{"id":"https://openalex.org/W2136934360","doi":"https://doi.org/10.1186/bcr3394","title":"Premenopausal endogenous steroid hormones and breast cancer risk: results from the Nurses' Health Study II","display_name":"Premenopausal endogenous steroid hormones and breast cancer risk: results from the Nurses' Health Study II","publication_year":2013,"publication_date":"2013-03-06","ids":{"openalex":"https://openalex.org/W2136934360","doi":"https://doi.org/10.1186/bcr3394","mag":"2136934360","pmid":"https://pubmed.ncbi.nlm.nih.gov/23497468","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3672790"},"language":"en","primary_location":{"id":"doi:10.1186/bcr3394","doi":"https://doi.org/10.1186/bcr3394","is_oa":true,"landing_page_url":"https://doi.org/10.1186/bcr3394","pdf_url":"https://breast-cancer-research.biomedcentral.com/counter/pdf/10.1186/bcr3394","source":{"id":"https://openalex.org/S42140187","display_name":"Breast Cancer Research","issn_l":"1465-5411","issn":["1465-5411","1465-542X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Breast Cancer Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://breast-cancer-research.biomedcentral.com/counter/pdf/10.1186/bcr3394","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059302865","display_name":"Ren\u00e9e T. Fortner","orcid":"https://orcid.org/0000-0002-1426-8505","observed_orcids":["https://orcid.org/0000-0002-1426-8505"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ren\u00e9e T Fortner","raw_affiliation_strings":["Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Ave., Boston, MA, 02115, USA","Harvard School of Public Health, 677 Huntington Ave, Boston, MA, 2115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Ave., Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Harvard School of Public Health, 677 Huntington Ave, Boston, MA, 2115, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014551852","display_name":"A. Heather Eliassen","orcid":"https://orcid.org/0000-0002-3961-6609","observed_orcids":["https://orcid.org/0000-0002-3961-6609"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A Heather Eliassen","raw_affiliation_strings":["Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Ave., Boston, MA, 02115, USA","Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA","Harvard School of Public Health, 677 Huntington Ave, Boston, MA, 2115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Ave., Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard School of Public Health, 677 Huntington Ave, Boston, MA, 2115, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067206764","display_name":"Donna L. Spiegelman","orcid":"https://orcid.org/0000-0003-4006-4650","observed_orcids":["https://orcid.org/0000-0003-4006-4650"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donna Spiegelman","raw_affiliation_strings":["Harvard School of Public Health, 677 Huntington Ave, Boston, MA, 2115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard School of Public Health, 677 Huntington Ave, Boston, MA, 2115, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083991449","display_name":"Walter Churchill Willett","orcid":"https://orcid.org/0000-0003-1458-7597","observed_orcids":["https://orcid.org/0000-0003-1458-7597"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Walter C Willett","raw_affiliation_strings":["Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Ave., Boston, MA, 02115, USA","Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA","Harvard School of Public Health, 677 Huntington Ave, Boston, MA, 2115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Ave., Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard School of Public Health, 677 Huntington Ave, Boston, MA, 2115, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045751903","display_name":"Robert L. Barbieri","orcid":"https://orcid.org/0000-0003-3918-038X","observed_orcids":["https://orcid.org/0000-0003-3918-038X"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert L Barbieri","raw_affiliation_strings":["Department of Obstetrics, Gynecology, and Reproductive Medicine, Brigham and Women's Hospital, 75 Francis St., Boston, MA, 02115, USA","Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology, and Reproductive Medicine, Brigham and Women's Hospital, 75 Francis St., Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008373933","display_name":"Susan E. Hankinson","orcid":"https://orcid.org/0000-0001-9155-3767","observed_orcids":["https://orcid.org/0000-0001-9155-3767"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I24603500","display_name":"University of Massachusetts Amherst","ror":"https://ror.org/0072zz521","country_code":"US","type":"education","lineage":["https://openalex.org/I24603500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan E Hankinson","raw_affiliation_strings":["Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Ave., Boston, MA, 02115, USA","Division of Biostatistics and Epidemiology, University of Massachusetts, 715 N. Pleasant St, Amherst, MA, 01002, USA","Harvard School of Public Health, 677 Huntington Ave, Boston, MA, 2115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Ave., Boston, MA, 02115, USA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Division of Biostatistics and Epidemiology, University of Massachusetts, 715 N. Pleasant St, Amherst, MA, 01002, USA","institution_ids":["https://openalex.org/I24603500"]},{"raw_affiliation_string":"Harvard School of Public Health, 677 Huntington Ave, Boston, MA, 2115, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5059302865"],"corresponding_institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":{"value":4190,"currency":"USD","value_usd":4190},"fwci":5.2793,"has_fulltext":true,"cited_by_count":79,"citation_normalized_percentile":{"value":0.97174021,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"15","issue":"2","first_page":"R19","last_page":"R19"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.5005000233650208,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.5005000233650208,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors","score":0.4699999988079071,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.019899999722838402,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer-risk","display_name":"breast cancer risk","score":0.8759999871253967},{"id":"https://openalex.org/keywords/premenopausal-women","display_name":"premenopausal women","score":0.9810000061988831},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.8679999709129333},{"id":"https://openalex.org/keywords/estrone","display_name":"estrone","score":0.8320000171661377},{"id":"https://openalex.org/keywords/free-estradiol","display_name":"free estradiol","score":0.8429999947547913},{"id":"https://openalex.org/keywords/progesterone","display_name":"progesterone","score":0.8619999885559082},{"id":"https://openalex.org/keywords/androgens","display_name":"androgens","score":0.9120000004768372},{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.9779999852180481},{"id":"https://openalex.org/keywords/dehydroepiandrosterone-sulfate","display_name":"dehydroepiandrosterone sulfate","score":0.9929999709129333},{"id":"https://openalex.org/keywords/sex-hormone-binding-globulin","display_name":"sex hormone-binding globulin","score":0.9950000047683716},{"id":"https://openalex.org/keywords/estrogen-receptor-positive","display_name":"estrogen receptor-positive","score":0.7110000252723694},{"id":"https://openalex.org/keywords/progesterone-receptor-positive","display_name":"progesterone receptor-positive","score":0.9940000176429749},{"id":"https://openalex.org/keywords/menopausal-status","display_name":"menopausal status","score":0.7599999904632568}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7460764646530151},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7292805314064026},{"id":"https://openalex.org/C2778656385","wikidata":"https://www.wikidata.org/wiki/Q414986","display_name":"Estrone","level":3,"score":0.5991292595863342},{"id":"https://openalex.org/C30092816","wikidata":"https://www.wikidata.org/wiki/Q419613","display_name":"Sex hormone-binding globulin","level":4,"score":0.5974968671798706},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5800080299377441},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5525359511375427},{"id":"https://openalex.org/C143228043","wikidata":"https://www.wikidata.org/wiki/Q2363481","display_name":"Luteal phase","level":3,"score":0.5330883860588074},{"id":"https://openalex.org/C2779058012","wikidata":"https://www.wikidata.org/wiki/Q83864","display_name":"Menstrual cycle","level":3,"score":0.5248851180076599},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.5019385814666748},{"id":"https://openalex.org/C148759681","wikidata":"https://www.wikidata.org/wiki/Q2005375","display_name":"Nurses' Health Study","level":3,"score":0.4665023684501648},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.45678457617759705},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.45658108592033386},{"id":"https://openalex.org/C146304588","wikidata":"https://www.wikidata.org/wiki/Q961652","display_name":"Case-control study","level":2,"score":0.44940656423568726},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4489891529083252},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4392701983451843},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.42716100811958313},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4245394468307495},{"id":"https://openalex.org/C2778562196","wikidata":"https://www.wikidata.org/wiki/Q177708","display_name":"Menopause","level":2,"score":0.41133415699005127},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.31929653882980347},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.2445717751979828}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000728","descriptor_name":"Androgens","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004958","descriptor_name":"Estradiol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009726","descriptor_name":"Nurses","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D011374","descriptor_name":"Progesterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012738","descriptor_name":"Sex Hormone-Binding Globulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016387","descriptor_name":"Women's Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017697","descriptor_name":"Premenopause","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1186/bcr3394","doi":"https://doi.org/10.1186/bcr3394","is_oa":true,"landing_page_url":"https://doi.org/10.1186/bcr3394","pdf_url":"https://breast-cancer-research.biomedcentral.com/counter/pdf/10.1186/bcr3394","source":{"id":"https://openalex.org/S42140187","display_name":"Breast Cancer Research","issn_l":"1465-5411","issn":["1465-5411","1465-542X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Breast Cancer Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2672478","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3672790","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3672790","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3672790","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Breast Cancer Res","raw_type":"Text"},{"id":"pmid:23497468","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23497468","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Breast cancer research : BCR","raw_type":"Comparative Study"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.773.3819","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.773.3819","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/d2/e3/bcr3394.PMC3672790.pdf","raw_type":"text"},{"id":"pmh:oai:dash.harvard.edu:1/11708570","doi":null,"is_oa":true,"landing_page_url":"http://nrs.harvard.edu/urn-3:HUL.InstRepos:11708570","pdf_url":null,"source":{"id":"https://openalex.org/S4306401540","display_name":"Digital Access to Scholarship at Harvard (DASH) (Harvard University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I136199984","host_organization_name":"Harvard University","host_organization_lineage":["https://openalex.org/I136199984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:works.bepress.com:susan_hankinson-1057","doi":null,"is_oa":true,"landing_page_url":"https://works.bepress.com/susan_hankinson/29","pdf_url":null,"source":{"id":"https://openalex.org/S4306402240","display_name":"ScholarWorks@UMassAmherst (University of Massachusetts Amherst)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I24603500","host_organization_name":"University of Massachusetts Amherst","host_organization_lineage":["https://openalex.org/I24603500"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Susan E. Hankinson","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1186/bcr3394","doi":"https://doi.org/10.1186/bcr3394","is_oa":true,"landing_page_url":"https://doi.org/10.1186/bcr3394","pdf_url":"https://breast-cancer-research.biomedcentral.com/counter/pdf/10.1186/bcr3394","source":{"id":"https://openalex.org/S42140187","display_name":"Breast Cancer Research","issn_l":"1465-5411","issn":["1465-5411","1465-542X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Breast Cancer Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G3602225402","display_name":null,"funder_award_id":"CA67262","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G756856000","display_name":"Risk Factors for Breast Cancer in Younger Nurses","funder_award_id":"R01CA050385","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000868044","display_name":"Program for Training in Cancer Epidemiology","funder_award_id":"T32CA009001","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2136934360.pdf","grobid_xml":"https://content.openalex.org/works/W2136934360.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W1511930757","https://openalex.org/W1881162395","https://openalex.org/W1918579068","https://openalex.org/W1927711487","https://openalex.org/W1952381273","https://openalex.org/W1964172805","https://openalex.org/W1967607481","https://openalex.org/W1969456163","https://openalex.org/W1981843591","https://openalex.org/W2000766198","https://openalex.org/W2008021904","https://openalex.org/W2012345238","https://openalex.org/W2015784383","https://openalex.org/W2017712076","https://openalex.org/W2026268878","https://openalex.org/W2028691872","https://openalex.org/W2030086348","https://openalex.org/W2054339472","https://openalex.org/W2061975232","https://openalex.org/W2073573977","https://openalex.org/W2078278015","https://openalex.org/W2087670482","https://openalex.org/W2100560530","https://openalex.org/W2102681491","https://openalex.org/W2103038661","https://openalex.org/W2112025328","https://openalex.org/W2115379774","https://openalex.org/W2115651934","https://openalex.org/W2119237938","https://openalex.org/W2122025671","https://openalex.org/W2130343048","https://openalex.org/W2130958872","https://openalex.org/W2133100322","https://openalex.org/W2135847690","https://openalex.org/W2143927632","https://openalex.org/W2145821437","https://openalex.org/W2155533563","https://openalex.org/W2157586615","https://openalex.org/W2161200908","https://openalex.org/W2163571791","https://openalex.org/W2169553654","https://openalex.org/W2410866476","https://openalex.org/W2464908612","https://openalex.org/W4235221123","https://openalex.org/W4249736868"],"related_works":["https://openalex.org/W7098222651","https://openalex.org/W2112025328","https://openalex.org/W2095975680","https://openalex.org/W2103369932","https://openalex.org/W2163571791","https://openalex.org/W2054339472","https://openalex.org/W157836986","https://openalex.org/W2149056065","https://openalex.org/W1992405425","https://openalex.org/W2285443694"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Prior":[1],"research":[2],"supports":[3],"an":[4],"association":[5,17,151],"between":[6,29,88,152],"endogenous":[7],"sex":[8,34],"steroids":[9],"and":[10,33,39,55,69,90,92,100,145,156,159,204,238,296,330,384],"breast":[11,40,86,113,140,166,266,284,320,386],"cancer":[12,41,87,114,267,321,387],"among":[13,21],"postmenopausal":[14,301,385],"women;":[15],"the":[16,27,48,73,220,373,379],"is":[18],"less":[19],"clear":[20],"premenopausal":[22,81,137,288,376,383],"women.":[23],"METHODS:":[24],"We":[25,106],"evaluated":[26],"associations":[28,327,347],"estrogens,":[30],"androgens,":[31],"progesterone":[32,205],"hormone":[35],"binding":[36],"globulin":[37],"(SHBG)":[38],"in":[42,47,66,286,322,378],"a":[43],"nested":[44],"case-control":[45],"study":[46],"Nurses'":[49],"Health":[50],"Study":[51],"II.":[52],"Between":[53],"1996":[54],"1999,":[56],"29,611":[57],"participants":[58],"provided":[59,63],"blood":[60,83],"samples;":[61],"18,521":[62],"samples":[64],"timed":[65,104],"early":[67],"follicular":[68,153,278,354],"mid-luteal":[70],"phases":[71],"of":[72,78,136,161,319,375,381],"menstrual":[74],"cycle.":[75],"A":[76],"total":[77,163],"634":[79],"women,":[80],"at":[82,275,289,362],"collection,":[84],"developed":[85],"1999":[89],"2009":[91],"were":[93,206,212,313,337,348,367],"matched":[94],"to":[95,195,224,233,245,256,294,306,371],"1,264":[96],"controls":[97,102],"(514":[98],"cases":[99],"1,030":[101],"with":[103,173,209,217,265,277,283,300,315,325,340,350,353],"samples).":[105],"used":[107,129],"conditional":[108],"logistic":[109,121],"regression":[110,122],"controlling":[111,124],"for":[112,117,125,130,328],"risk":[115,160,218,318],"factors":[116,127],"overall":[118],"analyses;":[119],"unconditional":[120],"additionally":[123],"matching":[126],"was":[128,149,170,222,262],"subgroup":[131],"analyses.":[132],"RESULTS:":[133],"In":[134],"analyses":[135],"estrogens":[138,356],"including":[139],"cancers":[141,181,285],"diagnosed":[142],"both":[143,382],"before":[144],"after":[146],"menopause,":[147],"there":[148],"no":[150,344],"estradiol,":[154],"estrone":[155],"free":[157,202],"estradiol":[158,169,203,279,335],"either":[162],"or":[164,214],"invasive":[165,225,329],"cancer.":[167],"Luteal":[168,200,333],"positively":[171,281],"associated":[172,208,216,264,282,299,314,339],"estrogen":[174],"receptor":[175,178],"positive":[176,179],"(ER+)/progesterone":[177],"(PR+)":[180],"(5th":[182],"vs.":[183],"1st":[184],"quintile":[185],"odds":[186],"ratio":[187],"(OR):":[188],"1.7":[189,243],"(95%":[190],"confidence":[191],"interval":[192],"(CI):":[193],"1.0":[194],"2.9),":[196],"Ptrend":[197,235,247,258],"=":[198,236,248,259],"0.02).":[199],"estrone,":[201],"not":[207,263],"risk.":[210,268],"Androgens":[211,312],"suggestively":[213,280,338],"significantly":[215,297],"when":[219],"sample":[221],"restricted":[223],"tumors":[226,342],"(for":[227],"example,":[228],"testosterone:":[229],"OR:":[230,242,253],"1.4":[231],"(1.0":[232],"2.0),":[234],"0.23)":[237],"ER+/PR+":[239,331,341],"disease":[240,302],"(testosterone:":[241],"(1.1":[244],"2.6)":[246],"0.10;":[249],"dehydroepiandrosterone":[250],"sulfate":[251],"(DHEAS)":[252],"1.3":[254],"(0.8":[255],"2.0)":[257],"0.05).":[260],"SHBG":[261],"The":[269],"results":[270],"varied":[271],"by":[272,359],"menopausal":[273,360],"status":[274,361],"diagnosis,":[276,363],"women":[287],"diagnosis":[290],"(OR:":[291,303],"1.1":[292],"(0.9":[293],"1.3)":[295],"inversely":[298],"0.6":[304],"(0.4":[305],"0.9);":[307],"Pheterogeneity":[308],"<":[309],"0.01).":[310],"CONCLUSIONS:":[311],"modestly":[316],"increased":[317],"this":[323],"population,":[324],"stronger":[326],"disease.":[332],"phase":[334,355],"levels":[336],"but":[343,364],"other":[345],"strong":[346],"observed":[349],"estrogens.":[351],"Associations":[352],"may":[357],"vary":[358],"case":[365],"numbers":[366],"limited.":[368],"Additional":[369],"studies":[370],"confirm":[372],"role":[374],"hormones":[377],"etiology":[380],"are":[388],"needed.":[389]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":6}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}