{"id":"https://openalex.org/W2136606606","doi":"https://doi.org/10.1002/ccd.22418","title":"Prognostic benefit of transcatheter aortic valve implantation compared with medical therapy in patients with inoperable aortic stenosis","display_name":"Prognostic benefit of transcatheter aortic valve implantation compared with medical therapy in patients with inoperable aortic stenosis","publication_year":2009,"publication_date":"2009-12-22","ids":{"openalex":"https://openalex.org/W2136606606","doi":"https://doi.org/10.1002/ccd.22418","mag":"2136606606","pmid":"https://pubmed.ncbi.nlm.nih.gov/20146205"},"language":"en","primary_location":{"id":"doi:10.1002/ccd.22418","doi":"https://doi.org/10.1002/ccd.22418","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ccd.22418","pdf_url":null,"source":{"id":"https://openalex.org/S41314575","display_name":"Catheterization and Cardiovascular Interventions","issn_l":"1522-1946","issn":["1522-1946","1522-726X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Catheterization and Cardiovascular Interventions","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082544361","display_name":"Ronak Rajani","orcid":"https://orcid.org/0000-0002-8816-6296","observed_orcids":["https://orcid.org/0000-0002-8816-6296"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ronak Rajani","raw_affiliation_strings":["Sussex Cardiac Centre, Brighton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sussex Cardiac Centre, Brighton, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"William Buxton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800342113","display_name":"Royal Sussex County Hospital","ror":"https://ror.org/05fe2n505","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800342113","https://openalex.org/I4210151332"]},{"id":"https://openalex.org/I4387152291","display_name":"Brighton and Sussex University Hospitals NHS Trust","ror":"https://ror.org/02dqrks84","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210151332","https://openalex.org/I4387152291"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"William Buxton","raw_affiliation_strings":["Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom","institution_ids":["https://openalex.org/I2800342113","https://openalex.org/I4387152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063491485","display_name":"Peter Haworth","orcid":"https://orcid.org/0009-0004-2762-0127","observed_orcids":["https://orcid.org/0009-0004-2762-0127"]},"institutions":[{"id":"https://openalex.org/I2800342113","display_name":"Royal Sussex County Hospital","ror":"https://ror.org/05fe2n505","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800342113","https://openalex.org/I4210151332"]},{"id":"https://openalex.org/I4387152291","display_name":"Brighton and Sussex University Hospitals NHS Trust","ror":"https://ror.org/02dqrks84","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210151332","https://openalex.org/I4387152291"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter Haworth","raw_affiliation_strings":["Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom","institution_ids":["https://openalex.org/I2800342113","https://openalex.org/I4387152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110069643","display_name":"Muhammed Zeeshan Khawaja","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800342113","display_name":"Royal Sussex County Hospital","ror":"https://ror.org/05fe2n505","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800342113","https://openalex.org/I4210151332"]},{"id":"https://openalex.org/I4387152291","display_name":"Brighton and Sussex University Hospitals NHS Trust","ror":"https://ror.org/02dqrks84","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210151332","https://openalex.org/I4387152291"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Muhammed Z. Khawaja","raw_affiliation_strings":["Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom","institution_ids":["https://openalex.org/I2800342113","https://openalex.org/I4387152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080825817","display_name":"Manav Sohal","orcid":"https://orcid.org/0000-0002-5771-5504","observed_orcids":["https://orcid.org/0000-0002-5771-5504"]},"institutions":[{"id":"https://openalex.org/I2800342113","display_name":"Royal Sussex County Hospital","ror":"https://ror.org/05fe2n505","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800342113","https://openalex.org/I4210151332"]},{"id":"https://openalex.org/I4387152291","display_name":"Brighton and Sussex University Hospitals NHS Trust","ror":"https://ror.org/02dqrks84","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210151332","https://openalex.org/I4387152291"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Manav Sohal","raw_affiliation_strings":["Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom","institution_ids":["https://openalex.org/I2800342113","https://openalex.org/I4387152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113835952","display_name":"Roberta Lima Brum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800342113","display_name":"Royal Sussex County Hospital","ror":"https://ror.org/05fe2n505","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800342113","https://openalex.org/I4210151332"]},{"id":"https://openalex.org/I4387152291","display_name":"Brighton and Sussex University Hospitals NHS Trust","ror":"https://ror.org/02dqrks84","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210151332","https://openalex.org/I4387152291"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Roberta L. Brum","raw_affiliation_strings":["Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom","institution_ids":["https://openalex.org/I2800342113","https://openalex.org/I4387152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056820883","display_name":"Nevil Hutchinson","orcid":"https://orcid.org/0000-0002-6326-0067","observed_orcids":["https://orcid.org/0000-0002-6326-0067"]},"institutions":[{"id":"https://openalex.org/I2800342113","display_name":"Royal Sussex County Hospital","ror":"https://ror.org/05fe2n505","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800342113","https://openalex.org/I4210151332"]},{"id":"https://openalex.org/I4387152291","display_name":"Brighton and Sussex University Hospitals NHS Trust","ror":"https://ror.org/02dqrks84","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210151332","https://openalex.org/I4387152291"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nevil Hutchinson","raw_affiliation_strings":["Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom","institution_ids":["https://openalex.org/I2800342113","https://openalex.org/I4387152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018884922","display_name":"Adam de Belder","orcid":"https://orcid.org/0000-0003-0198-4526","observed_orcids":["https://orcid.org/0000-0003-0198-4526"]},"institutions":[{"id":"https://openalex.org/I2800342113","display_name":"Royal Sussex County Hospital","ror":"https://ror.org/05fe2n505","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800342113","https://openalex.org/I4210151332"]},{"id":"https://openalex.org/I4387152291","display_name":"Brighton and Sussex University Hospitals NHS Trust","ror":"https://ror.org/02dqrks84","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210151332","https://openalex.org/I4387152291"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Adam de Belder","raw_affiliation_strings":["Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom","institution_ids":["https://openalex.org/I2800342113","https://openalex.org/I4387152291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021116484","display_name":"Uday Trivedi","orcid":"https://orcid.org/0000-0002-7078-2760","observed_orcids":["https://orcid.org/0000-0002-7078-2760"]},"institutions":[{"id":"https://openalex.org/I2800342113","display_name":"Royal Sussex County Hospital","ror":"https://ror.org/05fe2n505","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800342113","https://openalex.org/I4210151332"]},{"id":"https://openalex.org/I4387152291","display_name":"Brighton and Sussex University Hospitals NHS Trust","ror":"https://ror.org/02dqrks84","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210151332","https://openalex.org/I4387152291"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Uday Trivedi","raw_affiliation_strings":["Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, United Kingdom","institution_ids":["https://openalex.org/I2800342113","https://openalex.org/I4387152291"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069601173","display_name":"David Hildick\u2010Smith","orcid":"https://orcid.org/0000-0002-1147-1436","observed_orcids":["https://orcid.org/0000-0002-1147-1436"]},"institutions":[{"id":"https://openalex.org/I4387152291","display_name":"Brighton and Sussex University Hospitals NHS Trust","ror":"https://ror.org/02dqrks84","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210151332","https://openalex.org/I4387152291"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David Hildick\u2010Smith","raw_affiliation_strings":["Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Eastern Road, Brighton, BN2 5BE, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Eastern Road, Brighton, BN2 5BE, United Kingdom","institution_ids":["https://openalex.org/I4387152291"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4490,"currency":"USD","value_usd":4490},"apc_paid":null,"fwci":3.3853,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.93118198,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"75","issue":"7","first_page":"1121","last_page":"1126"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11551","display_name":"Infective Endocarditis Diagnosis and Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcatheter-aortic-valve-replacement","display_name":"transcatheter aortic valve implantation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/medical-management","display_name":"medical management","score":0.7070000171661377},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.9359999895095825},{"id":"https://openalex.org/keywords/euroscore","display_name":"EuroSCORE","score":0.7179999947547913},{"id":"https://openalex.org/keywords/procedural-mortality","display_name":"procedural mortality","score":0.6449999809265137},{"id":"https://openalex.org/keywords/aortic-valve-replacement","display_name":"aortic valve replacement","score":0.4729999899864197},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.4650000035762787}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.977007269859314},{"id":"https://openalex.org/C2781436128","wikidata":"https://www.wikidata.org/wiki/Q4778764","display_name":"Aortic valvuloplasty","level":4,"score":0.8119428157806396},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.7384827136993408},{"id":"https://openalex.org/C2781414266","wikidata":"https://www.wikidata.org/wiki/Q531019","display_name":"Aortic valve stenosis","level":3,"score":0.5287777185440063},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5256872177124023},{"id":"https://openalex.org/C2780714102","wikidata":"https://www.wikidata.org/wiki/Q616071","display_name":"Aortic valve","level":2,"score":0.5078759789466858},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.49369463324546814},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4820888340473175},{"id":"https://openalex.org/C2776570981","wikidata":"https://www.wikidata.org/wiki/Q4413093","display_name":"Aortic valve replacement","level":3,"score":0.4510931968688965}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001024","descriptor_name":"Aortic Valve Stenosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001024","descriptor_name":"Aortic Valve Stenosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001024","descriptor_name":"Aortic Valve Stenosis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D001024","descriptor_name":"Aortic Valve Stenosis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D002317","descriptor_name":"Cardiovascular Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002404","descriptor_name":"Catheterization","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006328","descriptor_name":"Cardiac Catheterization","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019918","descriptor_name":"Heart Valve Prosthesis Implantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019918","descriptor_name":"Heart Valve Prosthesis Implantation","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/ccd.22418","doi":"https://doi.org/10.1002/ccd.22418","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ccd.22418","pdf_url":null,"source":{"id":"https://openalex.org/S41314575","display_name":"Catheterization and Cardiovascular Interventions","issn_l":"1522-1946","issn":["1522-1946","1522-726X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Catheterization and Cardiovascular Interventions","raw_type":"journal-article"},{"id":"pmid:20146205","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20146205","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W163579839","https://openalex.org/W180423479","https://openalex.org/W1507413178","https://openalex.org/W1964589386","https://openalex.org/W1969332989","https://openalex.org/W1986040002","https://openalex.org/W2013852238","https://openalex.org/W2038578901","https://openalex.org/W2047531176","https://openalex.org/W2054436867","https://openalex.org/W2077649368","https://openalex.org/W2108349586","https://openalex.org/W2111988269","https://openalex.org/W2122473579","https://openalex.org/W2138768506","https://openalex.org/W2143682438","https://openalex.org/W2156202966","https://openalex.org/W2158490705","https://openalex.org/W2163674015","https://openalex.org/W2166323360","https://openalex.org/W2167332311","https://openalex.org/W2320913451","https://openalex.org/W2326142435","https://openalex.org/W3112663317","https://openalex.org/W4250071522"],"related_works":["https://openalex.org/W67502470","https://openalex.org/W2508356714","https://openalex.org/W2328355948","https://openalex.org/W2092690465","https://openalex.org/W2543259917","https://openalex.org/W2003641213","https://openalex.org/W2402325750","https://openalex.org/W3136797302","https://openalex.org/W2302663761","https://openalex.org/W2139151408"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"compare":[2],"survival":[3,24,213],"in":[4,63,104],"patients":[5,26,38,51,65,85,129,144,149],"with":[6,27,55,66,208,247,267],"inoperable":[7],"aortic":[8,13,30,41,69,98,206,249,258,269],"stenosis":[9,31,70],"who":[10,52,71,252],"undergo":[11],"transcatheter":[12,40,268],"valve":[14,42,99,250,259,270],"implantation":[15,43,271],"against":[16],"those":[17],"managed":[18],"medically.":[19],"BACKGROUND:":[20],"Without":[21],"surgical":[22,257],"correction,":[23],"of":[25,120,137,220,229],"severe":[28,67,248],"symptomatic":[29,68],"is":[32,35],"poor.":[33],"It":[34],"unknown":[36],"whether":[37],"undergoing":[39],"(TAVI)":[44],"have":[45,261],"a":[46,209,227],"better":[47],"prognosis":[48,264],"than":[49,273],"similar":[50],"are":[53,253],"treated":[54,266],"medical":[56,78,163,179,276],"management.":[57],"METHODS:":[58],"Survival":[59],"rates":[60],"were":[61,102,140,150,226],"compared":[62],"consecutive":[64],"either":[72],"underwent":[73,145,203],"TAVI":[74,146,170,232],"or":[75,90,106,157],"continued":[76],"on":[77,154,162,275],"management":[79,277],"following":[80],"multidisciplinary":[81],"team":[82],"assessment.":[83],"All":[84],"had":[86],"been":[87],"turned":[88],"down,":[89],"considered":[91],"at":[92],"unacceptably":[93],"high":[94],"risk,":[95],"for":[96,168,177,256],"conventional":[97],"surgery.":[100],"Patients":[101,246],"reviewed":[103],"clinic":[105],"by":[107],"telephone":[108],"six":[109],"monthly.":[110],"Mortality":[111],"data":[112],"was":[113,172,190,195],"obtained":[114],"from":[115],"the":[116,169,178,198],"United":[117],"Kingdom":[118],"Office":[119],"National":[121],"Statistics.":[122],"RESULTS:":[123],"The":[124,165],"study":[125],"group":[126,171,180],"included":[127],"85":[128],"aged":[130],"81":[131],"+/-":[132,174,182,222],"7":[133],"years":[134],"(range":[135],"62-94),":[136],"whom":[138],"48":[139],"male.":[141],"Thirty":[142],"eight":[143],"while":[147],"47":[148],"deemed":[151],"unsuitable":[152],"based":[153],"echocardiographic,":[155],"angiographic,":[156],"clinical":[158],"criteria":[159],"and":[160,176,192],"remained":[161],"therapy.":[164],"calculated":[166],"EuroSCORE":[167],"11":[173],"2":[175,183],"9":[181],"(P":[184,214,242],"<":[185],"0.001).":[186],"TAVI-related":[187],"procedural":[188],"mortality":[189,194],"2.6%,":[191],"30-day":[193],"5.2%.":[196],"Among":[197],"medically-treated":[199],"patients,":[200],"14":[201],"(30%)":[202],"palliative":[204],"balloon":[205],"valvuloplasty,":[207],"trend":[210],"toward":[211],"improved":[212,263],"=":[215,234,239,243],"0.06).":[216],"During":[217],"overall":[218],"follow-up":[219],"215":[221],"115":[223],"days":[224],"there":[225],"total":[228],"18":[230],"deaths;":[231],"N":[233,238],"5":[235],"(13%);":[236],"Medical":[237],"13":[240],"(28%)":[241],"0.04).":[244],"CONCLUSIONS:":[245],"disease":[251],"not":[254],"suitable":[255],"replacement":[260],"an":[262],"if":[265],"rather":[272],"continuing":[274],"alone.":[278]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":12}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}