{"id":"https://openalex.org/W2137339787","doi":null,"title":"Adiponectin and leptin molecular actions and clinical significance in breast cancer.","display_name":"Adiponectin and leptin molecular actions and clinical significance in breast cancer.","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2137339787","mag":"2137339787","pmid":"https://pubmed.ncbi.nlm.nih.gov/24505549","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3913152"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:2900979","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3913152","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3913152","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058588083","display_name":"Mohan Reddy Nalabolu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405258880","display_name":"Mahavir Medical Research Centre","ror":"https://ror.org/01bgeev84","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4405258880"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mohan Reddy Nalabolu","raw_affiliation_strings":["Research Scholar, Bhagwan Mahavir Medical Research Center, Department of Genetics, Mahavir Marg, A.C.Guards, Hyderabad-500004, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Scholar, Bhagwan Mahavir Medical Research Center, Department of Genetics, Mahavir Marg, A.C.Guards, Hyderabad-500004, Andhra Pradesh, India","institution_ids":["https://openalex.org/I4405258880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083816847","display_name":"Kalyani Palasamudram","orcid":"https://orcid.org/0000-0002-9227-7378","observed_orcids":["https://orcid.org/0000-0002-9227-7378"]},"institutions":[{"id":"https://openalex.org/I4405258880","display_name":"Mahavir Medical Research Centre","ror":"https://ror.org/01bgeev84","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4405258880"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kalyani Palasamudram","raw_affiliation_strings":["Research Scholar, Bhagwan Mahavir Medical Research Center, Department of Genetics, Mahavir Marg, A.C.Guards, Hyderabad-500004, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Scholar, Bhagwan Mahavir Medical Research Center, Department of Genetics, Mahavir Marg, A.C.Guards, Hyderabad-500004, Andhra Pradesh, India","institution_ids":["https://openalex.org/I4405258880"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069483032","display_name":"Kaiser Jamil","orcid":"https://orcid.org/0000-0001-5442-3867","observed_orcids":["https://orcid.org/0000-0001-5442-3867"]},"institutions":[{"id":"https://openalex.org/I4405258880","display_name":"Mahavir Medical Research Centre","ror":"https://ror.org/01bgeev84","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4405258880"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kaiser Jamil","raw_affiliation_strings":["Research Scholar, Bhagwan Mahavir Medical Research Center, Department of Genetics, Mahavir Marg, A.C.Guards, Hyderabad-500004, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Scholar, Bhagwan Mahavir Medical Research Center, Department of Genetics, Mahavir Marg, A.C.Guards, Hyderabad-500004, Andhra Pradesh, India","institution_ids":["https://openalex.org/I4405258880"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4405258880"],"apc_list":null,"apc_paid":null,"fwci":4.5777,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.95371053,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"8","issue":"1","first_page":"31","last_page":"40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors","score":0.01860000006854534,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adiponectin","display_name":"adiponectin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":1.0},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9980000257492065},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.996999979019165},{"id":"https://openalex.org/keywords/postmenopausal-breast-cancer","display_name":"postmenopausal breast cancer","score":0.859000027179718},{"id":"https://openalex.org/keywords/adipose-tissue","display_name":"adipose tissue","score":0.9639999866485596},{"id":"https://openalex.org/keywords/energy-homeostasis","display_name":"energy homeostasis","score":0.9509999752044678},{"id":"https://openalex.org/keywords/insulin-sensitivity","display_name":"insulin sensitivity","score":0.8610000014305115},{"id":"https://openalex.org/keywords/adipogenic-differentiation","display_name":"adipogenesis","score":0.9639999866485596},{"id":"https://openalex.org/keywords/anti-inflammatory-pathways","display_name":"anti-inflammatory pathways","score":0.6990000009536743},{"id":"https://openalex.org/keywords/tumor-cell-proliferation","display_name":"tumor cell proliferation","score":0.6460000276565552}],"concepts":[{"id":"https://openalex.org/C2776782570","wikidata":"https://www.wikidata.org/wiki/Q357439","display_name":"Adiponectin","level":4,"score":0.9377427101135254},{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.9009695053100586},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7441298961639404},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.6644952297210693},{"id":"https://openalex.org/C194832188","wikidata":"https://www.wikidata.org/wiki/Q2638593","display_name":"Adipokine","level":4,"score":0.6507676839828491},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5900086760520935},{"id":"https://openalex.org/C2776175234","wikidata":"https://www.wikidata.org/wiki/Q357519","display_name":"Adipocyte","level":3,"score":0.5711817741394043},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5674769282341003},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5672821998596191},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4612535238265991},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.45392391085624695},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.3540395498275757},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3313808739185333}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:europepmc.org:2900979","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3913152","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:24505549","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24505549","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of hematology-oncology and stem cell research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3913152","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3913152/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Hematol Oncol Stem Cell Res","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:18a3463ae98040118ea02e1ff981c2fb","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/18a3463ae98040118ea02e1ff981c2fb","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Hematology-Oncology and Stem Cell Research, Vol 8, Iss 1 (2014)","raw_type":"article"},{"id":"mag:2137339787","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24505549","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2900979","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3913152","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W12645381","https://openalex.org/W87042221","https://openalex.org/W150064531","https://openalex.org/W183747983","https://openalex.org/W1570155932","https://openalex.org/W1631449371","https://openalex.org/W1866017223","https://openalex.org/W1879346051","https://openalex.org/W1886767677","https://openalex.org/W1967411366","https://openalex.org/W1970205234","https://openalex.org/W1973667176","https://openalex.org/W1976552085","https://openalex.org/W1984191109","https://openalex.org/W1984382912","https://openalex.org/W1986826247","https://openalex.org/W1992405425","https://openalex.org/W1997308909","https://openalex.org/W1997978122","https://openalex.org/W2001714670","https://openalex.org/W2011282245","https://openalex.org/W2014163208","https://openalex.org/W2016994959","https://openalex.org/W2018757636","https://openalex.org/W2022474551","https://openalex.org/W2031729449","https://openalex.org/W2036126766","https://openalex.org/W2038618315","https://openalex.org/W2040248629","https://openalex.org/W2042706232","https://openalex.org/W2043191787","https://openalex.org/W2043551756","https://openalex.org/W2045948521","https://openalex.org/W2047960581","https://openalex.org/W2048942491","https://openalex.org/W2050795981","https://openalex.org/W2052146004","https://openalex.org/W2055317878","https://openalex.org/W2058126433","https://openalex.org/W2062570379","https://openalex.org/W2065697164","https://openalex.org/W2068527957","https://openalex.org/W2069497802","https://openalex.org/W2076310317","https://openalex.org/W2077523349","https://openalex.org/W2080204015","https://openalex.org/W2083461110","https://openalex.org/W2088471199","https://openalex.org/W2091759162","https://openalex.org/W2093265805","https://openalex.org/W2094941511","https://openalex.org/W2095022880","https://openalex.org/W2105755425","https://openalex.org/W2109311297","https://openalex.org/W2113124347","https://openalex.org/W2118549419","https://openalex.org/W2118819459","https://openalex.org/W2120408896","https://openalex.org/W2123371309","https://openalex.org/W2124030977","https://openalex.org/W2126619151","https://openalex.org/W2127314379","https://openalex.org/W2127934772","https://openalex.org/W2131379009","https://openalex.org/W2132725893","https://openalex.org/W2132876215","https://openalex.org/W2134535786","https://openalex.org/W2136556119","https://openalex.org/W2138013274","https://openalex.org/W2138102988","https://openalex.org/W2145695837","https://openalex.org/W2150007763","https://openalex.org/W2151023302","https://openalex.org/W2152973392","https://openalex.org/W2153080496","https://openalex.org/W2153201988","https://openalex.org/W2154502881","https://openalex.org/W2158697993","https://openalex.org/W2161688306","https://openalex.org/W2163678936","https://openalex.org/W2167596697","https://openalex.org/W2168553115","https://openalex.org/W2273641847","https://openalex.org/W2317632943","https://openalex.org/W2356382349","https://openalex.org/W2412645772","https://openalex.org/W2623826512"],"related_works":["https://openalex.org/W2147929281","https://openalex.org/W1967799677","https://openalex.org/W1973993280","https://openalex.org/W2157795870","https://openalex.org/W1980183623","https://openalex.org/W2188489669","https://openalex.org/W2079714569","https://openalex.org/W2546806856","https://openalex.org/W1576793362","https://openalex.org/W4254006504"],"abstract_inverted_index":{"Obesity":[0],"is":[1,17],"an":[2],"important":[3],"public":[4],"health":[5],"problem":[6],"and":[7,35,41,45,65,70],"major":[8,19],"risk":[9],"factor":[10],"for":[11],"postmenopausal":[12],"breast":[13,54,73],"cancer.":[14,55,74],"Adipose":[15],"tissue":[16],"the":[18,23,26,36,62],"component":[20],"involved":[21,49],"in":[22,50,53,72],"control":[24],"of":[25,38,68],"metabolism":[27],"through":[28],"energy":[29],"homeostasis,":[30],"adipocyte":[31],"differentiation,":[32],"insulin":[33],"sensitivity":[34],"activation":[37],"anti-inflammatory":[39],"metabolic":[40],"immune":[42],"pathways.":[43],"Leptin":[44],"Adiponectin":[46],"pathways":[47],"are":[48],"proliferation":[51],"process":[52],"Current":[56],"review":[57],"describes":[58],"potential":[59],"relationship":[60],"between":[61],"molecular":[63],"actions":[64],"clinical":[66],"significance":[67],"leptin":[69],"adiponectin":[71]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
