{"id":"https://openalex.org/W2136993987","doi":"https://doi.org/10.1258/095646207780658827","title":"Evaluation of the fluorescent treponemal antibody absorption test for detection of antibodies (immunoglobulins G and M) to Treponema pallidum in serologic diagnosis of syphilis","display_name":"Evaluation of the fluorescent treponemal antibody absorption test for detection of antibodies (immunoglobulins G and M) to Treponema pallidum in serologic diagnosis of syphilis","publication_year":2007,"publication_date":"2007-04-01","ids":{"openalex":"https://openalex.org/W2136993987","doi":"https://doi.org/10.1258/095646207780658827","mag":"2136993987","pmid":"https://pubmed.ncbi.nlm.nih.gov/17509177"},"language":"en","primary_location":{"id":"doi:10.1258/095646207780658827","doi":"https://doi.org/10.1258/095646207780658827","is_oa":false,"landing_page_url":"https://doi.org/10.1258/095646207780658827","pdf_url":null,"source":{"id":"https://openalex.org/S30045969","display_name":"International Journal of STD & AIDS","issn_l":"0956-4624","issn":["0956-4624","1758-1052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of STD & AIDS","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011337948","display_name":"G\u00fclseren Akta\u015f","orcid":"https://orcid.org/0000-0002-1611-5289","observed_orcids":["https://orcid.org/0000-0002-1611-5289"]},"institutions":[{"id":"https://openalex.org/I67581229","display_name":"Istanbul University","ror":"https://ror.org/03a5qrr21","country_code":"TR","type":"education","lineage":["https://openalex.org/I67581229"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Gulseren Aktas","raw_affiliation_strings":["Department of Microbiology and Clinical Microbiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Clinical Microbiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey","institution_ids":["https://openalex.org/I67581229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113778968","display_name":"Hugh D. Young","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802789809","display_name":"Edinburgh Royal Infirmary","ror":"https://ror.org/009bsy196","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802789809"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hugh Young","raw_affiliation_strings":["Department of Laboratory Medicine (Medical Microbiology), Edinburgh Royal Infirmary, Edinburgh, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine (Medical Microbiology), Edinburgh Royal Infirmary, Edinburgh, UK","institution_ids":["https://openalex.org/I2802789809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087476528","display_name":"Alex Moyes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802789809","display_name":"Edinburgh Royal Infirmary","ror":"https://ror.org/009bsy196","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802789809"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alex Moyes","raw_affiliation_strings":["Department of Laboratory Medicine (Medical Microbiology), Edinburgh Royal Infirmary, Edinburgh, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine (Medical Microbiology), Edinburgh Royal Infirmary, Edinburgh, UK","institution_ids":["https://openalex.org/I2802789809"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103049921","display_name":"Selim Badur","orcid":"https://orcid.org/0000-0002-1316-6259","observed_orcids":["https://orcid.org/0000-0002-1316-6259"]},"institutions":[{"id":"https://openalex.org/I67581229","display_name":"Istanbul University","ror":"https://ror.org/03a5qrr21","country_code":"TR","type":"education","lineage":["https://openalex.org/I67581229"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Selim Badur","raw_affiliation_strings":["Department of Microbiology and Clinical Microbiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Clinical Microbiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey","institution_ids":["https://openalex.org/I67581229"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":0.2152,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.61396037,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"18","issue":"4","first_page":"255","last_page":"260"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11934","display_name":"Syphilis Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11934","display_name":"Syphilis Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10296","display_name":"Vector-borne infectious diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/syphilis","display_name":"syphilis","score":0.7559999823570251},{"id":"https://openalex.org/keywords/treponema-pallidum","display_name":"Treponema pallidum","score":0.9819999933242798},{"id":"https://openalex.org/keywords/fluorescent-treponemal-antibody-absorption-test","display_name":"fluorescent treponemal antibody absorption test","score":0.9200000166893005},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.7450000047683716},{"id":"https://openalex.org/keywords/treponema-pallidum-hemagglutination-assay","display_name":"TPHA","score":0.9330000281333923},{"id":"https://openalex.org/keywords/treponema-pallidum-particle-agglutination-assay","display_name":"Treponema pallidum particle agglutination assay","score":0.9539999961853027},{"id":"https://openalex.org/keywords/western-blot","display_name":"Western blot","score":0.765999972820282},{"id":"https://openalex.org/keywords/confirmatory-serology","display_name":"confirmatory serology","score":0.5640000104904175},{"id":"https://openalex.org/keywords/igg-and-igm-antibodies","display_name":"IgM and IgG antibodies","score":0.7480000257492065},{"id":"https://openalex.org/keywords/false-negative-results","display_name":"false-negative results","score":0.640999972820282}],"concepts":[{"id":"https://openalex.org/C2776687281","wikidata":"https://www.wikidata.org/wiki/Q7294218","display_name":"Rapid plasma reagin","level":5,"score":0.9174169301986694},{"id":"https://openalex.org/C2776983459","wikidata":"https://www.wikidata.org/wiki/Q41083","display_name":"Syphilis","level":3,"score":0.8636373281478882},{"id":"https://openalex.org/C2780187896","wikidata":"https://www.wikidata.org/wiki/Q134745","display_name":"Treponema","level":4,"score":0.8460840582847595},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.7443211078643799},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6286157965660095},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.60133296251297},{"id":"https://openalex.org/C2908804808","wikidata":"https://www.wikidata.org/wiki/Q41083","display_name":"Syphilis Serodiagnosis","level":4,"score":0.5228571891784668},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.47144782543182373},{"id":"https://openalex.org/C34343649","wikidata":"https://www.wikidata.org/wiki/Q1548862","display_name":"Hemagglutination","level":3,"score":0.44413483142852783},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3598778545856476},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005188","descriptor_name":"False Negative Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006385","descriptor_name":"Hemagglutination Inhibition Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D007075","descriptor_name":"Immunoglobulin M","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D011933","descriptor_name":"Reagent Kits, Diagnostic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013587","descriptor_name":"Syphilis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D013588","descriptor_name":"Syphilis Serodiagnosis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016508","descriptor_name":"Fluorescent Treponemal Antibody-Absorption Test","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1258/095646207780658827","doi":"https://doi.org/10.1258/095646207780658827","is_oa":false,"landing_page_url":"https://doi.org/10.1258/095646207780658827","pdf_url":null,"source":{"id":"https://openalex.org/S30045969","display_name":"International Journal of STD & AIDS","issn_l":"0956-4624","issn":["0956-4624","1758-1052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of STD & AIDS","raw_type":"journal-article"},{"id":"pmid:17509177","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17509177","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of STD & AIDS","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2388852803","https://openalex.org/W2419675874","https://openalex.org/W1938520473","https://openalex.org/W4245462958","https://openalex.org/W2025505277","https://openalex.org/W2888574094","https://openalex.org/W7125768277","https://openalex.org/W2394740948","https://openalex.org/W2417799712","https://openalex.org/W2140493887"],"abstract_inverted_index":{"We":[0],"compared":[1],"the":[2,13,20,27,36,47,64,78,89,100,103,106,109,113,127],"fluorescent":[3],"treponemal":[4,92],"antibody-absorption":[5],"(FTA-ABS)":[6],"(immunoglobulin":[7],"(Ig)G":[8],"+":[9],"IgM)":[10],"assay":[11,18,25,34,51],"with":[12,60,102],"(micro-)":[14],"Treponema":[15],"pallidum":[16,22],"haemagglutination":[17],"(TPHA),":[19],"T.":[21],"particle":[23],"agglutination":[24],"(TPPA),":[26],"Murex":[28],"syphilis":[29,147],"ICE":[30,110],"(ICE)":[31],"enzyme-linked":[32],"immunosorbent":[33],"(ELISA),":[35],"Diesse":[37],"Enzywell":[38],"TP":[39,114],"(TP)":[40],"(ELISA)":[41,68],"using":[42,52,94],"122":[43],"serum":[44,54],"samples":[45,55],"and":[46,88,112,120,151],"Western":[48],"blot":[49],"(WB)":[50],"42":[53],"whose":[56],"results":[57,124,153],"were":[58,69,116],"inharmonious":[59],"other":[61],"tests.":[62,97],"Additionally,":[63],"Captia":[65],"syphilis-M":[66],"(IgM)":[67],"performed.":[70],"All":[71],"sera":[72],"had":[73],"already":[74],"been":[75],"examined":[76],"by":[77,148],"rapid":[79],"plasma":[80],"reagin":[81],"(RPR)":[82],"card":[83],"test,":[84,105,108,134],"a":[85,91,131,140],"non-treponemal":[86],"test":[87,93,111,115,129,142],"TPHA,":[90],"routine":[95],"screening":[96],"Agreements":[98],"of":[99,146],"FTA-ABS":[101,128],"TPHA":[104],"TPPA":[107],"97.5%,":[117],"95.9%,":[118],"98.3%":[119],"98.3%,":[121],"respectively.":[122],"The":[123],"suggest":[125],"that":[126],"is":[130],"useful":[132],"confirmatory":[133,141],"but":[135],"can":[136],"be":[137],"inadequate":[138],"as":[139],"for":[143],"serologic":[144],"diagnosis":[145],"giving":[149],"equivocal":[150],"false-negative":[152],"even":[154],"rarely.":[155]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}