{"id":"https://openalex.org/W2137195441","doi":"https://doi.org/10.1126/science.1237439","title":"The Long-Term Stability of the Human Gut Microbiota","display_name":"The Long-Term Stability of the Human Gut Microbiota","publication_year":2013,"publication_date":"2013-07-04","ids":{"openalex":"https://openalex.org/W2137195441","doi":"https://doi.org/10.1126/science.1237439","mag":"2137195441","pmid":"https://pubmed.ncbi.nlm.nih.gov/23828941","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3791589"},"language":"en","primary_location":{"id":"doi:10.1126/science.1237439","doi":"https://doi.org/10.1126/science.1237439","is_oa":false,"landing_page_url":"https://doi.org/10.1126/science.1237439","pdf_url":null,"source":{"id":"https://openalex.org/S3880285","display_name":"Science","issn_l":"0036-8075","issn":["0036-8075","0193-4511","1095-9203"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315823","host_organization_name":"American Association for the Advancement of Science","host_organization_lineage":["https://openalex.org/P4310315823"],"host_organization_lineage_names":["American Association for the Advancement of Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3791589","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049350088","display_name":"Jeremiah J. Faith","orcid":"https://orcid.org/0000-0002-2691-4500","observed_orcids":["https://orcid.org/0000-0002-2691-4500"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremiah J. Faith","raw_affiliation_strings":["Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084763572","display_name":"Janaki L. Guruge","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janaki L. Guruge","raw_affiliation_strings":["Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053831021","display_name":"Mark R. Charbonneau","orcid":"https://orcid.org/0000-0003-4893-8244","observed_orcids":["https://orcid.org/0000-0003-4893-8244"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Charbonneau","raw_affiliation_strings":["Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052504918","display_name":"Sathish Subramanian","orcid":"https://orcid.org/0000-0002-4341-8592","observed_orcids":["https://orcid.org/0000-0002-4341-8592"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sathish Subramanian","raw_affiliation_strings":["Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065109434","display_name":"Henning Seedorf","orcid":"https://orcid.org/0000-0002-5763-0236","observed_orcids":["https://orcid.org/0000-0002-5763-0236"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Henning Seedorf","raw_affiliation_strings":["Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072088715","display_name":"Andrew L. Goodman","orcid":"https://orcid.org/0000-0001-7599-3471","observed_orcids":["https://orcid.org/0000-0001-7599-3471"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew L. Goodman","raw_affiliation_strings":["Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049747447","display_name":"Jos\u00e9 C. Clemente","orcid":"https://orcid.org/0000-0002-3970-9856","observed_orcids":["https://orcid.org/0000-0002-3970-9856"]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jose C. Clemente","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309, USA","institution_ids":["https://openalex.org/I188538660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033881627","display_name":"Rob D. Knight","orcid":"https://orcid.org/0000-0002-0975-9019","observed_orcids":["https://orcid.org/0000-0002-0975-9019","https://orcid.org/0000-0001-7531-0087"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rob Knight","raw_affiliation_strings":["Biofrontiers Institute, University of Colorado, Boulder, CO 80309, USA","Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309, USA","Howard Hughes Medical Institute, University of Colorado, Boulder, CO 80309, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biofrontiers Institute, University of Colorado, Boulder, CO 80309, USA","institution_ids":["https://openalex.org/I188538660"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309, USA","institution_ids":["https://openalex.org/I188538660"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, University of Colorado, Boulder, CO 80309, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I188538660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100686019","display_name":"Andrew C. Heath","orcid":"https://orcid.org/0000-0002-9414-6857","observed_orcids":["https://orcid.org/0000-0002-9414-6857"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew C. Heath","raw_affiliation_strings":["Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005825467","display_name":"Rudolph L. Leibel","orcid":"https://orcid.org/0000-0002-6062-7222","observed_orcids":["https://orcid.org/0000-0002-6062-7222"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rudolph L. Leibel","raw_affiliation_strings":["Departments of Pediatrics and Medicine, Division of Molecular Genetics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Medicine, Division of Molecular Genetics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027291163","display_name":"MICHAEL S. ROSENBAUM","orcid":"https://orcid.org/0000-0003-2835-9202","observed_orcids":["https://orcid.org/0000-0003-2835-9202"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Rosenbaum","raw_affiliation_strings":["Departments of Pediatrics and Medicine, Division of Molecular Genetics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Medicine, Division of Molecular Genetics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063884903","display_name":"Jeffrey I. Gordon","orcid":"https://orcid.org/0000-0001-8304-3548","observed_orcids":["https://orcid.org/0000-0001-8304-3548"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jeffrey I. Gordon","raw_affiliation_strings":["Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5063884903"],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":null,"apc_paid":null,"fwci":51.6034,"has_fulltext":false,"cited_by_count":2028,"citation_normalized_percentile":{"value":0.99941143,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"341","issue":"6141","first_page":"1237439","last_page":"1237439"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11791","display_name":"Microbial Community Ecology and Physiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9100000262260437},{"id":"https://openalex.org/keywords/microbiota-stability","display_name":"microbiome stability","score":0.7710000276565552},{"id":"https://openalex.org/keywords/power-law-distribution","display_name":"power-law distribution","score":0.5920000076293945},{"id":"https://openalex.org/keywords/fecal-microbiota","display_name":"fecal microbiota","score":0.8059999942779541},{"id":"https://openalex.org/keywords/liquid-diet","display_name":"liquid diet","score":0.6949999928474426},{"id":"https://openalex.org/keywords/body-weight","display_name":"body weight","score":0.7789999842643738},{"id":"https://openalex.org/keywords/16s-rrna-amplicon-sequencing","display_name":"16S rRNA amplicon sequencing","score":0.9120000004768372}],"concepts":[{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.7701165080070496},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.602969229221344},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.5495867729187012},{"id":"https://openalex.org/C2987857752","wikidata":"https://www.wikidata.org/wiki/Q12147","display_name":"Human health","level":2,"score":0.4837663173675537},{"id":"https://openalex.org/C2992479659","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut bacteria","level":3,"score":0.448047935962677},{"id":"https://openalex.org/C91478284","wikidata":"https://www.wikidata.org/wiki/Q6623796","display_name":"Human microbiome","level":3,"score":0.44792601466178894},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4420406222343445},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.2826753258705139},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.21241259574890137},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19659322500228882},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15014144778251648},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.09687003493309021}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005190","descriptor_name":"Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D031204","descriptor_name":"Caloric Restriction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041981","descriptor_name":"Gastrointestinal Tract","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D042822","descriptor_name":"Genomic Instability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1126/science.1237439","doi":"https://doi.org/10.1126/science.1237439","is_oa":false,"landing_page_url":"https://doi.org/10.1126/science.1237439","pdf_url":null,"source":{"id":"https://openalex.org/S3880285","display_name":"Science","issn_l":"0036-8075","issn":["0036-8075","0193-4511","1095-9203"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315823","host_organization_name":"American Association for the Advancement of Science","host_organization_lineage":["https://openalex.org/P4310315823"],"host_organization_lineage_names":["American Association for the Advancement of Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science","raw_type":"journal-article"},{"id":"pmid:23828941","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23828941","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science (New York, N.Y.)","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2868953","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3791589","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3791589","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3791589","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Science","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1009.177","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1009.177","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://science.sciencemag.org/content/sci/341/6141/1237439.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2868953","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3791589","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1215869453","display_name":"Genomic and metabolomic foundations of human-microbial symbiosis in the gut","funder_award_id":"R37DK030292","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G1844854713","display_name":null,"funder_award_id":"DK-30292","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2004565107","display_name":null,"funder_award_id":"DK078669","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2650954989","display_name":"GENE-ENVIRONMENT INTERPLAY IN ALCOHOLISM","funder_award_id":"K05AA017688","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G3033189338","display_name":"Metagenomic Studies of the Gut Microbiomes of Obese and Lean Twins","funder_award_id":"P01DK078669","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3408939335","display_name":"Leptin in Human Energy and Neuroendocrine Homeostasis","funder_award_id":"R01DK064773","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G670796516","display_name":null,"funder_award_id":"DK 70977","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G7795604221","display_name":null,"funder_award_id":"DK64774","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G7868418976","display_name":"Characterizing the dynamic operations of model human gut communities in gnotobiotic mice and piglets","funder_award_id":"R01DK070977","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G8079444471","display_name":"Clinical and Translational Science Award","funder_award_id":"UL1TR000040","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000867824","display_name":"New York Obesity Research Center","funder_award_id":"P30DK026687","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000875002","display_name":"Genomic and metabolomic foundations of human-microbial symbiosis in the gut","funder_award_id":"R01DK030292","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"},{"id":"https://openalex.org/F4320312926","display_name":"Crohn's and Colitis Foundation","ror":"https://ror.org/05f2xbq60"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1950634808","https://openalex.org/W1963890672","https://openalex.org/W1982827785","https://openalex.org/W1984474722","https://openalex.org/W1989889539","https://openalex.org/W1993893394","https://openalex.org/W1997484087","https://openalex.org/W2002170378","https://openalex.org/W2016966302","https://openalex.org/W2041677964","https://openalex.org/W2051163560","https://openalex.org/W2082464084","https://openalex.org/W2095158284","https://openalex.org/W2095885321","https://openalex.org/W2098386120","https://openalex.org/W2098991824","https://openalex.org/W2107282968","https://openalex.org/W2109453886","https://openalex.org/W2112874908","https://openalex.org/W2113000633","https://openalex.org/W2122007620","https://openalex.org/W2122414480","https://openalex.org/W2122571005","https://openalex.org/W2124351063","https://openalex.org/W2124985265","https://openalex.org/W2125826054","https://openalex.org/W2126218947","https://openalex.org/W2128769815","https://openalex.org/W2136506752","https://openalex.org/W2146868985","https://openalex.org/W2149017136","https://openalex.org/W2149573313","https://openalex.org/W2151372451","https://openalex.org/W2152885278","https://openalex.org/W2157107905","https://openalex.org/W2163185640","https://openalex.org/W2163576465","https://openalex.org/W2166171121","https://openalex.org/W2169330513","https://openalex.org/W2316534927"],"related_works":["https://openalex.org/W2001688125","https://openalex.org/W3152171186","https://openalex.org/W2081132669","https://openalex.org/W2082900248","https://openalex.org/W2098991824","https://openalex.org/W2978748171","https://openalex.org/W4404301286","https://openalex.org/W4210816586","https://openalex.org/W4312181074","https://openalex.org/W7151564162"],"abstract_inverted_index":{"A":[0],"low-error":[1],"16S":[2],"ribosomal":[3],"RNA":[4],"amplicon":[5],"sequencing":[6,12],"method,":[7],"in":[8,24,51,87,95,100],"combination":[9,104],"with":[10],"whole-genome":[11],"of":[13,28,71,105,115],">500":[14],"cultured":[15],"isolates,":[16],"was":[17],"used":[18],"to":[19,35,81,109],"characterize":[20],"bacterial":[21],"strain":[22,88],"composition":[23,89],"the":[25,113,116],"fecal":[26],"microbiota":[27,118],"37":[29],"U.S.":[30],"adults":[31],"sampled":[32],"for":[33,56,79],"up":[34,80],"5":[36],"years.":[37],"Microbiota":[38],"stability":[39,106],"followed":[40],"a":[41,75,120],"power-law":[42],"function,":[43],"which":[44],"when":[45],"extrapolated":[46],"suggests":[47],"that":[48,85],"most":[49],"strains":[50,59],"an":[52],"individual":[53],"are":[54],"residents":[55],"decades.":[57],"Shared":[58],"were":[60,90],"recovered":[61],"from":[62,67],"family":[63],"members":[64],"but":[65],"not":[66],"unrelated":[68],"individuals.":[69],"Sampling":[70],"individuals":[72],"who":[73],"consumed":[74],"monotonous":[76],"liquid":[77],"diet":[78],"32":[82],"weeks":[83],"indicated":[84],"changes":[86,94],"better":[91],"predicted":[92],"by":[93,98],"weight":[96],"than":[97],"differences":[99],"sampling":[101],"interval.":[102],"This":[103],"and":[107,123],"responsiveness":[108],"physiologic":[110],"change":[111],"confirms":[112],"potential":[114],"gut":[117],"as":[119],"diagnostic":[121],"tool":[122],"therapeutic":[124],"target.":[125]},"counts_by_year":[{"year":2026,"cited_by_count":109},{"year":2025,"cited_by_count":115},{"year":2024,"cited_by_count":134},{"year":2023,"cited_by_count":173},{"year":2022,"cited_by_count":188},{"year":2021,"cited_by_count":218},{"year":2020,"cited_by_count":188},{"year":2019,"cited_by_count":186},{"year":2018,"cited_by_count":153},{"year":2017,"cited_by_count":152},{"year":2016,"cited_by_count":137},{"year":2015,"cited_by_count":147},{"year":2014,"cited_by_count":102},{"year":2013,"cited_by_count":25}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}