{"id":"https://openalex.org/W2137995000","doi":"https://doi.org/10.1089/aid.2013.0227","title":"Short Communication: Prospective Comparison of Qualitative Versus Quantitative Polymerase Chain Reaction for Monitoring Virologic Treatment Failure in HIV-Infected Patients","display_name":"Short Communication: Prospective Comparison of Qualitative Versus Quantitative Polymerase Chain Reaction for Monitoring Virologic Treatment Failure in HIV-Infected Patients","publication_year":2014,"publication_date":"2014-04-14","ids":{"openalex":"https://openalex.org/W2137995000","doi":"https://doi.org/10.1089/aid.2013.0227","mag":"2137995000","pmid":"https://pubmed.ncbi.nlm.nih.gov/24724838","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4118713"},"language":"en","primary_location":{"id":"doi:10.1089/aid.2013.0227","doi":"https://doi.org/10.1089/aid.2013.0227","is_oa":false,"landing_page_url":"https://doi.org/10.1089/aid.2013.0227","pdf_url":null,"source":{"id":"https://openalex.org/S161282271","display_name":"AIDS Research and Human Retroviruses","issn_l":"0889-2229","issn":["0889-2229","1931-8405"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS Research and Human Retroviruses","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4118713/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083828920","display_name":"Su Jin Jeong","orcid":"https://orcid.org/0000-0003-4025-4542","observed_orcids":["https://orcid.org/0000-0003-4025-4542"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Su Jin Jeong","raw_affiliation_strings":["AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102811216","display_name":"Min Hyung Kim","orcid":"https://orcid.org/0000-0003-0250-212X","observed_orcids":["https://orcid.org/0000-0003-0250-212X"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Min Hyung Kim","raw_affiliation_strings":["Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045724746","display_name":"Je Eun Song","orcid":"https://orcid.org/0000-0001-7056-6905","observed_orcids":["https://orcid.org/0000-0001-7056-6905"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Je Eun Song","raw_affiliation_strings":["Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081965566","display_name":"Jin Young Ahn","orcid":"https://orcid.org/0000-0002-3740-2826","observed_orcids":["https://orcid.org/0000-0002-3740-2826"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jin Young Ahn","raw_affiliation_strings":["Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038854401","display_name":"Sun Bean Kim","orcid":"https://orcid.org/0000-0002-8830-1144","observed_orcids":["https://orcid.org/0000-0002-8830-1144","https://orcid.org/0000-0002-9983-4392"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sun Bean Kim","raw_affiliation_strings":["AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111562994","display_name":"Hea Won Ann","orcid":"https://orcid.org/0000-0003-3170-0109","observed_orcids":["https://orcid.org/0000-0003-3170-0109"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hea Won Ann","raw_affiliation_strings":["Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000491897","display_name":"Jae Kyung Kim","orcid":"https://orcid.org/0000-0002-1534-563X","observed_orcids":["https://orcid.org/0000-0002-1534-563X"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jae Kyung Kim","raw_affiliation_strings":["AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046935423","display_name":"Heun Choi","orcid":"https://orcid.org/0000-0002-9622-9381","observed_orcids":["https://orcid.org/0000-0002-9622-9381"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Heun Choi","raw_affiliation_strings":["Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032103760","display_name":"Nam Su Ku","orcid":"https://orcid.org/0000-0002-9717-4327","observed_orcids":["https://orcid.org/0000-0002-9717-4327"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Nam Su Ku","raw_affiliation_strings":["AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041342083","display_name":"Sang Hoon Han","orcid":"https://orcid.org/0000-0002-4278-5198","observed_orcids":["https://orcid.org/0000-0002-4278-5198"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang Hoon Han","raw_affiliation_strings":["AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041277249","display_name":"June Myung Kim","orcid":"https://orcid.org/0000-0002-0337-8573","observed_orcids":["https://orcid.org/0000-0002-0337-8573"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"June Myung Kim","raw_affiliation_strings":["AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044677503","display_name":"Davey M. Smith","orcid":"https://orcid.org/0000-0003-3603-1733","observed_orcids":["https://orcid.org/0000-0003-3603-1733"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210099595","display_name":"VA San Diego Healthcare System","ror":"https://ror.org/00znqwq11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210099595","https://openalex.org/I4210138663"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Davey M. Smith","raw_affiliation_strings":["Department of Medicine, University of California San Diego, La Jolla, California","Veterans Affairs San Diego Healthcare System, San Diego, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of California San Diego, La Jolla, California","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Veterans Affairs San Diego Healthcare System, San Diego, California","institution_ids":["https://openalex.org/I4210099595"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hyon-Suk Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyon-Suk Kim","raw_affiliation_strings":["Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024506731","display_name":"Jun Yong Choi","orcid":"https://orcid.org/0000-0002-2775-3315","observed_orcids":["https://orcid.org/0000-0002-2775-3315","https://orcid.org/0000-0001-5874-4764"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jun Yong Choi","raw_affiliation_strings":["AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5024506731"],"corresponding_institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"],"apc_list":null,"apc_paid":null,"fwci":0.1263,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.3972973,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"30","issue":"8","first_page":"827","last_page":"829"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.4943999946117401,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.4943999946117401,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.36820000410079956,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.11940000206232071,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-1","display_name":"HIV-1","score":0.7829999923706055},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.9229999780654907},{"id":"https://openalex.org/keywords/hiv-1-reverse-transcriptase","display_name":"HIV-1 reverse transcriptase","score":0.7630000114440918},{"id":"https://openalex.org/keywords/qualitative-pcr","display_name":"qualitative PCR","score":0.7570000290870667},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.7009999752044678},{"id":"https://openalex.org/keywords/real-time-pcr","display_name":"real-time PCR","score":0.7110000252723694},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.6639999747276306},{"id":"https://openalex.org/keywords/cost-reduction","display_name":"cost reduction","score":0.7720000147819519},{"id":"https://openalex.org/keywords/plasma-hiv-rna","display_name":"plasma HIV RNA","score":0.5370000004768372},{"id":"https://openalex.org/keywords/treatment-response-monitoring","display_name":"treatment response monitoring","score":0.6959999799728394}],"concepts":[{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.6851011514663696},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.6834074854850769},{"id":"https://openalex.org/C48023723","wikidata":"https://www.wikidata.org/wiki/Q856198","display_name":"Real-time polymerase chain reaction","level":3,"score":0.6443577408790588},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5998159646987915},{"id":"https://openalex.org/C156719811","wikidata":"https://www.wikidata.org/wiki/Q28774","display_name":"Reverse transcriptase","level":4,"score":0.5660157203674316},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5475099086761475},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5442826747894287},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4855956435203552},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.471365362405777},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.45420241355895996},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3308830261230469},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3301931619644165},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32409897446632385},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0567743182182312},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016903","descriptor_name":"Drug Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017211","descriptor_name":"Treatment Failure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056910","descriptor_name":"Republic of Korea","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1089/aid.2013.0227","doi":"https://doi.org/10.1089/aid.2013.0227","is_oa":false,"landing_page_url":"https://doi.org/10.1089/aid.2013.0227","pdf_url":null,"source":{"id":"https://openalex.org/S161282271","display_name":"AIDS Research and Human Retroviruses","issn_l":"0889-2229","issn":["0889-2229","1931-8405"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS Research and Human Retroviruses","raw_type":"journal-article"},{"id":"pmid:24724838","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24724838","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS research and human retroviruses","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:4118713","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4118713/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS Res Hum Retroviruses","raw_type":"Text"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt27c952tm","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/27c952tm","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"AIDS Research and Human Retroviruses, vol 30, iss 8","raw_type":"article"},{"id":"pmh:oai:ir.ymlib.yonsei.ac.kr:22282913/99371","doi":null,"is_oa":true,"landing_page_url":"http://online.liebertpub.com/doi/abs/10.1089/aid.2013.0227","pdf_url":null,"source":{"id":"https://openalex.org/S4306400691","display_name":"YUHSpace (Yonsei University Medical Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193775966","host_organization_name":"Yonsei University","host_organization_lineage":["https://openalex.org/I193775966"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:qt27c952tm","doi":null,"is_oa":true,"landing_page_url":"http://www.escholarship.org/uc/item/27c952tm","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Jeong, Su Jin; Kim, Min Hyung; Song, Je Eun; Ahn, Jin Young; Kim, Sun Bean; Ann, Hea Won; \u00a0et al.(2014). Short communication: prospective comparison of qualitative versus quantitative polymerase chain reaction for monitoring virologic treatment failure in HIV-infected patients.. AIDS research and human retroviruses, 30(8), 827 - 829. doi: 10.1089/aid.2013.0227. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/27c952tm","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4118713","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4118713/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS Res Hum Retroviruses","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1782333790","display_name":null,"funder_award_id":"4800-4859-304","funder_id":"https://openalex.org/F4320332162","funder_display_name":"Centers for Disease Control and Prevention"},{"id":"https://openalex.org/G5183693899","display_name":"Mentoring Translational Research in HIV","funder_award_id":"K24AI100665","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5207410659","display_name":"Pooled Nucleic Acid Testing to Identify Antiretroviral Treatment Failure in India","funder_award_id":"R21AI080353","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G6456272567","display_name":null,"funder_award_id":"4800-4859- 304","funder_id":"https://openalex.org/F4320334882","funder_display_name":"Korea Centers for Disease Control and Prevention"},{"id":"https://openalex.org/G6507169123","display_name":"Molecular Epidemiology for HIV Prevention for Drug Users and Other Risk Groups ","funder_award_id":"DP1DA034978","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G7149330928","display_name":null,"funder_award_id":"4800-4859-304-260","funder_id":"https://openalex.org/F4320334882","funder_display_name":"Korea Centers for Disease Control and Prevention"},{"id":"https://openalex.org/G7685571301","display_name":null,"funder_award_id":"H\u2010GUARD_2013M3A6B2078953","funder_id":"https://openalex.org/F4320322030","funder_display_name":"Ministry of Science, ICT and Future Planning"},{"id":"https://openalex.org/G7816653090","display_name":null,"funder_award_id":"AI100665","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G9000866212","display_name":"San Diego Center for AIDS Research (SD CFAR)","funder_award_id":"P30AI036214","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G977897318","display_name":null,"funder_award_id":"NRF-2013R1A1A2005412","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"}],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320322030","display_name":"Ministry of Science, ICT and Future Planning","ror":"https://ror.org/032e49973"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"},{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"},{"id":"https://openalex.org/F4320334882","display_name":"Korea Centers for Disease Control and Prevention","ror":"https://ror.org/056za9j29"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1485082063","https://openalex.org/W1964645724","https://openalex.org/W1987415729","https://openalex.org/W1992278555","https://openalex.org/W1999846706","https://openalex.org/W2005881305","https://openalex.org/W2067122390","https://openalex.org/W2089680406","https://openalex.org/W2135901793","https://openalex.org/W2155991101","https://openalex.org/W2160967957","https://openalex.org/W2168405519"],"related_works":["https://openalex.org/W2613056340","https://openalex.org/W3197218566","https://openalex.org/W2462882660","https://openalex.org/W2002365564","https://openalex.org/W2074851952","https://openalex.org/W2417318835","https://openalex.org/W1973128718","https://openalex.org/W2140243859","https://openalex.org/W2168632583","https://openalex.org/W2085114799"],"abstract_inverted_index":{"Less":[0],"costly":[1],"but":[2],"still":[3],"accurate":[4],"methods":[5],"for":[6,25,64,100,183],"monitoring":[7,27,66],"HIV":[8,123,136,172],"treatment":[9],"response":[10],"are":[11],"needed.":[12],"We":[13,38],"prospectively":[14],"evaluated":[15],"if":[16],"a":[17,45,55,200],"qualitative":[18,46,127,146,190],"polymerase":[19],"chain":[20],"reaction":[21],"(PCR)":[22],"amplification":[23,48,129,148,192],"assay":[24,60,130,153,197],"virologic":[26,65],"could":[28],"maintain":[29],"accuracy":[30],"while":[31],"reducing":[32],"costs":[33],"in":[34,84],"Seoul,":[35,85],"South":[36,86],"Korea.":[37,87],"conducted":[39],"the":[40,108,145,150,161,194],"first":[41],"prospective":[42],"study":[43],"comparing":[44],"PCR":[47,59,128,147,164,191],"of":[49,67,90,114,144,149,171,193],"HIV-1":[50,151,195],"reverse":[51],"transcriptase":[52],"(RT)":[53],"versus":[54],"commercial":[56],"real":[57,162],"time":[58,163],"(i.e.,":[61],"viral":[62,110],"load)":[63],"150":[68,96,184],"patients":[69,97,185,206],"receiving":[70,98,207],"antiretroviral":[71],"therapy":[72],"(ART)":[73],"between":[74],"November":[75],"2011":[76],"and":[77,157,168,176,209],"August":[78],"2012":[79],"at":[80,165],"an":[81],"urban":[82],"hospital":[83],"A":[88],"total":[89],"215":[91,115],"blood":[92],"plasma":[93,117],"samples":[94,118,133],"from":[95],"ART":[99,208],"more":[101,120],"than":[102,121],"6":[103],"months":[104],"were":[105,154],"evaluated.":[106],"Using":[107],"individual":[109,132],"load":[111],"assay,":[112],"12":[113],"(5.6%)":[116],"had":[119],"500":[122],"RNA":[124,137,173],"copies/ml.":[125],"The":[126,142,189],"detected":[131],"with":[134,139],"\u2265500":[135],"copies/ml":[138],"100%":[140],"sensitivity.":[141],"specificities":[143],"RT":[152,196],"94.1%,":[155],"93.6%,":[156],"93.2%":[158],"compared":[159],"to":[160,203],"500,":[166],"1,000,":[167],"5,000":[169],"threshold":[170],"copies/ml,":[174],"respectively,":[175],"$24,940":[177],"USD":[178],"would":[179],"have":[180],"been":[181],"saved":[182],"during":[186],"10":[187],"months.":[188],"might":[198],"be":[199],"useful":[201],"approach":[202],"effectively":[204],"monitor":[205],"save":[210],"resources.":[211]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}