528","https://openalex.org/W2130234762","https://openalex.org/W2132003923","https://openalex.org/W2139204856","https://openalex.org/W2140560855","https://openalex.org/W2145184715","https://openalex.org/W2146805380","https://openalex.org/W2148423853","https://openalex.org/W2150049795","https://openalex.org/W2150137329","https://openalex.org/W2155048481","https://openalex.org/W2155356695","https://openalex.org/W2156478599","https://openalex.org/W2157845677","https://openalex.org/W2163470850"],"related_works":["https://openalex.org/W2185010499","https://openalex.org/W2610783540","https://openalex.org/W2626941010","https://openalex.org/W3127343786","https://openalex.org/W7096533526","https://openalex.org/W2574127378","https://openalex.org/W2006714354","https://openalex.org/W2763577943","https://openalex.org/W2998288695","https://openalex.org/W4301148672"],"abstract_inverted_index":{"BACKGROUND:":[0],"Although":[1],"the":[2,44,179],"precise":[3],"etiology":[4],"of":[5,38,47,73,105,169],"multiple":[6,126],"sclerosis":[7],"(MS)":[8],"is":[9],"unknown,":[10],"it":[11],"seems":[12],"that":[13,24],"both":[14,99],"genetic":[15],"and":[16,53,56,81,85,93,125,166],"environmental":[17,32],"factors":[18],"are":[19,30],"important.":[20],"Recent":[21],"studies":[22],"suggest":[23,186],"low":[25],"serum":[26,45,94,133,191],"vitamin":[27,48,95,134,163,192],"D":[28,49,96,135,164,193],"levels":[29,46,97,136,165,194],"important":[31],"factor":[33],"in":[34,63,142,148,197],"MS.":[35],"The":[36,131],"aim":[37],"this":[39,68],"study":[40],"was":[41,119],"to":[42,57],"compare":[43],"between":[50,162],"MS":[51,64,77,113,143,172,198],"patients":[52,75,114,144,170],"healthy":[54,89,149],"subjects,":[55],"determine":[58],"its":[59],"association":[60,161,189],"with":[61,76,87,171],"disability":[62,196],"patients.":[65,199],"METHODS:":[66],"In":[67],"cross-sectional":[69],"study,":[70],"a":[71,187],"total":[72],"52":[74,88],"were":[78,115,137],"randomly":[79],"recruited":[80],"matched":[82],"for":[83,98,112,178,190],"age":[84],"sex":[86],"subjects.":[90],"Demographic":[91],"characteristics":[92],"groups,":[100],"as":[101,103],"well":[102],"duration":[104],"disease":[106],"Expanded":[107],"Disability":[108],"Status":[109],"Scale":[110],"(EDSS)":[111],"evaluated.":[116],"Statistical":[117],"analysis":[118,157],"performed":[120],"by":[121],"independent":[122],"samples":[123],"t-test":[124],"linear":[127,155],"regression":[128,156],"analysis.":[129],"RESULTS:":[130],"mean":[132],"26.5":[138],"\u00b1":[139],"16.3":[140],"ng/ml":[141],"vs.":[145],"37.1":[146],"\u00b119.7":[147],"subjects":[150],"(P":[151,173],"=":[152,174],"0.003).":[153],"A":[154],"showed":[158],"no":[159],"significant":[160],"EDSS":[167],"score":[168],"0.345),":[175],"after":[176],"adjusting":[177],"covariates.":[180],"CONCLUSION:":[181],"Our":[182],"findings":[183],"did":[184],"not":[185],"protective":[188],"against":[195]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":5}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}