{"id":"https://openalex.org/W2137447263","doi":"https://doi.org/10.1210/en.2014-1448","title":"The Use of Protein-DNA, Chromatin Immunoprecipitation, and Transcriptome Arrays to Describe Transcriptional Circuits in the Dehydrated Male Rat Hypothalamus","display_name":"The Use of Protein-DNA, Chromatin Immunoprecipitation, and Transcriptome Arrays to Describe Transcriptional Circuits in the Dehydrated Male Rat Hypothalamus","publication_year":2014,"publication_date":"2014-08-21","ids":{"openalex":"https://openalex.org/W2137447263","doi":"https://doi.org/10.1210/en.2014-1448","mag":"2137447263","pmid":"https://pubmed.ncbi.nlm.nih.gov/25144923","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4256826"},"language":"en","primary_location":{"id":"doi:10.1210/en.2014-1448","doi":"https://doi.org/10.1210/en.2014-1448","is_oa":true,"landing_page_url":"https://doi.org/10.1210/en.2014-1448","pdf_url":null,"source":{"id":"https://openalex.org/S157527038","display_name":"Endocrinology","issn_l":"0013-7227","issn":["0013-7227","1945-7170"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1210/en.2014-1448","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Jing Qiu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jing Qiu","raw_affiliation_strings":["School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076844099","display_name":"Anna Kleineidam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anna Kleineidam","raw_affiliation_strings":["School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000714315","display_name":"Sabine S. Gouraud","orcid":"https://orcid.org/0000-0002-4917-0647","observed_orcids":["https://orcid.org/0000-0002-4917-0647"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sabine Gouraud","raw_affiliation_strings":["School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057765648","display_name":"Song Tieng Yao","orcid":"https://orcid.org/0000-0003-3337-4490","observed_orcids":["https://orcid.org/0000-0003-3337-4490"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Song Tieng Yao","raw_affiliation_strings":["School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003106813","display_name":"Mingkwan Greenwood","orcid":"https://orcid.org/0000-0003-0463-6615","observed_orcids":["https://orcid.org/0000-0003-0463-6615"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mingkwan Greenwood","raw_affiliation_strings":["School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082218345","display_name":"See-Ziau Hoe","orcid":"https://orcid.org/0000-0001-6138-1271","observed_orcids":["https://orcid.org/0000-0001-6138-1271"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"See Ziau Hoe","raw_affiliation_strings":["Department of Physiology (S.Z.H., C.H., D.M.), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology (S.Z.H., C.H., D.M.), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014747183","display_name":"Charles C.T. Hindmarch","orcid":"https://orcid.org/0000-0002-6036-1292","observed_orcids":["https://orcid.org/0000-0002-6036-1292"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB","MY"],"is_corresponding":false,"raw_author_name":"Charles Hindmarch","raw_affiliation_strings":["Department of Physiology (S.Z.H., C.H., D.M.), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia","School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology (S.Z.H., C.H., D.M.), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]},{"raw_affiliation_string":"School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044560051","display_name":"David Murphy","orcid":"https://orcid.org/0000-0003-2946-0353","observed_orcids":["https://orcid.org/0000-0003-2946-0353"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB","MY"],"is_corresponding":true,"raw_author_name":"David Murphy","raw_affiliation_strings":["Department of Physiology (S.Z.H., C.H., D.M.), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia","School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology (S.Z.H., C.H., D.M.), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]},{"raw_affiliation_string":"School of Clinical Sciences (J.Q., A.K., S.G., S.T.Y., M.G., C.H., D.M.), University of Bristol, Bristol BS1 3NY, United Kingdom","institution_ids":["https://openalex.org/I36234482"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5044560051"],"corresponding_institution_ids":["https://openalex.org/I33849332","https://openalex.org/I36234482"],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":{"value":4497,"currency":"EUR","value_usd":4850},"fwci":0.2082,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.44070798,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"155","issue":"11","first_page":"4380","last_page":"4390"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.7437000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.7437000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.04569999873638153,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11967","display_name":"Electrolyte and hormonal disorders","score":0.023399999365210533,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dehydration","display_name":"dehydration","score":0.8989999890327454},{"id":"https://openalex.org/keywords/supraoptic-nucleus","display_name":"supraoptic nucleus","score":0.8370000123977661},{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.9739999771118164},{"id":"https://openalex.org/keywords/vasopressin","display_name":"vasopressin","score":0.9869999885559082},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.640999972820282},{"id":"https://openalex.org/keywords/c-myc","display_name":"c-Myc","score":0.9750000238418579},{"id":"https://openalex.org/keywords/max","display_name":"Max","score":0.9509999752044678},{"id":"https://openalex.org/keywords/transcriptional-circuits","display_name":"transcriptional circuits","score":0.6779999732971191},{"id":"https://openalex.org/keywords/osmoregulation","display_name":"osmoregulation","score":0.6959999799728394},{"id":"https://openalex.org/keywords/c-myc-target-genes","display_name":"c-Myc target genes","score":0.8709999918937683},{"id":"https://openalex.org/keywords/slc7a5","display_name":"SLC7A5","score":0.8799999952316284},{"id":"https://openalex.org/keywords/hdac2","display_name":"HDAC2","score":0.871999979019165},{"id":"https://openalex.org/keywords/gene-expression-changes","display_name":"gene expression changes","score":0.4359999895095825}],"concepts":[{"id":"https://openalex.org/C134320426","wikidata":"https://www.wikidata.org/wiki/Q901026","display_name":"Chromatin immunoprecipitation","level":5,"score":0.749860405921936},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6733253002166748},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.6405074000358582},{"id":"https://openalex.org/C2776370428","wikidata":"https://www.wikidata.org/wiki/Q21124841","display_name":"Vasopressin","level":2,"score":0.5421558022499084},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4923897981643677},{"id":"https://openalex.org/C71829478","wikidata":"https://www.wikidata.org/wiki/Q901305","display_name":"Immunoprecipitation","level":3,"score":0.445239782333374},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.44168218970298767},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4261510968208313},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.38300830125808716},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.364172101020813},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3625384569168091},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.34596189856529236},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3031579256057739},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18486550450325012},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07612752914428711}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003681","descriptor_name":"Dehydration","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003681","descriptor_name":"Dehydration","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007031","descriptor_name":"Hypothalamus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007031","descriptor_name":"Hypothalamus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046228","descriptor_name":"Microarray Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D047369","descriptor_name":"Chromatin Immunoprecipitation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1210/en.2014-1448","doi":"https://doi.org/10.1210/en.2014-1448","is_oa":true,"landing_page_url":"https://doi.org/10.1210/en.2014-1448","pdf_url":null,"source":{"id":"https://openalex.org/S157527038","display_name":"Endocrinology","issn_l":"0013-7227","issn":["0013-7227","1945-7170"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3239825","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4256826","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:25144923","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25144923","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4256826","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4256826/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology","raw_type":"Text"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire_cris_publications/20c97b43-0c70-43fe-a560-6bff72834a1a","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/1983/20c97b43-0c70-43fe-a560-6bff72834a1a","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Qiu, J, Kleineidam, A, Gouraud, S, Yao, S T, Greenwood, M, Hoe, S Z, Hindmarch, C & Murphy, D 2014, 'The use of protein-DNA, chromatin immunoprecipitation, and transcriptome arrays to describe transcriptional circuits in the dehydrated male rat hypothalamus', Endocrinology, vol. 155, no. 11, pp. 4380-4390. https://doi.org/10.1210/en.2014-1448","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1210/en.2014-1448","doi":"https://doi.org/10.1210/en.2014-1448","is_oa":true,"landing_page_url":"https://doi.org/10.1210/en.2014-1448","pdf_url":null,"source":{"id":"https://openalex.org/S157527038","display_name":"Endocrinology","issn_l":"0013-7227","issn":["0013-7227","1945-7170"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrinology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2272521938","display_name":null,"funder_award_id":"BB/J01515/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G5070521980","display_name":"Bilateral BBSRC-FAPESP: Behavioural and neuroendocrine mechanisms regulating hydromineral homeostasis - a lifelong perspective","funder_award_id":"BB/J015415/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W11800597","https://openalex.org/W160919559","https://openalex.org/W190654828","https://openalex.org/W1491043075","https://openalex.org/W1516996751","https://openalex.org/W1535569785","https://openalex.org/W1586916519","https://openalex.org/W1766189871","https://openalex.org/W1900852307","https://openalex.org/W1912856651","https://openalex.org/W1964957214","https://openalex.org/W1967518744","https://openalex.org/W1969218281","https://openalex.org/W1972709515","https://openalex.org/W1981189185","https://openalex.org/W1983549737","https://openalex.org/W1988929415","https://openalex.org/W1990014142","https://openalex.org/W1996408189","https://openalex.org/W2004029499","https://openalex.org/W2006110610","https://openalex.org/W2011803470","https://openalex.org/W2012739670","https://openalex.org/W2021762952","https://openalex.org/W2024055501","https://openalex.org/W2025074445","https://openalex.org/W2025741887","https://openalex.org/W2027990429","https://openalex.org/W2030745039","https://openalex.org/W2035777673","https://openalex.org/W2040691279","https://openalex.org/W2045362835","https://openalex.org/W2047632234","https://openalex.org/W2048745420","https://openalex.org/W2050752504","https://openalex.org/W2051678425","https://openalex.org/W2055077534","https://openalex.org/W2062837316","https://openalex.org/W2065161623","https://openalex.org/W2071652062","https://openalex.org/W2077944067","https://openalex.org/W2081844604","https://openalex.org/W2082147251","https://openalex.org/W2082274307","https://openalex.org/W2083802827","https://openalex.org/W2089778796","https://openalex.org/W2103902627","https://openalex.org/W2107277218","https://openalex.org/W2114360920","https://openalex.org/W2120382629","https://openalex.org/W2121571711","https://openalex.org/W2126775879","https://openalex.org/W2127321901","https://openalex.org/W2127687960","https://openalex.org/W2131220396","https://openalex.org/W2132147998","https://openalex.org/W2135472547","https://openalex.org/W2140956142","https://openalex.org/W2157795344","https://openalex.org/W2404962226","https://openalex.org/W2485631234","https://openalex.org/W4294107304"],"related_works":["https://openalex.org/W152191955","https://openalex.org/W1967518744","https://openalex.org/W2103391553","https://openalex.org/W2097103529","https://openalex.org/W4256182611","https://openalex.org/W2070018914","https://openalex.org/W2082274307","https://openalex.org/W3174151504","https://openalex.org/W2127687960","https://openalex.org/W1808911324"],"abstract_inverted_index":{"The":[0],"supraoptic":[1],"nucleus":[2],"(SON)":[3],"of":[4,18,35,61,77,90,111,125,136],"the":[5,19,26,59,103,112,186,229,240,245,258],"hypothalamus":[6],"is":[7],"responsible":[8],"for":[9,100],"maintaining":[10],"osmotic":[11],"stability":[12],"in":[13,47,58,74,119,178,185,197,228],"mammals":[14],"through":[15],"its":[16],"elaboration":[17],"antidiuretic":[20],"hormone":[21],"arginine":[22,199],"vasopressin.":[23],"Upon":[24],"dehydration,":[25,189],"SON":[27,91,187,198,230],"undergoes":[28],"a":[29],"function-related":[30],"plasticity,":[31],"which":[32,52,68,126,243],"includes":[33],"remodeling":[34],"morphology,":[36],"electrical":[37],"properties,":[38],"and":[39,94,134,149,162,190,194,257],"biosynthetic":[40],"activity.":[41],"This":[42],"process":[43],"occurs":[44],"alongside":[45],"alterations":[46],"steady":[48],"state":[49],"transcript":[50],"levels,":[51],"might":[53,71],"be":[54,72],"mediated":[55],"by":[56,203],"changes":[57,118,227],"activity":[60],"transcription":[62,69,107,137,153],"factors.":[63],"In":[64],"order":[65],"to":[66,102,121,131,168],"identify":[67],"factors":[70],"involved":[73],"changing":[75],"patterns":[76],"gene":[78],"expression,":[79],"an":[80,176],"Affymetrix":[81],"protein-DNA":[82],"array":[83],"analysis":[84,115,172],"was":[85],"carried":[86],"out.":[87],"Nuclear":[88],"extracts":[89],"from":[92,208],"dehydrated":[93],"control":[95],"male":[96],"rats":[97],"were":[98],"analyzed":[99],"binding":[101,109,120,130],"345":[104],"consensus":[105,123],"DNA":[106],"factor":[108,146,154],"sequences":[110,156],"array.":[113],"Statistical":[114],"revealed":[116],"significant":[117],"26":[122],"elements,":[124],"EMSA":[127],"confirmed":[128],"increased":[129],"signal":[132],"transducer":[133],"activator":[135],"(Stat)":[138],"1/Stat3,":[139],"cellular":[140,143],"Myelocytomatosis":[141],"virus-like":[142],"proto-oncogene":[144,261],"(c-Myc)-Myc-associated":[145],"X":[147],"(Max),":[148],"pre-B":[150],"cell":[151],"leukemia":[152],"1":[155],"after":[157,188,231],"dehydration.":[158,232],"Focusing":[159],"on":[160],"c-Myc":[161,222,236],"Max,":[163,182],"we":[164,191,218],"used":[165],"quantitative":[166],"PCR":[167],"confirm":[169],"previous":[170],"transcriptomic":[171,216],"that":[173],"had":[174],"suggested":[175],"increase":[177],"c-Myc,":[179],"but":[180],"not":[181],"mRNA":[183],"levels":[184],"demonstrated":[192],"c-Myc-":[193],"Max-like":[195],"immunoreactivities":[196],"vasopressin-expressing":[200],"cells.":[201],"Finally,":[202],"comparing":[204],"new":[205],"data":[206],"obtained":[207],"Roche-NimbleGen":[209],"chromatin":[210],"immunoprecipitation":[211],"arrays":[212],"with":[213],"previously":[214],"published":[215],"data,":[217],"have":[219],"identified":[220],"putative":[221],"target":[223],"genes":[224],"whose":[225],"expression":[226],"These":[233],"include":[234],"known":[235],"targets,":[237],"such":[238],"as":[239],"Slc7a5":[241],"gene,":[242],"encodes":[244],"L-type":[246],"amino":[247],"acid":[248],"transporter":[249],"1,":[250],"ribosomal":[251],"protein":[252],"L24,":[253],"histone":[254],"deactylase":[255],"2,":[256],"Rat":[259],"sarcoma":[260],"(Ras)-related":[262],"nuclear":[263],"GTPase.":[264]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}