{"id":"https://openalex.org/W2137309569","doi":"https://doi.org/10.1093/gerona/glp213","title":"Aging, Depot Origin, and Preadipocyte Gene Expression","display_name":"Aging, Depot Origin, and Preadipocyte Gene Expression","publication_year":2010,"publication_date":"2010-01-27","ids":{"openalex":"https://openalex.org/W2137309569","doi":"https://doi.org/10.1093/gerona/glp213","mag":"2137309569","pmid":"https://pubmed.ncbi.nlm.nih.gov/20106964","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2904595"},"language":"en","primary_location":{"id":"doi:10.1093/gerona/glp213","doi":"https://doi.org/10.1093/gerona/glp213","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gerona/glp213","pdf_url":"https://academic.oup.com/biomedgerontology/article-pdf/65A/3/242/16743105/glp213.pdf","source":{"id":"https://openalex.org/S969433497","display_name":"The Journals of Gerontology Series A","issn_l":"1079-5006","issn":["1079-5006","1758-535X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journals of Gerontology: Series A","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/biomedgerontology/article-pdf/65A/3/242/16743105/glp213.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Mark J. Cartwright","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark J. Cartwright","raw_affiliation_strings":["Department of Medicine, Boston University, Massachusetts, USA","Department of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Boston University, Massachusetts, USA","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Department of Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037111265","display_name":"Karen A. Schlauch","orcid":"https://orcid.org/0000-0001-6916-8571","observed_orcids":["https://orcid.org/0000-0001-6916-8571"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I134113660","display_name":"University of Nevada, Reno","ror":"https://ror.org/01keh0577","country_code":"US","type":"education","lineage":["https://openalex.org/I134113660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen Schlauch","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, University of Nevada, Reno","Department of Genetics and Genomics, Boston University, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, University of Nevada, Reno","institution_ids":["https://openalex.org/I134113660"]},{"raw_affiliation_string":"Department of Genetics and Genomics, Boston University, Massachusetts","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085351836","display_name":"Marc E. Lenburg","orcid":"https://orcid.org/0000-0002-5760-4708","observed_orcids":["https://orcid.org/0000-0002-5760-4708"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marc E. Lenburg","raw_affiliation_strings":["Department of Genetics and Genomics, Boston University, Massachusetts","Department of Pathology and Laboratory Medicine, Boston University, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Genomics, Boston University, Massachusetts","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Boston University, Massachusetts","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034798967","display_name":"Tamar Tchkonia","orcid":"https://orcid.org/0000-0003-4623-7145","observed_orcids":["https://orcid.org/0000-0003-4623-7145"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tamara Tchkonia","raw_affiliation_strings":["Department of Medicine","Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066152181","display_name":"Tamar Pirtskhalava","orcid":"https://orcid.org/0009-0007-5515-1091","observed_orcids":["https://orcid.org/0009-0007-5515-1091"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tamar Pirtskhalava","raw_affiliation_strings":["Department of Medicine","Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011268420","display_name":"Andrew Cartwright","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew Cartwright","raw_affiliation_strings":["Department of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015806576","display_name":"Thomas Thomou","orcid":"https://orcid.org/0000-0001-7154-3422","observed_orcids":["https://orcid.org/0000-0001-7154-3422"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Thomou","raw_affiliation_strings":["Department of Medicine","Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009102749","display_name":"James L. Kirkland","orcid":"https://orcid.org/0000-0003-1676-4905","observed_orcids":["https://orcid.org/0000-0003-1676-4905"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"James L. Kirkland","raw_affiliation_strings":["Department of Medicine","Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine","institution_ids":[]},{"raw_affiliation_string":"Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5009102749"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":4408,"currency":"USD","value_usd":4408},"apc_paid":{"value":4408,"currency":"USD","value_usd":4408},"fwci":4.0637,"has_fulltext":true,"cited_by_count":87,"citation_normalized_percentile":{"value":0.93869006,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"65A","issue":"3","first_page":"242","last_page":"251"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9458000063896179,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9458000063896179,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.040300000458955765,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.007300000172108412,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.8849999904632568},{"id":"https://openalex.org/keywords/preadipocytes","display_name":"preadipocytes","score":0.8709999918937683},{"id":"https://openalex.org/keywords/adipose-tissue-depots","display_name":"adipose tissue depots","score":0.7910000085830688},{"id":"https://openalex.org/keywords/epididymal-white-adipose-tissue","display_name":"epididymal adipose tissue","score":0.847000002861023},{"id":"https://openalex.org/keywords/perirenal-fat","display_name":"perirenal fat","score":0.9980000257492065},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.7630000114440918},{"id":"https://openalex.org/keywords/body-fat-distribution","display_name":"body fat distribution","score":0.6620000004768372},{"id":"https://openalex.org/keywords/adipogenic-differentiation","display_name":"adipogenesis","score":0.8769999742507935},{"id":"https://openalex.org/keywords/adipocyte-turnover","display_name":"adipocyte turnover","score":0.6769999861717224},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8299999833106995},{"id":"https://openalex.org/keywords/stress-response","display_name":"stress response","score":0.5180000066757202},{"id":"https://openalex.org/keywords/adipose-tissue-dysfunction","display_name":"adipose tissue dysfunction","score":0.5730000138282776}],"concepts":[{"id":"https://openalex.org/C122927707","wikidata":"https://www.wikidata.org/wiki/Q2824461","display_name":"Adipogenesis","level":3,"score":0.8646597266197205},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.625072717666626},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5960164070129395},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5950580835342407},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5459541082382202},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.5411332249641418},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5244964957237244},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.48409950733184814},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4173153042793274},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.30020856857299805},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.216909259557724},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.20222094655036926},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1855316162109375},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.12789449095726013}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008868","descriptor_name":"Microtubule Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D037181","descriptor_name":"Lectins, C-Type","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D037181","descriptor_name":"Lectins, C-Type","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D050218","descriptor_name":"Body Fat Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/gerona/glp213","doi":"https://doi.org/10.1093/gerona/glp213","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gerona/glp213","pdf_url":"https://academic.oup.com/biomedgerontology/article-pdf/65A/3/242/16743105/glp213.pdf","source":{"id":"https://openalex.org/S969433497","display_name":"The Journals of Gerontology Series A","issn_l":"1079-5006","issn":["1079-5006","1758-535X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journals of Gerontology: Series A","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2904595","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2904595","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Gerontol A Biol Sci Med Sci","raw_type":"Text"},{"id":"pmid:20106964","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20106964","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journals of gerontology. Series A, Biological sciences and medical sciences","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1093/gerona/glp213","doi":"https://doi.org/10.1093/gerona/glp213","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gerona/glp213","pdf_url":"https://academic.oup.com/biomedgerontology/article-pdf/65A/3/242/16743105/glp213.pdf","source":{"id":"https://openalex.org/S969433497","display_name":"The Journals of Gerontology Series A","issn_l":"1079-5006","issn":["1079-5006","1758-535X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journals of Gerontology: Series A","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[{"id":"https://openalex.org/G482663181","display_name":null,"funder_award_id":"AG 13925","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6454321031","display_name":"Effect of Aging on Preadipocyte Differentiation","funder_award_id":"R01AG013925","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320317043","display_name":"Noaber Foundation","ror":"https://ror.org/04e1ssa40"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2137309569.pdf","grobid_xml":"https://content.openalex.org/works/W2137309569.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W16294480","https://openalex.org/W114678641","https://openalex.org/W1578848510","https://openalex.org/W1680310998","https://openalex.org/W1935070596","https://openalex.org/W1964206888","https://openalex.org/W1979787322","https://openalex.org/W1989020172","https://openalex.org/W1998387866","https://openalex.org/W1999912466","https://openalex.org/W2003699850","https://openalex.org/W2011556759","https://openalex.org/W2013966513","https://openalex.org/W2017264236","https://openalex.org/W2021765303","https://openalex.org/W2022487205","https://openalex.org/W2023271280","https://openalex.org/W2024030143","https://openalex.org/W2033553111","https://openalex.org/W2048101387","https://openalex.org/W2049986736","https://openalex.org/W2060449981","https://openalex.org/W2078966733","https://openalex.org/W2081098333","https://openalex.org/W2082463577","https://openalex.org/W2082619868","https://openalex.org/W2085129416","https://openalex.org/W2089022581","https://openalex.org/W2089783517","https://openalex.org/W2090501685","https://openalex.org/W2092746889","https://openalex.org/W2093897492","https://openalex.org/W2106613328","https://openalex.org/W2109972881","https://openalex.org/W2110065044","https://openalex.org/W2111177772","https://openalex.org/W2112024733","https://openalex.org/W2126678219","https://openalex.org/W2131052962","https://openalex.org/W2140508742","https://openalex.org/W2140727482","https://openalex.org/W2140886368","https://openalex.org/W2141054938","https://openalex.org/W2142755685","https://openalex.org/W2151115776","https://openalex.org/W2155853807","https://openalex.org/W2164220875","https://openalex.org/W2171425285","https://openalex.org/W2293358169","https://openalex.org/W2330281772","https://openalex.org/W2333778403","https://openalex.org/W2335728918","https://openalex.org/W2399182525","https://openalex.org/W4243824705"],"related_works":["https://openalex.org/W2013966513","https://openalex.org/W2064218107","https://openalex.org/W2051770547","https://openalex.org/W2330281772","https://openalex.org/W2017264236","https://openalex.org/W2140727482","https://openalex.org/W2058902172","https://openalex.org/W2399182525","https://openalex.org/W7097104520","https://openalex.org/W7097790270"],"abstract_inverted_index":{"Fat":[0],"distribution":[1],"changes":[2,6,117,138],"with":[3,54,72,92,99,109,126],"aging.":[4],"Inherent":[5],"in":[7,27,76,103,113,120,129,133,139],"fat":[8,14,114,149],"cell":[9],"progenitors":[10],"may":[11],"contribute":[12],"because":[13],"cells":[15],"turn":[16],"over":[17],"throughout":[18],"life.":[19],"To":[20],"define":[21],"mechanisms,":[22],"gene":[23,141],"expression":[24,142],"was":[25],"profiled":[26],"preadipocytes":[28,77],"cultured":[29],"from":[30,78],"epididymal":[31,123],"and":[32,37,82,97,106,131,151],"perirenal":[33,121,134],"depots":[34],"of":[35,41],"young":[36],"old":[38,83],"rats.":[39],"8.4%":[40],"probe":[42],"sets":[43],"differed":[44,53],"significantly":[45,91],"between":[46],"depots,":[47,96,145],"particularly":[48],"developmental":[49],"genes.":[50],"Only":[51],"0.02%":[52],"aging,":[55,93,110],"despite":[56],"using":[57],"less":[58],"stringent":[59],"criteria":[60],"than":[61,122],"for":[62],"comparing":[63],"depots.":[64],"Twenty-five":[65],"genes":[66],"selected":[67],"based":[68],"on":[69],"fold":[70],"change":[71],"aging":[73],"were":[74,118],"analyzed":[75],"additional":[79],"young,":[80],"middle-aged,":[81],"animals":[84],"by":[85],"polymerase":[86],"chain":[87],"reaction.":[88],"Thirteen":[89],"changed":[90,108],"13":[94],"among":[95,144],"9":[98],"both.":[100],"Genes":[101],"involved":[102],"inflammation,":[104],"stress,":[105],"differentiation":[107],"as":[111],"occurs":[112],"tissue.":[115],"Age-related":[116],"greater":[119],"preadipocytes,":[124],"consistent":[125],"larger":[127],"declines":[128],"replication":[130],"adipogenesis":[132],"preadipocytes.":[135],"Thus,":[136],"age-related":[137],"preadipocyte":[140],"differ":[143],"potentially":[146],"contributing":[147],"to":[148],"redistribution":[150],"dysfunction.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}