{"id":"https://openalex.org/W2136289540","doi":null,"title":"Acute attack of AIP (acute intermittent porphyria) with severe vivax malaria associated with convulsions: a case report.","display_name":"Acute attack of AIP (acute intermittent porphyria) with severe vivax malaria associated with convulsions: a case report.","publication_year":2009,"publication_date":"2009-12-01","ids":{"openalex":"https://openalex.org/W2136289540","mag":"2136289540","pmid":"https://pubmed.ncbi.nlm.nih.gov/19959859"},"language":"en","primary_location":{"id":"pmid:19959859","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19959859","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of vector borne diseases","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/c1952eafef5a49c1b84c3f03e501f5df","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110566856","display_name":"Sanjay Kumar Kochar","orcid":"https://orcid.org/0000-0002-4126-5991","observed_orcids":["https://orcid.org/0000-0002-4126-5991"]},"institutions":[{"id":"https://openalex.org/I2800123788","display_name":"Sardar Patel Medical College","ror":"https://ror.org/0099kc363","country_code":"IN","type":"education","lineage":["https://openalex.org/I2800123788"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sanjay K Kochar","raw_affiliation_strings":["Department of Medicine, S.P. Medical College, Bikaner, India. drdkkochar@yahoo.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, S.P. Medical College, Bikaner, India. drdkkochar@yahoo.com","institution_ids":["https://openalex.org/I2800123788"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Manish Mahajan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Manish Mahajan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Rajendra P Gupta","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rajendra P Gupta","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037144805","display_name":"Sheetal Middha","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sheetal Middha","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110179976","display_name":"Jyoti Acharya","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jyoti Acharya","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112005612","display_name":"Abhishek Kochar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Abhishek Kochar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112015131","display_name":"Ashis Das","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ashis Das","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111939676","display_name":"Dhanpat Kumar Kochar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dhanpat K Kochar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4395,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.58451172,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"46","issue":"4","first_page":"307","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12441","display_name":"Porphyrin Metabolism and Disorders","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12441","display_name":"Porphyrin Metabolism and Disorders","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12068","display_name":"Neonatal Health and Biochemistry","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-intermittent-porphyria","display_name":"acute intermittent porphyria","score":1.0},{"id":"https://openalex.org/keywords/vivax-malaria","display_name":"vivax malaria","score":0.8579999804496765},{"id":"https://openalex.org/keywords/severe-malaria","display_name":"severe malaria","score":0.8420000076293945},{"id":"https://openalex.org/keywords/convulsions","display_name":"convulsions","score":0.8930000066757202},{"id":"https://openalex.org/keywords/cerebral-malaria","display_name":"cerebral malaria","score":0.8479999899864197},{"id":"https://openalex.org/keywords/porphobilinogen-deaminase-deficiency","display_name":"porphobilinogen deaminase deficiency","score":0.9509999752044678},{"id":"https://openalex.org/keywords/antimalarial-drug-safety","display_name":"antimalarial drug safety","score":0.7839999794960022},{"id":"https://openalex.org/keywords/hepatic-porphyria","display_name":"hepatic porphyria","score":0.6980000138282776},{"id":"https://openalex.org/keywords/differential-diagnosis-of-seizures","display_name":"differential diagnosis of seizures","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C2779028619","wikidata":"https://www.wikidata.org/wiki/Q424247","display_name":"Acute intermittent porphyria","level":3,"score":0.8407458066940308},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7113472819328308},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5866844654083252},{"id":"https://openalex.org/C2777940757","wikidata":"https://www.wikidata.org/wiki/Q271759","display_name":"Porphyria","level":2,"score":0.49600109457969666},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.4895728528499603},{"id":"https://openalex.org/C2780955771","wikidata":"https://www.wikidata.org/wiki/Q183425","display_name":"Abdominal pain","level":2,"score":0.46041256189346313},{"id":"https://openalex.org/C2778503633","wikidata":"https://www.wikidata.org/wiki/Q415227","display_name":"Porphobilinogen deaminase","level":4,"score":0.43559974431991577},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.425136923789978},{"id":"https://openalex.org/C2780852908","wikidata":"https://www.wikidata.org/wiki/Q127076","display_name":"Vomiting","level":2,"score":0.41947540640830994},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30172741413116455},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29853612184524536},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.096885085105896}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D016780","descriptor_name":"Malaria, Vivax","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D016780","descriptor_name":"Malaria, Vivax","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D017118","descriptor_name":"Porphyria, Acute Intermittent","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"pmid:19959859","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19959859","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of vector borne diseases","raw_type":"Case Reports"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.561.6766","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.561.6766","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.mrcindia.org/journal/issues/464307.pdf","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:c1952eafef5a49c1b84c3f03e501f5df","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c1952eafef5a49c1b84c3f03e501f5df","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Vector Borne Diseases, Vol 46, Iss 4, Pp 307-309 (2009)","raw_type":"article"},{"id":"mag:2136289540","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19959859","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:c1952eafef5a49c1b84c3f03e501f5df","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c1952eafef5a49c1b84c3f03e501f5df","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Vector Borne Diseases, Vol 46, Iss 4, Pp 307-309 (2009)","raw_type":"article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1521892271","https://openalex.org/W2008281391","https://openalex.org/W2054335933","https://openalex.org/W2056313634","https://openalex.org/W2116376267","https://openalex.org/W2431752438","https://openalex.org/W2571488753"],"related_works":["https://openalex.org/W7095536395","https://openalex.org/W2306646116","https://openalex.org/W1965362512","https://openalex.org/W2002159547","https://openalex.org/W2275441367","https://openalex.org/W2239455887","https://openalex.org/W4306352895","https://openalex.org/W2071911701","https://openalex.org/W2890942267","https://openalex.org/W140518809"],"abstract_inverted_index":{"Key":[0],"words":[1],"Acute":[2,12],"intermittent":[3,13],"porphyria":[4,14,20],"\u2013":[5,7,9],"convulsions":[6,75],"malaria":[8],"Plasmodium":[10,90],"vivax":[11,91],"(AIP)":[15],"is":[16,47,76],"a":[17],"hereditary":[18],"hepatic":[19],"inherited":[21],"as":[22],"autosomal":[23],"dominant":[24],"with":[25],"low":[26],"penetrance":[27],"resulting":[28],"from":[29],"mutation":[30],"in":[31,101],"the":[32,35,51,68],"gene":[33],"encoding":[34],"enzyme,":[36],"porphobilinogen":[37],"deami-nase":[38],"(PBG-D)":[39],"[hydroxymethylbilane":[40],"synthase,":[41],"uroporphyrinogen":[42],"I":[43],"synthase].":[44],"The":[45],"diagnosis":[46],"of-ten":[48],"obscured":[49],"by":[50,67],"variable":[52,69],"presentation,":[53],"viz.":[54],"ab-dominal":[55],"pain":[56],"(commonest),":[57],"constipation,":[58],"vomiting,":[59],"convulsions,":[60],"and":[61,64],"peripheral":[62],"neuropathy":[63],"further":[65],"complicated":[66],"course":[70],"of":[71,74,85],"illness.":[72],"Inci-dence":[73],"10\u201320":[77],"%":[78],"but":[79],"there":[80],"may":[81],"be":[82],"presenting":[83],"symptom":[84],"an":[86],"acute":[87],"relapse1,2.":[88],"Although":[89],"usually":[92],"causes":[93],"benign":[94],"uncompli-cated":[95],"malaria,":[96],"it":[97],"can":[98],"occasionally":[99],"result":[100],"severe":[102],"dis-":[103]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}